ATE25521T1 - 5-(amino oder substituierte amino)-imidazole. - Google Patents

5-(amino oder substituierte amino)-imidazole.

Info

Publication number
ATE25521T1
ATE25521T1 AT83307692T AT83307692T ATE25521T1 AT E25521 T1 ATE25521 T1 AT E25521T1 AT 83307692 T AT83307692 T AT 83307692T AT 83307692 T AT83307692 T AT 83307692T AT E25521 T1 ATE25521 T1 AT E25521T1
Authority
AT
Austria
Prior art keywords
amino
alkyl
substituted
acetamido
chem
Prior art date
Application number
AT83307692T
Other languages
English (en)
Inventor
John C Chabala
Michael H Fisher
Arthur A Patchett
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Application granted granted Critical
Publication of ATE25521T1 publication Critical patent/ATE25521T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/02Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/90Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Emulsifying, Dispersing, Foam-Producing Or Wetting Agents (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
AT83307692T 1982-12-20 1983-12-16 5-(amino oder substituierte amino)-imidazole. ATE25521T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US45084882A 1982-12-20 1982-12-20
EP83307692A EP0113570B1 (de) 1982-12-20 1983-12-16 5-(Amino oder substituierte Amino)-Imidazole

Publications (1)

Publication Number Publication Date
ATE25521T1 true ATE25521T1 (de) 1987-03-15

Family

ID=23789738

Family Applications (1)

Application Number Title Priority Date Filing Date
AT83307692T ATE25521T1 (de) 1982-12-20 1983-12-16 5-(amino oder substituierte amino)-imidazole.

Country Status (8)

Country Link
EP (1) EP0113570B1 (de)
JP (1) JPS59118772A (de)
AT (1) ATE25521T1 (de)
CA (1) CA1245660A (de)
DE (1) DE3369845D1 (de)
DK (1) DK584283A (de)
ES (1) ES528159A0 (de)
IE (1) IE56381B1 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59167515A (ja) * 1983-03-15 1984-09-21 Ajinomoto Co Inc 免疫機能増強剤
EP0151528B1 (de) * 1984-02-02 1990-07-04 Merck & Co. Inc. 5-(Amino oder substituiertes Amino)-1,2,3-Triazole
DE3627155A1 (de) * 1986-08-11 1988-02-18 Schering Ag Imidazol-derivate
FI91754C (fi) * 1986-12-02 1994-08-10 Tanabe Seiyaku Co Analogiamenetelmä lääkeaineena käyttökelpoisen imidatsolijohdannaisen valmistamiseksi
CA1329614C (en) * 1987-05-02 1994-05-17 Rainer Buerstinghaus N-substituted azoles
US5359078A (en) * 1989-05-19 1994-10-25 The United States Of America As Represented By The Department Of Health And Human Services Signal transduction inhibitor compounds
US5635521A (en) * 1991-09-23 1997-06-03 Sandoz Ltd. Imidazolylmethyl-pyridines
KR100401283B1 (ko) * 1998-07-13 2003-12-31 주식회사유한양행 라스변이세포성장억제구아니딘유도체
MXPA03006402A (es) * 2001-01-18 2003-10-15 Schering Corp Sintesis de temozolomida y analogos.
MXPA03006403A (es) 2001-01-18 2003-10-15 Schering Corp Sintesis de la temozolomida y analogos.

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4265900A (en) * 1979-10-29 1981-05-05 Mcneilab, Inc. N-Aryl-N'-imidazol-2-ylureas
JPS5671074A (en) * 1979-11-12 1981-06-13 Takeda Chem Ind Ltd 1,2-disubstituted-4-halogenoimidazole-5-acetic acid derivative

Also Published As

Publication number Publication date
EP0113570B1 (de) 1987-02-25
IE56381B1 (en) 1991-07-17
DK584283A (da) 1984-06-21
JPS59118772A (ja) 1984-07-09
DK584283D0 (da) 1983-12-19
ES8505202A1 (es) 1985-05-16
DE3369845D1 (en) 1987-04-02
ES528159A0 (es) 1985-05-16
CA1245660A (en) 1988-11-29
IE832975L (en) 1984-06-20
EP0113570A1 (de) 1984-07-18

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee