ATE258163T1 - Verbesserte arylamin-synthese - Google Patents
Verbesserte arylamin-syntheseInfo
- Publication number
- ATE258163T1 ATE258163T1 AT99937293T AT99937293T ATE258163T1 AT E258163 T1 ATE258163 T1 AT E258163T1 AT 99937293 T AT99937293 T AT 99937293T AT 99937293 T AT99937293 T AT 99937293T AT E258163 T1 ATE258163 T1 AT E258163T1
- Authority
- AT
- Austria
- Prior art keywords
- imine
- arylamin
- synthesis
- improved
- preparation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
- C07C227/04—Formation of amino groups in compounds containing carboxyl groups
- C07C227/06—Formation of amino groups in compounds containing carboxyl groups by addition or substitution reactions, without increasing the number of carbon atoms in the carbon skeleton of the acid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
- C07C209/04—Preparation of compounds containing amino groups bound to a carbon skeleton by substitution of functional groups by amino groups
- C07C209/06—Preparation of compounds containing amino groups bound to a carbon skeleton by substitution of functional groups by amino groups by substitution of halogen atoms
- C07C209/10—Preparation of compounds containing amino groups bound to a carbon skeleton by substitution of functional groups by amino groups by substitution of halogen atoms with formation of amino groups bound to carbon atoms of six-membered aromatic rings or from amines having nitrogen atoms bound to carbon atoms of six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C209/00—Preparation of compounds containing amino groups bound to a carbon skeleton
- C07C209/04—Preparation of compounds containing amino groups bound to a carbon skeleton by substitution of functional groups by amino groups
- C07C209/14—Preparation of compounds containing amino groups bound to a carbon skeleton by substitution of functional groups by amino groups by substitution of hydroxy groups or of etherified or esterified hydroxy groups
- C07C209/18—Preparation of compounds containing amino groups bound to a carbon skeleton by substitution of functional groups by amino groups by substitution of hydroxy groups or of etherified or esterified hydroxy groups with formation of amino groups bound to carbon atoms of six-membered aromatic rings or from amines having nitrogen atoms bound to carbon atoms of six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C249/00—Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton
- C07C249/02—Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton of compounds containing imino groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/122,324 US6323366B1 (en) | 1997-07-29 | 1998-07-24 | Arylamine synthesis |
| PCT/US1999/016257 WO2000005199A1 (en) | 1998-07-24 | 1999-07-23 | Improved arylamine synthesis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE258163T1 true ATE258163T1 (de) | 2004-02-15 |
Family
ID=22402053
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT99937293T ATE258163T1 (de) | 1998-07-24 | 1999-07-23 | Verbesserte arylamin-synthese |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US6323366B1 (de) |
| EP (1) | EP1100774B1 (de) |
| JP (1) | JP2002521359A (de) |
| AT (1) | ATE258163T1 (de) |
| CA (1) | CA2336976A1 (de) |
| DE (1) | DE69914337T2 (de) |
| PT (1) | PT1100774E (de) |
| WO (1) | WO2000005199A1 (de) |
Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20050032585A (ko) * | 2002-08-02 | 2005-04-07 | 로디아 파마 솔루션즈 인코포레이티드 | 구리 촉매를 이용한 아릴화 방법 |
| US7138555B2 (en) | 2004-04-20 | 2006-11-21 | Xerox Corporation | Process for preparing iodoaromatic compounds and using the same |
| AU2005272033A1 (en) * | 2004-07-08 | 2006-02-16 | Merck & Co., Inc. | Formation of tetra-substituted enamides and stereoselective reduction thereof |
| US8022053B2 (en) * | 2004-11-02 | 2011-09-20 | Bayer Schering Pharma Aktiengesellschaft | Oral solid dosage forms containing a low dose of estradiol |
| ITMI20050062A1 (it) | 2005-01-20 | 2006-07-21 | Polimeri Europa Spa | Processo per la preparazione di fenolo |
| GT200600207A (es) * | 2005-06-09 | 2007-01-15 | Novartis Ag | Proceso para la síntesis de compuestos orgánicos |
| SA06270147B1 (ar) | 2005-06-09 | 2009-12-22 | نوفارتيس ايه جي | عملية لتخليق 5-(مثيل–1h–إيميدازول–1-يل )–3-(ثلاثي فلـورو مثيل)–بنزامـين |
| JP5567349B2 (ja) | 2007-03-12 | 2014-08-06 | イントラ−セルラー・セラピーズ・インコーポレイテッド | 置換ヘテロ環縮合ガンマ−カルボリンの合成 |
| DE102007039155A1 (de) | 2007-08-16 | 2009-02-19 | Leibnitz-Institut für Katalyse e.V. an der Universität Rostock | Verfahren zur katalytischen Herstellung von N-monoalkylierten Aryl- und Heteroarylaminen |
| NZ605471A (en) | 2010-07-16 | 2015-02-27 | Abbvie Bahamas Ltd | Phosphine ligands for catalytic reactions |
| US8975443B2 (en) | 2010-07-16 | 2015-03-10 | Abbvie Inc. | Phosphine ligands for catalytic reactions |
| AU2011278927B2 (en) | 2010-07-16 | 2015-05-21 | Abbvie Ireland Unlimited Company | Process for preparing antiviral compounds |
| US9255074B2 (en) | 2010-07-16 | 2016-02-09 | Abbvie Inc. | Process for preparing antiviral compounds |
| JP5929298B2 (ja) * | 2011-03-02 | 2016-06-01 | Jnc株式会社 | ジアミン、これを用いた液晶配向剤、液晶表示素子および液晶配向膜の形成方法 |
| ES2727815T3 (es) | 2012-04-14 | 2019-10-18 | Intra Cellular Therapies Inc | Tratamiento del TEPT y de trastornos del control de impulsos |
| EP2968320B1 (de) | 2013-03-15 | 2020-11-11 | Intra-Cellular Therapies, Inc. | Organische verbindungen |
| KR102495941B1 (ko) | 2013-12-03 | 2023-02-06 | 인트라-셀룰라 써래피스, 인코퍼레이티드. | 신규한 방법 |
| MX2016013046A (es) | 2014-04-04 | 2017-02-15 | Intra-Cellular Therapies Inc | Compuestos organicos. |
| BR112016023162B1 (pt) | 2014-04-04 | 2022-11-29 | Intra-Cellular Therapies, Inc | Compostos orgânicos gama-carbolinas, composições farmacêuticas compreendendo os ditos compostos e uso dos mesmos no tratamento ou na profilaxia de transtornos de sistema nervoso central |
| BR112018015283B1 (pt) | 2016-01-26 | 2023-09-26 | Intra-Cellular Therapies, Inc | Compostos orgânicos, composição farmacêutica compreendendo os ditos compostos e uso dos mesmos para o tratamento ou profilaxia de um distúrbio do sistema nervoso central |
| EP3888656A1 (de) | 2016-03-25 | 2021-10-06 | Intra-Cellular Therapies, Inc. | Deuterierte heterozyklische gamma-carboline verbindungen und deren verwendung zur behandlumg oder prophylaxe einer störung des zentralen nervensystems. |
| WO2017172795A1 (en) | 2016-03-28 | 2017-10-05 | Intra-Cellular Therapies, Inc. | Novel compositions and methods |
| EP3436016B1 (de) | 2016-03-28 | 2022-04-27 | Intra-Cellular Therapies, Inc. | Neuartige co-kristalle |
| EP3436455A4 (de) | 2016-03-28 | 2019-09-04 | Intra-Cellular Therapies, Inc. | Neuartige salze und kristalle |
| US11331316B2 (en) | 2016-10-12 | 2022-05-17 | Intra-Cellular Therapies, Inc. | Amorphous solid dispersions |
| US10961245B2 (en) | 2016-12-29 | 2021-03-30 | Intra-Cellular Therapies, Inc. | Substituted heterocycle fused gamma-carbolines for treatment of central nervous system disorders |
| WO2018126143A1 (en) | 2016-12-29 | 2018-07-05 | Intra-Cellular Therapies, Inc. | Organic compounds |
| CA3054841A1 (en) | 2017-03-24 | 2018-09-27 | Intra-Cellular Therapies, Inc. | Novel compositions and methods |
| WO2019023063A1 (en) | 2017-07-26 | 2019-01-31 | Intra-Cellular Therapies, Inc. | ORGANIC COMPOUNDS |
| MX2020000968A (es) | 2017-07-26 | 2020-09-28 | Intra Cellular Therapies Inc | Compuestos organicos. |
| JP7483671B2 (ja) | 2018-06-11 | 2024-05-15 | イントラ－セルラー・セラピーズ・インコーポレイテッド | 置換ヘテロ環縮合ガンマ－カルボリン類合成 |
| EP3843738A4 (de) | 2018-08-31 | 2022-06-01 | Intra-Cellular Therapies, Inc. | Neuartige verfahren |
| WO2020047408A1 (en) | 2018-08-31 | 2020-03-05 | Intra-Cellular Therapies, Inc. | Novel methods |
| WO2021216496A1 (en) * | 2020-04-20 | 2021-10-28 | Tricida, Inc. | Process for the preparation of 1,3-bis(allylamino)propane |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL124467C (de) | 1963-03-27 | |||
| US3657430A (en) * | 1969-06-25 | 1972-04-18 | Merck & Co Inc | Composition and methods for treating inflammation |
| US4096185A (en) | 1976-01-08 | 1978-06-20 | E. I. Du Pont De Nemours And Company | Preparation of p-aminobenzotrifluoride |
| US4204997A (en) | 1979-03-19 | 1980-05-27 | Monsanto Company | Asymmetric amination of 1,3-dienes |
| FR2474491A1 (fr) | 1980-01-30 | 1981-07-31 | Inst Francais Du Petrole | Procede de fabrication d'imines d'aminoacides allyl-substituees convertibles notamment en a-aminoacides |
| US5739396A (en) | 1991-12-09 | 1998-04-14 | Stanford University | Asymmetric ligands useful for transition metal catalyzed bond forming reactions |
| US5919948A (en) | 1991-12-09 | 1999-07-06 | The Board Of Trustees Of The Leland Stanford Junior University | Asymmetric ligands useful for transition metal catalyzed bond forming reactions and epoxide reactions therewith |
| US5576460A (en) | 1994-07-27 | 1996-11-19 | Massachusetts Institute Of Technology | Preparation of arylamines |
| WO1997005151A1 (de) | 1995-07-25 | 1997-02-13 | Clariant Gmbh | Katalysatoren zur durchführung von kreuzkupplungsreaktionen |
| WO1997013763A1 (en) | 1995-10-13 | 1997-04-17 | The Penn State Research Foundation | Asymmetric synthesis catalyzed by transition metal complexes with new chiral ligands |
| JPH09239275A (ja) | 1996-03-10 | 1997-09-16 | Daicel Chem Ind Ltd | イミン化合物合成用触媒、及びこれを用いたイミン化合物の製造法 |
| US5847166A (en) | 1996-10-10 | 1998-12-08 | Massachusetts Institute Of Technology | Synthesis of aryl ethers |
-
1998
- 1998-07-24 US US09/122,324 patent/US6323366B1/en not_active Expired - Lifetime
-
1999
- 1999-07-23 AT AT99937293T patent/ATE258163T1/de not_active IP Right Cessation
- 1999-07-23 EP EP99937293A patent/EP1100774B1/de not_active Expired - Lifetime
- 1999-07-23 PT PT99937293T patent/PT1100774E/pt unknown
- 1999-07-23 JP JP2000561156A patent/JP2002521359A/ja active Pending
- 1999-07-23 CA CA002336976A patent/CA2336976A1/en not_active Abandoned
- 1999-07-23 WO PCT/US1999/016257 patent/WO2000005199A1/en active IP Right Grant
- 1999-07-23 DE DE69914337T patent/DE69914337T2/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| CA2336976A1 (en) | 2000-02-03 |
| DE69914337D1 (de) | 2004-02-26 |
| JP2002521359A (ja) | 2002-07-16 |
| EP1100774B1 (de) | 2004-01-21 |
| DE69914337T2 (de) | 2004-11-04 |
| PT1100774E (pt) | 2004-06-30 |
| EP1100774A1 (de) | 2001-05-23 |
| US6323366B1 (en) | 2001-11-27 |
| WO2000005199A1 (en) | 2000-02-03 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |