ATE300539T1 - Oxo-pyridoimidazol-carboxamide: gaba-rezeptor- liganden im gehirn - Google Patents

Oxo-pyridoimidazol-carboxamide: gaba-rezeptor- liganden im gehirn

Info

Publication number
ATE300539T1
ATE300539T1 AT99943913T AT99943913T ATE300539T1 AT E300539 T1 ATE300539 T1 AT E300539T1 AT 99943913 T AT99943913 T AT 99943913T AT 99943913 T AT99943913 T AT 99943913T AT E300539 T1 ATE300539 T1 AT E300539T1
Authority
AT
Austria
Prior art keywords
pyridoimidazole
carboxamide
oxo
brain
receptor ligands
Prior art date
Application number
AT99943913T
Other languages
English (en)
Inventor
Bogumila Rachwal
Pamela Albaugh
Kenneth Shaw
Original Assignee
Neurogen Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Neurogen Corp filed Critical Neurogen Corp
Application granted granted Critical
Publication of ATE300539T1 publication Critical patent/ATE300539T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Addiction (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AT99943913T 1998-08-25 1999-08-25 Oxo-pyridoimidazol-carboxamide: gaba-rezeptor- liganden im gehirn ATE300539T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US9784198P 1998-08-25 1998-08-25
US15936298A 1998-09-23 1998-09-23
PCT/US1999/019400 WO2000010973A2 (en) 1998-08-25 1999-08-25 Oxo-pyridoimidazole-carboxamides: gaba brain receptor ligands

Publications (1)

Publication Number Publication Date
ATE300539T1 true ATE300539T1 (de) 2005-08-15

Family

ID=26793697

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99943913T ATE300539T1 (de) 1998-08-25 1999-08-25 Oxo-pyridoimidazol-carboxamide: gaba-rezeptor- liganden im gehirn

Country Status (8)

Country Link
EP (1) EP1107966B1 (de)
JP (1) JP2002523399A (de)
AT (1) ATE300539T1 (de)
AU (1) AU5691199A (de)
CA (1) CA2341531A1 (de)
DE (1) DE69926378T2 (de)
ES (1) ES2246090T3 (de)
WO (1) WO2000010973A2 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2391766A1 (en) 1999-08-02 2001-02-08 Ortho-Mcneil Pharmaceutical, Inc. C-6 ring-substituted pyrido[1,2-a]benzimidazole derivatives usefu l in treating central nervous system disorders

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994004532A1 (en) * 1992-08-19 1994-03-03 Mcneilab, Inc. 3-oxo-pyrido(1,2-a^_)benzimidazole-4-carboxyl and 4-oxo-azepino(1,2-a^_)benzimidazole-5-carboxyl derivatives useful in treating central nervous system disorders
JP2001501949A (ja) * 1996-10-07 2001-02-13 オーソ―マクニール・フアーマシユーチカル・インコーポレーテツド 中枢神経系疾患を処置することに有用な５―ヘテロ原子を含有するアルキル置換された―３―オキソ―ピリド（１，２―ａ）ベンゾイミダゾール―４―カルボキサミド誘導体

Also Published As

Publication number Publication date
WO2000010973A2 (en) 2000-03-02
ES2246090T3 (es) 2006-02-01
EP1107966A2 (de) 2001-06-20
CA2341531A1 (en) 2000-03-02
DE69926378D1 (de) 2005-09-01
JP2002523399A (ja) 2002-07-30
AU5691199A (en) 2000-03-14
WO2000010973A3 (en) 2000-06-29
EP1107966B1 (de) 2005-07-27
DE69926378T2 (de) 2005-12-29

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Legal Events

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