ATE357226T1 - (d)-methadon, ein nicht-opioides schmerzmittel - Google Patents

(d)-methadon, ein nicht-opioides schmerzmittel

Info

Publication number
ATE357226T1
ATE357226T1 AT98904609T AT98904609T ATE357226T1 AT E357226 T1 ATE357226 T1 AT E357226T1 AT 98904609 T AT98904609 T AT 98904609T AT 98904609 T AT98904609 T AT 98904609T AT E357226 T1 ATE357226 T1 AT E357226T1
Authority
AT
Austria
Prior art keywords
alpha
subject
methadone
pain relief
normethadol
Prior art date
Application number
AT98904609T
Other languages
English (en)
Inventor
Charles E Inturrisi
Original Assignee
Cornell Res Foundation Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cornell Res Foundation Inc filed Critical Cornell Res Foundation Inc
Application granted granted Critical
Publication of ATE357226T1 publication Critical patent/ATE357226T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/36—Opioid-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
AT98904609T 1997-01-22 1998-01-21 (d)-methadon, ein nicht-opioides schmerzmittel ATE357226T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US3530897P 1997-01-22 1997-01-22

Publications (1)

Publication Number Publication Date
ATE357226T1 true ATE357226T1 (de) 2007-04-15

Family

ID=21881853

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98904609T ATE357226T1 (de) 1997-01-22 1998-01-21 (d)-methadon, ein nicht-opioides schmerzmittel

Country Status (12)

Country Link
US (1) US6008258A (de)
EP (1) EP1003494B1 (de)
JP (2) JP4514241B2 (de)
AT (1) ATE357226T1 (de)
AU (1) AU6244898A (de)
CA (1) CA2278422C (de)
DE (1) DE69837387T2 (de)
DK (1) DK1003494T3 (de)
ES (1) ES2283049T3 (de)
MA (1) MA24794A1 (de)
PT (1) PT1003494E (de)
WO (1) WO1998031358A1 (de)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6242456B1 (en) * 1998-03-09 2001-06-05 Trustees Of Tufts College Treatment of stereotypic, self-injurious and compulsive behaviors in man and animals using antagonists of NMDA receptors
US20070197651A1 (en) * 1998-03-09 2007-08-23 Tufts University Treatment of stereotypic, self-injurious and compulsive behaviors in man and animals using antagonists of NMDA receptors
US20060167114A1 (en) * 1998-03-09 2006-07-27 Louis Shuster Treatment of stereotypic, self-injurious and compulsive behaviors in man and animals using antagonists of NMDA receptors
WO2000003716A1 (en) * 1998-07-16 2000-01-27 Memorial Sloan-Kettering Cancer Center Topical compositions comprising an opioid analgesic and an nmda antagonist
US6897242B1 (en) * 1999-02-24 2005-05-24 Judson J. Somerville Non-racemic mixtures of d- and l- methadone and method of treating pain
AU2001251374A1 (en) * 2000-04-07 2001-10-23 Ultramed International, Inc. Maintaining abstinence after detoxification from opiate addiction
AU2001257326A1 (en) 2000-04-28 2001-11-12 Memorial Sloan-Kettering Cancer Center Topical anesthetic/opioid formulations and uses thereof
US7820688B2 (en) 2001-04-27 2010-10-26 Memorial Sloan-Kettering Cancer Center Topical anesthetic/opioid formulations and uses thereof
AU2003210486B2 (en) * 2002-01-16 2007-06-28 Endo Pharmaceuticals Inc. Pharmaceutical composition and method for treating disorders of the central nervous system
WO2003061594A2 (en) * 2002-01-23 2003-07-31 The Regents Of The University Of California Methods and compositions for reducing the development of drug tolerance and/or physical dependence
AU2003220601A1 (en) * 2002-03-27 2003-10-13 Memorial Sloan-Kettering Cancer Center Synergistic l-methadone compositions and methods of use thereof
AU2003301808A1 (en) * 2002-05-13 2004-06-07 Endo Pharmaceuticals Inc. Abuse-resistant opioid dosage form
WO2004022002A2 (en) * 2002-09-09 2004-03-18 Endo Pharmaceuticals Inc. Combined immediate release and extended release analgesic composition
US20040180915A1 (en) * 2003-03-14 2004-09-16 Xanodyne Pharmacal, Inc. Methadone-containing compositions for parenteral administration and method of use thereof
US20040202717A1 (en) 2003-04-08 2004-10-14 Mehta Atul M. Abuse-resistant oral dosage forms and method of use thereof
US20100010096A1 (en) * 2006-10-27 2010-01-14 John Charin Somberg Methadone chiral isolate as an improved pharmaceutical
US20100048605A1 (en) * 2006-12-11 2010-02-25 University Of Kentucky Research Foundation Synergistic effects of combinations of nornicotine and opioids for the treatment of pain
US9468611B2 (en) * 2012-09-27 2016-10-18 Relmada Therapeutics, Inc. d-Methadone for the treatment of psychiatric symptoms
EP3576739A2 (de) 2017-01-31 2019-12-11 Paolo L. Manfredi Verbindungen zur behandlung oder prävention von erkrankungen des nervensystems sowie symptomen und manifestationen davon und zum zytoschutz gegen krankheiten und alterung von zellen sowie symptomen und manifestationen davon
WO2018183320A1 (en) * 2017-03-31 2018-10-04 Depco, Inc. Therapeutic putty having analgesics and/or counterirritants

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3895056A (en) * 1972-12-26 1975-07-15 Lilly Co Eli Alpha-d1-4-acetoxy-1-methyl-3,3-diphenylhexylamine and salts
US5321012A (en) * 1993-01-28 1994-06-14 Virginia Commonwealth University Medical College Inhibiting the development of tolerance to and/or dependence on a narcotic addictive substance
CA2115792C (en) * 1993-03-05 2005-11-01 David J. Mayer Method for the treatment of pain
US5352683A (en) * 1993-03-05 1994-10-04 Virginia Commonwealth University Medical College Of Virginia Method for the treatment of chronic pain

Also Published As

Publication number Publication date
EP1003494A4 (de) 2002-10-16
AU6244898A (en) 1998-08-07
WO1998031358A1 (en) 1998-07-23
EP1003494A1 (de) 2000-05-31
CA2278422C (en) 2007-11-13
CA2278422A1 (en) 1998-07-23
JP2001508797A (ja) 2001-07-03
US6008258A (en) 1999-12-28
JP2010013477A (ja) 2010-01-21
DE69837387T2 (de) 2007-12-13
JP4514241B2 (ja) 2010-07-28
ES2283049T3 (es) 2007-10-16
EP1003494B1 (de) 2007-03-21
DK1003494T3 (da) 2007-07-16
MA24794A1 (fr) 1999-12-31
DE69837387D1 (de) 2007-05-03
PT1003494E (pt) 2007-06-06

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Legal Events

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RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties