ATE371041T1 - Kontrolle der immunantworten durch regulierung der aktivität von glykosyltransferasen - Google Patents

Kontrolle der immunantworten durch regulierung der aktivität von glykosyltransferasen

Info

Publication number
ATE371041T1
ATE371041T1 AT98925161T AT98925161T ATE371041T1 AT E371041 T1 ATE371041 T1 AT E371041T1 AT 98925161 T AT98925161 T AT 98925161T AT 98925161 T AT98925161 T AT 98925161T AT E371041 T1 ATE371041 T1 AT E371041T1
Authority
AT
Austria
Prior art keywords
immune responses
activity
regulating
control
glycosyl transferases
Prior art date
Application number
AT98925161T
Other languages
German (de)
English (en)
Inventor
Jamey Marth
James Paulson
Original Assignee
Abaron Biosciences Inc
Univ California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abaron Biosciences Inc, Univ California filed Critical Abaron Biosciences Inc
Application granted granted Critical
Publication of ATE371041T1 publication Critical patent/ATE371041T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C12N15/1137—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against enzymes
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A01K67/027—New or modified breeds of vertebrates
    • A01K67/0271—Chimeric vertebrates, e.g. comprising exogenous cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1048—Glycosyltransferases (2.4)
    • C12N9/1081—Glycosyltransferases (2.4) transferring other glycosyl groups (2.4.99)
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/07—Animals genetically altered by homologous recombination
    • A01K2217/075—Animals genetically altered by homologous recombination inducing loss of function, i.e. knock out

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Environmental Sciences (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Physics & Mathematics (AREA)
  • Virology (AREA)
  • Animal Husbandry (AREA)
  • Cell Biology (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Medicines Containing Plant Substances (AREA)
AT98925161T 1997-05-30 1998-05-29 Kontrolle der immunantworten durch regulierung der aktivität von glykosyltransferasen ATE371041T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US4830397P 1997-05-30 1997-05-30

Publications (1)

Publication Number Publication Date
ATE371041T1 true ATE371041T1 (de) 2007-09-15

Family

ID=21953820

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98925161T ATE371041T1 (de) 1997-05-30 1998-05-29 Kontrolle der immunantworten durch regulierung der aktivität von glykosyltransferasen

Country Status (7)

Country Link
US (2) US6376475B1 (https=)
EP (1) EP1017846B1 (https=)
JP (2) JP4451933B2 (https=)
AT (1) ATE371041T1 (https=)
AU (1) AU7717598A (https=)
DE (1) DE69838298T2 (https=)
WO (1) WO1998054365A1 (https=)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7192914B1 (en) * 1999-09-30 2007-03-20 The Regents Of The University Of California Prevention of atherosclerosis and undesired blood clotting by reducing von Willebrand factor
AU7834800A (en) * 1999-09-30 2001-04-30 Regents Of The University Of California, The Prevention of atherosclerosis and undesired blood clotting by reducing von willebrand factor
DE60140903D1 (de) 2000-10-18 2010-02-04 Brigham & Womens Hospital E-selectin/l-selectin-liganden-polypeptide hämatopoetischer zellen und verfahren zu deren verwendung
US20060210558A1 (en) * 2000-10-18 2006-09-21 Robert Sackstein Hematopoietic cell selectin ligand polypeptides and methods of use thereof
DE60215530T2 (de) * 2001-08-16 2007-05-31 Daiichi Asubio Pharma Co., Ltd. Neues glykolipid, und heilmittel für autoimmunerkrankungen, das dieses als wirkstoff enthält
US20060074047A1 (en) * 2004-10-06 2006-04-06 Cross Alan S Method of treating inflammation with inhibitors of sialyl transferases
JP4359779B2 (ja) * 2006-01-23 2009-11-04 ソニー株式会社 音響再生装置および音響再生方法
GB0614947D0 (en) * 2006-07-27 2006-09-06 Isis Innovation Epitope reduction therapy
US8163551B2 (en) 2008-05-02 2012-04-24 Seattle Genetics, Inc. Methods and compositions for making antibodies and antibody derivatives with reduced core fucosylation
DK2608796T3 (en) * 2010-08-05 2019-03-18 Seattle Genetics Inc Inhibition of protein fucosylation in vivo using fucose analogues
WO2012080975A1 (en) * 2010-12-16 2012-06-21 Basf Se Plants having increased tolerance to herbicides
JP2014159374A (ja) * 2011-05-20 2014-09-04 Nippon Nohyaku Co Ltd 作物の枯凋落葉剤組成物
AR091489A1 (es) * 2012-06-19 2015-02-11 Basf Se Plantas que tienen una mayor tolerancia a herbicidas inhibidores de la protoporfirinogeno oxidasa (ppo)
WO2014031875A1 (en) 2012-08-23 2014-02-27 Seattle Genetics, Inc. Treatment of sickle cell disease and inflammatory conditions
JP2016027002A (ja) * 2012-11-16 2016-02-18 日本農薬株式会社 除草剤組成物
JP6172687B2 (ja) 2013-05-02 2017-08-02 国立研究開発法人産業技術総合研究所 シアリル化糖鎖を認識するモノクローナル抗体
EP3033416A4 (en) * 2013-08-12 2017-02-08 Benaroya Research Institute at Virginia Mason 4-methylumbelliferone treatment for immune modulation

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5352462A (en) * 1982-06-03 1994-10-04 Stolle Research & Development Corporation Anti-inflammatory factor, method of isolation, and use
US5288854A (en) * 1990-11-28 1994-02-22 Center For Blood Research, Inc. Functional derivatives of ICAM-1 which are substantially capable of binding to LFA-1 but are substantially incapable of binding to MAC-1
US5461143A (en) * 1991-03-18 1995-10-24 The Scripps Research Institute Oligosaccharide enzyme substrates and inhibitors: methods and compositions
JPH05247078A (ja) 1992-03-03 1993-09-24 Japan Tobacco Inc 糖化合物、シアル酸含有糖鎖類生合成阻害剤、その製造方法、並びに新規な中間体
US5453272A (en) 1992-10-02 1995-09-26 Alberta Research Council Lectin derived carbohydrate binding-peptide
WO1995034202A1 (en) 1994-06-15 1995-12-21 Alexion Pharmaceuticals, Inc. Methods for reducing hyperacute rejection of xenografts
WO2002028391A1 (en) * 2000-10-06 2002-04-11 The Regents Of The University Of California Blocking inflammation by inhibiting sialylation

Also Published As

Publication number Publication date
EP1017846A4 (en) 2004-08-11
JP2002528037A (ja) 2002-08-27
AU7717598A (en) 1998-12-30
DE69838298D1 (de) 2007-10-04
EP1017846B1 (en) 2007-08-22
US6376475B1 (en) 2002-04-23
US20030013636A1 (en) 2003-01-16
JP4451933B2 (ja) 2010-04-14
EP1017846A1 (en) 2000-07-12
DE69838298T2 (de) 2008-05-15
WO1998054365A1 (en) 1998-12-03
JP2002528036A (ja) 2002-08-27

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