ATE276830T1 - Modulare reaktionsblockanordnung mit thermoelektrischer kühlung und heizung - Google Patents
Modulare reaktionsblockanordnung mit thermoelektrischer kühlung und heizungInfo
- Publication number
- ATE276830T1 ATE276830T1 AT99201812T AT99201812T ATE276830T1 AT E276830 T1 ATE276830 T1 AT E276830T1 AT 99201812 T AT99201812 T AT 99201812T AT 99201812 T AT99201812 T AT 99201812T AT E276830 T1 ATE276830 T1 AT E276830T1
- Authority
- AT
- Austria
- Prior art keywords
- exterior wall
- reaction
- heating
- heat
- thermoelectric module
- Prior art date
Links
- 238000010438 heat treatment Methods 0.000 title abstract 3
- 238000001816 cooling Methods 0.000 abstract 2
- 230000000712 assembly Effects 0.000 abstract 1
- 238000000429 assembly Methods 0.000 abstract 1
- 239000012530 fluid Substances 0.000 abstract 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L7/00—Heating or cooling apparatus; Heat insulating devices
- B01L7/52—Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J19/0046—Sequential or parallel reactions, e.g. for the synthesis of polypeptides or polynucleotides; Apparatus and devices for combinatorial chemistry or for making molecular arrays
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00279—Features relating to reactor vessels
- B01J2219/00281—Individual reactor vessels
- B01J2219/00283—Reactor vessels with top opening
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00279—Features relating to reactor vessels
- B01J2219/00306—Reactor vessels in a multiple arrangement
- B01J2219/00308—Reactor vessels in a multiple arrangement interchangeably mounted in racks or blocks
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00279—Features relating to reactor vessels
- B01J2219/00306—Reactor vessels in a multiple arrangement
- B01J2219/00308—Reactor vessels in a multiple arrangement interchangeably mounted in racks or blocks
- B01J2219/0031—Reactor vessels in a multiple arrangement interchangeably mounted in racks or blocks the racks or blocks being mounted in stacked arrangements
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00279—Features relating to reactor vessels
- B01J2219/00331—Details of the reactor vessels
- B01J2219/00333—Closures attached to the reactor vessels
- B01J2219/00344—Caps
- B01J2219/00346—Screw-caps
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00479—Means for mixing reactants or products in the reaction vessels
- B01J2219/00481—Means for mixing reactants or products in the reaction vessels by the use of moving stirrers within the reaction vessels
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00495—Means for heating or cooling the reaction vessels
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00585—Parallel processes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/0068—Means for controlling the apparatus of the process
- B01J2219/00686—Automatic
- B01J2219/00689—Automatic using computers
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B60/00—Apparatus specially adapted for use in combinatorial chemistry or with libraries
- C40B60/14—Apparatus specially adapted for use in combinatorial chemistry or with libraries for creating libraries
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Clinical Laboratory Science (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Physical Or Chemical Processes And Apparatus (AREA)
- Measuring Temperature Or Quantity Of Heat (AREA)
- Control Of Temperature (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/090,021 US6086831A (en) | 1998-06-10 | 1998-06-10 | Modular reaction block assembly with thermoelectric cooling and heating |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE276830T1 true ATE276830T1 (de) | 2004-10-15 |
Family
ID=22220810
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT99201812T ATE276830T1 (de) | 1998-06-10 | 1999-06-08 | Modulare reaktionsblockanordnung mit thermoelektrischer kühlung und heizung |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US6086831A (de) |
| EP (1) | EP0963791B1 (de) |
| JP (1) | JP2000024492A (de) |
| AT (1) | ATE276830T1 (de) |
| DE (1) | DE69920326T2 (de) |
Families Citing this family (49)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6864092B1 (en) | 1998-08-13 | 2005-03-08 | Symyx Technologies, Inc. | Parallel reactor with internal sensing and method of using same |
| US6913934B2 (en) * | 1998-08-13 | 2005-07-05 | Symyx Technologies, Inc. | Apparatus and methods for parallel processing of multiple reaction mixtures |
| US6548026B1 (en) * | 1998-08-13 | 2003-04-15 | Symyx Technologies, Inc. | Parallel reactor with internal sensing and method of using same |
| US6528026B2 (en) | 1998-08-13 | 2003-03-04 | Symyx Technologies, Inc. | Multi-temperature modular reactor and method of using same |
| US6759014B2 (en) * | 2001-01-26 | 2004-07-06 | Symyx Technologies, Inc. | Apparatus and methods for parallel processing of multiple reaction mixtures |
| US6306658B1 (en) | 1998-08-13 | 2001-10-23 | Symyx Technologies | Parallel reactor with internal sensing |
| US6455316B1 (en) | 1998-08-13 | 2002-09-24 | Symyx Technologies, Inc. | Parallel reactor with internal sensing and method of using same |
| GB9826237D0 (en) * | 1998-11-30 | 1999-01-20 | Hybaid Ltd | Thermal cycler |
| US6485692B1 (en) | 1998-12-04 | 2002-11-26 | Symyx Technologies, Inc. | Continuous feed parallel reactor |
| JP2000274872A (ja) * | 1999-03-19 | 2000-10-06 | Matsushita Refrig Co Ltd | 熱電モジュールを内蔵するマニホールド |
| GB9915953D0 (en) * | 1999-07-07 | 1999-09-08 | Stem Corp Limited | Improvements relating to multi-station reaction apparatus |
| WO2001034290A2 (en) | 1999-11-09 | 2001-05-17 | Sri International | Array for generating combinatorial libraries |
| US7033840B1 (en) | 1999-11-09 | 2006-04-25 | Sri International | Reaction calorimeter and differential scanning calorimeter for the high-throughput synthesis, screening and characterization of combinatorial libraries |
| FR2806323B1 (fr) | 2000-03-17 | 2002-10-11 | Centre Nat Rech Scient | Module et appareil pour la synthese de molecules organiques ou autres |
| US6994827B2 (en) * | 2000-06-03 | 2006-02-07 | Symyx Technologies, Inc. | Parallel semicontinuous or continuous reactors |
| DE10036633B4 (de) * | 2000-07-27 | 2005-03-10 | Hte Ag The High Throughput Exp | Anordnung in modularer Bauweise und Verfahren zur paralellen Testung einer Mehrzahl von Bausteinen einer Materialbibliothek |
| US6692708B2 (en) | 2001-04-05 | 2004-02-17 | Symyx Technologies, Inc. | Parallel reactor for sampling and conducting in situ flow-through reactions and a method of using same |
| US6676905B2 (en) | 2001-06-07 | 2004-01-13 | Aventis Pharmaceuticals Inc. | Multi-well plate with perimeteral heat reservoir |
| US6582116B2 (en) | 2001-09-24 | 2003-06-24 | Symyx Technologies, Inc. | Apparatus and method for mixing small volumes of reaction materials |
| US20030190260A1 (en) * | 2002-04-05 | 2003-10-09 | Symyx Technologies, Inc. | Combinatorial chemistry reactor system |
| US20040072334A1 (en) * | 2002-10-15 | 2004-04-15 | The Regents Of The University Of California | Thermal cycler |
| US20040132209A1 (en) * | 2003-01-03 | 2004-07-08 | Alexanian Ara J. | Multi-chamber treatment apparatus and method |
| WO2004062779A2 (en) * | 2003-01-09 | 2004-07-29 | Argonaut Technologies, Inc. | Multi-channel parallel module temperature control system |
| US20040136873A1 (en) * | 2003-01-09 | 2004-07-15 | Argonaut Technologies, Inc. | Modular reactor system |
| US20050282266A1 (en) * | 2004-06-21 | 2005-12-22 | Chun-Nan Teng | Polymerase chain reactor |
| US7587901B2 (en) | 2004-12-20 | 2009-09-15 | Amerigon Incorporated | Control system for thermal module in vehicle |
| DE102006011822B4 (de) * | 2006-03-13 | 2010-05-20 | Technische Universität Darmstadt | Reaktor für heterogene Gasphasenreaktionen, Vorrichtung zum Testen von Katalysatoren für heterogene Gasphasenreaktionen und Verfahren zum Testen solcher Katalysatoren |
| US7848848B2 (en) * | 2006-04-28 | 2010-12-07 | Freeslate, Inc. | Robotic station for capturing both image and weight of a sample |
| US8222511B2 (en) * | 2006-08-03 | 2012-07-17 | Gentherm | Thermoelectric device |
| US20080087316A1 (en) | 2006-10-12 | 2008-04-17 | Masa Inaba | Thermoelectric device with internal sensor |
| WO2009036077A1 (en) | 2007-09-10 | 2009-03-19 | Amerigon, Inc. | Operational control schemes for ventilated seat or bed assemblies |
| KR20170064568A (ko) | 2008-02-01 | 2017-06-09 | 젠썸 인코포레이티드 | 열전 소자용 응결 센서 및 습도 센서 |
| CN102098947B (zh) | 2008-07-18 | 2014-12-10 | 阿美里根公司 | 气候受控床组件 |
| GB201016014D0 (en) * | 2010-09-24 | 2010-11-10 | Epistem Ltd | Thermal cycler |
| WO2013052823A1 (en) | 2011-10-07 | 2013-04-11 | Gentherm Incorporated | Thermoelectric device controls and methods |
| US9989267B2 (en) | 2012-02-10 | 2018-06-05 | Gentherm Incorporated | Moisture abatement in heating operation of climate controlled systems |
| US20150243870A1 (en) * | 2013-04-23 | 2015-08-27 | Hi-Z Technology, Inc. | Compact high power density thermoelectric generator |
| US9662962B2 (en) | 2013-11-05 | 2017-05-30 | Gentherm Incorporated | Vehicle headliner assembly for zonal comfort |
| US9284596B2 (en) * | 2014-02-13 | 2016-03-15 | Battelle Energy Alliance, Llc | Methods for determining enzymatic activity comprising heating and agitation of closed volumes |
| KR102252584B1 (ko) | 2014-02-14 | 2021-05-14 | 젠썸 인코포레이티드 | 전도식 대류식 기온 제어 조립체 |
| US10179899B2 (en) | 2014-06-18 | 2019-01-15 | Luminex Corporation | Apparatus and methods for magnetic mixing |
| US11857004B2 (en) | 2014-11-14 | 2024-01-02 | Gentherm Incorporated | Heating and cooling technologies |
| EP3218942B1 (de) | 2014-11-14 | 2020-02-26 | Charles J. Cauchy | Heiz- und kühltechnologien |
| US11639816B2 (en) | 2014-11-14 | 2023-05-02 | Gentherm Incorporated | Heating and cooling technologies including temperature regulating pad wrap and technologies with liquid system |
| TWI582885B (zh) * | 2015-12-30 | 2017-05-11 | 國立中央大學 | 低溫製造組織工程用支架的平台結構及低溫製造組織工程用支架的製造方法 |
| AU2018291024B2 (en) | 2017-06-30 | 2023-07-27 | Sri International | Apparatuses for reaction screening and optimization, and methods thereof |
| US11223004B2 (en) | 2018-07-30 | 2022-01-11 | Gentherm Incorporated | Thermoelectric device having a polymeric coating |
| JP7608337B2 (ja) | 2018-11-30 | 2025-01-06 | ジェンサーム インコーポレイテッド | 熱電調整システム及び方法 |
| US11152557B2 (en) | 2019-02-20 | 2021-10-19 | Gentherm Incorporated | Thermoelectric module with integrated printed circuit board |
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| US3143167A (en) * | 1961-05-19 | 1964-08-04 | Tung Sol Electric Inc | Temperature controlled enclosure for testing purposes |
| US4066365A (en) * | 1976-05-28 | 1978-01-03 | The Perkin-Elmer Corporation | Temperature control apparatus |
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| US4312835A (en) * | 1980-04-21 | 1982-01-26 | American Cyanamid Company | Thermal control means for liquid chromatograph samples |
| US4517338A (en) * | 1983-06-20 | 1985-05-14 | Chiron Corporation | Multiple reactor system and method for polynucleotide synthesis |
| US4598049A (en) * | 1983-08-31 | 1986-07-01 | Systec Inc. | General purpose gene synthesizer |
| US4746490A (en) * | 1983-09-22 | 1988-05-24 | Saneii Hossain H | Solid phase peptide synthesizer |
| JPS60105691A (ja) * | 1983-11-14 | 1985-06-11 | Nippon Zeon Co Ltd | ポリヌクレオチド合成装置 |
| US5656493A (en) * | 1985-03-28 | 1997-08-12 | The Perkin-Elmer Corporation | System for automated performance of the polymerase chain reaction |
| FR2582655B1 (fr) * | 1985-06-03 | 1988-12-23 | Centre Nat Rech Scient | Multi-synthetiseur de peptides semi-automatique en phase solide |
| US4640023A (en) * | 1985-07-05 | 1987-02-03 | Director General Of Agency Of Industrial Science And Technology | Apparatus for manufacturing powdered silicon nitride |
| DE3525860A1 (de) * | 1985-07-19 | 1987-01-29 | Egbert Dr Brandau | Thermostat |
| EP0342155A3 (de) * | 1988-05-13 | 1990-06-27 | Agrogen-Stiftung | Laboratoriumsgerät zum wahlweisen Heizen und Kühlen |
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| US5143854A (en) * | 1989-06-07 | 1992-09-01 | Affymax Technologies N.V. | Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof |
| JPH03297377A (ja) * | 1990-04-12 | 1991-12-27 | Seiko Instr Inc | 自動反応装置 |
| US5252296A (en) * | 1990-05-15 | 1993-10-12 | Chiron Corporation | Method and apparatus for biopolymer synthesis |
| KR100236506B1 (ko) * | 1990-11-29 | 2000-01-15 | 퍼킨-엘머시터스인스트루먼츠 | 폴리머라제 연쇄 반응 수행 장치 |
| US5789258A (en) * | 1991-06-10 | 1998-08-04 | Midwest Research Institute | Method for generating vapor streams |
| JPH0720546B2 (ja) * | 1991-08-26 | 1995-03-08 | 株式会社島津製作所 | 多種品目同時化学反応装置 |
| FI915731A0 (fi) * | 1991-12-05 | 1991-12-05 | Derek Henry Potter | Foerfarande och anordning foer reglering av temperaturen i ett flertal prov. |
| DE4231702C2 (de) * | 1992-09-22 | 1995-05-24 | Litef Gmbh | Thermoelektrische, beheizbare Kühlkammer |
| US5601141A (en) * | 1992-10-13 | 1997-02-11 | Intelligent Automation Systems, Inc. | High throughput thermal cycler |
| JPH06281655A (ja) * | 1993-03-25 | 1994-10-07 | Olympus Optical Co Ltd | 自動分析装置 |
| US5380495A (en) * | 1993-08-27 | 1995-01-10 | Chang; Heng-Wei | Solid phase peptide synthesizer |
| CA2130517C (en) * | 1993-09-10 | 1999-10-05 | Walter Fassbind | Array of reaction containers for an apparatus for automatic performance of temperature cycles |
| US5503805A (en) * | 1993-11-02 | 1996-04-02 | Affymax Technologies N.V. | Apparatus and method for parallel coupling reactions |
| US5716584A (en) * | 1995-09-07 | 1998-02-10 | Pathogenesis Corporation | Device for the synthesis of compounds in an array |
| DE19602464B4 (de) * | 1996-01-24 | 2006-05-04 | Rapp, Wolfgang, Dr. | Vorrichtung zur multiplen, gleichzeitigen und parallelen Synthese chemischer Verbindungen und zur diskreten Weiterbehandlung von Aliquoten |
| JPH09313926A (ja) * | 1996-05-31 | 1997-12-09 | Orion Mach Co Ltd | 半導体処理液の熱交換器 |
| US5802856A (en) * | 1996-07-31 | 1998-09-08 | Stanford University | Multizone bake/chill thermal cycling module |
| US5866342A (en) * | 1996-09-27 | 1999-02-02 | Glaxo Group Limited | Systems and methods for the synthesis of organic compounds |
| AU7477398A (en) * | 1997-05-09 | 1998-11-27 | Regents Of The University Of California, The | Peltier-assisted microfabricated reaction chambers for thermal cycling |
-
1998
- 1998-06-10 US US09/090,021 patent/US6086831A/en not_active Expired - Fee Related
-
1999
- 1999-06-08 EP EP99201812A patent/EP0963791B1/de not_active Expired - Lifetime
- 1999-06-08 DE DE69920326T patent/DE69920326T2/de not_active Expired - Fee Related
- 1999-06-08 AT AT99201812T patent/ATE276830T1/de not_active IP Right Cessation
- 1999-06-10 JP JP11164193A patent/JP2000024492A/ja not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| JP2000024492A (ja) | 2000-01-25 |
| DE69920326D1 (de) | 2004-10-28 |
| EP0963791B1 (de) | 2004-09-22 |
| EP0963791A2 (de) | 1999-12-15 |
| US6086831A (en) | 2000-07-11 |
| DE69920326T2 (de) | 2006-03-02 |
| EP0963791A3 (de) | 2000-09-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 0963791 Country of ref document: EP |
|
| REN | Ceased due to non-payment of the annual fee |