ATE24664T1 - Arzneimittel mit programmierter abgabe, assoziierend acetylsalicylsaeure mit dihydroergotamine. - Google Patents
Arzneimittel mit programmierter abgabe, assoziierend acetylsalicylsaeure mit dihydroergotamine.Info
- Publication number
- ATE24664T1 ATE24664T1 AT84400032T AT84400032T ATE24664T1 AT E24664 T1 ATE24664 T1 AT E24664T1 AT 84400032 T AT84400032 T AT 84400032T AT 84400032 T AT84400032 T AT 84400032T AT E24664 T1 ATE24664 T1 AT E24664T1
- Authority
- AT
- Austria
- Prior art keywords
- dihydroergotamine
- weight
- acetylsalicylic acid
- microgranules
- hours
- Prior art date
Links
- HESHRHUZIWVEAJ-JGRZULCMSA-N dihydroergotamine Chemical compound C([C@H]1C(=O)N2CCC[C@H]2[C@]2(O)O[C@@](C(N21)=O)(C)NC(=O)[C@H]1CN([C@H]2[C@@H](C3=CC=CC4=NC=C([C]34)C2)C1)C)C1=CC=CC=C1 HESHRHUZIWVEAJ-JGRZULCMSA-N 0.000 title abstract 15
- 229960004704 dihydroergotamine Drugs 0.000 title abstract 15
- BSYNRYMUTXBXSQ-UHFFFAOYSA-N Aspirin Chemical compound CC(=O)OC1=CC=CC=C1C(O)=O BSYNRYMUTXBXSQ-UHFFFAOYSA-N 0.000 title abstract 7
- 229960001138 acetylsalicylic acid Drugs 0.000 title abstract 7
- 229940079593 drug Drugs 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
- 239000002245 particle Substances 0.000 abstract 6
- CERQOIWHTDAKMF-UHFFFAOYSA-N Methacrylic acid Chemical compound CC(=C)C(O)=O CERQOIWHTDAKMF-UHFFFAOYSA-N 0.000 abstract 4
- 239000011248 coating agent Substances 0.000 abstract 4
- 238000000576 coating method Methods 0.000 abstract 4
- 238000013270 controlled release Methods 0.000 abstract 4
- 239000000203 mixture Substances 0.000 abstract 4
- 150000003839 salts Chemical class 0.000 abstract 4
- BSYNRYMUTXBXSQ-FOQJRBATSA-N 59096-14-9 Chemical compound CC(=O)OC1=CC=CC=C1[14C](O)=O BSYNRYMUTXBXSQ-FOQJRBATSA-N 0.000 abstract 2
- 239000012729 immediate-release (IR) formulation Substances 0.000 abstract 2
- 229920000642 polymer Polymers 0.000 abstract 2
- 229920000193 polymethacrylate Polymers 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 1
- 239000004531 microgranule Substances 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5084—Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/60—Salicylic acid; Derivatives thereof
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8301577A FR2539989B1 (fr) | 1983-01-28 | 1983-01-28 | Medicament a liberation programmee associant l'acide acetylsalicylique a la dihydroergotamine |
| EP84400032A EP0117164B1 (de) | 1983-01-28 | 1984-01-06 | Arzneimittel mit programmierter Abgabe, assoziierend Acetylsalicylsäure mit Dihydroergotamine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE24664T1 true ATE24664T1 (de) | 1987-01-15 |
Family
ID=9285510
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT84400032T ATE24664T1 (de) | 1983-01-28 | 1984-01-06 | Arzneimittel mit programmierter abgabe, assoziierend acetylsalicylsaeure mit dihydroergotamine. |
Country Status (4)
| Country | Link |
|---|---|
| EP (1) | EP0117164B1 (de) |
| AT (1) | ATE24664T1 (de) |
| DE (1) | DE3461889D1 (de) |
| FR (1) | FR2539989B1 (de) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK469989D0 (da) * | 1989-09-22 | 1989-09-22 | Bukh Meditec | Farmaceutisk praeparat |
| IE64128B1 (en) * | 1990-02-26 | 1995-07-12 | Byrne Rynne Holdings Ltd | A pharmaceutical composition |
| WO1997002019A1 (en) | 1995-06-30 | 1997-01-23 | Baylor University | Polyester/carboxylic acid composite materials |
| US6586458B1 (en) | 1996-08-16 | 2003-07-01 | Pozen Inc. | Methods of treating headaches using 5-HT agonists in combination with long-acting NSAIDs |
| US8022095B2 (en) | 1996-08-16 | 2011-09-20 | Pozen, Inc. | Methods of treating headaches using 5-HT agonists in combination with long-acting NSAIDs |
| US5872145A (en) * | 1996-08-16 | 1999-02-16 | Pozen, Inc. | Formulation of 5-HT agonist and NSAID for treatment of migraine |
| CA2509023C (en) | 2002-12-26 | 2011-05-24 | Pozen Inc. | Multilayer dosage forms containing nsaids and triptans |
| EP1550452A1 (de) * | 2003-12-29 | 2005-07-06 | Boehringer Ingelheim International GmbH | Behandlung von chronischer venöser Insuffizienz mit einem Extrakt aus Blättern von roten Weinreben und einem antithrombotischen Mittel |
| GB0501809D0 (en) * | 2005-01-28 | 2005-03-09 | Pharmakodex Ltd | Anti-migraine formulations |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2444460A1 (fr) * | 1978-12-22 | 1980-07-18 | Panoz Donald | Nouvelle forme galenique a usage oral, et son procede de preparation |
| FR2453639A1 (fr) * | 1979-04-09 | 1980-11-07 | Sanofi Sa | Composition medicamenteuse a liberation programmee immediate-retard a base de naftidrofuryl |
| FR2453640A1 (fr) * | 1979-04-12 | 1980-11-07 | Labaz | Compositions therapeutiques a usage oral et a liberation programmee du methanesulfonate de dihydroergotamine |
| FR2454804B1 (fr) * | 1979-04-26 | 1986-11-21 | Sanofi Sa | Medicament a base de dihydroergotoxine et son procede de preparation |
| FR2477015A1 (fr) * | 1980-03-03 | 1981-09-04 | Fabre Sa Pierre | Composition pharmaceutique a base d'un alcaloide de l'ergot de seigle, a activite regulatrice sur le tonus vasculaire |
| ATE14379T1 (de) * | 1981-04-27 | 1985-08-15 | Haessle Ab | Pharmazeutisches praeparat. |
-
1983
- 1983-01-28 FR FR8301577A patent/FR2539989B1/fr not_active Expired
-
1984
- 1984-01-06 AT AT84400032T patent/ATE24664T1/de not_active IP Right Cessation
- 1984-01-06 DE DE8484400032T patent/DE3461889D1/de not_active Expired
- 1984-01-06 EP EP84400032A patent/EP0117164B1/de not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| EP0117164A1 (de) | 1984-08-29 |
| FR2539989A1 (fr) | 1984-08-03 |
| EP0117164B1 (de) | 1987-01-07 |
| DE3461889D1 (en) | 1987-02-12 |
| FR2539989B1 (fr) | 1985-08-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |