ATE128233T1 - Zellnekrosnachweis durch prüfung von spektrin und seine abbauprodukte. - Google Patents

Zellnekrosnachweis durch prüfung von spektrin und seine abbauprodukte.

Info

Publication number
ATE128233T1
ATE128233T1 AT91913322T AT91913322T ATE128233T1 AT E128233 T1 ATE128233 T1 AT E128233T1 AT 91913322 T AT91913322 T AT 91913322T AT 91913322 T AT91913322 T AT 91913322T AT E128233 T1 ATE128233 T1 AT E128233T1
Authority
AT
Austria
Prior art keywords
spectrin
bdp
detection
necros
testing
Prior art date
Application number
AT91913322T
Other languages
English (en)
Inventor
Gary S Lynch
David D Eveleth Jr
Peter A Seubert
Original Assignee
Univ California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ California filed Critical Univ California
Application granted granted Critical
Publication of ATE128233T1 publication Critical patent/ATE128233T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/558—Immunoassay; Biospecific binding assay; Materials therefor using diffusion or migration of antigen or antibody
    • G01N33/561—Immunoelectrophoresis
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/811—Test for named disease, body condition or organ function
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
AT91913322T 1990-07-26 1991-07-11 Zellnekrosnachweis durch prüfung von spektrin und seine abbauprodukte. ATE128233T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/558,700 US5118606A (en) 1988-09-02 1990-07-26 Methods for detecting cellular pathology by assaying spectrin and spectrin breakdown products

Publications (1)

Publication Number Publication Date
ATE128233T1 true ATE128233T1 (de) 1995-10-15

Family

ID=24230602

Family Applications (1)

Application Number Title Priority Date Filing Date
AT91913322T ATE128233T1 (de) 1990-07-26 1991-07-11 Zellnekrosnachweis durch prüfung von spektrin und seine abbauprodukte.

Country Status (10)

Country Link
US (1) US5118606A (de)
EP (1) EP0540591B1 (de)
JP (2) JP2824150B2 (de)
AT (1) ATE128233T1 (de)
CA (1) CA2088050A1 (de)
DE (1) DE69113273T2 (de)
DK (1) DK0540591T3 (de)
ES (1) ES2077863T3 (de)
GR (1) GR3017459T3 (de)
WO (1) WO1992001935A1 (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5444042A (en) * 1990-12-28 1995-08-22 Cortex Pharmaceuticals Method of treatment of neurodegeneration with calpain inhibitors
US5536639A (en) * 1994-03-25 1996-07-16 Cephalon, Inc. Methods for detecting calpain activation by detection of calpain activated spectrin breakdown products
CA2188816C (en) * 1996-04-23 2009-09-22 Takeda Chemical Industries, Ltd. Composition containing .alpha.-fodrin or .alpha.- fodrin fragment protein
US6011991A (en) * 1998-12-07 2000-01-04 Technology Patents, Llc Communication system and method including brain wave analysis and/or use of brain activity
WO2004025298A1 (en) * 2002-09-11 2004-03-25 University Of Florida Analyzing nerve cell damage
ES2367311T3 (es) * 2004-04-15 2011-11-02 University Of Florida Research Foundation, Inc. Productos de degradación proteolítica de map-2 como biomarcadores de diagnóstico para las lesiones neurales.
US8492107B2 (en) 2004-04-15 2013-07-23 University Of Florida Research Foundation, Inc. Neural proteins as biomarkers for nervous system injury and other neural disorders
EP2207033B1 (de) * 2004-04-15 2014-06-18 University of Florida Research Foundation, Inc. Neuralproteine als Biomarker für Verletzungen des Nervensystems und anderen neuralen Störungen
WO2008097618A1 (en) * 2007-02-06 2008-08-14 University Of Florida Research Foundation, Inc. Synaptotagmin and collapsin response mediator protein as biomarkers for traumatic brain injury
WO2009026660A1 (en) 2007-08-30 2009-03-05 Walter And Eliza Hall Institute Of Medical Research Dendritic cell marker and uses thereof
EP2424560A4 (de) * 2009-03-23 2013-11-27 Inst Medical W & E Hall Verbindungen und verfahren zur modulation der immunreaktion
US20120196935A1 (en) * 2009-09-18 2012-08-02 The Regents Of The University Of California Methods for detecting autodigestion
CA2813467A1 (en) 2010-10-02 2012-04-05 The Regents Of The University Of California Minimizing intestinal dysfunction
WO2012170669A1 (en) * 2011-06-07 2012-12-13 Yale University Avenue Biomarkers for assessment of the molecular quality in biospecimens
EP3684463A4 (de) 2017-09-19 2021-06-23 Neuroenhancement Lab, LLC Verfahren und vorrichtung für neuro-enhancement
US11717686B2 (en) 2017-12-04 2023-08-08 Neuroenhancement Lab, LLC Method and apparatus for neuroenhancement to facilitate learning and performance
WO2019133997A1 (en) 2017-12-31 2019-07-04 Neuroenhancement Lab, LLC System and method for neuroenhancement to enhance emotional response
US11364361B2 (en) 2018-04-20 2022-06-21 Neuroenhancement Lab, LLC System and method for inducing sleep by transplanting mental states
CN113382683A (zh) 2018-09-14 2021-09-10 纽罗因恒思蒙特实验有限责任公司 改善睡眠的系统和方法
US11786694B2 (en) 2019-05-24 2023-10-17 NeuroLight, Inc. Device, method, and app for facilitating sleep
EP4065986A4 (de) * 2019-11-26 2023-11-15 Ohio State Innovation Foundation Verfahren und zusammensetzungen zur erkennung und zum management von kardiovaskulären erkrankungen

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE68923285T2 (de) * 1988-09-02 1995-11-09 Univ California Verfahren zum nachweis der zellularer pathologie.

Also Published As

Publication number Publication date
JPH05508919A (ja) 1993-12-09
EP0540591B1 (de) 1995-09-20
GR3017459T3 (en) 1995-12-31
DK0540591T3 (da) 1996-02-05
DE69113273T2 (de) 1996-05-15
US5118606A (en) 1992-06-02
ES2077863T3 (es) 1995-12-01
WO1992001935A1 (en) 1992-02-06
JPH1130615A (ja) 1999-02-02
JP2824150B2 (ja) 1998-11-11
DE69113273D1 (de) 1995-10-26
CA2088050A1 (en) 1992-01-27
EP0540591A1 (de) 1993-05-12

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