ATE286717T1 - Biologisch aktive verbindungen enthaltende multilamellare koaleszenzvesikel (mlcv) - Google Patents
Biologisch aktive verbindungen enthaltende multilamellare koaleszenzvesikel (mlcv)Info
- Publication number
- ATE286717T1 ATE286717T1 AT98950869T AT98950869T ATE286717T1 AT E286717 T1 ATE286717 T1 AT E286717T1 AT 98950869 T AT98950869 T AT 98950869T AT 98950869 T AT98950869 T AT 98950869T AT E286717 T1 ATE286717 T1 AT E286717T1
- Authority
- AT
- Austria
- Prior art keywords
- biologically active
- vesicles
- active compound
- multilamellar
- mlcvs
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 6
- 238000004581 coalescence Methods 0.000 title abstract 2
- 230000018044 dehydration Effects 0.000 abstract 2
- 238000006297 dehydration reaction Methods 0.000 abstract 2
- 150000002632 lipids Chemical class 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 239000000203 mixture Substances 0.000 abstract 2
- 239000003960 organic solvent Substances 0.000 abstract 2
- 238000010257 thawing Methods 0.000 abstract 2
- 239000002691 unilamellar liposome Substances 0.000 abstract 2
- 239000012062 aqueous buffer Substances 0.000 abstract 1
- 239000007864 aqueous solution Substances 0.000 abstract 1
- 230000000887 hydrating effect Effects 0.000 abstract 1
- 239000002502 liposome Substances 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 238000002844 melting Methods 0.000 abstract 1
- 230000008018 melting Effects 0.000 abstract 1
- 230000007704 transition Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
- A61K9/1277—Preparation processes; Proliposomes
- A61K9/1278—Post-loading, e.g. by ion or pH gradient
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
- A61K9/1277—Preparation processes; Proliposomes
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S977/00—Nanotechnology
- Y10S977/902—Specified use of nanostructure
- Y10S977/904—Specified use of nanostructure for medical, immunological, body treatment, or diagnosis
- Y10S977/906—Drug delivery
- Y10S977/907—Liposome
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Dispersion Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Manufacturing Of Micro-Capsules (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US6060697P | 1997-10-01 | 1997-10-01 | |
| PCT/US1998/020780 WO1999016426A2 (en) | 1997-10-01 | 1998-10-01 | Multilamellar coalescence vesicles (mlcv) containing biologically active compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE286717T1 true ATE286717T1 (de) | 2005-01-15 |
Family
ID=22030591
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT98950869T ATE286717T1 (de) | 1997-10-01 | 1998-10-01 | Biologisch aktive verbindungen enthaltende multilamellare koaleszenzvesikel (mlcv) |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US6544549B1 (https=) |
| EP (1) | EP1019026B1 (https=) |
| JP (1) | JP2001517693A (https=) |
| AT (1) | ATE286717T1 (https=) |
| AU (1) | AU745000B2 (https=) |
| CA (1) | CA2305533C (https=) |
| DE (1) | DE69828624T2 (https=) |
| IN (1) | IN190388B (https=) |
| WO (1) | WO1999016426A2 (https=) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPWO2006095798A1 (ja) * | 2005-03-09 | 2008-08-14 | サンスター株式会社 | フィトステロールを含んだリポソームを含有する抗癌用経口組成物、該リポソームによる癌の予防又は治療 |
| WO2007021822A2 (en) * | 2005-08-09 | 2007-02-22 | The Research Foundation Of State Of University Of New York At Buffalo | Compositions and methods of preparation of liposomal microparticulate il-12 |
| US8597678B2 (en) | 2005-12-30 | 2013-12-03 | Dermazone Solutions, Inc. | Nanolipidic particles |
| US20140271782A1 (en) | 2013-03-15 | 2014-09-18 | Dermazone Solutions, Inc. | Method for preparing nanolipids with encapsulated alcohol |
| US9283184B2 (en) | 2008-11-24 | 2016-03-15 | Massachusetts Institute Of Technology | Methods and compositions for localized agent delivery |
| US20100323018A1 (en) * | 2009-06-17 | 2010-12-23 | Massachusetts Institute Of Technology | Branched DNA/RNA monomers and uses thereof |
| US20100324124A1 (en) * | 2009-06-17 | 2010-12-23 | Massachusetts Institute Of Technology | Compositions and methods relating to DNA-based particles |
| US9149432B2 (en) | 2010-03-19 | 2015-10-06 | Massachusetts Institute Of Technology | Lipid vesicle compositions and methods of use |
| US20110229556A1 (en) * | 2010-03-19 | 2011-09-22 | Massachusetts Institute Of Technology | Lipid-coated polymer particles for immune stimulation |
| JP5686886B2 (ja) | 2010-03-19 | 2015-03-18 | マサチューセッツ インスチテュート オブ テクノロジーＭａｓｓａｃｈｕｓｅｔｔｓ Ｉｎｓｔｉｔｕｔｅ Ｏｆ Ｔｅｃｈｎｏｌｏｇｙ | 脂質小胞組成物及び使用方法 |
| CN102654505A (zh) * | 2012-05-16 | 2012-09-05 | 江苏省原子医学研究所 | 一种检测il-2-hsa的时间分辨荧光免疫分析试剂盒及其检测方法 |
| ES2641375T3 (es) * | 2012-11-02 | 2017-11-08 | Cytuvax | Composición que comprende macroagregados de citoquinas |
| US9770415B2 (en) * | 2012-11-27 | 2017-09-26 | Southwest Research Institute | Delivery substrates from aligned polymer biomaterials for tissue repair |
| EP3049114B1 (en) | 2013-09-27 | 2021-11-10 | Massachusetts Institute of Technology | Carrier-free biologically-active protein nanostructures |
| AU2016256979B2 (en) | 2015-05-04 | 2021-01-28 | Genfit | Method for preparing transmembrane pH-gradient vesicles |
| CN108990413A (zh) | 2015-08-12 | 2018-12-11 | 麻省理工学院 | 纳米颗粒的细胞表面偶联 |
| JP7185530B2 (ja) | 2016-06-13 | 2022-12-07 | トルク セラピューティクス， インコーポレイテッド | 免疫細胞機能を促進するための方法および組成物 |
| JP7285828B2 (ja) | 2017-09-05 | 2023-06-02 | トルク セラピューティクス， インコーポレイテッド | 治療用タンパク質組成物ならびにその作製および使用方法 |
| US20200078427A1 (en) | 2018-09-06 | 2020-03-12 | NuVessl, Inc. | Cannabis Sativa Derived Formulation for Transmucosal and Transdermal Delivery |
| US11458092B2 (en) | 2018-12-14 | 2022-10-04 | NuVessl, Inc. | Composition with enhanced passenger molecule loading |
| EP4099988A4 (en) * | 2020-02-05 | 2024-03-13 | University of Florida Research Foundation, Incorporated | Rna-loaded nanoparticles and use thereof for the treatment of cancer |
| EP4209586B1 (en) * | 2020-09-04 | 2025-10-29 | Daegu Gyeongbuk Institute Of Science and Technology | Extracellular vesicle expressing cytokine and antibody, method for producing same, and use thereof |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH04356421A (ja) | 1991-03-06 | 1992-12-10 | Green Cross Corp:The | プロスタグランジン類含有脂肪小体組成物 |
| EP0918539B1 (en) * | 1996-02-16 | 2005-10-19 | Biomira Usa Inc. | Vaccine for b-cell malignancies |
-
1998
- 1998-01-01 IN IN2930DE1998 patent/IN190388B/en unknown
- 1998-10-01 AT AT98950869T patent/ATE286717T1/de not_active IP Right Cessation
- 1998-10-01 JP JP2000513564A patent/JP2001517693A/ja active Pending
- 1998-10-01 CA CA002305533A patent/CA2305533C/en not_active Expired - Fee Related
- 1998-10-01 WO PCT/US1998/020780 patent/WO1999016426A2/en not_active Ceased
- 1998-10-01 DE DE69828624T patent/DE69828624T2/de not_active Expired - Lifetime
- 1998-10-01 EP EP98950869A patent/EP1019026B1/en not_active Expired - Lifetime
- 1998-10-01 US US09/164,350 patent/US6544549B1/en not_active Expired - Lifetime
- 1998-10-01 AU AU96800/98A patent/AU745000B2/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| IN190388B (https=) | 2003-07-26 |
| CA2305533A1 (en) | 1999-04-08 |
| DE69828624D1 (de) | 2005-02-17 |
| EP1019026B1 (en) | 2005-01-12 |
| JP2001517693A (ja) | 2001-10-09 |
| AU745000B2 (en) | 2002-03-07 |
| EP1019026A2 (en) | 2000-07-19 |
| US6544549B1 (en) | 2003-04-08 |
| WO1999016426A3 (en) | 1999-06-17 |
| WO1999016426A2 (en) | 1999-04-08 |
| DE69828624T2 (de) | 2005-12-22 |
| CA2305533C (en) | 2009-12-01 |
| AU9680098A (en) | 1999-04-23 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |