ATE315106T1 - Systeme und verfahren zum sequenzieren durch hybridation - Google Patents

Systeme und verfahren zum sequenzieren durch hybridation

Info

Publication number
ATE315106T1
ATE315106T1 AT99970428T AT99970428T ATE315106T1 AT E315106 T1 ATE315106 T1 AT E315106T1 AT 99970428 T AT99970428 T AT 99970428T AT 99970428 T AT99970428 T AT 99970428T AT E315106 T1 ATE315106 T1 AT E315106T1
Authority
AT
Austria
Prior art keywords
probes
sequencing
gapped
systems
relate
Prior art date
Application number
AT99970428T
Other languages
English (en)
Inventor
Franco P Preparata
Eli Upfal
Original Assignee
Univ Brown Res Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Brown Res Found filed Critical Univ Brown Res Found
Application granted granted Critical
Publication of ATE315106T1 publication Critical patent/ATE315106T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing
    • C12Q1/6874—Methods for sequencing involving nucleic acid arrays, e.g. sequencing by hybridisation

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
AT99970428T 1998-10-13 1999-10-13 Systeme und verfahren zum sequenzieren durch hybridation ATE315106T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10399898P 1998-10-13 1998-10-13
US12570499P 1999-03-23 1999-03-23

Publications (1)

Publication Number Publication Date
ATE315106T1 true ATE315106T1 (de) 2006-02-15

Family

ID=26801084

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99970428T ATE315106T1 (de) 1998-10-13 1999-10-13 Systeme und verfahren zum sequenzieren durch hybridation

Country Status (5)

Country Link
EP (1) EP1121472B1 (de)
AT (1) ATE315106T1 (de)
AU (1) AU1204600A (de)
DE (1) DE69929365T2 (de)
WO (1) WO2000022171A2 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7071324B2 (en) 1998-10-13 2006-07-04 Brown University Research Foundation Systems and methods for sequencing by hybridization
US6949340B2 (en) * 2001-03-28 2005-09-27 Creative Mines Llc Optical phase modulator
WO2002090599A1 (en) 2001-05-09 2002-11-14 Genetic Id, Inc. Universal microarray system
EP1442137A4 (de) 2001-11-07 2005-08-31 Applera Corp Universelle nukleotide für die nukleinsäureanalyse
WO2009046094A1 (en) 2007-10-01 2009-04-09 Nabsys, Inc. Biopolymer sequencing by hybridization of probes to form ternary complexes and variable range alignment
US9650668B2 (en) 2008-09-03 2017-05-16 Nabsys 2.0 Llc Use of longitudinally displaced nanoscale electrodes for voltage sensing of biomolecules and other analytes in fluidic channels
JP5717634B2 (ja) 2008-09-03 2015-05-13 ナブシス， インコーポレイテッド 流体チャネル内の生体分子および他の分析物の電圧感知のための、長手方向に変位されるナノスケールの電極の使用
US8262879B2 (en) 2008-09-03 2012-09-11 Nabsys, Inc. Devices and methods for determining the length of biopolymers and distances between probes bound thereto
US8715933B2 (en) 2010-09-27 2014-05-06 Nabsys, Inc. Assay methods using nicking endonucleases
JP5998148B2 (ja) 2010-11-16 2016-09-28 ナブシス ２．０ エルエルシー ハイブリダイズされたプローブの相対位置を検出することによる生体分子のシークエンシングのための方法
US11274341B2 (en) 2011-02-11 2022-03-15 NABsys, 2.0 LLC Assay methods using DNA binding proteins
US9914966B1 (en) 2012-12-20 2018-03-13 Nabsys 2.0 Llc Apparatus and methods for analysis of biomolecules using high frequency alternating current excitation
US10294516B2 (en) 2013-01-18 2019-05-21 Nabsys 2.0 Llc Enhanced probe binding
US11708605B2 (en) * 2019-11-06 2023-07-25 Adaptive Biotechnologies Corporation Synthetic strands for nucleic acid sequencing and related methods and systems
CN115551639A (zh) * 2020-04-21 2022-12-30 赫孚孟拉罗股份公司 具有单分子传感器阵列的高通量核酸定序

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6270961B1 (en) * 1987-04-01 2001-08-07 Hyseq, Inc. Methods and apparatus for DNA sequencing and DNA identification

Also Published As

Publication number Publication date
DE69929365D1 (de) 2006-03-30
EP1121472A2 (de) 2001-08-08
DE69929365T2 (de) 2006-09-21
WO2000022171A3 (en) 2000-08-31
AU1204600A (en) 2000-05-01
EP1121472B1 (de) 2006-01-04
WO2000022171A2 (en) 2000-04-20

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