ATE387194T1 - USING AN IBAT INHIBITOR TO TREAT OR PREVENT CONSTITUTION - Google Patents

USING AN IBAT INHIBITOR TO TREAT OR PREVENT CONSTITUTION

Info

Publication number
ATE387194T1
ATE387194T1 AT04725081T AT04725081T ATE387194T1 AT E387194 T1 ATE387194 T1 AT E387194T1 AT 04725081 T AT04725081 T AT 04725081T AT 04725081 T AT04725081 T AT 04725081T AT E387194 T1 ATE387194 T1 AT E387194T1
Authority
AT
Austria
Prior art keywords
treat
ibat inhibitor
constitution
prevent
prevent constitution
Prior art date
Application number
AT04725081T
Other languages
German (de)
Inventor
Hasse R Abrahamsson
Per-Goran Gillberg
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9956272&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE387194(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Application granted granted Critical
Publication of ATE387194T1 publication Critical patent/ATE387194T1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/554—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one sulfur as ring hetero atoms, e.g. clothiapine, diltiazem
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/10—Laxatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
AT04725081T 2003-04-05 2004-04-01 USING AN IBAT INHIBITOR TO TREAT OR PREVENT CONSTITUTION ATE387194T1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0307918.3A GB0307918D0 (en) 2003-04-05 2003-04-05 Therapeutic use

Publications (1)

Publication Number Publication Date
ATE387194T1 true ATE387194T1 (en) 2008-03-15

Family

ID=9956272

Family Applications (2)

Application Number Title Priority Date Filing Date
AT07023058T ATE513550T1 (en) 2003-04-05 2004-04-01 USING AN IBAT INHIBITOR TO TREAT OR PREVENT CONSTITUTION
AT04725081T ATE387194T1 (en) 2003-04-05 2004-04-01 USING AN IBAT INHIBITOR TO TREAT OR PREVENT CONSTITUTION

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT07023058T ATE513550T1 (en) 2003-04-05 2004-04-01 USING AN IBAT INHIBITOR TO TREAT OR PREVENT CONSTITUTION

Country Status (33)

Country Link
US (1) US7514421B2 (en)
EP (2) EP1610770B1 (en)
JP (2) JP4870552B2 (en)
KR (1) KR101321577B1 (en)
CN (1) CN100366241C (en)
AR (1) AR043985A1 (en)
AT (2) ATE513550T1 (en)
AU (1) AU2004228731B2 (en)
BR (1) BRPI0408858A (en)
CA (1) CA2520109C (en)
CO (1) CO5640076A2 (en)
CY (2) CY1107424T1 (en)
DE (1) DE602004012079T2 (en)
DK (2) DK1610770T3 (en)
ES (2) ES2368350T3 (en)
GB (1) GB0307918D0 (en)
HK (1) HK1085666A1 (en)
IL (1) IL170913A (en)
IS (1) IS8113A (en)
MX (1) MXPA05010706A (en)
MY (1) MY137757A (en)
NO (1) NO335140B1 (en)
NZ (1) NZ542835A (en)
PL (2) PL1610770T3 (en)
PT (2) PT1610770E (en)
RU (2) RU2342928C2 (en)
SA (1) SA04250066B1 (en)
SI (2) SI1894564T1 (en)
TW (1) TWI338577B (en)
UA (1) UA84141C2 (en)
UY (1) UY28258A1 (en)
WO (1) WO2004089350A1 (en)
ZA (1) ZA200507996B (en)

Families Citing this family (51)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EG26979A (en) 2000-12-21 2015-03-01 Astrazeneca Ab Chemical compounds
GB0121337D0 (en) 2001-09-04 2001-10-24 Astrazeneca Ab Chemical compounds
GB0121621D0 (en) 2001-09-07 2001-10-31 Astrazeneca Ab Chemical compounds
GB0121622D0 (en) 2001-09-07 2001-10-31 Astrazeneca Ab Chemical compounds
TWI331143B (en) 2001-09-08 2010-10-01 Astrazeneca Uk Ltd Benzothiadiazepine derivatives, process for preparing them, and pharmaceutical composition comprising them
GB0209467D0 (en) 2002-04-25 2002-06-05 Astrazeneca Ab Chemical compounds
GB0213669D0 (en) 2002-06-14 2002-07-24 Astrazeneca Ab Chemical compounds
GB0304194D0 (en) * 2003-02-25 2003-03-26 Astrazeneca Ab Chemical compounds
GB0307918D0 (en) * 2003-04-05 2003-05-14 Astrazeneca Ab Therapeutic use
AR057828A1 (en) * 2005-09-29 2007-12-19 Astrazeneca Ab COMPOUNDS DERIVED FROM AZETIDINE, ITS PREPARATION AND PHARMACEUTICAL COMPOSITION
EP2125711B1 (en) * 2007-03-08 2013-11-06 Albireo Ab 3-phenylpropionic acid derivatives and their use in the treatment of inflammatory bowel disease
CN102316872B (en) * 2008-11-26 2016-12-21 萨蒂奥根制药公司 Treatment obesity and the bile acid recycling inhibitors of diabetes
EP3593802A3 (en) * 2010-05-26 2020-03-25 Satiogen Pharmaceuticals, Inc. Bile acid recycling inhibitors and satiogens for treatment of diabetes, obesity, and inflammatory gastrointestinal conditions
AU2011326871B2 (en) 2010-11-08 2015-02-12 Albireo Ab IBAT inhibitors for the treatment of liver diseases
SG11201401816SA (en) 2011-10-28 2014-05-29 Lumena Pharmaceuticals Inc Bile acid recycling inhibitors for treatment of hypercholemia and cholestatic liver disease
EA201891154A1 (en) 2011-10-28 2019-02-28 ЛУМЕНА ФАРМАСЬЮТИКАЛС ЭлЭлСи INHIBITORS OF BILIC ACID RECYCLING IN THE TREATMENT OF CHOLESTATIC DISEASES OF THE LIVER IN CHILDREN
KR20160002773A (en) 2013-03-15 2016-01-08 루메나 파마수티컬즈, 인코포레이티드 Bile acid recycling inhibitors for treatment of primary sclerosing cholangitis and inflammatory bowel disease
MX2015013196A (en) 2013-03-15 2016-04-15 Lumena Pharmaceuticals Inc Bile acid recycling inhibitors for treatment of barrett's esophagus and gastroesophageal reflux disease.
JO3301B1 (en) 2013-04-26 2018-09-16 Albireo Ab Crystal modifications of elobixibat
KR101420315B1 (en) 2014-03-19 2014-07-17 남봉길 Pharmaceutical liquid composition
JP6581082B2 (en) 2014-06-25 2019-09-25 Ｅａファーマ株式会社 Solid preparation and method for stabilizing the same
JP6751020B2 (en) 2014-06-25 2020-09-02 Ｅａファーマ株式会社 Solid preparation and method for preventing or reducing coloration thereof
EP3012252A1 (en) 2014-10-24 2016-04-27 Ferring BV Crystal modifications of elobixibat
CN109310774A (en) 2015-08-17 2019-02-05 费林股份公司 Containing can sulfate and magnesium citrate liquid preparation
US10786529B2 (en) 2016-02-09 2020-09-29 Albireo Ab Oral cholestyramine formulation and use thereof
US10441605B2 (en) 2016-02-09 2019-10-15 Albireo Ab Oral cholestyramine formulation and use thereof
US10441604B2 (en) 2016-02-09 2019-10-15 Albireo Ab Cholestyramine pellets and methods for preparation thereof
FI3643718T3 (en) 2017-06-20 2023-11-01 Takeda Pharmaceuticals Co Heterocyclic compound and its use as positive allosteric modulator of the cholinergic muscarinic m1 receptor.
CN111032019B (en) 2017-08-09 2022-07-05 阿尔比里奥公司 Cholestyramine granules, oral cholestyramine preparation and application thereof
CA3091338A1 (en) 2018-03-09 2019-09-12 Elobix Ab Process for the preparation of elobixibat
US10428109B1 (en) 2018-03-09 2019-10-01 Elobix Ab Process for the preparation of 1,5-benzothiazepine compounds
US10793534B2 (en) 2018-06-05 2020-10-06 Albireo Ab Benzothia(di)azepine compounds and their use as bile acid modulators
ES2942443T3 (en) 2018-06-05 2023-06-01 Albireo Ab Benzothia(di)azepine compounds and their use as bile acid modulators
US11801226B2 (en) 2018-06-20 2023-10-31 Albireo Ab Pharmaceutical formulation of odevixibat
TWI823954B (en) 2018-06-20 2023-12-01 瑞典商艾爾比瑞歐公司 Crystal modifications of odevixibat
US10722457B2 (en) 2018-08-09 2020-07-28 Albireo Ab Oral cholestyramine formulation and use thereof
US11549878B2 (en) 2018-08-09 2023-01-10 Albireo Ab In vitro method for determining the adsorbing capacity of an insoluble adsorbant
US11007142B2 (en) 2018-08-09 2021-05-18 Albireo Ab Oral cholestyramine formulation and use thereof
US10975045B2 (en) 2019-02-06 2021-04-13 Aibireo AB Benzothiazepine compounds and their use as bile acid modulators
US10941127B2 (en) 2019-02-06 2021-03-09 Albireo Ab Benzothiadiazepine compounds and their use as bile acid modulators
BR112021015809A2 (en) 2019-02-12 2022-01-18 Mirum Pharmaceuticals Inc Genotype and dose dependent response to an asbti in patients with bile salt export pump deficiency
JP2023504643A (en) 2019-12-04 2023-02-06 アルビレオ・アクチボラグ Benzothia(di)azepine compounds and their use as bile acid modulators
US11014898B1 (en) 2020-12-04 2021-05-25 Albireo Ab Benzothiazepine compounds and their use as bile acid modulators
MX2022006731A (en) 2019-12-04 2022-06-09 Albireo Ab Benzothia(di)azepine compounds and their use as bile acid modulators.
JP2023504647A (en) 2019-12-04 2023-02-06 アルビレオ・アクチボラグ Benzothia(di)azepine compounds and their use as bile acid modulators
JP2023504644A (en) 2019-12-04 2023-02-06 アルビレオ・アクチボラグ Benzothiadiazepine compounds and their use as bile acid modulators
CN116157389A (en) 2020-08-03 2023-05-23 阿尔比里奥公司 Benzothiazepine compounds and their use as bile acid modulators
KR20230106651A (en) 2020-11-12 2023-07-13 알비레오 에이비 Odevixivat for the treatment of progressive familial intrahepatic cholestasis (PFIC)
CA3198216A1 (en) 2020-12-04 2022-06-09 Albireo Ab Benzothia(di)azepine compounds and their use as bile acid modulators
WO2022166680A1 (en) * 2021-06-25 2022-08-11 苏州科睿思制药有限公司 Crystal form of odevixibat, and preparation method and use therefor
AU2023255249A1 (en) 2022-04-22 2024-10-17 Albireo Ab Subcutaneous administration of an asbt inhibitor

Family Cites Families (68)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO170760C (en) 1985-01-10 1992-12-02 Tanabe Seiyaku Co ANALOGY PROCEDURE FOR THE PREPARATION OF THERAPEUTICALLY ACTIVE NAPHENSE DERIVATIVES
JPS6310746A (en) 1986-07-01 1988-01-18 Tanabe Seiyaku Co Ltd Naphthalene derivative
US4900757A (en) 1988-12-08 1990-02-13 Merrell Dow Pharmaceuticals Inc. Hypocholesterolemic and antiatherosclerotic uses of bix(3,5-di-tertiary-butyl-4-hydroxyphenylthio)methane
DE3930696A1 (en) 1989-09-14 1991-03-28 Hoechst Ag GALLENSAEUREDERIVATE, METHOD FOR THE PRODUCTION THEREOF, USE AS MEDICAMENT
ATE144988T1 (en) 1990-12-06 1996-11-15 Hoechst Ag BALE ACID DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND USE OF THIS COMPOUND AS A MEDICINAL PRODUCT
ES2129733T3 (en) 1991-10-17 1999-06-16 Shionogi & Co PROCEDURE FOR THE PREPARATION OF LIGNIN ANALOGS AND STARTING PRODUCTS FOR THESE.
FI108451B (en) 1991-12-20 2002-01-31 Hoechst Ag A process for preparing polymeric and oligomeric bile acid derivatives
JPH05186357A (en) * 1991-12-31 1993-07-27 Shigeo Ochi Absorption-inhibitory means for digested product of food/ beverage
GEP20001968B (en) * 1992-01-21 2000-03-05 Glaxo Spa Arilthio Compounds as Antibacterial and Antiviral Agents
GB9203347D0 (en) * 1992-02-17 1992-04-01 Wellcome Found Hypolipidaemic compounds
EP0573848B1 (en) 1992-06-12 1997-12-03 Hoechst Aktiengesellschaft Bile-acid derivatives, a process for their production and their use as medicines
IL108634A0 (en) 1993-02-15 1994-05-30 Wellcome Found Hypolipidaemic heterocyclic compounds, their prepatation and pharmaceutical compositions containing them
ZA941003B (en) 1993-02-15 1995-08-14 Wellcome Found Hypolipidaemic compounds
EP0646570B1 (en) 1993-04-16 1998-06-24 Shionogi & Co., Ltd. Process for producing lignan compound
TW289021B (en) 1993-05-08 1996-10-21 Hoechst Ag
TW289020B (en) 1993-05-08 1996-10-21 Hoechst Sktiengesellschaft
EP0624593A3 (en) 1993-05-08 1995-06-07 Hoechst Ag Bile acid derivates, a method for their production and their use as medicines.
ZA956647B (en) 1994-08-10 1997-02-10 Wellcome Found Hypolipidaemic compounds.
WO1996008484A1 (en) 1994-09-13 1996-03-21 Monsanto Company Novel benzothiepines having activity as inhibitors of ileal bile acid transport and taurocholate uptake
US5994391A (en) 1994-09-13 1999-11-30 G.D. Searle And Company Benzothiepines having activity as inhibitors of ileal bile acid transport and taurocholate uptake
GB9423172D0 (en) 1994-11-17 1995-01-04 Wellcom Foundation The Limited Hypolipidemic benzothiazepines
CN1110494C (en) 1996-03-11 2003-06-04 G·D·瑟尔公司 Novel benzothiepines having activity as inhibitors of ileal bile acid transport and taurocholate uptake
WO1998007749A1 (en) 1996-08-23 1998-02-26 Human Genome Sciences, Inc. Novel human growth factors
JPH1072371A (en) 1996-08-28 1998-03-17 Sankyo Co Ltd Inhibitor of ileum type bile acid transporter
GB9704208D0 (en) 1997-02-28 1997-04-16 Glaxo Group Ltd Chemical compounds
PL336415A1 (en) 1997-03-11 2000-06-19 Searle & Co Combined therapy employing ileic bile acid transport inhibiting benzothiepins as well as a hmg co-enzyme reductase inhibitors
ES2198613T3 (en) 1997-03-14 2004-02-01 Aventis Pharma Deutschland Gmbh 1,4-BENZOTIAZEPINA-1,1-HYPOLIPIDEMIC DIOXIDES.
ES2223091T3 (en) 1997-04-04 2005-02-16 Aventis Pharma Deutschland Gmbh HYPOLIPIDEMIC PROPANOLAMINE DERIVATIVES.
DE19845402B4 (en) 1998-10-02 2005-04-07 Aventis Pharma Deutschland Gmbh Heterocyclic substituted propanolamine derivatives, process for their preparation, pharmaceutical compositions containing them and their use
AU7552198A (en) 1997-06-11 1998-12-30 Sankyo Company Limited Benzylamine derivatives
AUPO763197A0 (en) * 1997-06-30 1997-07-24 Sigma Pharmaceuticals Pty Ltd Health supplement
WO1999032478A1 (en) 1997-12-19 1999-07-01 G.D. Searle & Co. Method of preparing enantiomerically-enriched tetrahydrobenzothiepine oxides
GB9800428D0 (en) 1998-01-10 1998-03-04 Glaxo Group Ltd Chemical compounds
DE19825804C2 (en) 1998-06-10 2000-08-24 Aventis Pharma Gmbh 1,4-Benzothiepin-1,1-dioxide derivatives, processes for their preparation and medicaments containing these compounds
DE19845406C2 (en) 1998-10-02 2001-10-18 Aventis Pharma Gmbh Substituted 1,3-diaryl-2-pyridin-2-yl-3- (pyridin-2-ylamino) propanol derivatives, process for their preparation, medicaments containing these compounds and their use
DE19845405C2 (en) 1998-10-02 2000-07-13 Aventis Pharma Gmbh Aryl-substituted propanolamine derivatives and their use
DE19845403B4 (en) 1998-10-02 2005-02-10 Aventis Pharma Deutschland Gmbh Propanolamine derivatives linked to bile acids, process for their preparation, pharmaceutical compositions containing them and their use
AU1684400A (en) 1998-12-11 2000-07-03 Sankyo Company Limited Substituted benzylamines
JP2002533415A (en) 1998-12-23 2002-10-08 ジー．ディー．サール エルエルシー Combination of ileal bile acid transport inhibitors and nicotinic acid derivatives for cardiovascular applications
EP1140187B1 (en) 1998-12-23 2003-09-03 G.D. Searle LLC. Combinations of an ibat inhibitor and a mtp inhibitor for cardiovascular indications
CN1342089A (en) 1998-12-23 2002-03-27 G.D.瑟尔有限公司 Combinations of ileal bile acid transport inhibitors and cholestery ester transfer protein inhibitors for cardiovascular disease
BR9916484A (en) 1998-12-23 2002-01-22 Searle Llc Combinations of ileal bile acid transport inhibitors and bile acid sequestering agents in cardiovascular indications
EA200100707A1 (en) 1998-12-23 2001-12-24 Джи.Ди.Сирл Ллс COMBINATIONS OF INHIBITORS OF TRANSPORT OF BILK ACIDS IN THE SUBJECTIVE AND FIBRIN ACID DERIVATIVES FOR THE CARDIOVASCULAR INDICATIONS
EP1155007A2 (en) 1999-02-12 2001-11-21 G.D. Searle LLC 1,2-benzothiazepines for the treatment of hyperlipidemic diseases
DE19916108C1 (en) 1999-04-09 2001-01-11 Aventis Pharma Gmbh 1,4-Benzothiazepine-1,1-dioxide derivatives substituted with sugar residues, process for their preparation and their use
SE9901387D0 (en) 1999-04-19 1999-04-19 Astra Ab New pharmaceutical foromaulations
US6287609B1 (en) * 1999-06-09 2001-09-11 Wisconsin Alumni Research Foundation Unfermented gel fraction from psyllium seed husks
TR200002099A2 (en) 1999-07-22 2001-06-21 Sankyo Company Limited Cyclobutene derivatives, their preparation and therapeutic uses
AU1302301A (en) 1999-11-08 2001-06-06 Sankyo Company Limited Nitrogenous heterocycle derivatives
AU784722B2 (en) 2000-02-18 2006-06-01 Merck & Co., Inc. Aryloxyacetic acids for diabetes and lipid disorders
SE0000772D0 (en) * 2000-03-08 2000-03-08 Astrazeneca Ab Chemical compounds
AU2001247331A1 (en) 2000-03-10 2001-09-24 Pharmacia Corporation Combination therapy for the prophylaxis and treatment of hyperlipidemic conditions and disorders
US6794544B2 (en) 2000-03-10 2004-09-21 Pharmacia Corporation Method for the preparation of tetrahydrobenzothiepines
US20020183307A1 (en) 2000-07-26 2002-12-05 Tremont Samuel J. Novel 1,4-benzothiazephine and 1,5-benzothiazepine compounds as inhibitors of apical sodium co-dependent bile acid transport and taurocholate uptake
SE0003766D0 (en) 2000-10-18 2000-10-18 Astrazeneca Ab Novel formulation
EG26979A (en) 2000-12-21 2015-03-01 Astrazeneca Ab Chemical compounds
WO2002053548A1 (en) 2000-12-27 2002-07-11 Banyu Pharmaceutical Co.,Ltd. Benzothiazepine derivatives
US6506921B1 (en) * 2001-06-29 2003-01-14 Virginia Tech Intellectual Properties, Inc. Amine compounds and curable compositions derived therefrom
GB0121337D0 (en) 2001-09-04 2001-10-24 Astrazeneca Ab Chemical compounds
GB0121622D0 (en) 2001-09-07 2001-10-31 Astrazeneca Ab Chemical compounds
GB0121621D0 (en) 2001-09-07 2001-10-31 Astrazeneca Ab Chemical compounds
TWI331143B (en) * 2001-09-08 2010-10-01 Astrazeneca Uk Ltd Benzothiadiazepine derivatives, process for preparing them, and pharmaceutical composition comprising them
GB0201850D0 (en) * 2002-01-26 2002-03-13 Astrazeneca Ab Therapeutic treatment
GB0209467D0 (en) 2002-04-25 2002-06-05 Astrazeneca Ab Chemical compounds
GB0213669D0 (en) 2002-06-14 2002-07-24 Astrazeneca Ab Chemical compounds
GB0216321D0 (en) 2002-07-13 2002-08-21 Astrazeneca Ab Therapeutic treatment
GB0304194D0 (en) 2003-02-25 2003-03-26 Astrazeneca Ab Chemical compounds
GB0307918D0 (en) * 2003-04-05 2003-05-14 Astrazeneca Ab Therapeutic use

Also Published As

Publication number Publication date
MY137757A (en) 2009-03-31
KR20050121241A (en) 2005-12-26
IL170913A (en) 2010-11-30
DE602004012079D1 (en) 2008-04-10
RU2342928C2 (en) 2009-01-10
ES2368350T3 (en) 2011-11-16
AR043985A1 (en) 2005-08-17
JP2011173925A (en) 2011-09-08
EP1894564A2 (en) 2008-03-05
IS8113A (en) 2005-11-01
UA84141C2 (en) 2008-09-25
CN1771027A (en) 2006-05-10
ES2299832T3 (en) 2008-06-01
PL1894564T3 (en) 2011-11-30
RU2008129204A (en) 2010-01-27
HK1085666A1 (en) 2006-09-01
PT1894564E (en) 2011-07-26
US7514421B2 (en) 2009-04-07
JP4870552B2 (en) 2012-02-08
ATE513550T1 (en) 2011-07-15
BRPI0408858A (en) 2006-04-11
CA2520109A1 (en) 2004-10-21
NZ542835A (en) 2009-01-31
WO2004089350A1 (en) 2004-10-21
TW200505434A (en) 2005-02-16
AU2004228731B2 (en) 2008-02-28
AU2004228731A1 (en) 2004-10-21
CN100366241C (en) 2008-02-06
CO5640076A2 (en) 2006-05-31
EP1610770A1 (en) 2006-01-04
RU2482850C2 (en) 2013-05-27
SI1610770T1 (en) 2008-06-30
CA2520109C (en) 2012-03-20
EP1894564A3 (en) 2009-09-09
EP1610770B1 (en) 2008-02-27
NO335140B1 (en) 2014-09-29
UY28258A1 (en) 2004-11-30
CY1107424T1 (en) 2012-12-19
PL1610770T3 (en) 2008-07-31
JP2006522082A (en) 2006-09-28
SA04250066B1 (en) 2008-09-22
SI1894564T1 (en) 2011-08-31
JP5421326B2 (en) 2014-02-19
NO20054369D0 (en) 2005-09-21
KR101321577B1 (en) 2013-10-25
DK1894564T3 (en) 2011-08-29
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