ATE319819T1 - Humane hirn-spezifische carboxypeptidase b - Google Patents

Humane hirn-spezifische carboxypeptidase b

Info

Publication number
ATE319819T1
ATE319819T1 AT00922936T AT00922936T ATE319819T1 AT E319819 T1 ATE319819 T1 AT E319819T1 AT 00922936 T AT00922936 T AT 00922936T AT 00922936 T AT00922936 T AT 00922936T AT E319819 T1 ATE319819 T1 AT E319819T1
Authority
AT
Austria
Prior art keywords
human brain
specific carboxypeptidase
carboxypeptidase
specific
gene
Prior art date
Application number
AT00922936T
Other languages
English (en)
Inventor
Akira Matsumoto
Original Assignee
Akira Matsumoto
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akira Matsumoto filed Critical Akira Matsumoto
Application granted granted Critical
Publication of ATE319819T1 publication Critical patent/ATE319819T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4711—Alzheimer's disease; Amyloid plaque core protein
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
    • G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
    • G01N2333/4701—Details
    • G01N2333/4709—Amyloid plaque core protein
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/28—Neurological disorders
    • G01N2800/2814—Dementia; Cognitive disorders
    • G01N2800/2821—Alzheimer

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Neurology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Hydrogenated Pyridines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
AT00922936T 1999-04-30 2000-05-01 Humane hirn-spezifische carboxypeptidase b ATE319819T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP12516999 1999-04-30

Publications (1)

Publication Number Publication Date
ATE319819T1 true ATE319819T1 (de) 2006-03-15

Family

ID=14903603

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00922936T ATE319819T1 (de) 1999-04-30 2000-05-01 Humane hirn-spezifische carboxypeptidase b

Country Status (8)

Country Link
US (3) US7060266B1 (de)
EP (1) EP1179588B9 (de)
JP (1) JP4579422B2 (de)
AT (1) ATE319819T1 (de)
AU (1) AU4316600A (de)
DE (1) DE60026501T2 (de)
ES (1) ES2260011T3 (de)
WO (1) WO2000066717A1 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7060266B1 (en) 1999-04-30 2006-06-13 Akira Matsumoto Human brain carboxypeptidase B
US6455294B1 (en) * 2001-03-21 2002-09-24 Applera Corporation Isolated human protease proteins, nucleic acid molecules encoding human protease proteins, and uses thereof
US7291587B2 (en) 2001-11-09 2007-11-06 Novo Nordisk Healthcare A/G Pharmaceutical composition comprising factor VII polypeptides and TAFI polypeptides
WO2003076572A2 (en) 2002-03-04 2003-09-18 Bristol-Myers Squibb Company Novel nucleic acid molecules and polypeptides encoding baboon tafi
EP1380290A1 (de) * 2002-07-09 2004-01-14 Universitair Medisch Centrum Utrecht Cross-Beta-Strukturweg und seine therapeutische Relevanz
EP1794294B1 (de) * 2004-09-27 2011-07-20 Sanofi-Aventis Deutschland GmbH Rekombinante carboxypeptidase b
US7807789B2 (en) * 2004-12-21 2010-10-05 Cell Signaling Technology, Inc. Reagents for the detection of protein phosphorylation in EGFR-signaling pathways
US8114832B2 (en) 2005-07-13 2012-02-14 Crossbeta Biosciences B.V. Method for detecting and/or removing a protein comprising a cross-beta structure from a pharmaceutical composition
AU2006267176A1 (en) 2005-07-13 2007-01-18 Crossbeta Biosciences B.V. Cross-beta structure binding compounds
KR100851035B1 (ko) * 2005-08-23 2008-08-11 대한민국 ＧＣＰ-Ⅱ를 유효성분으로 함유하는 β-아밀로이드의 뇌내축적 예방 및 치료용 약학적 조성물과 치료제 스크리닝용조성물 및 이를 이용한 스크리닝 방법
JP5775356B2 (ja) * 2011-05-09 2015-09-09 松本　明 神経保護作用を有するペプチド及びこれを含む薬剤
US8877446B2 (en) * 2011-08-26 2014-11-04 Korea Research Institute Of Bioscience And Biotechnology Method for detecting protein-protein interactions in cells

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5206161A (en) * 1991-02-01 1993-04-27 Genentech, Inc. Human plasma carboxypeptidase B
US5985562A (en) 1997-06-03 1999-11-16 Schering Aktiengesellschaft Method of detecting thrombotic disease risk associated with plasma carboxypeptidase B polymorphisms
US7060266B1 (en) 1999-04-30 2006-06-13 Akira Matsumoto Human brain carboxypeptidase B

Also Published As

Publication number Publication date
DE60026501T2 (de) 2006-08-10
AU4316600A (en) 2000-11-17
DE60026501D1 (en) 2006-05-04
ES2260011T3 (es) 2006-11-01
EP1179588A1 (de) 2002-02-13
US20100021951A1 (en) 2010-01-28
US7524934B2 (en) 2009-04-28
US20060024760A1 (en) 2006-02-02
JP4579422B2 (ja) 2010-11-10
WO2000066717A1 (fr) 2000-11-09
EP1179588B1 (de) 2006-03-08
EP1179588A4 (de) 2004-04-07
US7060266B1 (en) 2006-06-13
EP1179588B9 (de) 2006-07-19
US7972771B2 (en) 2011-07-05

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Legal Events

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