ATE277051T1 - Verfahren zur herstellung von debromohymenialdisin und deren analogen - Google Patents

Verfahren zur herstellung von debromohymenialdisin und deren analogen

Info

Publication number
ATE277051T1
ATE277051T1 AT00947544T AT00947544T ATE277051T1 AT E277051 T1 ATE277051 T1 AT E277051T1 AT 00947544 T AT00947544 T AT 00947544T AT 00947544 T AT00947544 T AT 00947544T AT E277051 T1 ATE277051 T1 AT E277051T1
Authority
AT
Austria
Prior art keywords
compound
dbh
converted
hydrogen
hymenin
Prior art date
Application number
AT00947544T
Other languages
English (en)
Inventor
David A Horne
Kenichi Yakushijin
Original Assignee
Oregon State
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Oregon State filed Critical Oregon State
Application granted granted Critical
Publication of ATE277051T1 publication Critical patent/ATE277051T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT00947544T 1999-07-20 2000-07-19 Verfahren zur herstellung von debromohymenialdisin und deren analogen ATE277051T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/357,687 US6211361B1 (en) 1999-07-20 1999-07-20 Method for making debromohymenialdisine and analogs thereof
PCT/US2000/019704 WO2001005794A2 (en) 1999-07-20 2000-07-19 Method for making debromohymenialdisine and analogs thereof

Publications (1)

Publication Number Publication Date
ATE277051T1 true ATE277051T1 (de) 2004-10-15

Family

ID=23406630

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00947544T ATE277051T1 (de) 1999-07-20 2000-07-19 Verfahren zur herstellung von debromohymenialdisin und deren analogen

Country Status (12)

Country Link
US (1) US6211361B1 (de)
EP (1) EP1200438B1 (de)
JP (1) JP2003505392A (de)
AT (1) ATE277051T1 (de)
AU (1) AU6112800A (de)
BR (1) BR0012599A (de)
CA (1) CA2379847A1 (de)
DE (1) DE60014103D1 (de)
IL (1) IL147728A0 (de)
MX (1) MXPA02000706A (de)
WO (1) WO2001005794A2 (de)
ZA (1) ZA200201159B (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2003297431A1 (en) * 2002-12-20 2004-07-22 Pharmacia Corporation Mitogen activated protein kinase-activated protein kinase-2 inhibiting compounds
WO2004098520A2 (en) * 2003-05-01 2004-11-18 Irm Llc Compounds and compositions as protein kinase inhibitors
WO2004103958A2 (en) * 2003-05-19 2004-12-02 Michigan State University Preparation of hymenialdisine derivatives and use thereof
US8304408B2 (en) * 2007-05-24 2012-11-06 The Regents Of The University Of California Wnt signaling inhibitors, and methods for making and using them
US10288506B2 (en) * 2016-10-19 2019-05-14 Steering Solutions Ip Holding Corporation Integrated torque sensor in controller board and EPS system incorporating the same

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU3731293A (en) * 1992-02-24 1993-09-13 Smithkline Beecham Corporation Protein kinase c inhibitor
JP3714685B2 (ja) * 1994-05-18 2005-11-09 第一サントリーファーマ株式会社 ハイメニアルディシン及びその誘導体並びにそれらの合成中間体の製造法並びにその合成中間体
US5591740A (en) * 1995-06-07 1997-01-07 Osteoarthritis Sciences, Incorporated Use of debromohymenialdisine for treating osteoarthritis

Also Published As

Publication number Publication date
EP1200438B1 (de) 2004-09-22
WO2001005794A3 (en) 2001-07-19
ZA200201159B (en) 2003-08-27
JP2003505392A (ja) 2003-02-12
WO2001005794A2 (en) 2001-01-25
BR0012599A (pt) 2002-09-17
AU6112800A (en) 2001-02-05
DE60014103D1 (de) 2004-10-28
IL147728A0 (en) 2002-08-14
EP1200438A2 (de) 2002-05-02
US6211361B1 (en) 2001-04-03
CA2379847A1 (en) 2001-01-25
MXPA02000706A (es) 2002-07-02

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Legal Events

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