ATE347697T1 - Methode zur bestimmung von proteinfragmenten in körperflüssigkeiten - Google Patents

Methode zur bestimmung von proteinfragmenten in körperflüssigkeiten

Info

Publication number
ATE347697T1
ATE347697T1 AT96908100T AT96908100T ATE347697T1 AT E347697 T1 ATE347697 T1 AT E347697T1 AT 96908100 T AT96908100 T AT 96908100T AT 96908100 T AT96908100 T AT 96908100T AT E347697 T1 ATE347697 T1 AT E347697T1
Authority
AT
Austria
Prior art keywords
body fluid
protein fragments
determining protein
collagen
breakdown products
Prior art date
Application number
AT96908100T
Other languages
English (en)
Inventor
Christian Fledelius
Martin Bonde
Per Qvist
Original Assignee
Osteometer Biotech As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Osteometer Biotech As filed Critical Osteometer Biotech As
Application granted granted Critical
Publication of ATE347697T1 publication Critical patent/ATE347697T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/78—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin or cold insoluble globulin [CIG]
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6887—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids from muscle, cartilage or connective tissue

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Zoology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT96908100T 1995-03-24 1996-03-21 Methode zur bestimmung von proteinfragmenten in körperflüssigkeiten ATE347697T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9506050.5A GB9506050D0 (en) 1995-03-24 1995-03-24 Assaying collagen fragments in body fluids

Publications (1)

Publication Number Publication Date
ATE347697T1 true ATE347697T1 (de) 2006-12-15

Family

ID=10771833

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96908100T ATE347697T1 (de) 1995-03-24 1996-03-21 Methode zur bestimmung von proteinfragmenten in körperflüssigkeiten

Country Status (11)

Country Link
US (1) US6210902B1 (de)
EP (1) EP0820598B1 (de)
JP (1) JPH11502622A (de)
CN (1) CN100430727C (de)
AT (1) ATE347697T1 (de)
AU (1) AU712375B2 (de)
BR (1) BR9607854A (de)
DE (1) DE69636749T2 (de)
ES (1) ES2278383T3 (de)
GB (1) GB9506050D0 (de)
WO (1) WO1996030765A1 (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9506050D0 (en) 1995-03-24 1995-05-10 Osteometer A S Assaying collagen fragments in body fluids
EP0787301B1 (de) 1994-10-17 2001-02-14 Osteometer Biotech AS Einschätzung der fragmentierungsmuster von kollagen in körperflüssigkeiten und diagnose von mit dem kollagenmetabolismus zusammenhängenden störungen
US6107047A (en) * 1996-03-21 2000-08-22 Osteometer Biotech A/S Assaying protein fragments in body fluids
GB9617616D0 (en) 1996-08-22 1996-10-02 Osteometer Biotech As Assaying protein fragments in body fluids
EP0944833B1 (de) * 1996-12-09 2001-06-27 Osteometer Biotech AS Sandwichtest zum nachweis von kollagenfragmenten
AU752227B2 (en) * 1997-07-31 2002-09-12 General Hospital Corporation, The Collagen-peptide assay method
US6117646A (en) * 1997-09-22 2000-09-12 Osteometer Biotech A/S Assaying protein fragments in body fluids
GB9928052D0 (en) * 1999-11-26 2000-01-26 Osteometer Biotech As Assay of isomerised and/or optically inverted proteins and protein fragments
US7354723B2 (en) 1999-11-26 2008-04-08 Nordic Bioscience Dagnostics A/S Assay of isomerised and/or optically inverted proteins and protein fragments
US8639009B2 (en) 2000-10-11 2014-01-28 Imatx, Inc. Methods and devices for evaluating and treating a bone condition based on x-ray image analysis
US7660453B2 (en) 2000-10-11 2010-02-09 Imaging Therapeutics, Inc. Methods and devices for analysis of x-ray images
GB0112626D0 (en) 2001-05-23 2001-07-18 Osteometer Biotech As Assay of isomerised and/or optically inverted proteins and protein fragments
ATE440536T1 (de) * 2001-05-25 2009-09-15 Imaging Therapeutics Inc Verfahren zur diagnose, behandlung und prävention von knochenverlust
US8965075B2 (en) 2002-09-16 2015-02-24 Imatx, Inc. System and method for predicting future fractures
EP1605824A2 (de) 2003-03-25 2005-12-21 Imaging Therapeutics, Inc. Verfahren zur kompensation der bildgebenden technik bei der bearbeitung von röntgenaufnahmen
US20050124071A1 (en) * 2003-09-30 2005-06-09 Kraus Virginia B. Methods and compositions for diagnosing musculoskeletal, arthritic and joint disorders by biomarker dating
WO2009091581A2 (en) * 2008-01-18 2009-07-23 Vatrix Medical, Inc. Diagnostic biomarkers for vascular aneurysm
CN109813911A (zh) * 2017-11-22 2019-05-28 江阴贝瑞森生化技术有限公司 一种可定量可追踪的测定贻贝粘蛋白降解的方法

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL6716836A (de) 1967-12-11 1969-06-13
DE2816841A1 (de) 1978-04-18 1979-10-31 Max Planck Gesellschaft Radioimmunologische bestimmung von prokollagen (typ iii) und prokollagen- peptid (typ iii)
DE3209149A1 (de) 1982-03-13 1983-10-06 Hoechst Ag Verfahren zur gemeinsamen immunologischen bestimmung von prokollagen-peptid (typ iii) und prokollagen-peptid col 1 (typ iii) und verfahren zur herstellung von anti-prokollagen-peptid col 1 (typ iii)-serum
US4628027A (en) 1982-05-19 1986-12-09 Molecular Engineering Associates, Ltd. Vitro diagnostic methods using monoclonal antibodies against connective tissue proteins
CA1251729A (en) 1982-05-19 1989-03-28 Steffen Gay In vitro diagnostic methods using monoclonal antibodies against connective tissue proteins
SE8304836D0 (sv) 1983-09-09 1983-09-09 Pharmacia Ab Sett att bestemma forendringar i ledbrosk
US5001225A (en) 1986-12-08 1991-03-19 Georgetown University Monoclonal antibodies to a pan-malarial antigen
US5679583A (en) 1987-05-02 1997-10-21 Hoechst Aktiengesellschaft Monoclonal antibodies for the selective immunological determination of intact procollagen peptide (type III) and procollagen (type III) in body fluids
DE3714634A1 (de) 1987-05-02 1988-11-17 Hoechst Ag Verfahren zur selektiven immunologischen bestimmung von intaktem prokollagen peptid (typ iii) und prokollagen (typ iii) in koerperfluessigkeiten und mittel zu dessen durchfuehrung
GB2205643B (en) 1987-05-08 1991-03-13 Farmos Group Limited Type iii collagen degradation assay
US5962639A (en) 1987-11-06 1999-10-05 Washington Research Foundation Synthetic peptides corresponding to telopeptide sequences of cross-linked type I collagen metabolites
US5300434A (en) 1987-11-06 1994-04-05 Washington Research Foundation Hybridoma cell line producing an antibody to type-I collagen amino-terminal telopeptide
US5320970A (en) 1987-11-06 1994-06-14 Washington Research Foundation Detection of collagen degradation in vivo
US4973666A (en) 1987-11-06 1990-11-27 Washington Research Foundation Peptide fragments containing HP and LP cross-links
ES2065350T3 (es) 1988-04-27 1995-02-16 Hoechst Ag Anticuerpo monoclonal para la determinacion immunologica selectiva de peptido (tipo iii) intacto y procolageno (tipo iii) en liquidos corporales.
GB8815174D0 (en) 1988-06-25 1988-08-03 Rowett Research Inst Method of monitoring collagen degradation
CA2001373A1 (en) 1988-10-24 1990-04-24 Bruce Caterson Methods and compositions for diagnosing, monitoring and treating the early stage of osteoarthritis
WO1990008195A1 (en) 1989-01-13 1990-07-26 President And Fellows Of Harvard College Monoclonal antibody to human type ix collagen
ZA909755B (en) 1989-12-07 1991-09-25 Res Dev Foundation Cell cycle-dependent regulation of phosphorylation of the human retinoblastoma gene product
GB9014220D0 (en) 1990-06-26 1990-08-15 Farmos Yhtymy Oy Method for the immunlolgical determinition of the carboxyterminal propeptide of type i procollagen
GB9105893D0 (en) 1991-03-20 1991-05-08 Orion Yhtymae Oy Bone resorption assay based on a peptide liberated during collagen degradation
DE4225038C2 (de) 1992-07-29 1995-11-30 Boehringer Mannheim Gmbh Herstellung und Verwendung von Antikörpern gegen Kollagen
JPH08505149A (ja) 1992-12-28 1996-06-04 ジェイ． ベイリンク，デビッド 骨再吸収検定法
JP2703116B2 (ja) 1993-07-28 1998-01-26 ベーリンガー マンハイム ゲーエムベーハー コラーゲンまたはコラーゲン断片を検出するためのイムノアッセイ
DK104093D0 (da) 1993-09-17 1993-09-17 Osteometer A S Fremgangsmaade til bestemmelse af collagen-fragmenter i legemsvaesker, test-kit og midler til udoevelse af fremgangsmaaden og anvendelse af fremgangsmaaden til diagnosticering af lidelser associeret til collagen-metabolismen
GB9506050D0 (en) 1995-03-24 1995-05-10 Osteometer A S Assaying collagen fragments in body fluids
US5763272A (en) 1994-12-23 1998-06-09 Boehringer Mannheim Gmbh Hybridoma for producing antibody for collagen I
EP0718309B1 (de) 1994-12-23 1999-04-07 Roche Diagnostics GmbH Antigene und Antikörper zum Nachweis von Kollagen I

Also Published As

Publication number Publication date
JPH11502622A (ja) 1999-03-02
AU5146896A (en) 1996-10-16
CN1185209A (zh) 1998-06-17
ES2278383T3 (es) 2007-08-01
CN100430727C (zh) 2008-11-05
US6210902B1 (en) 2001-04-03
EP0820598A1 (de) 1998-01-28
WO1996030765A1 (en) 1996-10-03
EP0820598B1 (de) 2006-12-06
AU712375B2 (en) 1999-11-04
DE69636749T2 (de) 2007-04-05
GB9506050D0 (en) 1995-05-10
DE69636749D1 (de) 2007-01-18
BR9607854A (pt) 1998-06-30

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