ATE346089T1 - Kristallstruktur (3 â auflösung) des ribosoms 30s und ihre verwendung - Google Patents

Kristallstruktur (3 â auflösung) des ribosoms 30s und ihre verwendung

Info

Publication number
ATE346089T1
ATE346089T1 AT01306060T AT01306060T ATE346089T1 AT E346089 T1 ATE346089 T1 AT E346089T1 AT 01306060 T AT01306060 T AT 01306060T AT 01306060 T AT01306060 T AT 01306060T AT E346089 T1 ATE346089 T1 AT E346089T1
Authority
AT
Austria
Prior art keywords
ribosome
angstrom
resolution
crystal structure
provides
Prior art date
Application number
AT01306060T
Other languages
English (en)
Inventor
Venkatraman Ramakrishnan
Ditlev Egeskov Brodersen
Andrew Philip Carter
Brian Thomas Wimberly
Jr William Melvon Clemons
Original Assignee
Medical Res Council
Univ Utah Res Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0017376A external-priority patent/GB0017376D0/en
Application filed by Medical Res Council, Univ Utah Res Found filed Critical Medical Res Council
Application granted granted Critical
Publication of ATE346089T1 publication Critical patent/ATE346089T1/de

Links

Classifications

    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B15/00—ICT specially adapted for analysing two-dimensional [2D] or three-dimensional [3D] molecular structures, e.g. structural or functional relations or structure alignment
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/18—Testing for antimicrobial activity of a material
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2299/00—Coordinates from 3D structures of peptides, e.g. proteins or enzymes

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Biomedical Technology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Hematology (AREA)
  • General Engineering & Computer Science (AREA)
  • Evolutionary Biology (AREA)
  • Medical Informatics (AREA)
  • Food Science & Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Toxicology (AREA)
  • Theoretical Computer Science (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Cell Biology (AREA)
  • Peptides Or Proteins (AREA)
  • Analysing Materials By The Use Of Radiation (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
AT01306060T 2000-07-14 2001-07-13 Kristallstruktur (3 â auflösung) des ribosoms 30s und ihre verwendung ATE346089T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0017376A GB0017376D0 (en) 2000-07-14 2000-07-14 Crystal structure
GB0022943A GB0022943D0 (en) 2000-07-14 2000-09-19 Crystal structure (II)

Publications (1)

Publication Number Publication Date
ATE346089T1 true ATE346089T1 (de) 2006-12-15

Family

ID=26244665

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01306060T ATE346089T1 (de) 2000-07-14 2001-07-13 Kristallstruktur (3 â auflösung) des ribosoms 30s und ihre verwendung

Country Status (9)

Country Link
US (1) US6925394B2 (de)
EP (1) EP1172374B1 (de)
JP (1) JP2005194188A (de)
AT (1) ATE346089T1 (de)
AU (1) AU783778B2 (de)
CA (1) CA2352399A1 (de)
DE (1) DE60124628T2 (de)
GB (3) GB0029870D0 (de)
IL (1) IL144083A0 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6947844B2 (en) * 2000-08-09 2005-09-20 Yale University Modulators of ribosomal function and identification thereof
US6638908B1 (en) 2000-08-09 2003-10-28 Yale University Crystals of the large ribosomal subunit
JP2004532972A (ja) 2000-12-09 2004-10-28 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア 転移ｒｎａおよびモデルメッセンジャーｒｎａに接触している機能的リボソーム複合体のｘ線結晶構造ならびにその使用方法
US6952650B2 (en) 2001-08-03 2005-10-04 Yale University Modulators of ribosomal function and identification thereof
IL151012A0 (en) 2001-08-03 2003-02-12 Ribosomes Structure And Protei Ribosomes structure and protein synthesis inhibitors
US8374794B1 (en) 2003-06-02 2013-02-12 Rib-X Pharmaceuticals, Inc. Protein synthesis modulators
US8428884B1 (en) 2003-07-14 2013-04-23 Rib-X Pharmaceuticals, Inc. Protein synthesis modulators
US20070118296A1 (en) * 2003-11-07 2007-05-24 Dna Software Inc. System and methods for three dimensional molecular structural analysis
US20070233539A1 (en) * 2006-03-30 2007-10-04 Philipp Suenderhauf Providing human capital management software application as enterprise services
US10556934B2 (en) 2015-01-29 2020-02-11 Yeda Research And Development Co. Ltd. Crystal structure of the large ribosomal subunit from S. aureus

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6093573A (en) * 1997-06-20 2000-07-25 Xoma Three-dimensional structure of bactericidal/permeability-increasing protein (BPI)
US6183121B1 (en) * 1997-08-14 2001-02-06 Vertex Pharmaceuticals Inc. Hepatitis C virus helicase crystals and coordinates that define helicase binding pockets
JP2004510681A (ja) * 1998-02-06 2004-04-08 イレクサス・ピーティーワイ・リミテッド Ｆｃ受容体の三次元構造およびモデル並びにその使用

Also Published As

Publication number Publication date
GB0029870D0 (en) 2001-01-24
GB0116858D0 (en) 2001-09-05
EP1172374A1 (de) 2002-01-16
CA2352399A1 (en) 2002-01-14
US20020106660A1 (en) 2002-08-08
AU7215701A (en) 2002-01-24
EP1172374A8 (de) 2004-09-08
GB0029871D0 (en) 2001-01-24
GB2368066B (en) 2004-11-10
EP1172374B1 (de) 2006-11-22
DE60124628T2 (de) 2007-09-13
DE60124628D1 (de) 2007-01-04
US6925394B2 (en) 2005-08-02
JP2005194188A (ja) 2005-07-21
GB2368066A (en) 2002-04-24
AU783778B2 (en) 2005-12-01
IL144083A0 (en) 2002-05-23

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