ATE252557T1 - Verfahren zur herstellung eines indolderivates - Google Patents
Verfahren zur herstellung eines indolderivatesInfo
- Publication number
- ATE252557T1 ATE252557T1 AT99938234T AT99938234T ATE252557T1 AT E252557 T1 ATE252557 T1 AT E252557T1 AT 99938234 T AT99938234 T AT 99938234T AT 99938234 T AT99938234 T AT 99938234T AT E252557 T1 ATE252557 T1 AT E252557T1
- Authority
- AT
- Austria
- Prior art keywords
- producing
- indole derivative
- indole
- carboxylate
- chloropropanol
- Prior art date
Links
- SIKJAQJRHWYJAI-UHFFFAOYSA-N Indole Chemical class C1=CC=C2NC=CC2=C1 SIKJAQJRHWYJAI-UHFFFAOYSA-N 0.000 title abstract 2
- 238000004519 manufacturing process Methods 0.000 title 1
- LAMUXTNQCICZQX-UHFFFAOYSA-N 3-chloropropan-1-ol Chemical compound OCCCCl LAMUXTNQCICZQX-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- PZOUSPYUWWUPPK-UHFFFAOYSA-N indole Natural products CC1=CC=CC2=C1C=CN2 PZOUSPYUWWUPPK-UHFFFAOYSA-N 0.000 abstract 1
- RKJUIXBNRJVNHR-UHFFFAOYSA-N indolenine Natural products C1=CC=C2CC=NC2=C1 RKJUIXBNRJVNHR-UHFFFAOYSA-N 0.000 abstract 1
- IJQYPUZBTYDSGN-UHFFFAOYSA-N methyl 2-(3-chloropropoxy)-1h-indole-3-carboxylate Chemical compound C1=CC=C2C(C(=O)OC)=C(OCCCCl)NC2=C1 IJQYPUZBTYDSGN-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Indole Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9815481.8A GB9815481D0 (en) | 1998-07-16 | 1998-07-16 | Pharmaceuticals |
| PCT/EP1999/004944 WO2000003984A1 (en) | 1998-07-16 | 1999-07-13 | Process for the preparation of an indole derivate |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE252557T1 true ATE252557T1 (de) | 2003-11-15 |
Family
ID=10835640
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT99938234T ATE252557T1 (de) | 1998-07-16 | 1999-07-13 | Verfahren zur herstellung eines indolderivates |
Country Status (8)
| Country | Link |
|---|---|
| EP (1) | EP1097136B1 (https=) |
| JP (1) | JP3842556B2 (https=) |
| AT (1) | ATE252557T1 (https=) |
| CA (1) | CA2337382C (https=) |
| DE (1) | DE69912282T2 (https=) |
| ES (1) | ES2209476T3 (https=) |
| GB (1) | GB9815481D0 (https=) |
| WO (1) | WO2000003984A1 (https=) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0211230D0 (en) | 2002-05-16 | 2002-06-26 | Medinnova Sf | Treatment of heart failure |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3911297B2 (ja) * | 1996-08-16 | 2007-05-09 | スミスクライン・ビーチャム・パブリック・リミテッド・カンパニー | Ｎ―［（１―ｎブチル―４―ピペリジル）メチル］―３，４―ジヒドロ―２Ｈ―［１，３］オキサジノ［３，２―ａ］インドール―１０―カルボキシアミドおよび塩ならびに製造における中間体 |
-
1998
- 1998-07-16 GB GBGB9815481.8A patent/GB9815481D0/en not_active Ceased
-
1999
- 1999-07-13 JP JP2000560093A patent/JP3842556B2/ja not_active Expired - Fee Related
- 1999-07-13 WO PCT/EP1999/004944 patent/WO2000003984A1/en not_active Ceased
- 1999-07-13 CA CA002337382A patent/CA2337382C/en not_active Expired - Fee Related
- 1999-07-13 DE DE69912282T patent/DE69912282T2/de not_active Expired - Lifetime
- 1999-07-13 AT AT99938234T patent/ATE252557T1/de not_active IP Right Cessation
- 1999-07-13 ES ES99938234T patent/ES2209476T3/es not_active Expired - Lifetime
- 1999-07-13 EP EP99938234A patent/EP1097136B1/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| ES2209476T3 (es) | 2004-06-16 |
| DE69912282T2 (de) | 2004-07-29 |
| EP1097136A1 (en) | 2001-05-09 |
| WO2000003984A1 (en) | 2000-01-27 |
| GB9815481D0 (en) | 1998-09-16 |
| JP2002520392A (ja) | 2002-07-09 |
| EP1097136B1 (en) | 2003-10-22 |
| CA2337382A1 (en) | 2000-01-27 |
| DE69912282D1 (de) | 2003-11-27 |
| CA2337382C (en) | 2008-04-08 |
| JP3842556B2 (ja) | 2006-11-08 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |