ATE39252T1 - Quartaere salze von dibenz(1,4)diazepinon, pyrido(1,4)benzodiazepinon, pyrido(1,5)benzodiazepinonderivate und ihre pharmakologische wirkung. - Google Patents

Quartaere salze von dibenz(1,4)diazepinon, pyrido(1,4)benzodiazepinon, pyrido(1,5)benzodiazepinonderivate und ihre pharmakologische wirkung.

Info

Publication number
ATE39252T1
ATE39252T1 AT84105155T AT84105155T ATE39252T1 AT E39252 T1 ATE39252 T1 AT E39252T1 AT 84105155 T AT84105155 T AT 84105155T AT 84105155 T AT84105155 T AT 84105155T AT E39252 T1 ATE39252 T1 AT E39252T1
Authority
AT
Austria
Prior art keywords
pyrido
benzodiazepinone
salts
diazepinone
dibenz
Prior art date
Application number
AT84105155T
Other languages
English (en)
Inventor
Roberto Giani
Ettore Parini
Giancarlo Tonon
Original Assignee
Dompe Farmaceutici Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dompe Farmaceutici Spa filed Critical Dompe Farmaceutici Spa
Application granted granted Critical
Publication of ATE39252T1 publication Critical patent/ATE39252T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/38—[b, e]- or [b, f]-condensed with six-membered rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
AT84105155T 1983-05-17 1984-05-07 Quartaere salze von dibenz(1,4)diazepinon, pyrido(1,4)benzodiazepinon, pyrido(1,5)benzodiazepinonderivate und ihre pharmakologische wirkung. ATE39252T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT8321135A IT1212743B (it) 1983-05-17 1983-05-17 Sali quaternari di derivati di benzo[ 1,4 ]diazepinonici,pirido [1,4]benzodiazepinonici,prido [1,5]benzodiazepinonici e loro atti vita' farmacologica
EP84105155A EP0126366B1 (de) 1983-05-17 1984-05-07 Quartäre Salze von Dibenz(1,4)diazepinon, Pyrido(1,4)benzodiazepinon, Pyrido(1,5)benzodiazepinonderivate und ihre pharmakologische Wirkung

Publications (1)

Publication Number Publication Date
ATE39252T1 true ATE39252T1 (de) 1988-12-15

Family

ID=11177263

Family Applications (1)

Application Number Title Priority Date Filing Date
AT84105155T ATE39252T1 (de) 1983-05-17 1984-05-07 Quartaere salze von dibenz(1,4)diazepinon, pyrido(1,4)benzodiazepinon, pyrido(1,5)benzodiazepinonderivate und ihre pharmakologische wirkung.

Country Status (6)

Country Link
US (1) US4594190A (de)
EP (1) EP0126366B1 (de)
JP (2) JPS6016977A (de)
AT (1) ATE39252T1 (de)
DE (1) DE3475619D1 (de)
IT (1) IT1212743B (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0213293B1 (de) * 1985-06-27 1992-01-02 Dr. Karl Thomae GmbH In 11-Stellung substituierte 5,11-Dihydro-6H-pyrido-[2,3-b][1,4]benzodiazepin-6-one, Verfahren zur ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
IT8721978A0 (it) * 1987-09-21 1987-09-21 Angeli Inst Spa Nuovi derivati ammidinici triciclici.
US4985420A (en) * 1987-12-10 1991-01-15 Duphar International Research B.V. 1,7-annelated indolecarboxylic acid esters and -amides
DE3820347A1 (de) * 1988-06-15 1989-12-21 Thomae Gmbh Dr K Verwendung von in 11-stellung substituierten 5,11-dihydro-6h-pyrido(2,3-b) (1,4)benzodiazepin-6-onen zur behandlung von bradycardien und bradyarrhythmien in der human- und veterinaermedizin
PT2445502T (pt) 2009-06-25 2017-09-22 Alkermes Pharma Ireland Ltd Compostos heterocíclicos para o tratamento de distúrbios neurológicos e psicológicos
AU2010266040B2 (en) 2009-06-25 2015-01-15 Alkermes Pharma Ireland Limited Prodrugs of NH-acidic compounds
CA2802733C (en) 2010-06-24 2017-11-21 Alkermes Pharma Ireland Limited Prodrugs of nh-acidic compounds: ester, carbonate, carbamate and phosphonate derivatives
RU2627469C2 (ru) 2011-03-18 2017-08-08 Алкермес Фарма Айэленд Лимитед Фармацевтические композиции, содержащие водонерастворимое антипсихотическое средство и сложные эфиры сорбита
EP2790734B1 (de) 2011-12-15 2019-02-20 Alkermes Pharma Ireland Limited Prodrugs von sekundären aminverbindungen
NZ630428A (en) 2012-03-19 2017-02-24 Alkermes Pharma Ireland Ltd Pharmaceutical compositions comprising benzyl alcohol
AU2013235523B9 (en) 2012-03-19 2018-01-04 Alkermes Pharma Ireland Limited Pharmaceutical compositions comprising glycerol esters
US10004807B2 (en) 2012-03-19 2018-06-26 Alkermes Pharma Ireland Limited Pharmaceutical compositions comprising fatty acid esters
NZ748572A (en) 2012-09-19 2020-07-31 Alkermes Pharma Ireland Ltd Pharmaceutical compositions having improved storage stability
AU2015231278B2 (en) 2014-03-20 2020-01-23 Alkermes Pharma Ireland Limited Aripiprazole formulations having increased injection speeds
AU2019230014A1 (en) 2018-03-05 2020-09-17 Alkermes Pharma Ireland Limited Aripiprazole dosing strategy

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1071815A (en) * 1964-10-19 1967-06-14 Boots Pure Drug Co Ltd Phenothiazine derivatives
FR1505795A (fr) * 1965-12-17 1967-12-15 Thomae Gmbh Dr K Procédé pour fabriquer de nouvelles 11h-pyrido[2, 3-b][1, 5]benzodiazépine-5(6h)-ones substituées en position 11
FI49509C (fi) * 1968-08-20 1975-07-10 Thomae Gmbh Dr K Menetelmä farmakologisesti vaikuttavien 5-asemaan substituoitujen 5,10 -dihydro-11H-dibentso/b,e//1,4/deatsepiini-11-onien ja niiden suolojen valmistamiseksi.
US3727046A (en) * 1971-01-04 1973-04-10 D Woods Vehicle travel speed control and monitoring method and apparatus
US3966736A (en) * 1975-04-07 1976-06-29 The Upjohn Company 2,9-Dihydro-3H-pyrido[3,2-c]-s-triazolo[4,3-a][1,5]-benzodiazepin-3-ones
US4210648A (en) * 1977-05-31 1980-07-01 Boehringer Ingelheim Gmbh II-Aminoacyl-5,11-dihydro-6H-pyrido(2,3-B) (1,4)benzodiazepin-6-ones and salts thereof
DE3028001A1 (de) * 1980-07-24 1982-02-18 Dr. Karl Thomae Gmbh, 7950 Biberach Neue, in 5-stellung substituierte 5,10-dihydro-11h-dibenzo (b,e)(1,4) diazepin-11-one, verfahren zu ihrer herstellung und diese verbindung enthaltende arzneimittel
IT1194766B (it) * 1981-03-10 1988-09-28 Crc Ricerca Chim Processo per la preparazione di 11-(2'-sostituito)-acetil-5,11-diidro-6h-pirido-(2,3-b)(1,4)-benzodiazepin-6-oni
IT1212742B (it) * 1983-05-17 1989-11-30 Dompe Farmaceutici Spa Derivati dibenzo [1,4]diazepinonici pirido [1,4] benzodiazepinonici,pirido [1,5] benzodiazepinonici e loro attivita' farmacologica

Also Published As

Publication number Publication date
JPH01193225A (ja) 1989-08-03
US4594190A (en) 1986-06-10
DE3475619D1 (en) 1989-01-19
IT1212743B (it) 1989-11-30
EP0126366A3 (en) 1985-07-24
EP0126366A2 (de) 1984-11-28
JPS6016977A (ja) 1985-01-28
EP0126366B1 (de) 1988-12-14
IT8321135A0 (it) 1983-05-17

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee