ATE256702T1 - Zusammensetzungen und kits zur fluoreszenzpolarisierungsdosierung von grossen molekülen - Google Patents
Zusammensetzungen und kits zur fluoreszenzpolarisierungsdosierung von grossen molekülenInfo
- Publication number
- ATE256702T1 ATE256702T1 AT94922433T AT94922433T ATE256702T1 AT E256702 T1 ATE256702 T1 AT E256702T1 AT 94922433 T AT94922433 T AT 94922433T AT 94922433 T AT94922433 T AT 94922433T AT E256702 T1 ATE256702 T1 AT E256702T1
- Authority
- AT
- Austria
- Prior art keywords
- oligopeptide
- composition
- analyte
- kit
- amino acid
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 6
- 238000002875 fluorescence polarization Methods 0.000 title 1
- 150000002605 large molecules Chemical class 0.000 title 1
- 229920002521 macromolecule Polymers 0.000 title 1
- 102000015636 Oligopeptides Human genes 0.000 abstract 6
- 108010038807 Oligopeptides Proteins 0.000 abstract 6
- 239000012491 analyte Substances 0.000 abstract 4
- 238000000034 method Methods 0.000 abstract 4
- 125000003275 alpha amino acid group Chemical group 0.000 abstract 3
- 238000012216 screening Methods 0.000 abstract 3
- 239000007850 fluorescent dye Substances 0.000 abstract 2
- 238000003556 assay Methods 0.000 abstract 1
- 125000000151 cysteine group Chemical group N[C@@H](CS)C(=O)* 0.000 abstract 1
- 239000000975 dye Substances 0.000 abstract 1
- 238000003018 immunoassay Methods 0.000 abstract 1
- 230000010287 polarization Effects 0.000 abstract 1
- WGTODYJZXSJIAG-UHFFFAOYSA-N tetramethylrhodamine chloride Chemical compound [Cl-].C=12C=CC(N(C)C)=CC2=[O+]C2=CC(N(C)C)=CC=C2C=1C1=CC=CC=C1C(O)=O WGTODYJZXSJIAG-UHFFFAOYSA-N 0.000 abstract 1
- ANRHNWWPFJCPAZ-UHFFFAOYSA-M thionine Chemical compound [Cl-].C1=CC(N)=CC2=[S+]C3=CC(N)=CC=C3N=C21 ANRHNWWPFJCPAZ-UHFFFAOYSA-M 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/59—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g.hCG [human chorionic gonadotropin]; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
- G01N33/542—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Organic Chemistry (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Endocrinology (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Reproductive Health (AREA)
- Toxicology (AREA)
- Genetics & Genomics (AREA)
- Gastroenterology & Hepatology (AREA)
- Cell Biology (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Compositions Of Macromolecular Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Polarising Elements (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US16491193A | 1993-12-09 | 1993-12-09 | |
| PCT/US1994/006166 WO1995015981A1 (en) | 1993-12-09 | 1994-06-01 | Compositions and kits for fluorescence polarization assay of large molecules |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE256702T1 true ATE256702T1 (de) | 2004-01-15 |
Family
ID=22596622
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT94922433T ATE256702T1 (de) | 1993-12-09 | 1994-06-01 | Zusammensetzungen und kits zur fluoreszenzpolarisierungsdosierung von grossen molekülen |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP0733063B1 (de) |
| AT (1) | ATE256702T1 (de) |
| AU (1) | AU7354594A (de) |
| CA (1) | CA2177976C (de) |
| DE (1) | DE69433427T2 (de) |
| WO (1) | WO1995015981A1 (de) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6287774B1 (en) | 1999-05-21 | 2001-09-11 | Caliper Technologies Corp. | Assay methods and system |
| US6472141B2 (en) | 1999-05-21 | 2002-10-29 | Caliper Technologies Corp. | Kinase assays using polycations |
| US6645733B1 (en) | 1999-06-25 | 2003-11-11 | Ingeneus Corporation | Fluorescent intensity method for assaying binding between proteins or peptides |
| DE10245644A1 (de) * | 2002-09-30 | 2004-04-08 | Cibitest Gmbh & Co.Kg. | Verfahren zum Nachweis von Analyten |
| CN102175846A (zh) * | 2010-12-24 | 2011-09-07 | 江南大学 | 一种双酚a的荧光偏振免疫分析检测方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL63224A (en) * | 1980-07-17 | 1985-05-31 | Scripps Clinic Res | Synthetic peptide specific antigenic determinant and method of manufacturing antigenic materials therefrom |
| US4681859A (en) * | 1984-09-21 | 1987-07-21 | Ortho Diagnostic Systems Inc. | Fluorescence polarization immunoassay for heavy antigens |
| US5075211A (en) * | 1986-03-26 | 1991-12-24 | Genetic Systems Corporation | Synthetic antigen for the detection of AIDS-related disease |
| DE3806430A1 (de) * | 1988-02-29 | 1989-09-07 | Boehringer Mannheim Gmbh | Verfahren zur bestimmung eines proteins nach dem prinzip des fluoreszenz-polarisations-immunoassays |
| DE3833936C1 (de) * | 1988-10-05 | 1989-09-21 | Henning Berlin Gmbh Chemie- Und Pharmawerk, 1000 Berlin, De |
-
1994
- 1994-06-01 AT AT94922433T patent/ATE256702T1/de not_active IP Right Cessation
- 1994-06-01 CA CA002177976A patent/CA2177976C/en not_active Expired - Fee Related
- 1994-06-01 EP EP94922433A patent/EP0733063B1/de not_active Expired - Lifetime
- 1994-06-01 WO PCT/US1994/006166 patent/WO1995015981A1/en active IP Right Grant
- 1994-06-01 AU AU73545/94A patent/AU7354594A/en not_active Abandoned
- 1994-06-01 DE DE69433427T patent/DE69433427T2/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| AU7354594A (en) | 1995-06-27 |
| CA2177976C (en) | 2007-12-04 |
| WO1995015981A1 (en) | 1995-06-15 |
| CA2177976A1 (en) | 1995-06-15 |
| DE69433427D1 (de) | 2004-01-29 |
| EP0733063B1 (de) | 2003-12-17 |
| DE69433427T2 (de) | 2004-09-16 |
| EP0733063A4 (de) | 2001-12-05 |
| EP0733063A1 (de) | 1996-09-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |