ATE353369T1 - Polypeptide der menschlichen hyaluronan-synthase und dafür kodierende dns - Google Patents
Polypeptide der menschlichen hyaluronan-synthase und dafür kodierende dnsInfo
- Publication number
- ATE353369T1 ATE353369T1 AT97908558T AT97908558T ATE353369T1 AT E353369 T1 ATE353369 T1 AT E353369T1 AT 97908558 T AT97908558 T AT 97908558T AT 97908558 T AT97908558 T AT 97908558T AT E353369 T1 ATE353369 T1 AT E353369T1
- Authority
- AT
- Austria
- Prior art keywords
- hyaluronan synthase
- polypeptides
- dna coding
- coding therefor
- dna
- Prior art date
Links
- 102000003918 Hyaluronan Synthases Human genes 0.000 title abstract 4
- 108090000320 Hyaluronan Synthases Proteins 0.000 title abstract 4
- 229920001184 polypeptide Polymers 0.000 title abstract 3
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 3
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 3
- 125000003275 alpha amino acid group Chemical group 0.000 abstract 1
- 125000000539 amino acid group Chemical group 0.000 abstract 1
- 230000037430 deletion Effects 0.000 abstract 1
- 238000012217 deletion Methods 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- KIUKXJAPPMFGSW-MNSSHETKSA-N hyaluronan Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)C1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H](C(O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-MNSSHETKSA-N 0.000 abstract 1
- 229940099552 hyaluronan Drugs 0.000 abstract 1
- 229920002674 hyaluronan Polymers 0.000 abstract 1
- 230000037431 insertion Effects 0.000 abstract 1
- 238000003780 insertion Methods 0.000 abstract 1
- 238000006467 substitution reaction Methods 0.000 abstract 1
- 230000002194 synthesizing effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1048—Glycosyltransferases (2.4)
- C12N9/1051—Hexosyltransferases (2.4.1)
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Enzymes And Modification Thereof (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP8432696 | 1996-04-05 | ||
| JP10966396 | 1996-04-30 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE353369T1 true ATE353369T1 (de) | 2007-02-15 |
Family
ID=26425378
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT97908558T ATE353369T1 (de) | 1996-04-05 | 1997-03-31 | Polypeptide der menschlichen hyaluronan-synthase und dafür kodierende dns |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US6162908A (de) |
| EP (1) | EP0893506B1 (de) |
| JP (1) | JP3795925B2 (de) |
| AT (1) | ATE353369T1 (de) |
| DE (1) | DE69737321T2 (de) |
| WO (1) | WO1997038113A1 (de) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6423514B1 (en) | 1996-04-22 | 2002-07-23 | Millennium Pharmaceuticals, Inc. | Mammalian hyaluronan synthases, nucleic acids and uses thereof |
| US5994100A (en) * | 1997-05-29 | 1999-11-30 | Smithkline Beecham Corporation | HAS2 splicing variant HOEFC11: a target in chronic renal failure, inflammatory diseases and myocardial ischemia |
| CA2369342A1 (en) * | 1999-04-21 | 2000-10-26 | Incyte Genomics, Inc. | Carbohydrate-modifying enzymes |
| WO2007091644A1 (ja) * | 2006-02-10 | 2007-08-16 | Seikagaku Corporation | 真菌増殖抑制剤 |
| US9511119B2 (en) * | 2013-03-15 | 2016-12-06 | NuTech Spine, Inc. | Preparations containing hepatocyte growth factor and hyaluronic acid and methods of making and using same |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2942813B2 (ja) * | 1996-02-26 | 1999-08-30 | 科学技術庁長官官房会計課長 | 新規なヒアルロン酸合成酵素のポリペプチド及びそれをコードするｄｎａ |
| US6423514B1 (en) * | 1996-04-22 | 2002-07-23 | Millennium Pharmaceuticals, Inc. | Mammalian hyaluronan synthases, nucleic acids and uses thereof |
| US6602693B1 (en) * | 1996-07-03 | 2003-08-05 | Clear Solutions Biotech, Inc. | Gene encoding hyaluronan synthase |
-
1997
- 1997-03-31 EP EP97908558A patent/EP0893506B1/de not_active Expired - Lifetime
- 1997-03-31 AT AT97908558T patent/ATE353369T1/de not_active IP Right Cessation
- 1997-03-31 US US09/155,768 patent/US6162908A/en not_active Expired - Lifetime
- 1997-03-31 DE DE69737321T patent/DE69737321T2/de not_active Expired - Lifetime
- 1997-03-31 JP JP53604097A patent/JP3795925B2/ja not_active Expired - Fee Related
- 1997-03-31 WO PCT/JP1997/001111 patent/WO1997038113A1/ja not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| EP0893506B1 (de) | 2007-02-07 |
| WO1997038113A1 (fr) | 1997-10-16 |
| JP3795925B2 (ja) | 2006-07-12 |
| EP0893506A1 (de) | 1999-01-27 |
| US6162908A (en) | 2000-12-19 |
| EP0893506A4 (de) | 2004-04-28 |
| DE69737321T2 (de) | 2007-12-20 |
| DE69737321D1 (de) | 2007-03-22 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |