ATE367151T1 - Kernformulierung - Google Patents
KernformulierungInfo
- Publication number
- ATE367151T1 ATE367151T1 AT01930970T AT01930970T ATE367151T1 AT E367151 T1 ATE367151 T1 AT E367151T1 AT 01930970 T AT01930970 T AT 01930970T AT 01930970 T AT01930970 T AT 01930970T AT E367151 T1 ATE367151 T1 AT E367151T1
- Authority
- AT
- Austria
- Prior art keywords
- core formulation
- rosiglitazone
- core
- formulation
- biguanide
- Prior art date
Links
- 238000009472 formulation Methods 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- YASAKCUCGLMORW-UHFFFAOYSA-N Rosiglitazone Chemical compound C=1C=CC=NC=1N(C)CCOC(C=C1)=CC=C1CC1SC(=O)NC1=O YASAKCUCGLMORW-UHFFFAOYSA-N 0.000 abstract 4
- 229960004586 rosiglitazone Drugs 0.000 abstract 2
- 229940123208 Biguanide Drugs 0.000 abstract 1
- XNCOSPRUTUOJCJ-UHFFFAOYSA-N Biguanide Chemical compound NC(N)=NC(N)=N XNCOSPRUTUOJCJ-UHFFFAOYSA-N 0.000 abstract 1
- 229940000425 combination drug Drugs 0.000 abstract 1
- 229960003105 metformin Drugs 0.000 abstract 1
- XZWYZXLIPXDOLR-UHFFFAOYSA-N metformin Chemical compound CN(C)C(=N)NC(N)=N XZWYZXLIPXDOLR-UHFFFAOYSA-N 0.000 abstract 1
- 239000000825 pharmaceutical preparation Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
- A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Hematology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Obesity (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Molds, Cores, And Manufacturing Methods Thereof (AREA)
- Non-Silver Salt Photosensitive Materials And Non-Silver Salt Photography (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US20156700P | 2000-05-01 | 2000-05-01 | |
| US70233200A | 2000-10-31 | 2000-10-31 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE367151T1 true ATE367151T1 (de) | 2007-08-15 |
Family
ID=26896877
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT01930970T ATE367151T1 (de) | 2000-05-01 | 2001-05-01 | Kernformulierung |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP1278513B1 (enExample) |
| JP (1) | JP2004516234A (enExample) |
| AT (1) | ATE367151T1 (enExample) |
| AU (2) | AU2001257456B2 (enExample) |
| CA (1) | CA2407713A1 (enExample) |
| DE (1) | DE60129425T2 (enExample) |
| ES (1) | ES2290130T3 (enExample) |
| WO (1) | WO2001082867A2 (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IN192749B (enExample) * | 2002-11-15 | 2004-05-15 | Ranbaxy Lab Ltd | |
| PE20050335A1 (es) * | 2003-08-07 | 2005-06-01 | Sb Pharmco Inc | Forma de dosificacion oral que comprende 5-[4-[2-(n-metil-n-(2-piridil)amino)etoxi]bencil]tiazolidin-2,4-diona y procedimiento para la preparacion |
| GB0318824D0 (en) * | 2003-08-11 | 2003-09-10 | Glaxo Group Ltd | Novel composition |
| WO2005065663A1 (en) * | 2003-12-31 | 2005-07-21 | Alpharma, Inc. | Rosiglitazone and metformin formulations |
| EP1732513A2 (en) * | 2003-12-31 | 2006-12-20 | Alpharma, Inc. | Rosiglitazone formulations |
| FR2896159B1 (fr) * | 2006-01-13 | 2008-09-12 | Merck Sante Soc Par Actions Si | Combinaison de derives de triazine et d'agents sensibilisateurs a l'insuline. |
| RU2554740C2 (ru) * | 2009-05-01 | 2015-06-27 | Апталис Фарматек, Инк. | Композиции перорально распадающихся таблеток, содержащие комбинации высоко- и низкодозовых лекарственных средств |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4166800A (en) * | 1977-08-25 | 1979-09-04 | Sandoz, Inc. | Processes for preparation of microspheres |
| JPH05503934A (ja) * | 1990-01-30 | 1993-06-24 | アクゾ・エヌ・ヴエー | 壁により完全に包囲され、１種以上の活性物質で全部又は一部を充填した中空空間から成る、活性物質の調節送達のための物品 |
| AUPM897594A0 (en) * | 1994-10-25 | 1994-11-17 | Daratech Pty Ltd | Controlled release container |
| US6011049A (en) * | 1997-02-19 | 2000-01-04 | Warner-Lambert Company | Combinations for diabetes |
| KR20060105005A (ko) * | 1997-06-18 | 2006-10-09 | 스미스클라인비이참피이엘시이 | 티아졸리딘디온 및 메트포르민을 사용한 당뇨병의 치료 |
| US6099862A (en) * | 1998-08-31 | 2000-08-08 | Andrx Corporation | Oral dosage form for the controlled release of a biguanide and sulfonylurea |
| WO2001035940A2 (en) * | 1999-11-16 | 2001-05-25 | Smithkline Beecham P.L.C. | Pharmaceutical composition comprising a thiazolidinedione-metformin hydrochloride |
| MY125516A (en) * | 1999-11-16 | 2006-08-30 | Smithkline Beecham Plc | Novel composition based on thiazolidinedione and metformin and use |
-
2001
- 2001-05-01 WO PCT/US2001/013988 patent/WO2001082867A2/en not_active Ceased
- 2001-05-01 AT AT01930970T patent/ATE367151T1/de not_active IP Right Cessation
- 2001-05-01 DE DE60129425T patent/DE60129425T2/de not_active Expired - Fee Related
- 2001-05-01 AU AU2001257456A patent/AU2001257456B2/en not_active Ceased
- 2001-05-01 EP EP01930970A patent/EP1278513B1/en not_active Expired - Lifetime
- 2001-05-01 AU AU5745601A patent/AU5745601A/xx active Pending
- 2001-05-01 JP JP2001579743A patent/JP2004516234A/ja active Pending
- 2001-05-01 ES ES01930970T patent/ES2290130T3/es not_active Expired - Lifetime
- 2001-05-01 CA CA002407713A patent/CA2407713A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| ES2290130T3 (es) | 2008-02-16 |
| CA2407713A1 (en) | 2001-11-08 |
| JP2004516234A (ja) | 2004-06-03 |
| AU5745601A (en) | 2001-11-12 |
| WO2001082867A3 (en) | 2002-03-07 |
| DE60129425T2 (de) | 2008-04-17 |
| EP1278513A4 (en) | 2005-01-26 |
| EP1278513B1 (en) | 2007-07-18 |
| EP1278513A2 (en) | 2003-01-29 |
| WO2001082867A2 (en) | 2001-11-08 |
| DE60129425D1 (de) | 2007-08-30 |
| AU2001257456B2 (en) | 2006-02-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 1278513 Country of ref document: EP |
|
| REN | Ceased due to non-payment of the annual fee |