ATE345801T1 - Gatifloxacin als inhibitor der cytokinproduktion - Google Patents
Gatifloxacin als inhibitor der cytokinproduktionInfo
- Publication number
- ATE345801T1 ATE345801T1 AT01955609T AT01955609T ATE345801T1 AT E345801 T1 ATE345801 T1 AT E345801T1 AT 01955609 T AT01955609 T AT 01955609T AT 01955609 T AT01955609 T AT 01955609T AT E345801 T1 ATE345801 T1 AT E345801T1
- Authority
- AT
- Austria
- Prior art keywords
- gatifloxacin
- cytokine production
- inhibitor
- hydrate
- salt
- Prior art date
Links
- 230000016396 cytokine production Effects 0.000 title abstract 2
- 229960003923 gatifloxacin Drugs 0.000 title abstract 2
- 239000003112 inhibitor Substances 0.000 title abstract 2
- XUBOMFCQGDBHNK-UHFFFAOYSA-N gatifloxacin Chemical compound FC1=CC(C(C(C(O)=O)=CN2C3CC3)=O)=C2C(OC)=C1N1CCNC(C)C1 XUBOMFCQGDBHNK-UHFFFAOYSA-N 0.000 title 1
- XUBOMFCQGDBHNK-JTQLQIEISA-N (S)-gatifloxacin Chemical compound FC1=CC(C(C(C(O)=O)=CN2C3CC3)=O)=C2C(OC)=C1N1CCN[C@@H](C)C1 XUBOMFCQGDBHNK-JTQLQIEISA-N 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2000245831 | 2000-08-14 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE345801T1 true ATE345801T1 (de) | 2006-12-15 |
Family
ID=18736277
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT01955609T ATE345801T1 (de) | 2000-08-14 | 2001-08-09 | Gatifloxacin als inhibitor der cytokinproduktion |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20030176444A1 (de) |
| EP (1) | EP1312364B1 (de) |
| KR (1) | KR100771025B1 (de) |
| AT (1) | ATE345801T1 (de) |
| AU (1) | AU2001277725A1 (de) |
| CA (1) | CA2419178C (de) |
| DE (1) | DE60124732T2 (de) |
| ES (1) | ES2273872T3 (de) |
| TW (1) | TWI287987B (de) |
| WO (1) | WO2002013830A1 (de) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR0300521A (pt) * | 2003-03-13 | 2005-03-22 | Halex Star Ind Farmaceutica Lt | Processo de obtenção de solução isotÈnica injetável estável de gatifloxacina pré-diluìda em glicose, solução injetável estável de gatifloxacina pré-diluìda em glicose, processo de acondicionamento em sistema fechado da solução injetável obtida, uso de sistema fechado para acondicionamento de solução injetável de gatifloxacina, uso da solução injetável a base de gatifloxacina pré-diluìda em glicose obtida e método de administração |
| GB2400033A (en) * | 2003-03-29 | 2004-10-06 | Secr Defence | Use of fluoroquinolone antibiotics for the treatment of Q fever |
| CN1307995C (zh) * | 2005-10-12 | 2007-04-04 | 周卓和 | 加替沙星滴眼液及其制备方法 |
| US20100028328A1 (en) * | 2006-06-12 | 2010-02-04 | Therakine, Ltd. | Topical treatment for diseases of eye surface |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH089597B2 (ja) * | 1986-01-21 | 1996-01-31 | 杏林製薬株式会社 | 選択毒性に優れた８‐アルコキシキノロンカルボン酸およびその塩並びにその製造方法 |
| EP0355067A1 (de) * | 1988-08-19 | 1990-02-21 | Celltech Limited | Arzneimittel gegen bösartige Gewebeneubildung |
| DE69421694T2 (de) * | 1993-03-10 | 2000-05-25 | Otsuka Pharmaceutical Co., Ltd. | Interleukin-1 inhibitor |
| JP3449658B2 (ja) * | 1994-12-21 | 2003-09-22 | 杏林製薬株式会社 | 安定性に優れた８−アルコキシキノロンカルボン酸水和物並びにその製造方法 |
| US6010711A (en) * | 1996-01-26 | 2000-01-04 | University Of Rochester | Methods, articles and compositions for the pharmacologic inhibition of bone resorption with phosphodiesterase inhibitors |
| JPH10130149A (ja) * | 1996-07-12 | 1998-05-19 | Sankyo Co Ltd | Ｔｎｆ産生抑制剤 |
| JPH10130240A (ja) * | 1996-10-30 | 1998-05-19 | Dai Ichi Seiyaku Co Ltd | Ｉｃａｍ−１産生阻害剤 |
| SE9803710L (sv) * | 1998-09-25 | 2000-03-26 | A & Science Invest Ab | Användning av vissa substanser för behandling av nervrotsskador |
-
2001
- 2001-08-07 TW TW090119214A patent/TWI287987B/zh not_active IP Right Cessation
- 2001-08-09 ES ES01955609T patent/ES2273872T3/es not_active Expired - Lifetime
- 2001-08-09 KR KR1020037002149A patent/KR100771025B1/ko not_active IP Right Cessation
- 2001-08-09 AT AT01955609T patent/ATE345801T1/de not_active IP Right Cessation
- 2001-08-09 US US10/344,521 patent/US20030176444A1/en not_active Abandoned
- 2001-08-09 EP EP01955609A patent/EP1312364B1/de not_active Expired - Lifetime
- 2001-08-09 DE DE60124732T patent/DE60124732T2/de not_active Expired - Lifetime
- 2001-08-09 AU AU2001277725A patent/AU2001277725A1/en not_active Abandoned
- 2001-08-09 CA CA002419178A patent/CA2419178C/en not_active Expired - Fee Related
- 2001-08-09 WO PCT/JP2001/006839 patent/WO2002013830A1/ja active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| TWI287987B (en) | 2007-10-11 |
| EP1312364A1 (de) | 2003-05-21 |
| EP1312364B1 (de) | 2006-11-22 |
| US20030176444A1 (en) | 2003-09-18 |
| DE60124732T2 (de) | 2007-10-04 |
| CA2419178A1 (en) | 2003-02-13 |
| KR100771025B1 (ko) | 2007-10-29 |
| AU2001277725A1 (en) | 2002-02-25 |
| ES2273872T3 (es) | 2007-05-16 |
| WO2002013830A1 (fr) | 2002-02-21 |
| EP1312364A4 (de) | 2004-05-12 |
| DE60124732D1 (de) | 2007-01-04 |
| CA2419178C (en) | 2009-05-12 |
| KR20030024866A (ko) | 2003-03-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |