ATE317546T1 - Verfahren zur messung des aktivierungszustands von signalwegen in zellen - Google Patents
Verfahren zur messung des aktivierungszustands von signalwegen in zellenInfo
- Publication number
- ATE317546T1 ATE317546T1 AT01997685T AT01997685T ATE317546T1 AT E317546 T1 ATE317546 T1 AT E317546T1 AT 01997685 T AT01997685 T AT 01997685T AT 01997685 T AT01997685 T AT 01997685T AT E317546 T1 ATE317546 T1 AT E317546T1
- Authority
- AT
- Austria
- Prior art keywords
- reporter
- amount
- cell
- enzyme
- cells
- Prior art date
Links
- 230000004913 activation Effects 0.000 title 1
- 230000019491 signal transduction Effects 0.000 title 1
- 102000004190 Enzymes Human genes 0.000 abstract 4
- 108090000790 Enzymes Proteins 0.000 abstract 4
- 230000000694 effects Effects 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 2
- 102000004169 proteins and genes Human genes 0.000 abstract 2
- 108090000623 proteins and genes Proteins 0.000 abstract 2
- 230000007248 cellular mechanism Effects 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 230000003292 diminished effect Effects 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 238000009509 drug development Methods 0.000 abstract 1
- 238000007877 drug screening Methods 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
-
- G01N15/1433—
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/02—Devices for withdrawing samples
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US25286100P | 2000-11-22 | 2000-11-22 |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE317546T1 true ATE317546T1 (de) | 2006-02-15 |
Family
ID=22957857
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT01997685T ATE317546T1 (de) | 2000-11-22 | 2001-11-21 | Verfahren zur messung des aktivierungszustands von signalwegen in zellen |
Country Status (6)
Country | Link |
---|---|
EP (1) | EP1336101B1 (de) |
JP (1) | JP2004514885A (de) |
AT (1) | ATE317546T1 (de) |
AU (1) | AU2002217839A1 (de) |
DE (1) | DE60117180T2 (de) |
WO (1) | WO2002042732A2 (de) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6740497B2 (en) * | 1998-03-06 | 2004-05-25 | The Regents Of The University Of California | Method and apparatus for detecting cancerous cells using molecules that change electrophoretic mobility |
US6335201B1 (en) | 1998-03-06 | 2002-01-01 | The Regents Of The University Of California | Method and apparatus for detecting enzymatic activity using molecules that change electrophoretic mobility |
US7183066B2 (en) * | 2002-09-27 | 2007-02-27 | Allergan, Inc. | Cell-based fluorescence resonance energy transfer (FRET) assays for clostridial toxins |
DE102005059536B4 (de) * | 2005-12-13 | 2008-08-28 | Siemens Ag | Verfahren und Biochip zur Untersuchung einer biologischen Probe |
WO2009100028A1 (en) * | 2008-02-01 | 2009-08-13 | The Regents Of The University Of California | Microfluidic imaging cytometry |
CN101231262B (zh) * | 2008-02-22 | 2011-09-14 | 东南大学 | 用于单细胞组学的方法 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5258289A (en) * | 1990-09-05 | 1993-11-02 | Davis Claude G | Method for the selecting of genes encoding catalytic antibodies |
US5156576B1 (en) * | 1991-05-22 | 1994-08-30 | Sauer Inc | Compact integrated transaxle |
US5958703A (en) * | 1996-12-03 | 1999-09-28 | Glaxo Group Limited | Use of modified tethers in screening compound libraries |
US6156576A (en) * | 1998-03-06 | 2000-12-05 | The Regents Of The University Of California | Fast controllable laser lysis of cells for analysis |
US6335201B1 (en) * | 1998-03-06 | 2002-01-01 | The Regents Of The University Of California | Method and apparatus for detecting enzymatic activity using molecules that change electrophoretic mobility |
EP1121593A2 (de) * | 1998-10-15 | 2001-08-08 | BioImage A/S | Verfahren zur ableitung quantitativer informationen über einen einfluss auf eine zelluläre respons |
WO2000050872A2 (en) * | 1999-02-26 | 2000-08-31 | Cellomics, Inc. | A system for cell-based screening |
AU2579401A (en) * | 1999-12-17 | 2001-06-25 | Johns Hopkins University, The | Brain protein markers |
-
2001
- 2001-11-21 JP JP2002544624A patent/JP2004514885A/ja not_active Withdrawn
- 2001-11-21 EP EP01997685A patent/EP1336101B1/de not_active Expired - Lifetime
- 2001-11-21 AU AU2002217839A patent/AU2002217839A1/en not_active Abandoned
- 2001-11-21 DE DE60117180T patent/DE60117180T2/de not_active Expired - Fee Related
- 2001-11-21 AT AT01997685T patent/ATE317546T1/de not_active IP Right Cessation
- 2001-11-21 WO PCT/US2001/043966 patent/WO2002042732A2/en active Search and Examination
Also Published As
Publication number | Publication date |
---|---|
DE60117180T2 (de) | 2006-08-10 |
JP2004514885A (ja) | 2004-05-20 |
AU2002217839A1 (en) | 2002-06-03 |
DE60117180D1 (de) | 2006-04-20 |
EP1336101B1 (de) | 2006-02-08 |
EP1336101A2 (de) | 2003-08-20 |
WO2002042732A3 (en) | 2002-08-01 |
EP1336101A4 (de) | 2004-08-18 |
WO2002042732A2 (en) | 2002-05-30 |
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Legal Events
Date | Code | Title | Description |
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RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |