ATE309384T1 - Replikationsunfähige herpesvirus-vektoren - Google Patents

Replikationsunfähige herpesvirus-vektoren

Info

Publication number
ATE309384T1
ATE309384T1 AT00985689T AT00985689T ATE309384T1 AT E309384 T1 ATE309384 T1 AT E309384T1 AT 00985689 T AT00985689 T AT 00985689T AT 00985689 T AT00985689 T AT 00985689T AT E309384 T1 ATE309384 T1 AT E309384T1
Authority
AT
Austria
Prior art keywords
inable
replication
nervous system
herpesvirus vectors
peripheral nervous
Prior art date
Application number
AT00985689T
Other languages
English (en)
Inventor
Robert Stuart Coffin
Original Assignee
Biovex Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biovex Ltd filed Critical Biovex Ltd
Application granted granted Critical
Publication of ATE309384T1 publication Critical patent/ATE309384T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/16011—Herpesviridae
    • C12N2710/16611—Simplexvirus, e.g. human herpesvirus 1, 2
    • C12N2710/16641—Use of virus, viral particle or viral elements as a vector
    • C12N2710/16643—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Neurology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Plant Pathology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Virology (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Psychology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
AT00985689T 1999-12-22 2000-12-22 Replikationsunfähige herpesvirus-vektoren ATE309384T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9930419.8A GB9930419D0 (en) 1999-12-22 1999-12-22 Replication incompetent herpes virus vectors
PCT/GB2000/004983 WO2001046450A1 (en) 1999-12-22 2000-12-22 Replication incompetent herpes virus vectors

Publications (1)

Publication Number Publication Date
ATE309384T1 true ATE309384T1 (de) 2005-11-15

Family

ID=10866884

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00985689T ATE309384T1 (de) 1999-12-22 2000-12-22 Replikationsunfähige herpesvirus-vektoren

Country Status (9)

Country Link
US (1) US20030040500A1 (de)
EP (1) EP1246930B1 (de)
JP (1) JP2003518081A (de)
AT (1) ATE309384T1 (de)
AU (1) AU783691B2 (de)
CA (1) CA2395578A1 (de)
DE (1) DE60023944T2 (de)
GB (1) GB9930419D0 (de)
WO (1) WO2001046450A1 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2398335C (en) 2000-01-21 2010-12-07 Biovex Limited Herpes virus strains
US20050267061A1 (en) * 2004-04-08 2005-12-01 Sangamo Biosciences, Inc. Methods and compositions for treating neuropathic and neurodegenerative conditions
GB0317511D0 (en) * 2003-07-25 2003-08-27 Biovex Ltd Viral vectors
EP3938524A1 (de) * 2019-03-14 2022-01-19 Massachusetts Institute of Technology Manipulierte herpes-simplex-virus-1 (hsv-1)-vektoren und ihre verwendungen

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5849571A (en) * 1990-10-10 1998-12-15 University Of Pittsburgh Of The Commonwealth System Of Higher Education Latency active herpes virus promoters and their use
US5763217A (en) * 1993-11-10 1998-06-09 University Of British Columbia Method of using, process of preparing and composition comprising recombinant herpesvirus vectors
GB9524973D0 (en) * 1995-12-06 1996-02-07 Lynxvale Ltd Viral vectors
GB9615794D0 (en) * 1996-07-26 1996-09-04 Medical Res Council Mutant herpes simplex virus strains and uses thereof
GB9801930D0 (en) * 1998-01-29 1998-03-25 Univ London Mutant herpes simplex viruses and uses thereof
GB9930418D0 (en) * 1999-12-22 2000-02-16 Neurovex Ltd Replication incompetent herpes virus vectors

Also Published As

Publication number Publication date
US20030040500A1 (en) 2003-02-27
GB9930419D0 (en) 2000-02-16
AU2208801A (en) 2001-07-03
JP2003518081A (ja) 2003-06-03
AU783691B2 (en) 2005-11-24
DE60023944T2 (de) 2006-07-27
EP1246930A1 (de) 2002-10-09
WO2001046450A1 (en) 2001-06-28
DE60023944D1 (de) 2005-12-15
EP1246930B1 (de) 2005-11-09
CA2395578A1 (en) 2001-06-28

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Legal Events

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