ATE310825T1 - Phosphatidyl-3,4,5-triphosphat abhängige proteinkinase - Google Patents

Phosphatidyl-3,4,5-triphosphat abhängige proteinkinase

Info

Publication number
ATE310825T1
ATE310825T1 AT98909642T AT98909642T ATE310825T1 AT E310825 T1 ATE310825 T1 AT E310825T1 AT 98909642 T AT98909642 T AT 98909642T AT 98909642 T AT98909642 T AT 98909642T AT E310825 T1 ATE310825 T1 AT E310825T1
Authority
AT
Austria
Prior art keywords
protein kinase
dependent protein
phosphatidyl
triphosphate
triphosphate dependent
Prior art date
Application number
AT98909642T
Other languages
English (en)
Inventor
Dario Renato Alessi
Original Assignee
Medical Res Council
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9705462.1A external-priority patent/GB9705462D0/en
Priority claimed from GBGB9712826.8A external-priority patent/GB9712826D0/en
Priority claimed from GBGB9717253.0A external-priority patent/GB9717253D0/en
Priority claimed from US08/943,667 external-priority patent/US6734001B1/en
Application filed by Medical Res Council filed Critical Medical Res Council
Application granted granted Critical
Publication of ATE310825T1 publication Critical patent/ATE310825T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
AT98909642T 1997-03-17 1998-03-16 Phosphatidyl-3,4,5-triphosphat abhängige proteinkinase ATE310825T1 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GBGB9705462.1A GB9705462D0 (en) 1997-03-17 1997-03-17 Enzyme
GBGB9712826.8A GB9712826D0 (en) 1997-06-19 1997-06-19 Enyzme
GBGB9717253.0A GB9717253D0 (en) 1997-08-15 1997-08-15 Enzyme
US08/943,667 US6734001B1 (en) 1997-03-17 1997-10-03 3-phosphoinositide-dependent protein kinase
PCT/GB1998/000777 WO1998041638A1 (en) 1997-03-17 1998-03-16 Phosphatidyl-3,4.5-triphosphate-dependent protein kinase

Publications (1)

Publication Number Publication Date
ATE310825T1 true ATE310825T1 (de) 2005-12-15

Family

ID=27451614

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98909642T ATE310825T1 (de) 1997-03-17 1998-03-16 Phosphatidyl-3,4,5-triphosphat abhängige proteinkinase

Country Status (10)

Country Link
US (3) US7205390B2 (de)
EP (1) EP0983363B1 (de)
JP (2) JP3795535B2 (de)
AT (1) ATE310825T1 (de)
AU (1) AU734754B2 (de)
CA (1) CA2284119C (de)
DE (1) DE69832484T2 (de)
DK (1) DK0983363T3 (de)
ES (1) ES2256931T3 (de)
WO (1) WO1998041638A1 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2256931T3 (es) 1997-03-17 2006-07-16 Medical Research Council Proteina quinasa dependiente de fosfatidil-3,4,5-trifosfato.
EP1017826A2 (de) * 1997-09-26 2000-07-12 Onyx Pharmaceuticals Zusammensetzungen und methoden zur identifikation von inhibitoren der pkb-kinase
US6682920B1 (en) * 1997-09-26 2004-01-27 Onyx Pharmaceuticals, Inc. Compositions and methods for identifying PKB kinase inhibitors
AU3591799A (en) * 1998-04-27 1999-11-16 University Health Network Gene screening methods and related assays
CA2355362A1 (en) * 1998-12-14 2000-06-22 Medical Research Council Screening methods based on the use of protein kinases
GB9906245D0 (en) * 1999-03-19 1999-05-12 Medical Res Council Enzyme
EP1234188A2 (de) * 1999-12-02 2002-08-28 The University of Dundee Protein kinase regulierung
GB0213186D0 (en) * 2002-06-08 2002-07-17 Univ Dundee Methods
WO2006127607A2 (en) * 2005-05-23 2006-11-30 The Johns Hopkins University Pi3k pathway mutations in cancer
GB2444853B (en) * 2006-12-14 2010-02-24 Medical Res Council Methods & uses
EP2182058A1 (de) 2008-10-17 2010-05-05 Universität des Saarlandes Hochauflösende Struktur der Proteinkinase-PDK1 und allosterische Effekte niedermolekularer Aktivatoren

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0786004T3 (da) * 1994-10-13 2001-10-22 Max Planck Gesellschaft Kloning, ekspression og karakterisering af en hidtil ukendt form af phosphatidylinositol-3-kinase
US6734001B1 (en) 1997-03-17 2004-05-11 Medical Research Council 3-phosphoinositide-dependent protein kinase
ES2256931T3 (es) 1997-03-17 2006-07-16 Medical Research Council Proteina quinasa dependiente de fosfatidil-3,4,5-trifosfato.
EP1017826A2 (de) 1997-09-26 2000-07-12 Onyx Pharmaceuticals Zusammensetzungen und methoden zur identifikation von inhibitoren der pkb-kinase
US6682920B1 (en) * 1997-09-26 2004-01-27 Onyx Pharmaceuticals, Inc. Compositions and methods for identifying PKB kinase inhibitors

Also Published As

Publication number Publication date
EP0983363B1 (de) 2005-11-23
US20030108971A1 (en) 2003-06-12
AU734754B2 (en) 2001-06-21
DE69832484D1 (en) 2005-12-29
AU6412498A (en) 1998-10-12
ES2256931T3 (es) 2006-07-16
EP0983363A1 (de) 2000-03-08
CA2284119C (en) 2010-06-15
US20050032185A1 (en) 2005-02-10
WO1998041638A1 (en) 1998-09-24
JP2001516218A (ja) 2001-09-25
US7205390B2 (en) 2007-04-17
US20100093027A1 (en) 2010-04-15
US7344870B2 (en) 2008-03-18
CA2284119A1 (en) 1998-09-24
JP2005323611A (ja) 2005-11-24
JP3795535B2 (ja) 2006-07-12
US7842488B2 (en) 2010-11-30
DE69832484T2 (de) 2006-08-10
DK0983363T3 (da) 2006-03-06

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Legal Events

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