ATE308994T1 - Gebrauch von antikörpern zur verhinderung von auswirkungen hervorgerufen durch grampositive- und myko-bakterien - Google Patents

Gebrauch von antikörpern zur verhinderung von auswirkungen hervorgerufen durch grampositive- und myko-bakterien

Info

Publication number
ATE308994T1
ATE308994T1 AT95933826T AT95933826T ATE308994T1 AT E308994 T1 ATE308994 T1 AT E308994T1 AT 95933826 T AT95933826 T AT 95933826T AT 95933826 T AT95933826 T AT 95933826T AT E308994 T1 ATE308994 T1 AT E308994T1
Authority
AT
Austria
Prior art keywords
mycobacteria
grampositive
antibodies
effects caused
prevent effects
Prior art date
Application number
AT95933826T
Other languages
English (en)
Inventor
Richard J Ulevitch
Peter S Tobias
Jerome Pugin
Original Assignee
Scripps Research Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scripps Research Inst filed Critical Scripps Research Inst
Application granted granted Critical
Publication of ATE308994T1 publication Critical patent/ATE308994T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/241—Tumor Necrosis Factors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2896—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/77—Internalization into the cell

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Pulmonology (AREA)
  • Hematology (AREA)
  • Communicable Diseases (AREA)
  • Diabetes (AREA)
  • Oncology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Urology & Nephrology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
AT95933826T 1994-09-16 1995-09-15 Gebrauch von antikörpern zur verhinderung von auswirkungen hervorgerufen durch grampositive- und myko-bakterien ATE308994T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US30793194A 1994-09-16 1994-09-16
PCT/US1995/011770 WO1996008272A1 (en) 1994-09-16 1995-09-15 Use of antibodies to block the effects of gram-positive bacteria and mycobacteria

Publications (1)

Publication Number Publication Date
ATE308994T1 true ATE308994T1 (de) 2005-11-15

Family

ID=23191790

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95933826T ATE308994T1 (de) 1994-09-16 1995-09-15 Gebrauch von antikörpern zur verhinderung von auswirkungen hervorgerufen durch grampositive- und myko-bakterien

Country Status (9)

Country Link
US (3) US6168790B1 (de)
EP (1) EP0792162B1 (de)
JP (1) JP3892902B2 (de)
AT (1) ATE308994T1 (de)
CA (1) CA2200054C (de)
DE (1) DE69534601T2 (de)
DK (1) DK0792162T3 (de)
ES (1) ES2255708T3 (de)
WO (1) WO1996008272A1 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5766593A (en) * 1994-12-30 1998-06-16 Amgen Inc. Anti-inflammatory CD14 peptides
WO1997000081A1 (en) * 1995-06-19 1997-01-03 Goyert Sanna M A method for inhibiting bacteremia and bacterial dissemination
US6610293B1 (en) * 1997-06-16 2003-08-26 The Henry M. Jackson Foundation For The Advancement Of Military Medicine Opsonic and protective monoclonal and chimeric antibodies specific for lipoteichoic acid of gram positive bacteria
WO2000042994A2 (en) * 1999-01-21 2000-07-27 North Shore-Long Island Jewish Research Institute Inhibition of bacterial dissemination
EP1213586A4 (de) * 1999-09-17 2003-02-05 Mochida Pharm Co Ltd Verfahren zum fraktionierten messen von löslichem cd14-protein
AU2001244711A1 (en) * 2000-03-31 2001-10-08 Mochida Pharmaceutical Co., Ltd. Tlr/cd14 binding inhibitor
US7264967B2 (en) 2000-11-22 2007-09-04 Mochida Pharmaceutical Co., Ltd. Anti-CD14 monoclonal antibody having effect of inhibiting CD14/TLR binding
US20040028651A1 (en) * 2001-03-29 2004-02-12 Karrupiah Muthumani Composition and methods of using hiv vpr
WO2003030827A2 (en) * 2001-10-05 2003-04-17 The Trustees Of The University Of Pennsylvania Compositions for and methods of treating and preventing sirs/sepsis
US8329169B2 (en) * 2003-05-15 2012-12-11 Genentech, Inc. Methods and compositions for the prevention and treatment of sepsis
SG192047A1 (en) 2011-01-24 2013-08-30 Univ Singapore Pathogenic mycobacteria-derived mannose-capped lipoarabinomannan antigen binding proteins
EP3612566A4 (de) 2017-04-21 2021-03-03 Implicit Bioscience Limited Cd14-antagonist-antikörper zur behandlung von neurodegenerativen erkrankungen

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI920450A7 (fi) * 1989-08-01 1992-01-31 Scripps Clinic And Res Foundation Menetelmiä ja koostumuksia verenmyrkytyksen oireiden estämiseksi
JPH06504033A (ja) * 1990-02-01 1994-05-12 ザ ロックフェラー ユニバーシティ リポ多糖結合オプソニン及びその使用法
ATE335072T1 (de) * 1993-05-28 2006-08-15 Scripps Research Inst Methoden für inhibition der cd14-abhängigen zellaktivierung

Also Published As

Publication number Publication date
ES2255708T3 (es) 2006-07-01
CA2200054C (en) 2010-03-16
US6168790B1 (en) 2001-01-02
DE69534601T2 (de) 2006-08-03
EP0792162B1 (de) 2005-11-09
WO1996008272A1 (en) 1996-03-21
AU703169B2 (en) 1999-03-18
JP3892902B2 (ja) 2007-03-14
DE69534601D1 (de) 2005-12-15
EP0792162A4 (de) 2003-03-19
JPH10505839A (ja) 1998-06-09
CA2200054A1 (en) 1996-03-21
AU3633695A (en) 1996-03-29
US20030103969A1 (en) 2003-06-05
US20010022969A1 (en) 2001-09-20
EP0792162A1 (de) 1997-09-03
DK0792162T3 (da) 2006-03-27

Similar Documents

Publication Publication Date Title
FI920450A0 (fi) Metoder och kompositioner foer foerhindrande av symtomer av sepsis.
DE69534601D1 (de) Gebrauch von antikörpern zur verhinderung von auswirkungen hervorgerufen durch grampositive- und myko-bakterien
ATE448792T1 (de) Verwendung von botulinumtoxin zur behandlung der renitenten blasenentleerungsstörung
DE69129989D1 (de) Arzneimittelzusammensetzung zur behandlung oder vorbeugung maligner tumore
ATE172880T1 (de) Verwendung von monoklonalen anti-tnf-antikörpern für die behandlung von bakteriellen meningitiden
EP0751781A4 (de) Methode zur prävention oder behandlung einer krankheit, dadurch charakterisiert, dass die neoplastischen zellen cd40 exprimieren
ATE248605T1 (de) Für e-selectin und p-selectin spezifische kreuzreaktive monoklonale antikörper
RU2000105905A (ru) Способ лечения острого повреждения легких и способ лечения фиброза, моноклональное антитело, гибридома атсс нв12382
SE8605295D0 (sv) Monoclonal antibodies cross-reactive and crossprotective against p. aeruginosa serotypes
DE59508864D1 (de) MONOKLONALER ANTIKÖRPER GEGEN CD44v6
ATA29495A (de) Zusammensetzung und verfahren zur prävention und behandlung von entzündungen mit immunglobulin a
ATE410514T1 (de) Calciumbindende rekombinante antikörper gegen protein c
EP0736033A4 (de) Neue therapeutische kohlenhydratmischungen zur verwendung bei prämenstruellem syndrom
BG99074A (bg) Рекомбинантни човешки нiv-неутрализиращи моноклонални антитела за профилактика и лечение на нiv инфекция
DK1042492T3 (da) Humaniserede monoklonale antistoffer der beskytter med Shiga-toksininducerede sygdomme
DE69327248D1 (de) Verfahren zur behandlung des symptomenkomplexes des prämenstruellen syndroms mit vitamin d oder vitamin d und calcium
ATE136222T1 (de) Heilmittel und verfahren zur inhibierung der vaskularisierung von tumoren
DE69434220D1 (de) Verfahren zur verhütung der nebenwirkungen und unempfindlichkeit gegenüber therapeutischen verwendungen von toxinen
FR2672888B1 (fr) Nouvelles urees et thiourees, leur preparation et leur application en therapeutique.
Moroz et al. Neutralization of Vipera palestinae hemorrhagin by antibody fragments
DE69127346D1 (de) Behandlung thrombotischer ereignisse
FI924278A0 (fi) Bcrf1 antagonister foer skoetsel av epstein-barr-virusinfektioner.
NZ329403A (en) Treatment of B-cell lymphomas using a CD40 binding protein that inhibits the binding of CD40 to CD40L

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties