ATE295156T1 - Mehrlagige polyelektrolytkapseln mit gesteuerter und verzögerter freisetzung - Google Patents
Mehrlagige polyelektrolytkapseln mit gesteuerter und verzögerter freisetzungInfo
- Publication number
- ATE295156T1 ATE295156T1 AT01980290T AT01980290T ATE295156T1 AT E295156 T1 ATE295156 T1 AT E295156T1 AT 01980290 T AT01980290 T AT 01980290T AT 01980290 T AT01980290 T AT 01980290T AT E295156 T1 ATE295156 T1 AT E295156T1
- Authority
- AT
- Austria
- Prior art keywords
- polyelectrolyte
- release
- fluorescein
- shell
- layer
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
- B01J13/02—Making microcapsules or microballoons
- B01J13/20—After-treatment of capsule walls, e.g. hardening
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Dispersion Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Preparation (AREA)
- Manufacturing Of Micro-Capsules (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP00118615 | 2000-08-28 | ||
EP01112600 | 2001-05-23 | ||
PCT/EP2001/009908 WO2002017888A2 (en) | 2000-08-28 | 2001-08-28 | Controlled and sustained release properties of polyelectrolyte multilayer capsules |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE295156T1 true ATE295156T1 (de) | 2005-05-15 |
Family
ID=26071336
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT01980290T ATE295156T1 (de) | 2000-08-28 | 2001-08-28 | Mehrlagige polyelektrolytkapseln mit gesteuerter und verzögerter freisetzung |
Country Status (7)
Country | Link |
---|---|
US (1) | US20040013721A1 (de) |
EP (1) | EP1313455B1 (de) |
JP (1) | JP2004507488A (de) |
AT (1) | ATE295156T1 (de) |
CA (1) | CA2420523C (de) |
DE (1) | DE60110809T2 (de) |
WO (1) | WO2002017888A2 (de) |
Families Citing this family (65)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20080026068A1 (en) * | 2001-08-16 | 2008-01-31 | Baxter Healthcare S.A. | Pulmonary delivery of spherical insulin microparticles |
US7504364B2 (en) * | 2002-03-01 | 2009-03-17 | Receptors Llc | Methods of making arrays and artificial receptors |
CN1656234B (zh) * | 2002-03-20 | 2012-02-01 | 创新生物公司 | 包囊化核酸扩增反应混合物的微胶囊及其作为反应隔间进行平行反应的用途 |
US7101947B2 (en) | 2002-06-14 | 2006-09-05 | Florida State University Research Foundation, Inc. | Polyelectrolyte complex films for analytical and membrane separation of chiral compounds |
US20040137039A1 (en) * | 2002-07-22 | 2004-07-15 | Trustees Of Stevens Institute Of Technology | Methods for controlled release of molecules from layered polymer films |
DE50308422D1 (de) * | 2002-08-02 | 2007-11-29 | Capsulution Nanoscience Ag | Farbkodierte layer-by-layer mikrokapseln als kombinatorische analysebibliotheken und als spezifische optische sensoren |
US20050037381A1 (en) * | 2002-09-16 | 2005-02-17 | Receptors Llc | Artificial receptors, building blocks, and methods |
US20050037429A1 (en) * | 2003-03-28 | 2005-02-17 | Receptors Llc | Artificial receptors including reversibly immobilized building blocks and methods |
US7469076B2 (en) * | 2003-09-03 | 2008-12-23 | Receptors Llc | Sensors employing combinatorial artificial receptors |
WO2005003326A2 (en) | 2003-03-28 | 2005-01-13 | Receptors Llc. | Artificial receptors including reversibly immobilized building blocks and methods |
US20040137481A1 (en) * | 2002-09-16 | 2004-07-15 | Receptors Llc | Artificial receptor building blocks, components, and kits |
US20050136483A1 (en) * | 2003-09-03 | 2005-06-23 | Receptors Llc | Nanodevices employing combinatorial artificial receptors |
US20060057625A1 (en) * | 2002-09-16 | 2006-03-16 | Carlson Robert E | Scaffold-based artificial receptors and methods |
JP4684991B2 (ja) | 2003-01-31 | 2011-05-18 | ボストン サイエンティフィック リミテッド | 薬物添加ナノカプセルを用いる局所的薬物デリバリー |
DE10361084A1 (de) | 2003-06-13 | 2005-01-05 | Henkel Kgaa | Lagerstabile Bleichmittelzusammensetzungen auf Basis von Peroxycarbonsäuren |
US7364585B2 (en) | 2003-08-11 | 2008-04-29 | Boston Scientific Scimed, Inc. | Medical devices comprising drug-loaded capsules for localized drug delivery |
US7348399B2 (en) | 2003-08-29 | 2008-03-25 | Louisiana Tech University Foundation, Inc. | Nanofabricated polypeptide multilayer films, coatings, and microcapsules |
US7615530B2 (en) * | 2003-08-29 | 2009-11-10 | Artificial Cell Technologies, Inc. | Immunogenic compositions and methods of use |
US7544770B2 (en) | 2003-08-29 | 2009-06-09 | Louisiana Tech Foundation, Inc. | Multilayer films, coatings, and microcapsules comprising polypeptides |
US7550557B2 (en) | 2003-08-29 | 2009-06-23 | Louisiana Tech University Foundation, Inc. | Multilayer films, coatings, and microcapsules comprising polypeptides |
CA2559893A1 (en) * | 2004-03-11 | 2005-09-22 | University Of Massachusetts | Biopolymer encapsulation and stabilization of lipid systems and methods for utilization thereof |
EP1593374A1 (de) * | 2004-05-07 | 2005-11-09 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | Ferngesteuerte Freisetzung verkapselter Materialien |
US8728525B2 (en) * | 2004-05-12 | 2014-05-20 | Baxter International Inc. | Protein microspheres retaining pharmacokinetic and pharmacodynamic properties |
US8119153B2 (en) | 2004-08-26 | 2012-02-21 | Boston Scientific Scimed, Inc. | Stents with drug eluting coatings |
WO2006029234A1 (en) | 2004-09-03 | 2006-03-16 | Receptors Llc | Combinatorial artificial receptors including tether building blocks |
EP1789792A2 (de) * | 2004-09-11 | 2007-05-30 | Receptors LLC | Kombinatorische künstliche rezeptoren mit peptidbausteinen |
CA2583054A1 (en) * | 2004-10-05 | 2006-04-13 | The University Of Melbourne | Porous polyelectrolyte materials |
WO2006041541A1 (en) | 2004-10-07 | 2006-04-20 | Christopher White | A mixing system |
WO2006066131A1 (en) * | 2004-12-17 | 2006-06-22 | Cabot Corporation | Inkjet inks comprising multi-layer pigments |
CN101188996B (zh) * | 2005-04-27 | 2013-03-27 | 巴克斯特国际公司 | 表面改性的微粒及其形成和使用方法 |
US20070048383A1 (en) * | 2005-08-25 | 2007-03-01 | Helmus Michael N | Self-assembled endovascular structures |
DE102005044400A1 (de) * | 2005-09-16 | 2007-03-22 | Capsulution Nanoscience Ag | Verfahren zur Verkapselung und kontrollierten Freisetzung von schwer wasserlöslichen (hydrophoben) flüssigen und festen Wirkstoffen |
AU2006347951B2 (en) | 2005-10-25 | 2011-12-22 | Louisiana Tech University Research Foundation | Multilayer films, coatings and microcapsules comprising polypeptides |
JP5189493B2 (ja) * | 2005-11-14 | 2013-04-24 | ルイジアナ テク ユニバーシティ リサーチ ファウンデーション | ポリペプチド膜および方法 |
RU2300369C1 (ru) * | 2005-12-27 | 2007-06-10 | Наталья Ивановна Ларионова | Способ получения полиэлектролитных микрочастиц, содержащих инкапсулируемое вещество, чувствительных к изменению состава окружающей среды |
US8834912B2 (en) * | 2005-12-30 | 2014-09-16 | Boston Scientific Scimed, Inc. | Medical devices having multiple charged layers |
US20070281031A1 (en) * | 2006-06-01 | 2007-12-06 | Guohan Yang | Microparticles and methods for production thereof |
US20100015068A1 (en) * | 2006-07-06 | 2010-01-21 | Massachusetts Institute Of Technology | Methods and Compositions For Altering Biological Surfaces |
AU2007281737B2 (en) | 2006-08-04 | 2013-09-19 | Baxter Healthcare S.A. | Microsphere-based composition for preventing and/or reversing new-onset autoimmune diabetes |
US8337809B2 (en) * | 2006-09-11 | 2012-12-25 | William Marsh Rice University | Charge-assembled capsules for phototherapy |
US20080213334A1 (en) * | 2006-09-29 | 2008-09-04 | Lockwood Nathan A | Polyelectrolyte media for bioactive agent delivery |
AU2007319577A1 (en) * | 2006-10-06 | 2008-05-22 | Baxter Healthcare S.A. | Microencapsules containing surface-modified microparticles and methods of forming and using the same |
US20080248108A1 (en) * | 2006-10-06 | 2008-10-09 | Jain Krotz | Multilayered polyelectrolyte-based capsules for cell encapsulation and delivery of therapeutic compositions |
CA2675972C (en) * | 2007-01-22 | 2015-06-02 | Artificial Cell Technologies, Inc. | Polypeptide films and methods |
US8093039B2 (en) | 2007-04-10 | 2012-01-10 | The Trustees Of The Stevens Institute Of Technology | Surfaces differentially adhesive to eukaryotic cells and non-eukaryotic cells |
DE102007024642A1 (de) | 2007-05-24 | 2008-11-27 | Eyesense Ag | Hydrogel-Implantat für Sensorik von Metaboliten am Auge |
US20080311177A1 (en) | 2007-06-14 | 2008-12-18 | Massachusetts Institute Of Technology | Self Assembled Films for Protein and Drug Delivery Applications |
US9198875B2 (en) * | 2008-08-17 | 2015-12-01 | Massachusetts Institute Of Technology | Controlled delivery of bioactive agents from decomposable films |
US8323615B2 (en) * | 2008-08-20 | 2012-12-04 | Baxter International Inc. | Methods of processing multi-phasic dispersions |
US8323685B2 (en) * | 2008-08-20 | 2012-12-04 | Baxter International Inc. | Methods of processing compositions containing microparticles |
US20100047292A1 (en) * | 2008-08-20 | 2010-02-25 | Baxter International Inc. | Methods of processing microparticles and compositions produced thereby |
US8367427B2 (en) * | 2008-08-20 | 2013-02-05 | Baxter International Inc. | Methods of processing compositions containing microparticles |
GB0918564D0 (en) * | 2009-10-22 | 2009-12-09 | Plasticell Ltd | Nested cell encapsulation |
US9321030B2 (en) | 2012-01-04 | 2016-04-26 | The Trustees Of The Stevens Institute Of Technology | Clay-containing thin films as carriers of absorbed molecules |
WO2013163234A1 (en) * | 2012-04-23 | 2013-10-31 | Massachusetts Institute Of Technology | Stable layer-by-layer coated particles |
WO2014134029A1 (en) | 2013-02-26 | 2014-09-04 | Massachusetts Institute Of Technology | Nucleic acid particles, methods and use thereof |
WO2014150074A1 (en) | 2013-03-15 | 2014-09-25 | Massachusetts Institute Of Technology | Compositions and methods for nucleic acid delivery |
MX2016003090A (es) | 2013-09-27 | 2016-05-31 | Rohm & Haas | Desintegracion activada por fuerza ionica de peliculas y de particulas. |
JP6608831B2 (ja) | 2013-09-27 | 2019-11-20 | ローム アンド ハース カンパニー | 高水分含有配合物を包装するための水分散性膜 |
CN104945764A (zh) * | 2014-03-28 | 2015-09-30 | 苏州工业园区新国大研究院 | 介电材料及使用该介电材料的电容器 |
CN107119111B (zh) * | 2017-03-28 | 2021-02-12 | 浙江大学 | 一种dna酶包裹的dna分子层层自组装微胶囊及其制备与应用 |
WO2019089567A1 (en) | 2017-10-30 | 2019-05-09 | Massachusetts Institute Of Technology | Layer-by-layer nanoparticles for cytokine therapy in cancer treatment |
MX2021003772A (es) | 2018-10-26 | 2021-05-27 | Illumina Inc | Modulacion de globulos de polimero para procesamiento de adn. |
US12018315B2 (en) | 2019-05-30 | 2024-06-25 | Massachusetts Institute Of Technology | Peptide nucleic acid functionalized hydrogel microneedles for sampling and detection of interstitial fluid nucleic acids |
CN111855528B (zh) * | 2020-07-23 | 2023-03-28 | 西南大学 | 一种基于电场强度调控的多孔材料渗透性定向调控方法及其产品 |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4450198A (en) * | 1980-01-28 | 1984-05-22 | Alza Corporation | Microporous film with polymer in pores for regulating passage of fluid |
JPS61274738A (ja) * | 1985-05-29 | 1986-12-04 | Mitsui Toatsu Chem Inc | マイクロカプセル |
GB8902909D0 (en) * | 1989-02-09 | 1989-03-30 | Unilever Plc | Coating process |
US5120349A (en) * | 1990-12-07 | 1992-06-09 | Landec Labs, Inc. | Microcapsule having temperature-dependent permeability profile |
US5260002A (en) * | 1991-12-23 | 1993-11-09 | Vanderbilt University | Method and apparatus for producing uniform polymeric spheres |
DE19519804A1 (de) * | 1995-05-31 | 1996-12-05 | Juergen Dr Schrezenmeir | Bioaktive Kapsel mit veränderlicher Hülle |
EP1064088B1 (de) * | 1998-03-19 | 2002-12-04 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | Herstellung von mit mehrlagen gestrichenen partikeln und hohlen schalen durch elektrostatische selbstorganisierung von nanokompositmehrlagen auf zersetzbaren schablonen |
EP1647270B1 (de) * | 1998-03-19 | 2009-06-17 | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. | Verfahren zum Aufbringen mehrerer Schichten von Beschichtungssubstanzen auf Templatpartikel |
US6756217B1 (en) * | 1998-05-29 | 2004-06-29 | Southern Illinois University | Glass composite materials containing alkoxosilane derivative having alterable charge, hydrophobic and hydrophilic groups |
ATE377449T1 (de) * | 1998-07-15 | 2007-11-15 | Max Planck Gesellschaft | Polyelektrolythüllen auf biologischen templaten |
WO2001037803A2 (en) * | 1999-11-15 | 2001-05-31 | Biocure, Inc. | Responsive polymeric hollow particles |
DE50103245D1 (de) * | 2000-08-02 | 2004-09-16 | Max Planck Gesellschaft | Polyelektrolytkapselherstellung durch oberflächenpräzipitation |
US20060029634A1 (en) * | 2004-08-06 | 2006-02-09 | Berg Michael C | Porous structures |
-
2001
- 2001-08-28 AT AT01980290T patent/ATE295156T1/de not_active IP Right Cessation
- 2001-08-28 WO PCT/EP2001/009908 patent/WO2002017888A2/en active IP Right Grant
- 2001-08-28 EP EP01980290A patent/EP1313455B1/de not_active Expired - Lifetime
- 2001-08-28 DE DE60110809T patent/DE60110809T2/de not_active Expired - Lifetime
- 2001-08-28 CA CA2420523A patent/CA2420523C/en not_active Expired - Fee Related
- 2001-08-28 JP JP2002522862A patent/JP2004507488A/ja active Pending
- 2001-08-28 US US10/363,472 patent/US20040013721A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
EP1313455B1 (de) | 2005-05-11 |
DE60110809T2 (de) | 2005-10-06 |
DE60110809D1 (de) | 2005-06-16 |
WO2002017888A9 (en) | 2003-05-15 |
JP2004507488A (ja) | 2004-03-11 |
CA2420523C (en) | 2010-05-25 |
EP1313455A2 (de) | 2003-05-28 |
WO2002017888A2 (en) | 2002-03-07 |
CA2420523A1 (en) | 2002-03-07 |
US20040013721A1 (en) | 2004-01-22 |
WO2002017888A3 (en) | 2002-07-25 |
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Legal Events
Date | Code | Title | Description |
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RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |