ATE371725T1 - Alkohol-dehydrogenase mit hoher stabilität gegenüber lösungsmittel und temperatur - Google Patents

Alkohol-dehydrogenase mit hoher stabilität gegenüber lösungsmittel und temperatur

Info

Publication number
ATE371725T1
ATE371725T1 AT03709768T AT03709768T ATE371725T1 AT E371725 T1 ATE371725 T1 AT E371725T1 AT 03709768 T AT03709768 T AT 03709768T AT 03709768 T AT03709768 T AT 03709768T AT E371725 T1 ATE371725 T1 AT E371725T1
Authority
AT
Austria
Prior art keywords
alcohol dehydrogenase
solvents
temperature
high stability
biocatalysts
Prior art date
Application number
AT03709768T
Other languages
English (en)
Inventor
Wolfgang Stampfer
Birgit Kosjek
Wolfgang Kroutil
Kurt Faber
Original Assignee
Biocatalytics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biocatalytics Inc filed Critical Biocatalytics Inc
Application granted granted Critical
Publication of ATE371725T1 publication Critical patent/ATE371725T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C12P41/002—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by oxidation/reduction reactions
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Analytical Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
AT03709768T 2002-03-18 2003-03-10 Alkohol-dehydrogenase mit hoher stabilität gegenüber lösungsmittel und temperatur ATE371725T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP02405204 2002-03-18

Publications (1)

Publication Number Publication Date
ATE371725T1 true ATE371725T1 (de) 2007-09-15

Family

ID=27838196

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03709768T ATE371725T1 (de) 2002-03-18 2003-03-10 Alkohol-dehydrogenase mit hoher stabilität gegenüber lösungsmittel und temperatur

Country Status (8)

Country Link
US (1) US7569375B2 (de)
EP (1) EP1485471B1 (de)
JP (1) JP2005520517A (de)
AT (1) ATE371725T1 (de)
AU (1) AU2003214111A1 (de)
CA (1) CA2474905A1 (de)
DE (1) DE60315958D1 (de)
WO (1) WO2003078615A1 (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60315958D1 (de) 2002-03-18 2007-10-11 Biocatalytics Inc Alkohol-dehydrogenase mit hoher stabilität gegenüber lösungsmittel und temperatur
EP1654354A1 (de) 2003-08-11 2006-05-10 Codexis, Inc. Verbesserte ketoreduktase polypeptide und entsprechende polynukleotide
WO2005026338A1 (en) * 2003-09-18 2005-03-24 Ciba Specialty Chemicals Holding Inc. Alcohol dehydrogenases with increased solvent and temperature stability
AT501496B1 (de) * 2005-02-21 2007-03-15 Iep Gmbh Verfahren zur enantioselektiven enzymatischen reduktion von ketoverbindungen
DE102005010804A1 (de) * 2005-03-07 2006-09-14 Basf Ag Verfahren zur Herstellung optisch aktiver Alkohole
AT502395B1 (de) * 2005-07-27 2007-03-15 Iep Gmbh Oxidoreduktasen zur stereoselektiven reduktion von ketoverbindungen
AT502185B1 (de) * 2005-09-23 2007-02-15 Iep Gmbh Verfahren zur enantioselektiven enzymatischen reduktion von ketoverbindungen
AT503017B1 (de) 2005-12-19 2007-07-15 Iep Gmbh Verfahren zur enantioselektiven enzymatischen reduktion von hydroxyketoverbindungen
DE102006009744A1 (de) * 2006-03-02 2007-09-06 Wacker Chemie Ag Herstellung von (S)-2-Butanol durch oxidative Racematspaltung
US8962298B2 (en) * 2006-05-02 2015-02-24 Butamax Advanced Biofuels Llc Recombinant host cell comprising a diol dehydratase
US8828704B2 (en) 2006-05-02 2014-09-09 Butamax Advanced Biofuels Llc Fermentive production of four carbon alcohols
US7659104B2 (en) 2006-05-05 2010-02-09 E.I. Du Pont De Nemours And Company Solvent tolerant microorganisms and methods of isolation
US8426174B2 (en) 2007-05-02 2013-04-23 Butamax(Tm) Advanced Biofuels Llc Method for the production of 2-butanol
DK2262901T3 (en) 2008-03-05 2019-01-21 Genomatica Inc ORGANISMS PRODUCING PRIMARY ALCOHOL
US8188250B2 (en) * 2008-04-28 2012-05-29 Butamax(Tm) Advanced Biofuels Llc Butanol dehydrogenase enzyme from the bacterium Achromobacter xylosoxidans
BRPI0909989A2 (pt) 2008-06-05 2021-06-22 Butamax Advanced Biofuels Llc célula de levedura recombinante e método para a produção de um produto
AU2009296227A1 (en) * 2008-09-29 2010-04-01 Butamax(Tm) Advanced Biofuels Llc Enhanced pyruvate to 2,3-butanediol conversion in lactic acid bacteria
DE102008064575B4 (de) * 2008-12-31 2011-06-01 Barakat, Adil Verfahren zur Herstellung von 1-Hydroxyketon-Verbindungen
WO2010115054A2 (en) 2009-04-01 2010-10-07 Xylofuel, Llc Process to produce organic compounds from synthesis gases
CA2784903A1 (en) 2009-12-29 2011-07-28 Butamax(Tm) Advanced Biofuels Llc Alcohol dehydrogenases (adh) useful for fermentive production of lower alkyl alcohols
EP2963121A1 (de) 2014-07-03 2016-01-06 Basf Se Autarke biokatalytische Redoxaminierung von Alkoholen

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3574682B2 (ja) * 1993-09-24 2004-10-06 ダイセル化学工業株式会社 新規な酵素、該酵素を製造する方法、該酵素をコードするｄｎａ、該ｄｎａを含む形質転換体、該酵素による光学活性アルコール等の製造方法
DE60315958D1 (de) 2002-03-18 2007-10-11 Biocatalytics Inc Alkohol-dehydrogenase mit hoher stabilität gegenüber lösungsmittel und temperatur

Also Published As

Publication number Publication date
CA2474905A1 (en) 2003-09-25
US7569375B2 (en) 2009-08-04
WO2003078615A1 (en) 2003-09-25
AU2003214111A1 (en) 2003-09-29
DE60315958D1 (de) 2007-10-11
US20040157305A1 (en) 2004-08-12
EP1485471A1 (de) 2004-12-15
EP1485471B1 (de) 2007-08-29
JP2005520517A (ja) 2005-07-14

Similar Documents

Publication Publication Date Title
ATE371725T1 (de) Alkohol-dehydrogenase mit hoher stabilität gegenüber lösungsmittel und temperatur
Bertsch et al. A novel route for ethanol oxidation in the acetogenic bacterium Acetobacterium woodii: the acetaldehyde/ethanol dehydrogenase pathway
Bertsch et al. CO metabolism in the acetogen Acetobacterium woodii
DE60142949D1 (de) (r)-2-octanol dehydrogenasen, verfahren zur herstellung dieser enzyme, dna, welche für dieser enzyme kodiert, und verfahren zur herstellung von alkoholen durch anwendung der enzyme
EA201270187A1 (ru) Ферментативное продуцирование этанола, не содержащего глицерин
WO2009112472A3 (en) Selection of organisms capable of fermenting mixed substrates
ATE407138T1 (de) Verfahren zur herstellung interferierender rna- moleküle in säugetierzellen und therapeutische anwendungen solcher moleküle
WO2008102861A1 (ja) Ｌ－アミノ酸の製造法
ATE484518T1 (de) Oxidoreduktase aus pichia capsulata
DE60038886D1 (de) Neue enzyme, welche glycerin entwässern
UA103335C2 (ru) Способ изготовления добавки для ферментативного расщепления микотоксинов, добавка и ее применение
WO2002050289A8 (en) Methods for the production of multimeric proteins, and related compositions
JP2014520564A5 (de)
EA200970226A1 (ru) Термофильные микроорганизмы для производства этанола
WO2006015802A3 (de) Verfahren zur herstellung von primären alkoholen durch reduktion von aldehyden unter verwendung einer alkoholdehydrogenase bei gekoppelter cofaktor-regenerierung
AU2003235980A1 (en) Novel carbonyl reductase, gene thereof and use of the same
RU2001129789A (ru) Способ получения оксида линалоола или содержащих оксид линалоола смесей
ATE491036T1 (de) Herstellung von optisch aktiven alkoholen mit ganzzellenkatalysatoren
WO2008035187A3 (en) Alcohol dehydrogenase from agromyces sp. and a method of producing a chiral secondary alcohol using same
AU2002211843A1 (en) 2.5-diketo-d-gluconic acid reductases and methods of use
JP2011188771A (ja) リグニンペルオキシダーゼ変異体
SE9904247D0 (sv) Compositions and methods utilizing sequences for controlling nucleic acid expression in yeast
DE602004029690D1 (de) Zusatzmittel zur Herstellung von chromatfreiem Zement
CN104878023A (zh) 一个新型细菌抗逆功能基因及其表达产物与应用
WO2003018824A3 (de) Verfahren zur enzymatischen reduktion von substraten mit molekularem wasserstoff

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties