ATE291906T1 - Verpressbare guaifenesin zusammensetzungen und deren herstellungsverfahren - Google Patents

Verpressbare guaifenesin zusammensetzungen und deren herstellungsverfahren

Info

Publication number
ATE291906T1
ATE291906T1 AT02741904T AT02741904T ATE291906T1 AT E291906 T1 ATE291906 T1 AT E291906T1 AT 02741904 T AT02741904 T AT 02741904T AT 02741904 T AT02741904 T AT 02741904T AT E291906 T1 ATE291906 T1 AT E291906T1
Authority
AT
Austria
Prior art keywords
guaifenesin
pressable
production process
weight
compositions
Prior art date
Application number
AT02741904T
Other languages
English (en)
Inventor
Ajay Hasmukhlal Upadhyay
Original Assignee
Rhodia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhodia filed Critical Rhodia
Application granted granted Critical
Publication of ATE291906T1 publication Critical patent/ATE291906T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/075—Ethers or acetals
    • A61K31/085—Ethers or acetals having an ether linkage to aromatic ring nuclear carbon
    • A61K31/09—Ethers or acetals having an ether linkage to aromatic ring nuclear carbon having two or more such linkages
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pulmonology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Peptides Or Proteins (AREA)
AT02741904T 2001-06-12 2002-06-07 Verpressbare guaifenesin zusammensetzungen und deren herstellungsverfahren ATE291906T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/879,320 US20030012820A1 (en) 2001-06-12 2001-06-12 Compressible guaifenesin compositions, method for making same and method for making compressed guaifenesin dosage forms therefrom
PCT/US2002/018094 WO2002100389A2 (en) 2001-06-12 2002-06-07 Compressible guaifenesin compositions and method for producing them

Publications (1)

Publication Number Publication Date
ATE291906T1 true ATE291906T1 (de) 2005-04-15

Family

ID=25373900

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02741904T ATE291906T1 (de) 2001-06-12 2002-06-07 Verpressbare guaifenesin zusammensetzungen und deren herstellungsverfahren

Country Status (10)

Country Link
US (1) US20030012820A1 (de)
EP (1) EP1397125B1 (de)
CN (1) CN1269474C (de)
AT (1) ATE291906T1 (de)
AU (1) AU2002314972A1 (de)
CA (1) CA2450233C (de)
DE (1) DE60203498T2 (de)
ES (1) ES2240760T3 (de)
TW (1) TWI326217B (de)
WO (1) WO2002100389A2 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8012504B2 (en) * 2000-04-28 2011-09-06 Reckitt Benckiser Inc. Sustained release of guaifenesin combination drugs
US7838032B2 (en) * 2000-04-28 2010-11-23 Reckitt Benckiser Inc. Sustained release of guaifenesin
US7985420B2 (en) * 2000-04-28 2011-07-26 Reckitt Benckiser Inc. Sustained release of guaifenesin combination drugs
US6955821B2 (en) 2000-04-28 2005-10-18 Adams Laboratories, Inc. Sustained release formulations of guaifenesin and additional drug ingredients
CA2859174C (en) * 2011-12-12 2019-03-05 Orbis Biosciences, Inc. Sustained release particle formulations
CA3001337C (en) * 2015-10-09 2023-12-12 Reckitt Benckiser Llc Pharmaceutical formulation
US11202766B1 (en) * 2019-04-23 2021-12-21 ECI Pharmaceuticals, LLC Pharmaceutical compositions including hydrocodone bitartrate and guaifenesin

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3627583A (en) * 1969-04-29 1971-12-14 Sucrest Corp Direct compression vehicles
AU581177B2 (en) * 1983-05-31 1989-02-16 Choong-Gook Jang Dry direct compression compositions for controlled release dosage forms
US4798725A (en) * 1986-06-16 1989-01-17 Norwich Eaton Pharmaceuticals, Inc. Sustained release capsule
US5032406A (en) * 1989-02-21 1991-07-16 Norwich Eaton Pharmaceuticals, Inc. Dual-action tablet
US6623756B1 (en) * 2000-04-27 2003-09-23 Noveon Ip Holdings Corp. Directly compressed solid dosage articles
US6372252B1 (en) * 2000-04-28 2002-04-16 Adams Laboratories, Inc. Guaifenesin sustained release formulation and tablets

Also Published As

Publication number Publication date
EP1397125A2 (de) 2004-03-17
TWI326217B (en) 2010-06-21
CN1269474C (zh) 2006-08-16
WO2002100389A8 (en) 2003-04-24
DE60203498D1 (de) 2005-05-04
WO2002100389A3 (en) 2003-10-30
CA2450233A1 (en) 2002-12-19
WO2002100389A2 (en) 2002-12-19
CN1516579A (zh) 2004-07-28
US20030012820A1 (en) 2003-01-16
CA2450233C (en) 2012-12-18
AU2002314972A1 (en) 2002-12-23
EP1397125B1 (de) 2005-03-30
ES2240760T3 (es) 2005-10-16
DE60203498T2 (de) 2006-01-26

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Legal Events

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