ATE375389T1 - Verfahren zur diagnose, prognose und behandlung von glaukom und verwandten erkrankungen - Google Patents

Verfahren zur diagnose, prognose und behandlung von glaukom und verwandten erkrankungen

Info

Publication number
ATE375389T1
ATE375389T1 AT98901761T AT98901761T ATE375389T1 AT E375389 T1 ATE375389 T1 AT E375389T1 AT 98901761 T AT98901761 T AT 98901761T AT 98901761 T AT98901761 T AT 98901761T AT E375389 T1 ATE375389 T1 AT E375389T1
Authority
AT
Austria
Prior art keywords
glaucoma
prognosis
diagnosis
treatment
methods
Prior art date
Application number
AT98901761T
Other languages
English (en)
Inventor
Thai Nguyen
Jon Polansky
Pu Chen
Hua Chen
Original Assignee
Univ California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ California filed Critical Univ California
Application granted granted Critical
Publication of ATE375389T1 publication Critical patent/ATE375389T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
AT98901761T 1997-01-28 1998-01-09 Verfahren zur diagnose, prognose und behandlung von glaukom und verwandten erkrankungen ATE375389T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US79115497A 1997-01-28 1997-01-28
US08/938,669 US6171788B1 (en) 1997-01-28 1997-09-26 Methods for the diagnosis, prognosis and treatment of glaucoma and related disorders

Publications (1)

Publication Number Publication Date
ATE375389T1 true ATE375389T1 (de) 2007-10-15

Family

ID=27121110

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98901761T ATE375389T1 (de) 1997-01-28 1998-01-09 Verfahren zur diagnose, prognose und behandlung von glaukom und verwandten erkrankungen

Country Status (10)

Country Link
US (1) US6171788B1 (de)
EP (1) EP1012271B1 (de)
JP (1) JP2001509669A (de)
AT (1) ATE375389T1 (de)
AU (1) AU742405B2 (de)
CA (1) CA2278782C (de)
DE (1) DE69838553T2 (de)
NO (1) NO993653L (de)
NZ (1) NZ336860A (de)
WO (1) WO1998032850A1 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6956103B2 (en) 1994-04-28 2005-10-18 The University Of Iowa Research Foundation Glaucoma therapeutics and diagnostics
US6403307B1 (en) 1997-03-21 2002-06-11 University Of Iowa Research Foundation Glaucoma therapeutics and diagnostics
US6475724B1 (en) * 1997-01-28 2002-11-05 The Regents Of The University Of California Nucleic acids, kits, and methods for the diagnosis, prognosis and treatment of glaucoma and related disorders
US7138511B1 (en) * 1997-01-28 2006-11-21 The Regents Of The University Of California Nucleic acids, kits and methods for the diagnosis, prognosis and treatment of glaucoma and related disorders
US6171788B1 (en) 1997-01-28 2001-01-09 The Regents Of The University Of California Methods for the diagnosis, prognosis and treatment of glaucoma and related disorders
JP2002306165A (ja) * 2000-05-17 2002-10-22 Tsubota:Kk 正常眼圧緑内障を含む開放隅角緑内障の関連遺伝子
US20020168639A1 (en) * 2000-09-22 2002-11-14 Muraca Patrick J. Profile array substrates
US20030119000A1 (en) * 2001-11-05 2003-06-26 Jon Polansky Methods to screen and treat individuals with glaucoma or the propensity to develop glaucoma
US6727354B2 (en) * 2001-12-12 2004-04-27 Quest Diagnostics Investments, Inc. Compositions and methods for TIGR genotyping assays
US20220026445A1 (en) * 2018-12-07 2022-01-27 Georgia Tech Research Corporation Antibodies that bind to natively folded myocilin

Family Cites Families (49)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3887699A (en) 1969-03-24 1975-06-03 Seymour Yolles Biodegradable polymeric article for dispensing drugs
US3773919A (en) 1969-10-23 1973-11-20 Du Pont Polylactide-drug mixtures
JPS57501692A (de) 1980-09-24 1982-09-16
PH19942A (en) 1980-11-18 1986-08-14 Sintex Inc Microencapsulation of water soluble polypeptides
IE52535B1 (en) 1981-02-16 1987-12-09 Ici Plc Continuous release pharmaceutical compositions
US4582788A (en) 1982-01-22 1986-04-15 Cetus Corporation HLA typing method and cDNA probes used therein
DE3381518D1 (de) 1982-01-22 1990-06-07 Cetus Corp Verfahren zur charakterisierung von hla und die darin benutzten cdns-testmittel.
IL71064A (en) 1983-02-28 1989-10-31 Lifecodes Corp Paternity and forensic test involving analysis of dna polymorphic genetic regions
US4617299A (en) 1983-12-19 1986-10-14 Knepper Paul A Method for the prevention of ocular hypertension, treatment of glaucoma and treatment of ocular hypertension
DE3413608A1 (de) 1984-04-11 1985-10-24 Hoechst Ag, 6230 Frankfurt Implantierbare zubereitungen von regulatorischen peptiden mit gesteuerter freisetzung und verfahren zu ihrer herstellung
US4683194A (en) 1984-05-29 1987-07-28 Cetus Corporation Method for detection of polymorphic restriction sites and nucleic acid sequences
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US4757089A (en) 1985-06-14 1988-07-12 Massachusetts Eye And Ear Infirmary Increasing aqueous humor outflow
CA1284931C (en) 1986-03-13 1991-06-18 Henry A. Erlich Process for detecting specific nucleotide variations and genetic polymorphisms present in nucleic acids
GB8606719D0 (en) 1986-03-19 1986-04-23 Lister Preventive Med Genetic probes
DE3612537C1 (de) 1986-04-14 1987-07-16 Dispersa Ag Arzneimittel zur Behandlung von Entzuendungen im Auge
CA1338457C (en) 1986-08-22 1996-07-16 Henry A. Erlich Purified thermostable enzyme
IL86724A (en) 1987-06-19 1995-01-24 Siska Diagnostics Inc Methods and kits for amplification and testing of nucleic acid sequences
EP0359789B1 (de) 1988-01-21 1993-08-04 Genentech, Inc. Verstärkung und nachweis von nukleinsäuresequenzen
US5192535A (en) 1988-02-08 1993-03-09 Insite Vision Incorporated Ophthalmic suspensions
IE63392B1 (en) 1988-02-08 1995-04-19 Insite Vision Inc Ophthalmic suspensions
CA1340807C (en) 1988-02-24 1999-11-02 Lawrence T. Malek Nucleic acid amplification process
US5130238A (en) 1988-06-24 1992-07-14 Cangene Corporation Enhanced nucleic acid amplification process
US5190762A (en) 1988-07-06 1993-03-02 Applied Genetics, Inc. Method of administering proteins to living skin cells
DE68926504T2 (de) 1988-07-20 1996-09-12 David Segev Verfahren zur amplifizierung und zum nachweis von nukleinsäuresequenzen
GB2228086A (en) 1988-11-25 1990-08-15 Ici Plc Characterisation of genomic DNA
KR920700360A (ko) 1989-03-22 1992-02-19 하리크 프리드리히 미끄럼 베어링
US5075217A (en) 1989-04-21 1991-12-24 Marshfield Clinic Length polymorphisms in (dC-dA)n ·(dG-dT)n sequences
WO1990013668A1 (en) 1989-05-05 1990-11-15 Lifecodes Corporation Method for genetic analysis of a nucleic acid sample
AU6521790A (en) 1989-10-13 1991-05-16 Hans Schreier Lipophilic acylpyrazinamide prodrugs
US5124154A (en) 1990-06-12 1992-06-23 Insite Vision Incorporated Aminosteroids for ophthalmic use
US5270052A (en) 1991-04-19 1993-12-14 New England Medical Center Hospitals, Inc. Methods and compositions for treatment of infection by intracellular parasites
US5169766A (en) 1991-06-14 1992-12-08 Life Technologies, Inc. Amplification of nucleic acid molecules
WO1993012234A1 (en) 1991-12-13 1993-06-24 Sri International Antiviral reagents based on rna-binding proteins
JPH08502244A (ja) 1992-08-11 1996-03-12 プレジデント アンド フェローズ オブ ハーバード カレッジ 免疫調節ペプチド
US5420120A (en) 1993-12-17 1995-05-30 Alcon Laboratories, Inc. Anti-inflammatory glucocorticoid compounds for topical ophthalmic use
US5474985A (en) 1993-12-22 1995-12-12 The Regents Of The University Of California Preventing and treating elevated intraocular pressure associated with administered or endogenous steroids using non-steroidal cyclooxygenase inhibitors
US5916778A (en) 1994-04-28 1999-06-29 University Of Iowa Research Foundation Diagnostics based on a glaucoma causing gene
US5925748A (en) 1994-04-28 1999-07-20 The University Of Iowa Research Foundation DNA diagnostics for glaucoma
US5885776A (en) 1997-01-30 1999-03-23 University Of Iowa Research Foundation Glaucoma compositions and therapeutic and diagnositic uses therefor
US5789169A (en) * 1994-11-03 1998-08-04 Regents Of The University Of California Methods for the diagnosis of glaucoma
US5606043A (en) 1994-11-03 1997-02-25 The Regents Of The University Of California Methods for the diagnosis of glaucoma
FR2733251B1 (fr) 1995-04-18 1997-07-04 Inst Nat Sante Rech Med Depistage du glaucome juvenile
US5599535A (en) 1995-06-07 1997-02-04 Regents Of The University Of California Methods for the cyto-protection of the trabecular meshwork
US5674888A (en) 1995-06-07 1997-10-07 University Of California Method for the treatment of a trabecular meshwork whose cells are subject to inhibition of cell division
WO1998020131A1 (en) 1996-11-08 1998-05-14 University Of Iowa Research Foundation Glaucoma-associated protein and corresponding nucleic acid and their therapeutic and diagnostic uses
US6171788B1 (en) 1997-01-28 2001-01-09 The Regents Of The University Of California Methods for the diagnosis, prognosis and treatment of glaucoma and related disorders
CA2216997A1 (en) 1997-09-30 1999-03-30 Jean Morissette Molecular diagnostic of glaucomas associated with chromosomes 1
WO1999016898A1 (en) 1997-09-30 1999-04-08 Universite Laval Molecular diagnostic of glaucomas associated with chromosomes 1, and method of treatment thereof

Also Published As

Publication number Publication date
NO993653L (no) 1999-09-28
EP1012271A1 (de) 2000-06-28
CA2278782A1 (en) 1998-07-30
DE69838553D1 (de) 2007-11-22
DE69838553T2 (de) 2008-07-03
US6171788B1 (en) 2001-01-09
WO1998032850A1 (en) 1998-07-30
AU5820498A (en) 1998-08-18
NO993653D0 (no) 1999-07-27
JP2001509669A (ja) 2001-07-24
AU742405B2 (en) 2002-01-03
CA2278782C (en) 2004-05-25
EP1012271B1 (de) 2007-10-10
NZ336860A (en) 2001-06-29

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