ATE394162T1 - Vorrichtung zur herstellung von mikromatrizen wobei die vorrichtung in inkrementellen etappen mechanisch eingestellt wird - Google Patents

Vorrichtung zur herstellung von mikromatrizen wobei die vorrichtung in inkrementellen etappen mechanisch eingestellt wird

Info

Publication number
ATE394162T1
ATE394162T1 AT01937586T AT01937586T ATE394162T1 AT E394162 T1 ATE394162 T1 AT E394162T1 AT 01937586 T AT01937586 T AT 01937586T AT 01937586 T AT01937586 T AT 01937586T AT E394162 T1 ATE394162 T1 AT E394162T1
Authority
AT
Austria
Prior art keywords
micromatrices
producing
mechanically adjusted
incremental stages
plate
Prior art date
Application number
AT01937586T
Other languages
English (en)
Inventor
Patrick Cleveland
Original Assignee
V & P Scient Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by V & P Scient Inc filed Critical V & P Scient Inc
Application granted granted Critical
Publication of ATE394162T1 publication Critical patent/ATE394162T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/0046—Sequential or parallel reactions, e.g. for the synthesis of polypeptides or polynucleotides; Apparatus and devices for combinatorial chemistry or for making molecular arrays
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y30/00—Nanotechnology for materials or surface science, e.g. nanocomposites
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/00351—Means for dispensing and evacuation of reagents
    • B01J2219/00387—Applications using probes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/00497—Features relating to the solid phase supports
    • B01J2219/00527—Sheets
    • B01J2219/00533—Sheets essentially rectangular
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/00497—Features relating to the solid phase supports
    • B01J2219/00527—Sheets
    • B01J2219/00536—Sheets in the shape of disks
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00585—Parallel processes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00596—Solid-phase processes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00603—Making arrays on substantially continuous surfaces
    • B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00603—Making arrays on substantially continuous surfaces
    • B01J2219/00659—Two-dimensional arrays
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00583—Features relative to the processes being carried out
    • B01J2219/00603—Making arrays on substantially continuous surfaces
    • B01J2219/00677—Ex-situ synthesis followed by deposition on the substrate
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00718—Type of compounds synthesised
    • B01J2219/0072—Organic compounds
    • B01J2219/00722—Nucleotides
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00718—Type of compounds synthesised
    • B01J2219/0072—Organic compounds
    • B01J2219/00725—Peptides
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/02—Adapting objects or devices to another
    • B01L2200/025—Align devices or objects to ensure defined positions relative to each other
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/02—Drop detachment mechanisms of single droplets from nozzles or pins
    • B01L2400/022—Drop detachment mechanisms of single droplets from nozzles or pins droplet contacts the surface of the receptacle
    • B01L2400/025—Drop detachment mechanisms of single droplets from nozzles or pins droplet contacts the surface of the receptacle tapping tip on substrate
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/02—Burettes; Pipettes
    • B01L3/0241—Drop counters; Drop formers
    • B01L3/0244—Drop counters; Drop formers using pins
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B60/00—Apparatus specially adapted for use in combinatorial chemistry or with libraries
    • C40B60/14—Apparatus specially adapted for use in combinatorial chemistry or with libraries for creating libraries
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N2035/1027—General features of the devices
    • G01N2035/1034—Transferring microquantities of liquid
    • G01N2035/1037—Using surface tension, e.g. pins or wires
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1081—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices characterised by the means for relatively moving the transfer device and the containers in an horizontal plane
    • G01N35/1083—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices characterised by the means for relatively moving the transfer device and the containers in an horizontal plane with one horizontal degree of freedom
    • G01N2035/1086—Cylindrical, e.g. variable angle
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1009—Characterised by arrangements for controlling the aspiration or dispense of liquids
    • G01N35/1011—Control of the position or alignment of the transfer device
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1065—Multiple transfer devices
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1065—Multiple transfer devices
    • G01N35/1074—Multiple transfer devices arranged in a two-dimensional array
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/2575—Volumetric liquid transfer
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/25875—Gaseous sample or with change of physical state

Landscapes

  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nanotechnology (AREA)
  • Organic Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pathology (AREA)
  • Materials Engineering (AREA)
  • Health & Medical Sciences (AREA)
  • Condensed Matter Physics & Semiconductors (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Composite Materials (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)
  • Chemical And Physical Treatments For Wood And The Like (AREA)
  • Seeds, Soups, And Other Foods (AREA)
AT01937586T 2001-02-01 2001-05-18 Vorrichtung zur herstellung von mikromatrizen wobei die vorrichtung in inkrementellen etappen mechanisch eingestellt wird ATE394162T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US09/775,249 US6613284B2 (en) 2001-02-01 2001-02-01 Microarrayer

Publications (1)

Publication Number Publication Date
ATE394162T1 true ATE394162T1 (de) 2008-05-15

Family

ID=25103800

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01937586T ATE394162T1 (de) 2001-02-01 2001-05-18 Vorrichtung zur herstellung von mikromatrizen wobei die vorrichtung in inkrementellen etappen mechanisch eingestellt wird

Country Status (6)

Country Link
US (2) US6613284B2 (de)
EP (1) EP1363737B1 (de)
AT (1) ATE394162T1 (de)
DE (1) DE60133937D1 (de)
TW (1) TW505784B (de)
WO (1) WO2002060583A1 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030166263A1 (en) * 2002-12-30 2003-09-04 Haushalter Robert C. Microfabricated spotting apparatus for producing low cost microarrays
DE202004007120U1 (de) * 2004-05-03 2005-09-29 Zeitz, Patric, Dr. Druckkopfsystem für Microarray Drucker
WO2006094049A2 (en) * 2005-03-01 2006-09-08 Parallel Synthesis Technologies, Inc. Polymeric fluid transfer and printing devices
US8360554B2 (en) 2007-07-19 2013-01-29 Xerox Corporation Modular encoder
US9047545B2 (en) * 2007-11-13 2015-06-02 Medica Corporation Modular chemistry analyzer
US9289868B2 (en) * 2012-04-24 2016-03-22 Scott J. Gray Adjustable angle workpiece positioning disc
CN102778371A (zh) * 2012-07-06 2012-11-14 清华大学 含三维预置缺陷的脆性介质试样的制作方法
US20140065036A1 (en) * 2012-09-05 2014-03-06 Matthew Orcutt Tray Support for Chromatographic Equipment
EP3107656A4 (de) * 2014-02-21 2017-11-08 Shilps Sciences Private Limited Mikrotröpfchenarray zum mehrfach-screening einer probe

Family Cites Families (52)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2012859A (en) * 1933-10-30 1935-08-27 William J Vocke Indexing device for dividing heads
US2369425A (en) * 1943-04-05 1945-02-13 Gen Mills Inc Work holder and indexing means
US2385396A (en) * 1944-05-29 1945-09-25 Francis P Baum Indexing unit
US2589554A (en) * 1948-06-11 1952-03-18 Jennings B Killian Saw guide for portable power-driven hand-operated circular saws
US2535490A (en) * 1949-05-20 1950-12-26 Melvin H Emrick Automatic electric index fixture
US2718062A (en) * 1952-05-06 1955-09-20 William E Cross Protractor structure
CH350529A (de) * 1955-12-15 1960-11-30 Koepings Mekaniska Verkstads A Vorrichtung zur Erzielung einer genauen Teilung oder Winkeleinstellung
US3568735A (en) * 1968-06-26 1971-03-09 Cooke Eng Co Laboratory microtitration dispensing apparatus
US3541694A (en) * 1969-07-07 1970-11-24 Walter F Schafer Dividing head
US3638527A (en) * 1969-10-20 1972-02-01 Wood Industries Inc Indexing fixture
US3687175A (en) * 1970-11-09 1972-08-29 Victor Stephen Babey Apparatus for filling thin tubular containers with a liquid
US3901658A (en) * 1974-07-30 1975-08-26 Us Energy Whole blood analysis rotor assembly having removable cellular sedimentation bowl
US3965936A (en) * 1974-11-20 1976-06-29 Price Pfister Brass Mfg. Co. Single handled mixing valve
JPS5821566A (ja) * 1981-07-31 1983-02-08 Fuji Photo Film Co Ltd インキユベ−タ
US4507977A (en) * 1981-10-19 1985-04-02 Coulter Electronics, Inc. Liquid metering and transfer valve assembly
CH674580A5 (de) * 1983-10-06 1990-06-15 Contraves Ag
US4702889A (en) * 1986-01-16 1987-10-27 Coulter Electronics Inc. Liquid sampling valve
US4690801A (en) * 1986-06-03 1987-09-01 Allelix Inc. Device for performing enzyme immunoassays
US4847205A (en) * 1987-04-08 1989-07-11 Martin Marietta Energy Systems, Inc. Device and method for automated separation of a sample of whole blood into aliquots
US5342517A (en) * 1987-10-02 1994-08-30 Kopf Henry B Filtration cassette article, and filter comprising same
EP0311440B1 (de) * 1987-10-09 1992-06-24 Seiko Instruments Inc. Gerät zum Durchführen einer Flüssigkeitsreaktion
US5002735A (en) * 1988-07-12 1991-03-26 Mark T. Alberhasky Tissue analysis device
FR2634893B1 (fr) * 1988-07-28 1990-09-14 Guigan Jean Laboratoire miniature pour la realisation d'analyses biologiques par reaction chimique a partir d'un echantillon de sang
DE68925602T2 (de) * 1988-08-02 1996-11-14 Abbott Lab Verfahren und Vorrichtung zum Erzeugen von Eichdaten für die Analyse
JPH0289311U (de) * 1988-12-28 1990-07-16
US4948565A (en) * 1989-04-25 1990-08-14 Fisher Scientific Company Analytical system
US5100626A (en) * 1990-05-24 1992-03-31 Levin Andrew E Binding assay device with removable cassette and manifold
US5122284A (en) * 1990-06-04 1992-06-16 Abaxis, Inc. Apparatus and method for optically analyzing biological fluids
US5061381A (en) * 1990-06-04 1991-10-29 Abaxis, Inc. Apparatus and method for separating cells from biological fluids
US5057684A (en) * 1990-08-30 1991-10-15 Robbins & Myers/Electro-Craft, A Wholly Owned Sub. Of Robbins & Myers, Inc. Unitary aligning and gapping apparatus for modular optical shaft encoder
US5324481A (en) * 1991-06-03 1994-06-28 Abbott Laboratories Carousel for assay specimen carrier
FR2679660B1 (fr) * 1991-07-22 1993-11-12 Pasteur Diagnostics Procede et dispositif magnetique d'analyse immunologique sur phase solide.
US5188733A (en) * 1992-02-26 1993-02-23 Trustees Of Boston University Apparatus and process for effecting sequential peptide syntheses
US6380751B2 (en) * 1992-06-11 2002-04-30 Cascade Microtech, Inc. Wafer probe station having environment control enclosure
US5290521A (en) * 1992-09-04 1994-03-01 Destefano Jr Albert M Lab-top work station
GB2310006B (en) * 1995-12-01 2000-01-12 Genetix Ltd Pneumatic actuator
US5708496A (en) * 1996-03-11 1998-01-13 Renco Encoders, Inc. Modular optical shaft encoder having a slide gap centering mechanism and method of use
US6399023B1 (en) * 1996-04-16 2002-06-04 Caliper Technologies Corp. Analytical system and method
KR100215926B1 (ko) * 1996-05-17 1999-08-16 류정열 엔코더와 포텐시어미터의 결합된 방식을 가지는 자동차의 조향각도센서
JP3032159B2 (ja) * 1996-09-24 2000-04-10 株式会社日立製作所 分析システム
DE69835181T2 (de) * 1997-04-09 2006-11-23 Hitachi, Ltd. System zur automatischen Probenanalyse und Verfahren zu dessen Betrieb
CH691719A5 (fr) * 1997-04-11 2001-09-14 Etel Sa Table X-Y pour déplacer une charge, telle qu'un outil, selon deux directions perpendiculaires.
US5961925A (en) * 1997-09-22 1999-10-05 Bristol-Myers Squibb Company Apparatus for synthesis of multiple organic compounds with pinch valve block
US6274088B1 (en) * 1998-04-06 2001-08-14 Pharmacopeia, Inc. Methods and apparatus for high throughput plate to plate or plate to membrane transfer
AU4861099A (en) * 1998-07-07 2000-01-24 Cartesian Technologies, Inc. Tip design and random access array for microfluidic transfer
US6432719B1 (en) * 1999-02-16 2002-08-13 Pe Corporation (Ny) Matrix storage and dispensing system
US6399394B1 (en) * 1999-06-30 2002-06-04 Agilent Technologies, Inc. Testing multiple fluid samples with multiple biopolymer arrays
SG89335A1 (en) * 1999-07-09 2002-06-18 Molex Inc Socket for pin grid array package
US6326212B1 (en) * 1999-10-12 2001-12-04 Arden Systems, Inc. Membrane dispensing head apparatus and method for dispensing liquid
US6186930B1 (en) * 2000-05-01 2001-02-13 David P. Ignaczak Push-up trainer
JP4240774B2 (ja) * 2000-07-17 2009-03-18 株式会社東海理化電機製作所 回転角度検出装置及び回転角度検出方法
US6328508B1 (en) * 2000-08-02 2001-12-11 Arnold R. Jines Indexing device for a machine tool

Also Published As

Publication number Publication date
WO2002060583A8 (en) 2003-11-20
US20020102716A1 (en) 2002-08-01
US20030078690A1 (en) 2003-04-24
TW505784B (en) 2002-10-11
EP1363737A4 (de) 2007-01-17
WO2002060583A1 (en) 2002-08-08
DE60133937D1 (de) 2008-06-19
EP1363737A1 (de) 2003-11-26
EP1363737B1 (de) 2008-05-07
US6692701B2 (en) 2004-02-17
US6613284B2 (en) 2003-09-02

Similar Documents

Publication Publication Date Title
ATE408455T1 (de) Arrayplatten und verfahren zur herstellung von arrayplatten
DK676288D0 (da) Dokument og fremgangsmaade til fremstilling af samme
BR9007483A (pt) Substrato e metodo para cultura de fungos,incluindo shiitake(lentinus edodes)
DE69016753D1 (de) Vorrichtung, die sich an einer Fläche entlang bewegen kann.
DE50210526D1 (de) Verfahren zur herstellung eines aus mehreren schichten bestehenden dreidimensionalen bauteils
ATE394162T1 (de) Vorrichtung zur herstellung von mikromatrizen wobei die vorrichtung in inkrementellen etappen mechanisch eingestellt wird
SE0001931D0 (sv) Metod vid tillverkning av en mall, samt mallen tillverkad därav
ATE467231T1 (de) Verfahren zur herstellung von vias in silizium carbid und dessen bauelementen und schaltkreise
DE69107690D1 (de) Dünnfilmelektrode für Vorrichtungen und elektrolumineszente Vorrichtung damit und Verfahren zur Herstellung derselben.
DE68911661D1 (de) Vorrichtung, die einen elektrischen Steckverbinder bildet.
ATE309760T1 (de) Vorrichtung zur bildung von löchern und einführhülsen in einer in einem dentalbefestigungsteil enthaltenen einheit
BE903474A (nl) Vacuumvorm
DE60117699D1 (de) Analyseverfahren durch spezifisches binden und vorrichtung, die das verfahren einsetzt
EP2260970A3 (de) Verfahren zur Herstellung von mikrostrukturierten Lamellen und Vorrichtung
DE50114469D1 (de) Ultraphobes flächengebilde mit einer vielzahl von hydrophilen bereichen
EP1385098A3 (de) Simulation von Datentypen in einer relationalen Datenbank
EP1724018A3 (de) Substrat und Vorrichtung für einen Bioassay sowie Verfahren zur Substratherstellung
DE59009031D1 (de) Vorrichtung zur reduzierung von leerlaufverlusten bei hydrodynamischen bremsen.
DE60100747D1 (de) Elektromechanische vorrichtung zum testen von ic-chips, die für die erste und die zweite aneinander gepresste substratgruppe benutzt werden
DE59912665D1 (de) Verfahren zur Herstellung von Leistungshalbleiterbauelementen
ATE330792T1 (de) Verfahren und vorrichtung zur herstellung eines tragbaren datenträgers
DE69914902D1 (de) Verfahren zur herstellung einer ic-karte und eine solche hergestellte karte
DE69414331D1 (de) Verfahren zur herstellung einer karte, die mindestens einen elektronischen baustein enthält
SE0301236D0 (sv) Method of manufacturing a nanoscale conductive device
DE59001454D1 (de) Vorrichtung fuer die elektrische funktionspruefung von verdrahtungsfeldern, inbesondere von leiterplatten.

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties