ATE319105T1 - Nmr-verfahren zur bestimmung des risikos zur entwicklung von diabetes type 2 - Google Patents

Nmr-verfahren zur bestimmung des risikos zur entwicklung von diabetes type 2

Info

Publication number
ATE319105T1
ATE319105T1 AT00926111T AT00926111T ATE319105T1 AT E319105 T1 ATE319105 T1 AT E319105T1 AT 00926111 T AT00926111 T AT 00926111T AT 00926111 T AT00926111 T AT 00926111T AT E319105 T1 ATE319105 T1 AT E319105T1
Authority
AT
Austria
Prior art keywords
nmr
diabetes
patient
glucose concentration
lipoprotein
Prior art date
Application number
AT00926111T
Other languages
German (de)
English (en)
Inventor
James D Otvos
Dennis W Bennett
Original Assignee
Liposcience Inc
Univ North Carolina State
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Liposcience Inc, Univ North Carolina State filed Critical Liposcience Inc
Application granted granted Critical
Publication of ATE319105T1 publication Critical patent/ATE319105T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/66—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood sugars, e.g. galactose
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/20—Arrangements or instruments for measuring magnetic variables involving magnetic resonance
    • G01R33/44—Arrangements or instruments for measuring magnetic variables involving magnetic resonance using nuclear magnetic resonance [NMR]
    • G01R33/46—NMR spectroscopy
    • G01R33/465—NMR spectroscopy applied to biological material, e.g. in vitro testing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N24/00—Investigating or analyzing materials by the use of nuclear magnetic resonance, electron paramagnetic resonance or other spin effects
    • G01N24/08—Investigating or analyzing materials by the use of nuclear magnetic resonance, electron paramagnetic resonance or other spin effects by using nuclear magnetic resonance
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2405/00—Assays, e.g. immunoassays or enzyme assays, involving lipids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/04—Endocrine or metabolic disorders
    • G01N2800/042—Disorders of carbohydrate metabolism, e.g. diabetes, glucose metabolism
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/32—Cardiovascular disorders
    • G01N2800/324—Coronary artery diseases, e.g. angina pectoris, myocardial infarction
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/14—Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/142222—Hetero-O [e.g., ascorbic acid, etc.]
    • Y10T436/143333—Saccharide [e.g., DNA, etc.]
    • Y10T436/144444—Glucose
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/24—Nuclear magnetic resonance, electron spin resonance or other spin effects or mass spectrometry

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Pathology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • High Energy & Nuclear Physics (AREA)
  • Condensed Matter Physics & Semiconductors (AREA)
  • Endocrinology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
AT00926111T 1999-04-22 2000-04-19 Nmr-verfahren zur bestimmung des risikos zur entwicklung von diabetes type 2 ATE319105T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US13061299P 1999-04-22 1999-04-22

Publications (1)

Publication Number Publication Date
ATE319105T1 true ATE319105T1 (de) 2006-03-15

Family

ID=22445506

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00926111T ATE319105T1 (de) 1999-04-22 2000-04-19 Nmr-verfahren zur bestimmung des risikos zur entwicklung von diabetes type 2

Country Status (9)

Country Link
US (1) US6518069B1 (cg-RX-API-DMAC7.html)
EP (1) EP1171778B1 (cg-RX-API-DMAC7.html)
JP (1) JP4585693B2 (cg-RX-API-DMAC7.html)
AT (1) ATE319105T1 (cg-RX-API-DMAC7.html)
AU (1) AU4469300A (cg-RX-API-DMAC7.html)
CA (1) CA2367820C (cg-RX-API-DMAC7.html)
DE (1) DE60026287T2 (cg-RX-API-DMAC7.html)
ES (1) ES2256000T3 (cg-RX-API-DMAC7.html)
WO (1) WO2000065366A1 (cg-RX-API-DMAC7.html)

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US20040142496A1 (en) 2001-04-23 2004-07-22 Nicholson Jeremy Kirk Methods for analysis of spectral data and their applications: atherosclerosis/coronary heart disease
CA2445106A1 (en) * 2001-04-23 2002-10-31 Metabometrix Limited Methods for analysis of spectral data and their applications: osteoporosis
US20040142403A1 (en) * 2001-08-13 2004-07-22 Donald Hetzel Method of screening for disorders of glucose metabolism
EP1444526B1 (en) 2001-11-13 2011-09-21 The Regents of The University of California Ion mobility analysis of biological particles
EP1481356A1 (en) 2001-11-21 2004-12-01 Paradigm Genetics Inc. Methods and systems for analyzing complex biological systems
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US20070011049A1 (en) * 2005-07-09 2007-01-11 Eder Jeffrey S Intelligent, personalized commerce chain
WO2004040407A2 (en) * 2002-10-25 2004-05-13 Liposcience, Inc. Methods, systems and computer programs for deconvolving the spectral contribution of chemical constituents with overlapping signals
DE10315877B4 (de) 2003-04-08 2005-11-17 Roche Diagnostics Gmbh Krankheitsverlaufkontrolle
US8460243B2 (en) * 2003-06-10 2013-06-11 Abbott Diabetes Care Inc. Glucose measuring module and insulin pump combination
US7722536B2 (en) * 2003-07-15 2010-05-25 Abbott Diabetes Care Inc. Glucose measuring device integrated into a holster for a personal area network device
US7197427B2 (en) * 2004-03-31 2007-03-27 Genworth Financial Inc. Method for risk based testing
EP2189802B1 (en) * 2004-04-01 2014-05-14 Liposcience, Inc. NMR clinical analyzers and related methods, systems, modules and computer program products for clinical evaluation biosamples
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US7951078B2 (en) * 2005-02-03 2011-05-31 Maren Theresa Scheuner Method and apparatus for determining familial risk of disease
DE502006001913D1 (de) 2005-03-15 2008-12-11 Roche Diagnostics Gmbh Verfahren und System zur Untersuchung des Glucosestoffwechsels
US8216848B2 (en) * 2006-03-24 2012-07-10 Metanomics Gmbh Means and method for diagnosing diabetes
US8498915B2 (en) * 2006-04-02 2013-07-30 Asset Reliance, Inc. Data processing framework for financial services
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US9250211B2 (en) 2010-12-30 2016-02-02 Quest Diagnostics Investments Incorporated Magnetic separation of lipoproteins using dextran sulfate
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US9689942B2 (en) 2011-06-30 2017-06-27 Liposcience, Inc. Quantitative NMR clinical analyzers with automatic NMR temperature sensitivity compensation that accommodate large ambient operational temperature ranges
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US9361429B2 (en) 2012-06-08 2016-06-07 Liposcience, Inc. Multi-parameter diabetes risk evaluations
US9928345B2 (en) 2012-06-08 2018-03-27 Liposciences, Inc. Multiple-marker risk parameters predictive of conversion to diabetes
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Also Published As

Publication number Publication date
DE60026287T2 (de) 2006-08-17
WO2000065366A1 (en) 2000-11-02
EP1171778A1 (en) 2002-01-16
EP1171778B1 (en) 2006-03-01
ES2256000T3 (es) 2006-07-16
US6518069B1 (en) 2003-02-11
CA2367820A1 (en) 2000-11-02
WO2000065366A8 (en) 2001-03-29
CA2367820C (en) 2009-12-22
DE60026287D1 (de) 2006-04-27
JP4585693B2 (ja) 2010-11-24
JP2002543392A (ja) 2002-12-17
AU4469300A (en) 2000-11-10

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