ATE303144T1 - Hemmung der fettsäuresynthase als mittel zur verminderung der adipozytenmenge - Google Patents

Hemmung der fettsäuresynthase als mittel zur verminderung der adipozytenmenge

Info

Publication number
ATE303144T1
ATE303144T1 AT96939542T AT96939542T ATE303144T1 AT E303144 T1 ATE303144 T1 AT E303144T1 AT 96939542 T AT96939542 T AT 96939542T AT 96939542 T AT96939542 T AT 96939542T AT E303144 T1 ATE303144 T1 AT E303144T1
Authority
AT
Austria
Prior art keywords
reduce
weight loss
complications
reduction
fatty acid
Prior art date
Application number
AT96939542T
Other languages
English (en)
Inventor
Francis P Kuhajda
Gary R Pasternack
Craig A Townsend
Neelakandha S Mani
Original Assignee
Univ Johns Hopkins
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Johns Hopkins filed Critical Univ Johns Hopkins
Application granted granted Critical
Publication of ATE303144T1 publication Critical patent/ATE303144T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Child & Adolescent Psychology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Obesity (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
AT96939542T 1995-11-17 1996-11-15 Hemmung der fettsäuresynthase als mittel zur verminderung der adipozytenmenge ATE303144T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US694095P 1995-11-17 1995-11-17
PCT/US1996/017678 WO1997018806A1 (en) 1995-11-17 1996-11-15 Inhibition of fatty acid synthase as a means to reduce adipocyte mass

Publications (1)

Publication Number Publication Date
ATE303144T1 true ATE303144T1 (de) 2005-09-15

Family

ID=21723376

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96939542T ATE303144T1 (de) 1995-11-17 1996-11-15 Hemmung der fettsäuresynthase als mittel zur verminderung der adipozytenmenge

Country Status (7)

Country Link
EP (1) EP0869784B1 (de)
AT (1) ATE303144T1 (de)
AU (1) AU7668596A (de)
DE (1) DE69635130T2 (de)
DK (1) DK0869784T3 (de)
ES (1) ES2251002T3 (de)
WO (1) WO1997018806A1 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6001968A (en) * 1994-08-17 1999-12-14 The Rockefeller University OB polypeptides, modified forms and compositions
IL159296A0 (en) 2001-06-13 2004-06-01 Magnachem Int Lab Inc Lactone formulations and method of use
US8188145B2 (en) 2002-06-12 2012-05-29 Magnachem International Laboratories, Inc. Synthetic lactone formulations and method of use
CN101633650A (zh) * 2002-07-01 2010-01-27 法斯根有限责任公司 新化合物、包含该化合物的药物组合物及该化合物的应用方法
CA2687964A1 (en) 2007-06-01 2009-02-19 The Trustees Of Princeton University Treatment of viral infections by modulation of host cell metabolic pathways
MX2011004331A (es) 2008-10-24 2011-09-21 Magnachem Int Lab Inc Metodo para busqueda de compuestos que interactuan selectivamente con rad9.
US8729239B2 (en) 2009-04-09 2014-05-20 Nuclea Biotechnologies, Inc. Antibodies against fatty acid synthase
PT2968316T (pt) 2013-03-13 2019-10-29 Forma Therapeutics Inc Derivados de 2-hidroxi-1-{4-[(4-fenilfenil)carbonil]piperazin-1-il}etano-1-ona e compostos relacionados como inibidores da sintase de ácidos gordos (fasn) para o tratamento do cancro

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4028397A (en) * 1973-07-05 1977-06-07 Hoffmann-La Roche Inc. Hydroxycitric acid derivatives
US4218443A (en) * 1979-01-15 1980-08-19 Hoffmann-La Roche Inc. Polyether ionophores as antiobesity and hypotriglyceridemic agents
US5246960A (en) * 1984-12-21 1993-09-21 Hoffmann-La Roche Inc. Oxetanones
JP2746372B2 (ja) * 1988-03-11 1998-05-06 科研製薬株式会社 Ｆ−０３６８物質
GB9209628D0 (en) * 1992-05-05 1992-06-17 Smithkline Beecham Plc Compounds
KR100325766B1 (ko) * 1992-07-24 2002-07-27 더 존스 홉킨스 유니버시티 암치료를위한지방산합성억제제를함유하는약학조성물

Also Published As

Publication number Publication date
ES2251002T3 (es) 2006-04-16
EP0869784A4 (de) 2001-02-07
EP0869784B1 (de) 2005-08-31
DK0869784T3 (da) 2006-01-16
DE69635130D1 (de) 2005-10-06
AU7668596A (en) 1997-06-11
WO1997018806A1 (en) 1997-05-29
DE69635130T2 (de) 2006-06-14
EP0869784A1 (de) 1998-10-14

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