ATE367204T1 - MICROFLUID ANALYZER - Google Patents

MICROFLUID ANALYZER

Info

Publication number
ATE367204T1
ATE367204T1 AT00992452T AT00992452T ATE367204T1 AT E367204 T1 ATE367204 T1 AT E367204T1 AT 00992452 T AT00992452 T AT 00992452T AT 00992452 T AT00992452 T AT 00992452T AT E367204 T1 ATE367204 T1 AT E367204T1
Authority
AT
Austria
Prior art keywords
microfluid
analyzer
shaped
microstructure
base
Prior art date
Application number
AT00992452T
Other languages
German (de)
Inventor
Per Andersson
Arvi Aksberg
Gunnar Ekstrand
Bjoerg Berg
Original Assignee
Gyros Patent Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/EP1999/010347 external-priority patent/WO2000040750A1/en
Application filed by Gyros Patent Ab filed Critical Gyros Patent Ab
Application granted granted Critical
Publication of ATE367204T1 publication Critical patent/ATE367204T1/en

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502761Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip specially adapted for handling suspended solids or molecules independently from the bulk fluid flow, e.g. for trapping or sorting beads, for physically stretching molecules
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502746Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the means for controlling flow resistance, e.g. flow controllers, baffles
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06Fluid handling related problems
    • B01L2200/0605Metering of fluids
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06Fluid handling related problems
    • B01L2200/0647Handling flowable solids, e.g. microscopic beads, cells, particles
    • B01L2200/0668Trapping microscopic beads
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/18Means for temperature control
    • B01L2300/1861Means for temperature control using radiation
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/04Moving fluids with specific forces or mechanical means
    • B01L2400/0403Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0409Moving fluids with specific forces or mechanical means specific forces centrifugal forces
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/06Valves, specific forms thereof
    • B01L2400/0688Valves, specific forms thereof surface tension valves, capillary stop, capillary break

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Hematology (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Fluid Mechanics (AREA)
  • Physics & Mathematics (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Centrifugal Separators (AREA)

Abstract

Microstructure for fluids provided in a rotatable disc (D) having a U-shaped volume-defining structure (7) connected at its base to an inlet arm of a U-shaped chamber (10).
AT00992452T 1999-12-23 2000-12-22 MICROFLUID ANALYZER ATE367204T1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PCT/EP1999/010347 WO2000040750A1 (en) 1998-12-30 1999-12-23 Method for sequencing dna using a microfluidic device
SE0001779A SE0001779D0 (en) 2000-05-12 2000-05-12 Microanalysis device

Publications (1)

Publication Number Publication Date
ATE367204T1 true ATE367204T1 (en) 2007-08-15

Family

ID=20279665

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00992452T ATE367204T1 (en) 1999-12-23 2000-12-22 MICROFLUID ANALYZER

Country Status (7)

Country Link
JP (1) JP4612262B2 (en)
AT (1) ATE367204T1 (en)
AU (1) AU4410501A (en)
CA (1) CA2395159A1 (en)
DE (1) DE60035611T2 (en)
SE (1) SE0001779D0 (en)
WO (1) WO2001046465A2 (en)

Families Citing this family (34)

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Publication number Priority date Publication date Assignee Title
US7026131B2 (en) 2000-11-17 2006-04-11 Nagaoka & Co., Ltd. Methods and apparatus for blood typing with optical bio-discs
US7087203B2 (en) 2000-11-17 2006-08-08 Nagaoka & Co., Ltd. Methods and apparatus for blood typing with optical bio-disc
SE0004297D0 (en) 2000-11-23 2000-11-23 Gyros Ab Device for thermal cycling
SE0004296D0 (en) 2000-11-23 2000-11-23 Gyros Ab Device and method for the controlled heating in micro channel systems
US7054258B2 (en) 2000-12-08 2006-05-30 Nagaoka & Co., Ltd. Optical disc assemblies for performing assays
WO2002046721A2 (en) 2000-12-08 2002-06-13 Burstein Technologies, Inc. Optical discs for measuring analytes
US7091034B2 (en) 2000-12-15 2006-08-15 Burstein Technologies, Inc. Detection system for disk-based laboratory and improved optical bio-disc including same
US7429354B2 (en) 2001-03-19 2008-09-30 Gyros Patent Ab Structural units that define fluidic functions
US7759067B2 (en) 2001-03-19 2010-07-20 Gyros Patent Ab Method for determining the amount of an analyte with a disc-shaped microfluidic device
US6919058B2 (en) 2001-08-28 2005-07-19 Gyros Ab Retaining microfluidic microcavity and other microfluidic structures
EP2281633A1 (en) 2001-08-28 2011-02-09 Gyros Patent Ab Retaining microfluidic microcavity and other microfluidic structures
WO2003024598A1 (en) * 2001-09-17 2003-03-27 Gyros Ab Functional unit enabling controlled flow in a microfluidic device
DE60237289D1 (en) 2001-09-17 2010-09-23 Gyros Patent Ab A CONTROLLED POWER IN A MICROFLUID DEVICE ENABLING FUNCTION UNIT
CN100382870C (en) * 2001-12-28 2008-04-23 株式会社日立高新技术 Extractor, chemical analyzer and chemical analyzing method
JP4338529B2 (en) 2002-04-08 2009-10-07 ユロス・パテント・アクチボラゲット Homing process
AU2003224586A1 (en) * 2002-04-30 2003-11-17 Gyros Ab Integrated microfluidic device (ea)
CN1650173B (en) * 2002-04-30 2012-06-06 爱科来株式会社 Analysis instrument, sample analysis method and analysis device using the instrument, and method of forming opening in the instrument
US7005265B1 (en) 2002-06-20 2006-02-28 Wenhong Fan Nonenzymatic catalytic signal amplification for nucleic acid hybridization assays
EP1552285B1 (en) 2002-10-13 2010-04-14 Picosep A/S A two-dimensional microfluid biomolecule separation system
SE0301945D0 (en) 2003-06-30 2003-06-30 Gyros Ab Confidence determination
US20060210426A1 (en) * 2003-08-05 2006-09-21 Taiyo Yuden Co., Ltd. Sample analyzer and disk-like sample analyzing medium
JP2007524849A (en) * 2004-01-06 2007-08-30 ユィロス・パテント・アクチボラグ Contact heating arrangement
WO2006110095A1 (en) 2005-04-14 2006-10-19 Gyros Patent Ab A microfluidic device with finger valves
GB2464721C (en) 2008-10-23 2013-08-14 Biosurfit Sa Jet deflection device
GB2466644B (en) * 2008-12-30 2011-05-11 Biosurfit Sa Liquid handling
JP5521454B2 (en) * 2009-09-15 2014-06-11 凸版印刷株式会社 Sample analysis chip, sample analysis apparatus and sample analysis method using the same
GB2476474B (en) 2009-12-22 2012-03-28 Biosurfit Sa Surface plasmon resonance detection system
GB2479139A (en) 2010-03-29 2011-10-05 Biosurfit Sa A liquid distribution and metering device
EP2486978A1 (en) 2010-10-28 2012-08-15 Roche Diagnostics GmbH Microfluid test carrier for separating a fluid volume in partial volumes
EP2455162A1 (en) 2010-10-29 2012-05-23 Roche Diagnostics GmbH Microfluidic element for analysing a fluid sample
US9933348B2 (en) 2011-12-08 2018-04-03 Biosurfit, S.A. Sequential aliqoting and determination of an indicator of sedimentation rate
JP5549719B2 (en) * 2012-09-20 2014-07-16 ブラザー工業株式会社 Inspection target
US9993819B2 (en) 2014-12-30 2018-06-12 Stmicroelectronics S.R.L. Apparatus for actuating and reading a centrifugal microfluidic disk for biological and biochemical analyses, and use of the apparatus
WO2017154750A1 (en) * 2016-03-11 2017-09-14 パナソニック株式会社 Disk for liquid sample inspection and filter cartridge used in same, disk body, measurement plate, sample detection plate, fluorescence detection system, and fluorescence detection method

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3547547A (en) * 1969-03-13 1970-12-15 Atomic Energy Commission Analytical photometer with means for measuring,holding and transferring discrete liquid volumes and method of use thereof
US4284602A (en) * 1979-12-10 1981-08-18 Immutron, Inc. Integrated fluid manipulator
US4632908A (en) * 1984-05-03 1986-12-30 Abbott Laboratories Heating system for rotating members
US5160702A (en) * 1989-01-17 1992-11-03 Molecular Devices Corporation Analyzer with improved rotor structure
US5230866A (en) * 1991-03-01 1993-07-27 Biotrack, Inc. Capillary stop-flow junction having improved stability against accidental fluid flow
WO1993019827A1 (en) * 1992-04-02 1993-10-14 Abaxis, Inc. Analytical rotor with dye mixing chamber
US5591643A (en) * 1993-09-01 1997-01-07 Abaxis, Inc. Simplified inlet channels
US6299839B1 (en) * 1995-08-31 2001-10-09 First Medical, Inc. System and methods for performing rotor assays
JP2002503336A (en) * 1997-05-16 2002-01-29 アルバータ リサーチ カウンシル Micro-distribution system and method of using the same
US6063589A (en) * 1997-05-23 2000-05-16 Gamera Bioscience Corporation Devices and methods for using centripetal acceleration to drive fluid movement on a microfluidics system
US5919711A (en) * 1997-08-07 1999-07-06 Careside, Inc. Analytical cartridge
US5916522A (en) * 1997-08-07 1999-06-29 Careside, Inc. Electrochemical analytical cartridge
GB9828785D0 (en) * 1998-12-30 1999-02-17 Amersham Pharm Biotech Ab Sequencing systems

Also Published As

Publication number Publication date
WO2001046465A2 (en) 2001-06-28
WO2001046465A3 (en) 2001-12-27
JP2003518250A (en) 2003-06-03
DE60035611D1 (en) 2007-08-30
DE60035611T2 (en) 2008-05-21
AU4410501A (en) 2001-07-03
SE0001779D0 (en) 2000-05-12
CA2395159A1 (en) 2001-06-28
JP4612262B2 (en) 2011-01-12

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Legal Events

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RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties