ATE329586T1 - COMPOSITIONS CONTAINING CAROTENOIDS AND THEIR USE FOR PREVENTING HORMONE-INDUCED SIDE EFFECTS - Google Patents

COMPOSITIONS CONTAINING CAROTENOIDS AND THEIR USE FOR PREVENTING HORMONE-INDUCED SIDE EFFECTS

Info

Publication number
ATE329586T1
ATE329586T1 AT01917436T AT01917436T ATE329586T1 AT E329586 T1 ATE329586 T1 AT E329586T1 AT 01917436 T AT01917436 T AT 01917436T AT 01917436 T AT01917436 T AT 01917436T AT E329586 T1 ATE329586 T1 AT E329586T1
Authority
AT
Austria
Prior art keywords
adverse effects
administration
hormone
side effects
preventing
Prior art date
Application number
AT01917436T
Other languages
German (de)
Inventor
Joseph Levy
Yoav Sharoni
Original Assignee
Lycored Natural Prod Ind Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lycored Natural Prod Ind Ltd filed Critical Lycored Natural Prod Ind Ltd
Application granted granted Critical
Publication of ATE329586T1 publication Critical patent/ATE329586T1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/01—Hydrocarbons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/01—Hydrocarbons
    • A61K31/015—Hydrocarbons carbocyclic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/07—Retinol compounds, e.g. vitamin A
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18—Feminine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/30—Oestrogens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Endocrinology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Mycology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Microbiology (AREA)
  • Rheumatology (AREA)
  • Medical Informatics (AREA)
  • Reproductive Health (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Urology & Nephrology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

A method for preventing the adverse effects which may he associated with the administration of at least one hormone to a subject without detectable cancer comprising administering to such subject at least one carotenoid. The method of the instant invention can be utilized to prevent a variety of adverse effects associated with the administration of hormones, including for example, an increased risk for developing cancer. The instantly claimed method prevents such adverse effects without inhibiting the beneficial activity of the hormone. Further provided by the present invention are compositions which are useful for preventing the adverse effects associated with the administration of hormones. The compositions of the instant invention may be in unit dosage form suitable for daily administration to a human.
AT01917436T 2000-03-29 2001-03-28 COMPOSITIONS CONTAINING CAROTENOIDS AND THEIR USE FOR PREVENTING HORMONE-INDUCED SIDE EFFECTS ATE329586T1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IL135335A IL135335A (en) 2000-03-29 2000-03-29 Use of carotenoids in the preparation of medicaments for preventing hormone induced adverse effects and pharmaceutical compositions comprising carotenoids

Publications (1)

Publication Number Publication Date
ATE329586T1 true ATE329586T1 (en) 2006-07-15

Family

ID=11073993

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01917436T ATE329586T1 (en) 2000-03-29 2001-03-28 COMPOSITIONS CONTAINING CAROTENOIDS AND THEIR USE FOR PREVENTING HORMONE-INDUCED SIDE EFFECTS

Country Status (16)

Country Link
US (4) US20010027216A1 (en)
EP (1) EP1267851B1 (en)
JP (1) JP5020455B2 (en)
KR (1) KR100818973B1 (en)
CN (1) CN1434707A (en)
AT (1) ATE329586T1 (en)
AU (2) AU4451101A (en)
BR (1) BR0107535A (en)
CA (1) CA2404097A1 (en)
DE (1) DE60120659T2 (en)
ES (1) ES2262635T3 (en)
IL (1) IL135335A (en)
NO (1) NO20024586L (en)
RU (1) RU2002125508A (en)
SE (1) SE0202857D0 (en)
WO (1) WO2001078701A2 (en)

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IL146449A0 (en) * 2001-11-12 2002-07-25 Lycored Natural Prod Ind Ltd Method and pharmaceutical preparations for reducing the activity of cells
JP2006516396A (en) * 2003-01-31 2006-07-06 デーエスエム アイピー アセッツ ベー． ヴェー． Novel compositions containing carotenoids
US20060247693A1 (en) 2005-04-28 2006-11-02 Yanting Dong Non-captured intrinsic discrimination in cardiac pacing response classification
US8521284B2 (en) 2003-12-12 2013-08-27 Cardiac Pacemakers, Inc. Cardiac response classification using multisite sensing and pacing
US7774064B2 (en) 2003-12-12 2010-08-10 Cardiac Pacemakers, Inc. Cardiac response classification using retriggerable classification windows
KR100739531B1 (en) 2004-05-07 2007-07-13 주식회사 이오텍 Compositions Comprising Lycopene and Phytoestrogen
US7706866B2 (en) 2004-06-24 2010-04-27 Cardiac Pacemakers, Inc. Automatic orientation determination for ECG measurements using multiple electrodes
JP2006069910A (en) * 2004-08-31 2006-03-16 Yoshiichi Sugimoto Anticancer agent-resistance overcoming agent
US7509170B2 (en) 2005-05-09 2009-03-24 Cardiac Pacemakers, Inc. Automatic capture verification using electrocardiograms sensed from multiple implanted electrodes
US7457664B2 (en) 2005-05-09 2008-11-25 Cardiac Pacemakers, Inc. Closed loop cardiac resynchronization therapy using cardiac activation sequence information
US7805185B2 (en) 2005-05-09 2010-09-28 Cardiac Pacemakers, In. Posture monitoring using cardiac activation sequences
US7890159B2 (en) 2004-09-30 2011-02-15 Cardiac Pacemakers, Inc. Cardiac activation sequence monitoring and tracking
US7797036B2 (en) 2004-11-30 2010-09-14 Cardiac Pacemakers, Inc. Cardiac activation sequence monitoring for ischemia detection
US7917196B2 (en) 2005-05-09 2011-03-29 Cardiac Pacemakers, Inc. Arrhythmia discrimination using electrocardiograms sensed from multiple implanted electrodes
US7392086B2 (en) 2005-04-26 2008-06-24 Cardiac Pacemakers, Inc. Implantable cardiac device and method for reduced phrenic nerve stimulation
US7901710B2 (en) 2005-08-04 2011-03-08 Vertical Pharmaceuticals, Inc. Nutritional supplement for use under physiologically stressful conditions
US7998500B2 (en) 2005-08-04 2011-08-16 Vertical Pharmaceuticals, Inc. Nutritional supplement for women
US8202546B2 (en) 2005-08-04 2012-06-19 Vertical Pharmaceuticals, Inc. Nutritional supplement for use under physiologically stressful conditions
US8263137B2 (en) 2005-08-04 2012-09-11 Vertical Pharmaceuticals, Inc. Nutritional supplement for women
US8527048B2 (en) 2006-06-29 2013-09-03 Cardiac Pacemakers, Inc. Local and non-local sensing for cardiac pacing
US20080004665A1 (en) * 2006-06-29 2008-01-03 Mccabe Aaron R Determination of cardiac pacing parameters based on non-localized sensing
US8209013B2 (en) 2006-09-14 2012-06-26 Cardiac Pacemakers, Inc. Therapeutic electrical stimulation that avoids undesirable activation
US9037239B2 (en) 2007-08-07 2015-05-19 Cardiac Pacemakers, Inc. Method and apparatus to perform electrode combination selection
US8265736B2 (en) 2007-08-07 2012-09-11 Cardiac Pacemakers, Inc. Method and apparatus to perform electrode combination selection
AU2009214920B2 (en) 2008-02-14 2012-02-09 Cardiac Pacemakers, Inc. Method and apparatus for phrenic stimulation detection
WO2010042364A2 (en) 2008-10-06 2010-04-15 Cardiac Pacemakers, Inc. Dynamic cardiac resynchronization therapy by tracking intrinsic conduction
PT2782584T (en) 2011-11-23 2021-09-02 Therapeuticsmd Inc Natural combination hormone replacement formulations and therapies
US9301920B2 (en) 2012-06-18 2016-04-05 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
US10806740B2 (en) 2012-06-18 2020-10-20 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
US20130338122A1 (en) 2012-06-18 2013-12-19 Therapeuticsmd, Inc. Transdermal hormone replacement therapies
US10806697B2 (en) 2012-12-21 2020-10-20 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US20150196640A1 (en) 2012-06-18 2015-07-16 Therapeuticsmd, Inc. Progesterone formulations having a desirable pk profile
US11266661B2 (en) 2012-12-21 2022-03-08 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10568891B2 (en) 2012-12-21 2020-02-25 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US9180091B2 (en) 2012-12-21 2015-11-10 Therapeuticsmd, Inc. Soluble estradiol capsule for vaginal insertion
US10537581B2 (en) 2012-12-21 2020-01-21 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US11246875B2 (en) 2012-12-21 2022-02-15 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10471072B2 (en) 2012-12-21 2019-11-12 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
JP2017516768A (en) 2014-05-22 2017-06-22 セラピューティックスエムディー インコーポレーテッドＴｈｅｒａｐｅｕｔｉｃｓｍｄ， Ｉｎｃ． Natural combination hormone replacement therapy and therapy
US10328087B2 (en) 2015-07-23 2019-06-25 Therapeuticsmd, Inc. Formulations for solubilizing hormones
US9669006B2 (en) 2015-07-28 2017-06-06 U.S. Nutraceuticals, LLC Composition and method to treat and alleviate symptoms of hot flashes in a female subject
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Also Published As

Publication number Publication date
ES2262635T3 (en) 2006-12-01
EP1267851A2 (en) 2003-01-02
WO2001078701A3 (en) 2002-07-25
EP1267851B1 (en) 2006-06-14
KR20020093858A (en) 2002-12-16
NO20024586D0 (en) 2002-09-25
JP2003530428A (en) 2003-10-14
JP5020455B2 (en) 2012-09-05
KR100818973B1 (en) 2008-04-04
SE0202857D0 (en) 2002-09-27
DE60120659T2 (en) 2007-06-06
US20030148946A1 (en) 2003-08-07
IL135335A (en) 2013-12-31
US20030004146A1 (en) 2003-01-02
IL135335A0 (en) 2001-05-20
US20040198674A1 (en) 2004-10-07
CN1434707A (en) 2003-08-06
DE60120659D1 (en) 2006-07-27
US7144586B2 (en) 2006-12-05
CA2404097A1 (en) 2001-10-25
AU4451101A (en) 2001-10-30
US8669293B2 (en) 2014-03-11
AU2001244511B2 (en) 2006-04-27
BR0107535A (en) 2005-05-03
WO2001078701A2 (en) 2001-10-25
RU2002125508A (en) 2004-03-20
US20010027216A1 (en) 2001-10-04
NO20024586L (en) 2002-11-25

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