DK0869784T3 - Hæmning af fedtsyresyntase som middel til formindskelse af adipocytmængden - Google Patents

Hæmning af fedtsyresyntase som middel til formindskelse af adipocytmængden

Info

Publication number
DK0869784T3
DK0869784T3 DK96939542T DK96939542T DK0869784T3 DK 0869784 T3 DK0869784 T3 DK 0869784T3 DK 96939542 T DK96939542 T DK 96939542T DK 96939542 T DK96939542 T DK 96939542T DK 0869784 T3 DK0869784 T3 DK 0869784T3
Authority
DK
Denmark
Prior art keywords
reduce
weight loss
complications
adipocyte
reduction
Prior art date
Application number
DK96939542T
Other languages
Danish (da)
English (en)
Inventor
Francis P Kuhajda
Gary R Pasternack
Craig A Townsend
Neelakandha Mani
Original Assignee
Univ Johns Hopkins
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Johns Hopkins filed Critical Univ Johns Hopkins
Application granted granted Critical
Publication of DK0869784T3 publication Critical patent/DK0869784T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Child & Adolescent Psychology (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK96939542T 1995-11-17 1996-11-15 Hæmning af fedtsyresyntase som middel til formindskelse af adipocytmængden DK0869784T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US694095P 1995-11-17 1995-11-17

Publications (1)

Publication Number Publication Date
DK0869784T3 true DK0869784T3 (da) 2006-01-16

Family

ID=21723376

Family Applications (1)

Application Number Title Priority Date Filing Date
DK96939542T DK0869784T3 (da) 1995-11-17 1996-11-15 Hæmning af fedtsyresyntase som middel til formindskelse af adipocytmængden

Country Status (7)

Country Link
EP (1) EP0869784B1 (de)
AT (1) ATE303144T1 (de)
AU (1) AU7668596A (de)
DE (1) DE69635130T2 (de)
DK (1) DK0869784T3 (de)
ES (1) ES2251002T3 (de)
WO (1) WO1997018806A1 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6001968A (en) 1994-08-17 1999-12-14 The Rockefeller University OB polypeptides, modified forms and compositions
CA2450660C (en) 2001-06-13 2011-08-16 Magnachem International Laboratories, Inc. Lactone formulations and method of use
US8188145B2 (en) 2002-06-12 2012-05-29 Magnachem International Laboratories, Inc. Synthetic lactone formulations and method of use
IL166054A0 (en) * 2002-07-01 2006-01-15 Univ Johns Hopkins Novel compounds pharmaceutical compositions containing same and methods of use for same
WO2009023059A2 (en) 2007-06-01 2009-02-19 The Trustees Of Princeton University Treatment of viral infections by modulation of host cell metabolic pathways
WO2010048616A2 (en) 2008-10-24 2010-04-29 Magnachem International Laboratories, Inc. Method for screening for compounds selectively interacting with rad9
WO2010118324A2 (en) 2009-04-09 2010-10-14 Nuclea Biotechnologies, LLC Antibodies against fatty acid synthase
CN112521369A (zh) 2013-03-13 2021-03-19 福马治疗股份有限公司 用于抑制fasn的化合物及组合物

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4028397A (en) * 1973-07-05 1977-06-07 Hoffmann-La Roche Inc. Hydroxycitric acid derivatives
US4218443A (en) * 1979-01-15 1980-08-19 Hoffmann-La Roche Inc. Polyether ionophores as antiobesity and hypotriglyceridemic agents
US5246960A (en) * 1984-12-21 1993-09-21 Hoffmann-La Roche Inc. Oxetanones
JP2746372B2 (ja) * 1988-03-11 1998-05-06 科研製薬株式会社 Ｆ−０３６８物質
US5447954A (en) * 1992-05-05 1995-09-05 Smithkline Beecham P.L.C. Phenylderivate as inhibitors of ATP citrate lyase
DE69332353T2 (de) * 1992-07-24 2003-07-10 The Johns Hopkins University, Baltimore Verwendung von inhibitoren der synthese von fettsäuren zur behandlung von krebs

Also Published As

Publication number Publication date
ATE303144T1 (de) 2005-09-15
DE69635130D1 (de) 2005-10-06
ES2251002T3 (es) 2006-04-16
AU7668596A (en) 1997-06-11
EP0869784A1 (de) 1998-10-14
EP0869784A4 (de) 2001-02-07
WO1997018806A1 (en) 1997-05-29
DE69635130T2 (de) 2006-06-14
EP0869784B1 (de) 2005-08-31

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