ATE251220T1 - Verfahen zur gleichzeitigen identifikation von differentielle exprimierten mrna's und zur messung ihrer relativen konzentration - Google Patents

Verfahen zur gleichzeitigen identifikation von differentielle exprimierten mrna's und zur messung ihrer relativen konzentration

Info

Publication number
ATE251220T1
ATE251220T1 AT95901229T AT95901229T ATE251220T1 AT E251220 T1 ATE251220 T1 AT E251220T1 AT 95901229 T AT95901229 T AT 95901229T AT 95901229 T AT95901229 T AT 95901229T AT E251220 T1 ATE251220 T1 AT E251220T1
Authority
AT
Austria
Prior art keywords
cdna
mrna
primers
crna
derived
Prior art date
Application number
AT95901229T
Other languages
English (en)
Inventor
Mark G Erlander
Gregor J Sutcliffe
Original Assignee
Scripps Research Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scripps Research Inst filed Critical Scripps Research Inst
Application granted granted Critical
Publication of ATE251220T1 publication Critical patent/ATE251220T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/10Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1096Processes for the isolation, preparation or purification of DNA or RNA cDNA Synthesis; Subtracted cDNA library construction, e.g. RT, RT-PCR
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6809Methods for determination or identification of nucleic acids involving differential detection
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844Nucleic acid amplification reactions
    • C12Q1/6853Nucleic acid amplification reactions using modified primers or templates
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/158Expression markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Plant Pathology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
AT95901229T 1993-11-12 1994-11-14 Verfahen zur gleichzeitigen identifikation von differentielle exprimierten mrna's und zur messung ihrer relativen konzentration ATE251220T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/152,482 US5459037A (en) 1993-11-12 1993-11-12 Method for simultaneous identification of differentially expressed mRNAs and measurement of relative concentrations
PCT/US1994/013041 WO1995013369A1 (en) 1993-11-12 1994-11-14 METHOD FOR SIMULTANEOUS IDENTIFICATION OF DIFFERENTIALLY EXPRESSED mRNAs AND MEASUREMENT OF RELATIVE CONCENTRATIONS

Publications (1)

Publication Number Publication Date
ATE251220T1 true ATE251220T1 (de) 2003-10-15

Family

ID=22543116

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95901229T ATE251220T1 (de) 1993-11-12 1994-11-14 Verfahen zur gleichzeitigen identifikation von differentielle exprimierten mrna's und zur messung ihrer relativen konzentration

Country Status (9)

Country Link
US (6) US5459037A (de)
EP (1) EP0726946B1 (de)
JP (1) JPH09509306A (de)
AT (1) ATE251220T1 (de)
CA (1) CA2174966A1 (de)
DE (1) DE69433210D1 (de)
FI (1) FI962000A0 (de)
NO (1) NO961902L (de)
WO (1) WO1995013369A1 (de)

Families Citing this family (91)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7049102B1 (en) 1989-09-22 2006-05-23 Board Of Trustees Of Leland Stanford University Multi-gene expression profile
US5545522A (en) 1989-09-22 1996-08-13 Van Gelder; Russell N. Process for amplifying a target polynucleotide sequence using a single primer-promoter complex
US5459037A (en) * 1993-11-12 1995-10-17 The Scripps Research Institute Method for simultaneous identification of differentially expressed mRNAs and measurement of relative concentrations
US6096503A (en) * 1993-11-12 2000-08-01 The Scripps Research Institute Method for simultaneous identification of differentially expresses mRNAs and measurement of relative concentrations
US6110680A (en) * 1993-11-12 2000-08-29 The Scripps Research Institute Method for simultaneous identification of differentially expressed mRNAs and measurement of relative concentrations
RU2111254C1 (ru) * 1994-07-11 1998-05-20 Институт молекулярной биологии им.В.А.Энгельгардта РАН СПОСОБ ДЕТЕКЦИИ ДИФФЕРЕНЦИАЛЬНО ЭКСПРЕССИРУЮЩИХСЯ МАТРИЧНЫХ РНК И КЛОНИРОВАНИЯ СООТВЕТСТВУЮЩИХ ИМ ФРАГМЕНТОВ кДНК
IT1275909B1 (it) * 1995-03-07 1997-10-24 Mirella Pilone Frammento di dna codificante d-amminoacido ossidasi
US5707807A (en) * 1995-03-28 1998-01-13 Research Development Corporation Of Japan Molecular indexing for expressed gene analysis
US5712126A (en) * 1995-08-01 1998-01-27 Yale University Analysis of gene expression by display of 3-end restriction fragments of CDNA
US6395887B1 (en) 1995-08-01 2002-05-28 Yale University Analysis of gene expression by display of 3'-end fragments of CDNAS
US5866330A (en) * 1995-09-12 1999-02-02 The Johns Hopkins University School Of Medicine Method for serial analysis of gene expression
US6418382B2 (en) 1995-10-24 2002-07-09 Curagen Corporation Method and apparatus for identifying, classifying, or quantifying DNA sequences in a sample without sequencing
US5871697A (en) 1995-10-24 1999-02-16 Curagen Corporation Method and apparatus for identifying, classifying, or quantifying DNA sequences in a sample without sequencing
US5972693A (en) * 1995-10-24 1999-10-26 Curagen Corporation Apparatus for identifying, classifying, or quantifying DNA sequences in a sample without sequencing
WO1997029211A1 (en) 1996-02-09 1997-08-14 The Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services RESTRICTION DISPLAY (RD-PCR) OF DIFFERENTIALLY EXPRESSED mRNAs
US5824662A (en) * 1996-09-27 1998-10-20 Guilford Pharmaceuticals Inc. Treatment of global and focal ischemia using naaladase inhibitors
US6017903A (en) 1996-09-27 2000-01-25 Guilford Pharmaceuticals Inc. Pharmaceutical compositions and methods of treating a glutamate abnormality and effecting a neuronal activity in an animal using NAALADase inhibitors
AU4174397A (en) 1996-08-30 1998-03-19 Life Technologies, Inc. Methods for identification and isolation of specific nucleotide sequences in cdna and genomic dna
HUP0001062A3 (en) 1996-09-27 2001-09-28 Guilford Pharmaceuticals Inc B Pharmaceutical compositions of phosphinic acid derivatives having naaladase inhibitor acivity
US6013437A (en) * 1996-11-12 2000-01-11 Qbi Enterprises, Ltd. Method for identifying translationally regulated genes
WO1998021321A1 (en) * 1996-11-12 1998-05-22 Qbi Enterprises Ltd. Method for identifying translationally regulated genes
AU722819B2 (en) * 1996-12-06 2000-08-10 Urocor, Inc. Diagnosis of disease state using mRNA profiles
US6461814B1 (en) 1997-01-15 2002-10-08 Dominic G. Spinella Method of identifying gene transcription patterns
US5968784A (en) * 1997-01-15 1999-10-19 Chugai Pharmaceutical Co., Ltd. Method for analyzing quantitative expression of genes
US6306588B1 (en) 1997-02-07 2001-10-23 Invitrogen Corporation Polymerases for analyzing or typing polymorphic nucleic acid fragments and uses thereof
US6190857B1 (en) 1997-03-24 2001-02-20 Urocor, Inc. Diagnosis of disease state using MRNA profiles in peripheral leukocytes
US7332270B1 (en) 1997-03-24 2008-02-19 Urocor, Inc. Diagnosis of disease state using mRNA profiles in peripheral leukocytes
US5958688A (en) * 1997-04-28 1999-09-28 The Trustees Of The University Of Pennsylvania Characterization of mRNA patterns in neurites and single cells for medical diagnosis and therapeutics
WO1998049345A1 (en) * 1997-04-29 1998-11-05 Trustees Of Boston University Methods and compositions for targeted dna differential display
US6261770B1 (en) 1997-05-13 2001-07-17 Display Systems Biotech Aps Method to clone mRNAs
ATE205879T1 (de) * 1997-05-13 2001-10-15 Azign Bioscience As Eine methode zum klonieren von mrna und darstellung von differentiell exprimierten transcripten (dodet)
US6373971B1 (en) * 1997-06-12 2002-04-16 International Business Machines Corporation Method and apparatus for pattern discovery in protein sequences
US6190868B1 (en) 1997-08-07 2001-02-20 Curagen Corporation Method for identifying a nucleic acid sequence
WO1999028505A1 (en) * 1997-12-03 1999-06-10 Curagen Corporation Methods and devices for measuring differential gene expression
US6265546B1 (en) 1997-12-22 2001-07-24 Genset Prostate cancer gene
US5945522A (en) * 1997-12-22 1999-08-31 Genset Prostate cancer gene
DK1052292T3 (da) 1997-12-22 2003-07-28 Genset Sa Prostatacancer-gen
US7189833B2 (en) * 1997-12-22 2007-03-13 Serono Genetics Institute S.A. Prostate cancer gene
US5972615A (en) * 1998-01-21 1999-10-26 Urocor, Inc. Biomarkers and targets for diagnosis, prognosis and management of prostate disease
DE19806431C1 (de) 1998-02-17 1999-10-14 Novartis Ag Neues Verfahren zur Identifikation und Charakterisierung von mRNA-Molekülen
AU3981799A (en) * 1998-05-11 1999-11-29 Quark Biotech, Inc. Method for identifying genes
DE19822287C2 (de) * 1998-05-18 2003-04-24 Switch Biotech Ag Klonierungsvektor, seine Herstellung und Verwendung zur Analyse von mRNA Expressionsmuster
WO2000018966A2 (en) * 1998-09-29 2000-04-06 Arch Development Corporation A new strategy for genome-wide gene analysis: integrated procedures for gene identification
US20020012922A1 (en) * 1998-11-04 2002-01-31 Hilbush Brian S. Simplified method for indexing and determining the relative concentration of expressed messenger RNAs
KR20010092721A (ko) * 1998-11-04 2001-10-26 추후제출 발현된 메신저 rna의 상대적인 농도를 산출하고 결정하는방법
WO2000028090A2 (en) 1998-11-12 2000-05-18 Nyxis, Inc. Diagnostic assay for cancer
US6750012B1 (en) * 1998-12-21 2004-06-15 Curagen Corporation Method of identifying a psychotropic agent using differential gene expression
US6429302B1 (en) 1999-02-02 2002-08-06 Chiron Corporation Polynucleotides related to pancreatic disease
US20060234246A1 (en) * 1999-02-02 2006-10-19 Chiron Corporation Gene products differentially expressed in cancerous cells
WO2000061738A2 (en) * 1999-04-12 2000-10-19 Digital Gene Technologies, Inc. Differential regulation of gene expression in oncogenic transformation
WO2000068423A2 (en) * 1999-05-05 2000-11-16 The European Molecular Biology Laboratory Improved predictive power of rna analysis for protein expression
US6334099B1 (en) 1999-05-25 2001-12-25 Digital Gene Technologies, Inc. Methods for normalization of experimental data
US7838225B2 (en) * 1999-10-29 2010-11-23 Hologic, Inc. Methods for detection of a target nucleic acid by forming a cleavage structure using a reverse transcriptase
AU1466001A (en) * 1999-11-05 2001-05-14 Phase-1 Molecular Toxicology Methods of determining individual hypersensitivity to an agent
EP1255860A2 (de) 1999-12-29 2002-11-13 Mergen Ltd. Festphasen multiplex amplifizierung von polynukleotiden
JP2004524801A (ja) * 2000-04-12 2004-08-19 ザ クリーブランド クリニック ファウンデーション Are含有遺伝子の発現を同定および分析するための方法
US6387624B1 (en) 2000-04-14 2002-05-14 Incyte Pharmaceuticals, Inc. Construction of uni-directionally cloned cDNA libraries from messenger RNA for improved 3′ end DNA sequencing
AU2001268449A1 (en) 2000-06-14 2001-12-24 Vistagen, Inc. Toxicity typing using liver stem cells
WO2002002805A2 (en) * 2000-06-30 2002-01-10 Syngenta Participations Ag Method for identification, separation and quantitative measurement of nucleic acid fragments
US7300751B2 (en) * 2000-06-30 2007-11-27 Syngenta Participations Ag Method for identification of genetic markers
US20040166499A1 (en) * 2000-10-05 2004-08-26 Yoshihide Hayashizaki Oligonucleotide linkers comprising a variable cohesive portion and method for the praparation of polynucleotide libraries by using said linkers
US6391592B1 (en) * 2000-12-14 2002-05-21 Affymetrix, Inc. Blocker-aided target amplification of nucleic acids
WO2002059359A2 (en) 2001-01-24 2002-08-01 Syngenta Participations Ag Method for non-redundant library construction
US20030165865A1 (en) * 2001-01-29 2003-09-04 Hinkel Christopher A. Methods of analysis of nucleic acids
DE10114063A1 (de) * 2001-03-22 2002-10-10 Mpb Cologne Gmbh Molecular Pla Neue Pflanzengene und deren Verwendung zur Isolierung von konstitutiven oder induzierbaren Promotoren
US7419958B2 (en) 2001-03-26 2008-09-02 Dana-Farber Cancer Institute, Inc. Method of attenuating reactions to skin irritants
US6949340B2 (en) 2001-03-28 2005-09-27 Creative Mines Llc Optical phase modulator
US7026121B1 (en) 2001-06-08 2006-04-11 Expression Diagnostics, Inc. Methods and compositions for diagnosing and monitoring transplant rejection
US6905827B2 (en) 2001-06-08 2005-06-14 Expression Diagnostics, Inc. Methods and compositions for diagnosing or monitoring auto immune and chronic inflammatory diseases
US7235358B2 (en) 2001-06-08 2007-06-26 Expression Diagnostics, Inc. Methods and compositions for diagnosing and monitoring transplant rejection
CN101974480A (zh) 2001-06-22 2011-02-16 干细胞股份有限公司 肝移植细胞、测定及其应用
US20030170695A1 (en) * 2001-06-29 2003-09-11 Liang Shi Enzymatic ligation-based identification of nucleotide sequences
US20030082584A1 (en) * 2001-06-29 2003-05-01 Liang Shi Enzymatic ligation-based identification of transcript expression
WO2003010516A1 (en) * 2001-07-23 2003-02-06 Curagen Corporation Method for identifying a nucleic acid sequence
DE10143106C1 (de) * 2001-09-03 2002-10-10 Artus Ges Fuer Molekularbiolog Vermehrung von Ribonukleinsäuren
US20120077196A9 (en) * 2001-09-03 2012-03-29 Guido Krupp Universal method for selective amplification of mRNAs
DE10240868A1 (de) * 2002-09-04 2004-03-18 Artus Gesellschaft für molekularbiologische Diagnostik und Entwicklung mbH Verbesserte Verfahren zur Synthese von Nukleinsäuren
US20050003369A1 (en) * 2002-10-10 2005-01-06 Affymetrix, Inc. Method for depleting specific nucleic acids from a mixture
US7892745B2 (en) 2003-04-24 2011-02-22 Xdx, Inc. Methods and compositions for diagnosing and monitoring transplant rejection
US20050042660A1 (en) * 2003-07-31 2005-02-24 Hall Gerald Edward Devices and methods for isolating RNA
US20050026175A1 (en) * 2003-07-31 2005-02-03 John Link Devices and methods for isolating RNA
US20060099605A1 (en) * 2004-11-11 2006-05-11 Hall Gerald E Jr Devices and methods for isolating RNA
US7645575B2 (en) 2004-09-08 2010-01-12 Xdx, Inc. Genes useful for diagnosing and monitoring inflammation related disorders
US20080241174A1 (en) * 2005-03-18 2008-10-02 The Board Of Trustees Of The Leland Stanford Junior University Production And Therapeutic Uses Of Th1-Like Regulatory T Cells
US20060270843A1 (en) * 2005-05-26 2006-11-30 Hall Gerald E Jr Methods for isolation of nucleic acids
US7666584B2 (en) * 2005-09-01 2010-02-23 Philadelphia Health & Education Coporation Identification of a pin specific gene and protein (PIN-1) useful as a diagnostic treatment for prostate cancer
US7993832B2 (en) 2006-08-14 2011-08-09 Xdx, Inc. Methods and compositions for diagnosing and monitoring the status of transplant rejection and immune disorders
WO2008140484A2 (en) 2006-11-09 2008-11-20 Xdx, Inc. Methods for diagnosing and monitoring the status of systemic lupus erythematosus
EP2764874A1 (de) 2007-07-17 2014-08-13 The General Hospital Corporation Verfahren zur Identifizierung und Anreicherung von Populationen von Eierstockkrebsstammzellen und somatischen Stammzellen, und Verwendungen davon
WO2010008486A2 (en) * 2008-06-24 2010-01-21 Parkinsons Institute Pluripotent cell lines and methods of use thereof
EP3530730B1 (de) 2011-10-31 2022-07-20 Riken Verfahren zur stammzellenkultivierung

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5480784A (en) * 1989-07-11 1996-01-02 Gen-Probe Incorporated Nucleic acid sequence amplification methods
WO1992022651A1 (en) * 1991-06-14 1992-12-23 Isis Pharmaceuticals, Inc. Antisense oligonucleotide inhibition of the ras gene
WO1993018176A1 (en) * 1992-03-11 1993-09-16 Dana-Farber Cancer Institute METHODS TO CLONE mRNA
US6110680A (en) * 1993-11-12 2000-08-29 The Scripps Research Institute Method for simultaneous identification of differentially expressed mRNAs and measurement of relative concentrations
US5459037A (en) * 1993-11-12 1995-10-17 The Scripps Research Institute Method for simultaneous identification of differentially expressed mRNAs and measurement of relative concentrations
US6096503A (en) * 1993-11-12 2000-08-01 The Scripps Research Institute Method for simultaneous identification of differentially expresses mRNAs and measurement of relative concentrations
US5866330A (en) * 1995-09-12 1999-02-02 The Johns Hopkins University School Of Medicine Method for serial analysis of gene expression
US5994068A (en) * 1997-03-11 1999-11-30 Wisconsin Alumni Research Foundation Nucleic acid indexing

Also Published As

Publication number Publication date
WO1995013369A1 (en) 1995-05-18
US5807680A (en) 1998-09-15
NO961902L (no) 1996-07-12
US5459037A (en) 1995-10-17
AU687127B2 (en) 1998-02-19
EP0726946A4 (de) 1999-02-10
FI962000A (fi) 1996-05-10
CA2174966A1 (en) 1995-05-18
AU1055195A (en) 1995-05-29
DE69433210D1 (de) 2003-11-06
US6030784A (en) 2000-02-29
FI962000A0 (fi) 1996-05-10
US20020127571A1 (en) 2002-09-12
NO961902D0 (no) 1996-05-10
US6309834B1 (en) 2001-10-30
US20030092006A1 (en) 2003-05-15
EP0726946B1 (de) 2003-10-01
JPH09509306A (ja) 1997-09-22
EP0726946A1 (de) 1996-08-21

Similar Documents

Publication Publication Date Title
ATE251220T1 (de) Verfahen zur gleichzeitigen identifikation von differentielle exprimierten mrna's und zur messung ihrer relativen konzentration
MXPA00012757A (es) Metodo mejorado para identificacion simultanea de arnm expresados diferencialmente y medicion de concetraciones relativas.
Fisher et al. Patterns of epithelial expression of Fos protein suggest important role in the transition from viable to cornified cell during keratinization
Gooding et al. Smooth muscle‐specific switching of alpha‐tropomyosin mutually exclusive exon selection by specific inhibition of the strong default exon.
Luse et al. Abortive initiation by RNA polymerase II in vitro at the adenovirus 2 major late promoter.
Pagani et al. Tissue-specific splicing pattern of fibronectin messenger RNA precursor during development and aging in rat.
Breit et al. Suppression of MYC by high expression of NMYC in human neuroblastoma cells
Shanmugam et al. Ontogeny of angiotensin II type 2 (AT2) receptor mRNA in the rat
DE69229126T2 (de) Verfahren zur Herstellung von Thrombin
Gerlitz The emerging roles of heterochromatin in cell migration
CN106434982B (zh) 缺血性脑卒中相关的分子标记物及其应用
ES2018916A6 (es) Un metodo de ensayo de hibridacion de acidos nucleicos.
Sen et al. Identification of the messenger RNAs coding for the gag and env gene products of the murine mammary tumor virus
Michel et al. Clusterin/ApoJ expression is associated with neuronal apoptosis in the olfactory mucosa of the adult mouse
Denslow et al. Mechanism of mRNA binding to bovine mitochondrial ribosomes
Woodcock et al. Characteristics of enzymatic DNA methylation in cultured cells of human and hamster origin, and the effect of DNA replication inhibition
EA200100490A1 (ru) Способ индексации и определения относительной концентрации экспрессирующихся информационных рнк
Hale et al. Expression of CD44 variants in human inflammatory synovitis
Kojima et al. Expression of neuritin during liver maturation and regeneration
Dib-Hajj et al. Sodium channel mRNA in the B104 neuroblastoma cell line
Munns et al. Effects of estradiol on uterine ribonucleic acid metabolism. II. Methylation of ribosomal ribonucleic acid and trannsfer ribonucleic acid
Grayson et al. Estimation of the half-life of a secretory protein message
Sutcliffe et al. Method for simultaneous identification of differentially expressed mRNAs and measurement of relative concentrations
Goto et al. Expression and characterization of Xenopus type I collagen alpha 1 (COL1A1) during embryonic development
Blumberg et al. Biosynthesis and supramolecular assembly of procollagen IV in neonatal lung.

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties