ATE328T1 - 1-DESOXYNOJIRIMYCIN MANUFACTURE. - Google Patents

1-DESOXYNOJIRIMYCIN MANUFACTURE.

Info

Publication number
ATE328T1
ATE328T1 AT80100552T AT80100552T ATE328T1 AT E328 T1 ATE328 T1 AT E328T1 AT 80100552 T AT80100552 T AT 80100552T AT 80100552 T AT80100552 T AT 80100552T AT E328 T1 ATE328 T1 AT E328T1
Authority
AT
Austria
Prior art keywords
desoxynojirimycin
manufacture
nutrient solution
organism
isolating
Prior art date
Application number
AT80100552T
Other languages
German (de)
Inventor
Werner Dr. Frommer
Delf Dr. Schmidt
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Application granted granted Critical
Publication of ATE328T1 publication Critical patent/ATE328T1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/10—Nitrogen as only ring hetero atom
    • C12P17/12—Nitrogen as only ring hetero atom containing a six-membered hetero ring
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/832—Bacillus
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/832—Bacillus
    • Y10S435/838—Bacillus polymyxa
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/832—Bacillus
    • Y10S435/839—Bacillus subtilis

Abstract

The invention relates to a novel process for the production of 1-desoxynojirimycin which involves culturing an organism of the Bacillaceae family in a nutrient solution as a temperature of about 15 DEG to 80 DEG C. in a fermentation vessel, whilst aerating and then isolating the 1-desoxynojirimycin, said nutrient solution containing sorbitol as the source of carbon.
AT80100552T 1979-02-23 1980-02-04 1-DESOXYNOJIRIMYCIN MANUFACTURE. ATE328T1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19792907190 DE2907190A1 (en) 1979-02-23 1979-02-23 1-DESOXYNOJIRIMYCIN PRODUCTION
EP80100552A EP0015388B1 (en) 1979-02-23 1980-02-04 Preparation of 1-desoxynojirimycin

Publications (1)

Publication Number Publication Date
ATE328T1 true ATE328T1 (en) 1981-11-15

Family

ID=6063797

Family Applications (1)

Application Number Title Priority Date Filing Date
AT80100552T ATE328T1 (en) 1979-02-23 1980-02-04 1-DESOXYNOJIRIMYCIN MANUFACTURE.

Country Status (7)

Country Link
US (1) US4282320A (en)
EP (1) EP0015388B1 (en)
JP (1) JPS55114294A (en)
AT (1) ATE328T1 (en)
DE (2) DE2907190A1 (en)
DK (1) DK147453C (en)
ES (1) ES488865A1 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5256788A (en) * 1989-02-13 1993-10-26 Nippon Shinyaku Co. Ltd. Moranoline derivatives and their production and the use of moranoline and its derivatives as a stabilizing agent for enzymes
DK0477160T3 (en) * 1990-09-20 1996-05-20 Monsanto Co Process for the preparation of N-substituted 1-deoxynojirimycin
KR102387028B1 (en) * 2020-10-06 2022-04-14 이해익 A novel Bacillus coagulans CC strain having high productivity for alpha glucosidase inhibitor
CN113637605B (en) * 2021-08-09 2023-05-05 浙江珲达生物科技有限公司 Bacillus amyloliquefaciens and application thereof in preparation of 1-deoxynojirimycin
CN115806913B (en) * 2022-10-21 2023-09-08 福建省农业科学院植物保护研究所 Streptomyces nojirimensis (Streptomyces nojiriensis) strain 9-13 and application thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3634197A (en) * 1966-11-07 1972-01-11 Sumio Umezawa Production of 3-amino-3-deoxy-d-glucose
US3998698A (en) * 1976-04-08 1976-12-21 The Upjohn Company Process for producing antibiotic U-51,640
DE2726899A1 (en) * 1977-06-15 1979-04-12 Bayer Ag Glucoside hydrolase inhibitors prodn. from bacteria - esp. Bacillus species useful, e.g., for increasing meat yields and feed efficiency
DE2658563A1 (en) * 1976-12-23 1978-06-29 Bayer Ag Glucoside hydrolase inhibitors prodn. from bacteria - esp. Bacillus species useful, e.g., for increasing meat yields and feed efficiency
US4307194A (en) * 1976-12-23 1981-12-22 Bayer Aktiengesellschaft Inhibitors, obtained from bacilli, for glycoside hydrolases

Also Published As

Publication number Publication date
JPS6328599B2 (en) 1988-06-09
US4282320A (en) 1981-08-04
DE2907190A1 (en) 1980-08-28
DK77180A (en) 1980-08-24
DK147453B (en) 1984-08-13
ES488865A1 (en) 1980-09-16
JPS55114294A (en) 1980-09-03
DK147453C (en) 1985-05-28
EP0015388B1 (en) 1981-10-21
DE3060037D1 (en) 1981-12-24
EP0015388A1 (en) 1980-09-17

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Legal Events

Date Code Title Description
REN Ceased due to non-payment of the annual fee