ATE259677T1 - STRUCTURED REACTION SUBSTRATE - Google Patents

STRUCTURED REACTION SUBSTRATE

Info

Publication number
ATE259677T1
ATE259677T1 AT00966127T AT00966127T ATE259677T1 AT E259677 T1 ATE259677 T1 AT E259677T1 AT 00966127 T AT00966127 T AT 00966127T AT 00966127 T AT00966127 T AT 00966127T AT E259677 T1 ATE259677 T1 AT E259677T1
Authority
AT
Austria
Prior art keywords
reaction substrate
relates
polymer material
structured reaction
structured
Prior art date
Application number
AT00966127T
Other languages
German (de)
Inventor
Susanne Brakmann
Helmut Peuker
Wolfgang Simm
Ulrich Kettling
Andre Koltermann
Jens Stephan
Thorsten Winkler
Klaus Doerre
Manfred Eigen
Original Assignee
Evotec Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Evotec Ag filed Critical Evotec Ag
Application granted granted Critical
Publication of ATE259677T1 publication Critical patent/ATE259677T1/en

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
    • B01L3/5085—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates
    • B01L3/50853—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates with covers or lids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0819—Microarrays; Biochips
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/12—Specific details about materials
    • B01L2300/123—Flexible; Elastomeric

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Steering Control In Accordance With Driving Conditions (AREA)
  • Saccharide Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Micromachines (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Laminated Bodies (AREA)

Abstract

The invention relates to a reaction substrate (20) comprised of a base part (10) and of a flexible compartment layer (21) which is made of a polymer material and which is provided with predetermined compartment structures (30) for forming sample compartments. According to the invention, the polymer material is a viscoelastic polymer composition (e.g. silicone rubber) which has an inherent adhesive property with regard to substrates made of glass, plastic, metal or of semiconductors. The invention also relates to a tool for producing the reaction substrate.
AT00966127T 1999-10-06 2000-10-06 STRUCTURED REACTION SUBSTRATE ATE259677T1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19948087A DE19948087B4 (en) 1999-10-06 1999-10-06 Process for the preparation of a reaction substrate
PCT/EP2000/009808 WO2001024933A1 (en) 1999-10-06 2000-10-06 Structured reaction substrate and method for producing the same

Publications (1)

Publication Number Publication Date
ATE259677T1 true ATE259677T1 (en) 2004-03-15

Family

ID=7924652

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00966127T ATE259677T1 (en) 1999-10-06 2000-10-06 STRUCTURED REACTION SUBSTRATE

Country Status (6)

Country Link
EP (1) EP1218105B1 (en)
JP (1) JP2003511654A (en)
AT (1) ATE259677T1 (en)
DE (2) DE19948087B4 (en)
DK (1) DK1218105T3 (en)
WO (1) WO2001024933A1 (en)

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DE60125598T2 (en) * 2001-06-08 2007-10-04 Centre National De La Recherche Scientifique METHOD FOR PRODUCING A MICROFLUIDITY STRUCTURE, IN PARTICULAR A "BIOCHIP", AND STRUCTURE PRODUCED THEREFOR
DE10142788A1 (en) * 2001-08-31 2003-03-27 Advalytix Ag To form a thin liquid film on a carrier, for chemical/biological sample analysis, the flat carrier is shrouded by a spaced cover, for liquid to pass through a passage drilling and spread by capillary action
AU2002360499A1 (en) 2001-12-05 2003-06-17 University Of Washington Microfluidic device and surface decoration process for solid phase affinity binding assays
DE10316723A1 (en) * 2003-04-09 2004-11-18 Siemens Ag Test slide with sample wells, forming sealed reaction chamber with casing, also includes bonded seal forming resting surface for casing
JP3727026B2 (en) * 2003-04-10 2005-12-14 博行 野地 Micro chamber used for detecting single-molecule enzyme activity and method for preparing droplets of 1000 fL or less
US7335504B2 (en) 2003-06-18 2008-02-26 Direvo Biotechnology Ag Engineered enzymes and uses thereof
DE10336849A1 (en) 2003-08-11 2005-03-10 Thinxxs Gmbh flow cell
DE10356838A1 (en) 2003-12-05 2005-07-21 Tecpharma Licensing Ag sealing element
JP2006162538A (en) * 2004-12-10 2006-06-22 Seiko Instruments Inc Apparatus for measuring trace mass
DE102005003966A1 (en) * 2005-01-27 2006-08-10 Ehrfeld Mikrotechnik Bts Gmbh Apparatus for the continuous implementation of photochemical processes with low optical layer thicknesses, narrow residence time distribution and high throughputs
US9388374B2 (en) 2005-07-07 2016-07-12 Emd Millipore Corporation Microfluidic cell culture systems
US9354156B2 (en) 2007-02-08 2016-05-31 Emd Millipore Corporation Microfluidic particle analysis method, device and system
US8257964B2 (en) 2006-01-04 2012-09-04 Cell ASIC Microwell cell-culture device and fabrication method
ES2865180T3 (en) 2005-07-07 2021-10-15 Univ California Apparatus for cell culture formation
US9637715B2 (en) 2005-07-07 2017-05-02 Emd Millipore Corporation Cell culture and invasion assay method and system
WO2007097229A1 (en) * 2006-02-20 2007-08-30 Shimadzu Corporation Reaction kit
WO2007139056A1 (en) * 2006-06-01 2007-12-06 Shimadzu Corporation Dispensing tip, reaction kit using the same, and dispensing tip drive mechanism
US20080069732A1 (en) * 2006-09-20 2008-03-20 Robert Yi Diagnostic test system
EP3173787B1 (en) 2008-01-03 2021-06-02 EMD Millipore Corporation Cell culture array system for automated assays and methods of operation and manufacture thereof
US9353342B2 (en) 2010-01-21 2016-05-31 Emd Millipore Corporation Cell culture and gradient migration assay methods and devices
US10526572B2 (en) 2011-04-01 2020-01-07 EMD Millipore Corporaticn Cell culture and invasion assay method and system
JP6232383B2 (en) 2011-12-03 2017-11-15 イー・エム・デイー・ミリポア・コーポレイシヨン Microincubation system and method for microfluidic cell culture
DE102017004567A1 (en) * 2017-05-11 2018-11-15 Innome Gmbh Device for the analysis of biological samples

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Also Published As

Publication number Publication date
DK1218105T3 (en) 2004-06-21
DE19948087A1 (en) 2001-05-03
DE50005348D1 (en) 2004-03-25
DE19948087B4 (en) 2008-04-17
EP1218105A1 (en) 2002-07-03
WO2001024933A1 (en) 2001-04-12
EP1218105B1 (en) 2004-02-18
JP2003511654A (en) 2003-03-25

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Legal Events

Date Code Title Description
REN Ceased due to non-payment of the annual fee