ATE253366T1 - Verwendung von 7-apha-methyl-17-alpha-ethynyl- estrane derivaten zur behandlung von atherosclerose - Google Patents

Verwendung von 7-apha-methyl-17-alpha-ethynyl- estrane derivaten zur behandlung von atherosclerose

Info

Publication number
ATE253366T1
ATE253366T1 AT98912450T AT98912450T ATE253366T1 AT E253366 T1 ATE253366 T1 AT E253366T1 AT 98912450 T AT98912450 T AT 98912450T AT 98912450 T AT98912450 T AT 98912450T AT E253366 T1 ATE253366 T1 AT E253366T1
Authority
AT
Austria
Prior art keywords
apha
ethynyl
atherosclerosis
alpha
methyl
Prior art date
Application number
AT98912450T
Other languages
English (en)
Inventor
Dirk Gerrit Meuleman
Pieter Zandberg
Original Assignee
Akzo Nobel Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo Nobel Nv filed Critical Akzo Nobel Nv
Application granted granted Critical
Publication of ATE253366T1 publication Critical patent/ATE253366T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/567Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in position 17 alpha, e.g. mestranol, norethandrolone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT98912450T 1997-03-05 1998-03-03 Verwendung von 7-apha-methyl-17-alpha-ethynyl- estrane derivaten zur behandlung von atherosclerose ATE253366T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP97200646 1997-03-05
PCT/EP1998/001293 WO1998039012A1 (en) 1997-03-05 1998-03-03 USE OF A 7α-METHYL-17α-ETHYNYL-ESTRANE DERIVATIVE FOR THE TREATMENT OF ATHEROSCLEROSIS

Publications (1)

Publication Number Publication Date
ATE253366T1 true ATE253366T1 (de) 2003-11-15

Family

ID=8228079

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98912450T ATE253366T1 (de) 1997-03-05 1998-03-03 Verwendung von 7-apha-methyl-17-alpha-ethynyl- estrane derivaten zur behandlung von atherosclerose

Country Status (21)

Country Link
EP (1) EP0994713B1 (de)
JP (1) JP2001515478A (de)
KR (1) KR100556558B1 (de)
CN (1) CN1159014C (de)
AR (1) AR015371A1 (de)
AT (1) ATE253366T1 (de)
AU (1) AU733758B2 (de)
BR (1) BR9808194A (de)
CA (1) CA2283418A1 (de)
DE (1) DE69819503T2 (de)
DK (1) DK0994713T3 (de)
ES (1) ES2210731T3 (de)
HK (1) HK1025510A1 (de)
HU (1) HUP0001499A3 (de)
IL (1) IL123422A (de)
NO (1) NO994305L (de)
PL (1) PL335904A1 (de)
TR (1) TR199902510T2 (de)
TW (1) TW448049B (de)
WO (1) WO1998039012A1 (de)
ZA (1) ZA981731B (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19834931A1 (de) * 1998-07-28 2000-02-24 Jenapharm Gmbh Verwendung von biogenen Estrogenen zur Hormonsubstitutionstherapie
CN100432093C (zh) 1998-10-16 2008-11-12 欧加农股份有限公司 包含(7α,17α)-17-羟基-7-甲基-19-去甲-17-孕-5(10)-烯-20-炔-3-酮的高纯度组合物

Also Published As

Publication number Publication date
KR100556558B1 (ko) 2006-03-06
TW448049B (en) 2001-08-01
ES2210731T3 (es) 2004-07-01
WO1998039012A1 (en) 1998-09-11
CN1252723A (zh) 2000-05-10
AU733758B2 (en) 2001-05-24
AU6728498A (en) 1998-09-22
DK0994713T3 (da) 2004-03-08
KR20000075966A (ko) 2000-12-26
DE69819503D1 (de) 2003-12-11
DE69819503T2 (de) 2004-09-23
IL123422A (en) 2003-05-29
AR015371A1 (es) 2001-05-02
HUP0001499A2 (hu) 2000-11-28
JP2001515478A (ja) 2001-09-18
NO994305D0 (no) 1999-09-03
CA2283418A1 (en) 1998-09-11
ZA981731B (en) 1998-09-07
IL123422A0 (en) 1998-09-24
TR199902510T2 (xx) 2000-02-21
NO994305L (no) 1999-11-01
PL335904A1 (en) 2000-05-22
BR9808194A (pt) 2000-05-16
HK1025510A1 (en) 2000-11-17
EP0994713A1 (de) 2000-04-26
HUP0001499A3 (en) 2001-03-28
CN1159014C (zh) 2004-07-28
EP0994713B1 (de) 2003-11-05

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Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties