ATE301660T1 - Analoge von 4-beta-1''-((2''-(substitutierte- benzoyl)anilin)-podophyllotoxin zur verwendung als antikrebs-agentia - Google Patents
Analoge von 4-beta-1''-((2''-(substitutierte- benzoyl)anilin)-podophyllotoxin zur verwendung als antikrebs-agentiaInfo
- Publication number
- ATE301660T1 ATE301660T1 AT02718512T AT02718512T ATE301660T1 AT E301660 T1 ATE301660 T1 AT E301660T1 AT 02718512 T AT02718512 T AT 02718512T AT 02718512 T AT02718512 T AT 02718512T AT E301660 T1 ATE301660 T1 AT E301660T1
- Authority
- AT
- Austria
- Prior art keywords
- podophyllotoxin
- benzoyl
- substituted
- aniline
- analogue
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/IN2002/000091 WO2003082876A1 (en) | 2002-03-28 | 2002-03-28 | 4-beta-1''-`(2''-(substituted benzoyl)anilino! podophyllotoxin analogues useful as anticancer agents |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE301660T1 true ATE301660T1 (de) | 2005-08-15 |
Family
ID=28460465
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT02718512T ATE301660T1 (de) | 2002-03-28 | 2002-03-28 | Analoge von 4-beta-1''-((2''-(substitutierte- benzoyl)anilin)-podophyllotoxin zur verwendung als antikrebs-agentia |
Country Status (8)
Country | Link |
---|---|
US (1) | US7087641B2 (de) |
EP (1) | EP1377588B1 (de) |
JP (1) | JP2005521729A (de) |
AT (1) | ATE301660T1 (de) |
AU (1) | AU2002249559A1 (de) |
DE (1) | DE60205470T2 (de) |
ES (1) | ES2247315T3 (de) |
WO (1) | WO2003082876A1 (de) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2004073375A2 (en) * | 2003-02-18 | 2004-09-02 | Ranbaxy Laboratories Limited | Podophyllotoxin derivatives as antitumor agents |
FR2869035B1 (fr) * | 2004-04-16 | 2006-07-14 | Pierre Fabre Medicament Sa | Derives (poly)aminoalkylaminoacetamide d'epipodophyllotoxine leur procede de preparation et leurs applications en therapeutique comme agent anticancereux |
FR2935143B1 (fr) | 2008-08-19 | 2010-12-03 | Pf Medicament | Nouveaus derives (poly)aminoalkylaminoalkylamides, alkyl-urees, ou alkyl-sulfonamides d'epipodophyllotoxine, leur procede de preparation et leur application en therapeuthique comme agent cancereux |
WO2010052733A1 (en) * | 2008-11-07 | 2010-05-14 | Council Of Scientific & Industrial Research | NOVEL 4β-AMINO PODOPHVLLOTOXIN CONGENERS AS ANTI TUMOUR ANTIBIOTICS A PROCESS FOR THE PREPARATION THEREOF |
WO2012000118A1 (en) | 2010-07-02 | 2012-01-05 | Angiochem Inc. | Short and d-amino acid-containing polypeptides for therapeutic conjugates and uses thereof |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5300500A (en) * | 1989-02-23 | 1994-04-05 | The University Of North Carolina At Chapel Hill | 4 beta-amino podophyllotoxin analog compounds and methods |
US5332811A (en) | 1989-09-12 | 1994-07-26 | The University Of North Carolina At Chapel Hill | Etopside analogs |
US6713454B1 (en) * | 1999-09-13 | 2004-03-30 | Nobex Corporation | Prodrugs of etoposide and etoposide analogs |
FR2810321B1 (fr) * | 2000-06-20 | 2002-07-26 | Adir | Nouveaux derives de podophyllotoxine carbamate et thiocarbamate, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
US6566393B1 (en) * | 2002-06-21 | 2003-05-20 | The University Of North Carolina At Chapel Hill | Etoposide analogs and methods of use thereof |
-
2002
- 2002-03-28 AT AT02718512T patent/ATE301660T1/de not_active IP Right Cessation
- 2002-03-28 DE DE60205470T patent/DE60205470T2/de not_active Expired - Lifetime
- 2002-03-28 EP EP02718512A patent/EP1377588B1/de not_active Expired - Lifetime
- 2002-03-28 AU AU2002249559A patent/AU2002249559A1/en not_active Abandoned
- 2002-03-28 US US10/381,027 patent/US7087641B2/en not_active Expired - Fee Related
- 2002-03-28 WO PCT/IN2002/000091 patent/WO2003082876A1/en active IP Right Grant
- 2002-03-28 JP JP2003580341A patent/JP2005521729A/ja active Pending
- 2002-03-28 ES ES02718512T patent/ES2247315T3/es not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
US7087641B2 (en) | 2006-08-08 |
WO2003082876A1 (en) | 2003-10-09 |
US20050101804A1 (en) | 2005-05-12 |
AU2002249559A1 (en) | 2003-10-13 |
EP1377588A1 (de) | 2004-01-07 |
DE60205470T2 (de) | 2006-05-24 |
ES2247315T3 (es) | 2006-03-01 |
JP2005521729A (ja) | 2005-07-21 |
DE60205470D1 (de) | 2005-09-15 |
EP1377588B1 (de) | 2005-08-10 |
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