ATE315335T1 - Indolocarbazol-antikrebsmittel und verfahren zu ihrer verwendung - Google Patents

Indolocarbazol-antikrebsmittel und verfahren zu ihrer verwendung

Info

Publication number
ATE315335T1
ATE315335T1 AT01989340T AT01989340T ATE315335T1 AT E315335 T1 ATE315335 T1 AT E315335T1 AT 01989340 T AT01989340 T AT 01989340T AT 01989340 T AT01989340 T AT 01989340T AT E315335 T1 ATE315335 T1 AT E315335T1
Authority
AT
Austria
Prior art keywords
indolocarbazole
anticancer agents
relates
compositions
activity
Prior art date
Application number
AT01989340T
Other languages
English (en)
Inventor
David E Zembower
Yongping Xie
Yasheen Zhou
Original Assignee
Advanced Life Sciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Advanced Life Sciences Inc filed Critical Advanced Life Sciences Inc
Application granted granted Critical
Publication of ATE315335T1 publication Critical patent/ATE315335T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/044Pyrrole radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AT01989340T 2000-10-31 2001-10-29 Indolocarbazol-antikrebsmittel und verfahren zu ihrer verwendung ATE315335T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US24446900P 2000-10-31 2000-10-31

Publications (1)

Publication Number Publication Date
ATE315335T1 true ATE315335T1 (de) 2006-02-15

Family

ID=22922901

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01989340T ATE315335T1 (de) 2000-10-31 2001-10-29 Indolocarbazol-antikrebsmittel und verfahren zu ihrer verwendung

Country Status (8)

Country Link
US (1) US6605596B2 (de)
EP (1) EP1341412B1 (de)
JP (1) JP4060709B2 (de)
AT (1) ATE315335T1 (de)
AU (2) AU4344202A (de)
CA (1) CA2426754C (de)
DE (1) DE60116664T2 (de)
WO (1) WO2002048166A1 (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE255122T1 (de) 2000-02-24 2003-12-15 Banyu Pharma Co Ltd Verfahren zur herstellung von indolopyrrolocarbazol-derivaten, deren zwischenprodukte sowie verfahren zur herstellung der zwischenprodukte
US7122526B2 (en) * 2000-10-31 2006-10-17 Nanosphere, Inc. Indolocarbazole anticancer agents and methods of using same
KR101413988B1 (ko) * 2012-04-25 2014-07-01 (주)이스트소프트 문서의 이산분리시스템 및 방법

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5106742A (en) 1987-03-31 1992-04-21 Wall Monroe E Camptothecin analogs as potent inhibitors of topoisomerase I
US5364858A (en) 1987-03-31 1994-11-15 Research Triangle Institute Camptothecin analogs as potent inhibitors of topoisomerase I
US5559235A (en) 1991-10-29 1996-09-24 Glaxo Wellcome Inc. Water soluble camptothecin derivatives
US5668271A (en) 1991-11-29 1997-09-16 Banyu Pharmaceutical Co., Ltd. Indolopyrrolocarbazole derivatives
US5591842A (en) 1991-11-29 1997-01-07 Banyu Pharmaceutical Co., Ltd. Indolopyrrolocarbazole derivatives
US5437996A (en) 1992-11-24 1995-08-01 Banyu Pharmaceutical Co., Ltd. Microtetraspora strain for preparation of indolopyrrolocarbazole derivatives
US5589365A (en) 1991-11-29 1996-12-31 Banyu Pharmaceutical Co., Ltd. Process for producing glycosylated indolopyrrolocarbazole derivatives by culturing certain microorganisms
DE4217964A1 (de) 1992-05-30 1993-12-02 Goedecke Ag Indolocarbazol-Imide und deren Verwendung
US5922860A (en) 1994-05-09 1999-07-13 Banyu Pharmaceutical Co., Ltd. Antitumor indolopyrrolocarbazole derivatives
US5804564A (en) 1994-05-09 1998-09-08 Banyu Pharmaceutical Co., Ltd. Antitumor indolopyrrolocarbazole derivatives
WO1996004293A1 (fr) 1994-08-02 1996-02-15 Banyu Pharmaceutical Co., Ltd. Indolopyrrolocarbazoles antitumoraux
WO1997009339A1 (fr) 1995-09-05 1997-03-13 Banyu Pharmaceutical Co., Ltd. Derives antitumoraux d'indolopyrrolocarbazole
US5859261A (en) 1997-03-20 1999-01-12 Eli Lilly And Company Synthesis of indolylmaleimides

Also Published As

Publication number Publication date
CA2426754A1 (en) 2002-06-20
US20030087842A1 (en) 2003-05-08
JP4060709B2 (ja) 2008-03-12
CA2426754C (en) 2008-03-25
DE60116664D1 (de) 2006-04-06
JP2004515554A (ja) 2004-05-27
EP1341412A1 (de) 2003-09-10
EP1341412B1 (de) 2006-01-11
US6605596B2 (en) 2003-08-12
DE60116664T2 (de) 2006-09-07
AU2002243442B2 (en) 2004-11-04
WO2002048166A1 (en) 2002-06-20
WO2002048166A8 (en) 2003-01-03
AU4344202A (en) 2002-06-24

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Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties