ATE241639T1 - Keratinozyten-wachstumsfaktor 2 - Google Patents
Keratinozyten-wachstumsfaktor 2Info
- Publication number
- ATE241639T1 ATE241639T1 AT95911700T AT95911700T ATE241639T1 AT E241639 T1 ATE241639 T1 AT E241639T1 AT 95911700 T AT95911700 T AT 95911700T AT 95911700 T AT95911700 T AT 95911700T AT E241639 T1 ATE241639 T1 AT E241639T1
- Authority
- AT
- Austria
- Prior art keywords
- disclosed
- polypeptide
- kgf
- growth factor
- keratinocyte growth
- Prior art date
Links
- 102000004864 Fibroblast growth factor 10 Human genes 0.000 title 1
- 108090001047 Fibroblast growth factor 10 Proteins 0.000 title 1
- 229920001184 polypeptide Polymers 0.000 abstract 5
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 5
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 5
- 238000000034 method Methods 0.000 abstract 2
- 201000004384 Alopecia Diseases 0.000 abstract 1
- 108091026890 Coding region Proteins 0.000 abstract 1
- 108020004414 DNA Proteins 0.000 abstract 1
- 208000007766 Kaposi sarcoma Diseases 0.000 abstract 1
- 208000002260 Keloid Diseases 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 201000004681 Psoriasis Diseases 0.000 abstract 1
- 208000017442 Retinal disease Diseases 0.000 abstract 1
- 206010038923 Retinopathy Diseases 0.000 abstract 1
- 230000004075 alteration Effects 0.000 abstract 1
- 239000005557 antagonist Substances 0.000 abstract 1
- 201000011510 cancer Diseases 0.000 abstract 1
- 230000010261 cell growth Effects 0.000 abstract 1
- 238000002405 diagnostic procedure Methods 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 210000002919 epithelial cell Anatomy 0.000 abstract 1
- 208000024963 hair loss Diseases 0.000 abstract 1
- 230000003676 hair loss Effects 0.000 abstract 1
- 210000001117 keloid Anatomy 0.000 abstract 1
- 230000035772 mutation Effects 0.000 abstract 1
- 230000002062 proliferating effect Effects 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 238000010188 recombinant method Methods 0.000 abstract 1
- 208000037803 restenosis Diseases 0.000 abstract 1
- 230000037390 scarring Effects 0.000 abstract 1
- 230000004936 stimulating effect Effects 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
- 230000029663 wound healing Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/50—Fibroblast growth factor [FGF]
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
- C12N15/1136—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against growth factors, growth regulators, cytokines, lymphokines or hormones
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6863—Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2799/00—Uses of viruses
- C12N2799/02—Uses of viruses as vector
- C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
- C12N2799/026—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a baculovirus
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Wood Science & Technology (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Biophysics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biotechnology (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Physics & Mathematics (AREA)
- Gastroenterology & Hepatology (AREA)
- Pathology (AREA)
- Toxicology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Cell Biology (AREA)
- Epidemiology (AREA)
- Cardiology (AREA)
- Plant Pathology (AREA)
- Endocrinology (AREA)
- Heart & Thoracic Surgery (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/US1995/001790 WO1996025422A1 (en) | 1995-02-14 | 1995-02-14 | Keratinocyte growth factor-2 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE241639T1 true ATE241639T1 (de) | 2003-06-15 |
Family
ID=22248657
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT95911700T ATE241639T1 (de) | 1995-02-14 | 1995-02-14 | Keratinozyten-wachstumsfaktor 2 |
Country Status (10)
| Country | Link |
|---|---|
| EP (2) | EP0815115B1 (de) |
| JP (1) | JP3774230B2 (de) |
| KR (1) | KR19980702186A (de) |
| AT (1) | ATE241639T1 (de) |
| AU (1) | AU708868B2 (de) |
| CA (1) | CA2210444C (de) |
| DE (1) | DE69530944T2 (de) |
| DK (1) | DK0815115T3 (de) |
| NZ (1) | NZ282146A (de) |
| WO (1) | WO1996025422A1 (de) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6693077B1 (en) | 1995-02-14 | 2004-02-17 | Human Genome Sciences, Inc. | Keratinocyte growth factor-2 |
| US7232667B2 (en) | 1995-02-14 | 2007-06-19 | Human Genome Sciences, Inc. | Keratinocyte growth factor-2 polynucleotides |
| US6077692A (en) | 1995-02-14 | 2000-06-20 | Human Genome Sciences, Inc. | Keratinocyte growth factor-2 |
| WO1997020929A1 (fr) * | 1995-12-07 | 1997-06-12 | Sumitomo Pharmaceuticals Company, Limited | Facteur de croissance des fibroblastes fgf-10 |
| AU739773B2 (en) * | 1996-08-13 | 2001-10-18 | Human Genome Sciences, Inc. | Keratinocyte growth factor-2 (KGF-2 or fibroblast growth factor-12, FGF-12) |
| AU775027C (en) * | 1996-10-15 | 2005-12-08 | Biovitrum Ab (Publ) | Keratinocyte growth factor-2 products |
| DK0935652T3 (da) * | 1996-10-15 | 2004-07-26 | Amgen Inc | Keratinocyt vækstfaktor-2 produkter |
| US6743422B1 (en) | 1996-10-15 | 2004-06-01 | Amgen, Inc. | Keratinocyte growth factor-2 products |
| DE69727691T2 (de) * | 1996-10-15 | 2004-07-22 | Amgen Inc., Thousand Oaks | Verwendung von keratinocyten-wachstumsfaktor-2 |
| EP1473366A1 (de) * | 1996-10-15 | 2004-11-03 | Amgen Inc. | Produkte des Keratinocyten-Wachstumsfaktors 2 |
| EP1452205B1 (de) * | 1996-10-15 | 2007-11-28 | Amgen Inc. | Verwendung von keratinocyte growth factor-2 |
| EP1041996A4 (de) | 1997-12-22 | 2003-05-14 | Human Genome Sciences Inc | Keratinozyten wachstumsfaktor-2 formulierungen |
| US6869927B1 (en) | 1997-12-22 | 2005-03-22 | Human Genome Sciences, Inc. | Keratinocyte growth factor-2 formulations |
| CA2320515A1 (en) * | 1998-02-13 | 1999-08-19 | Human Genome Sciences, Inc. | Therapeutic uses of keratinocyte growth factor-2 |
| US6706721B1 (en) | 1998-04-29 | 2004-03-16 | Osi Pharmaceuticals, Inc. | N-(3-ethynylphenylamino)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine mesylate anhydrate and monohydrate |
| UA74803C2 (uk) | 1999-11-11 | 2006-02-15 | Осі Фармасьютікалз, Інк. | Стійкий поліморф гідрохлориду n-(3-етинілфеніл)-6,7-біс(2-метоксіетокси)-4-хіназолінаміну, спосіб його одержання (варіанти) та фармацевтичне застосування |
| US7087613B2 (en) | 1999-11-11 | 2006-08-08 | Osi Pharmaceuticals, Inc. | Treating abnormal cell growth with a stable polymorph of N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine hydrochloride |
| WO2001042449A2 (en) * | 1999-12-10 | 2001-06-14 | Anticancer, Inc. | Methods for introducing genes into mammalian subjects |
| US20020061304A1 (en) | 2000-03-20 | 2002-05-23 | Pfizer Products Inc. & Osi Pharmaceuticals, Inc. | Combined treatment with keratinocyte growth factor and epidermal growth factor inhibitor |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100390340B1 (ko) * | 1993-03-26 | 2003-09-26 | 암겐 인코포레이티드 | 케라티노사이트성장인자산물을함유하는제약학적조성물 |
-
1995
- 1995-02-14 DE DE69530944T patent/DE69530944T2/de not_active Expired - Fee Related
- 1995-02-14 NZ NZ282146A patent/NZ282146A/en unknown
- 1995-02-14 WO PCT/US1995/001790 patent/WO1996025422A1/en not_active Application Discontinuation
- 1995-02-14 KR KR1019970705581A patent/KR19980702186A/ko not_active Application Discontinuation
- 1995-02-14 JP JP52490596A patent/JP3774230B2/ja not_active Expired - Fee Related
- 1995-02-14 CA CA002210444A patent/CA2210444C/en not_active Expired - Fee Related
- 1995-02-14 EP EP95911700A patent/EP0815115B1/de not_active Expired - Lifetime
- 1995-02-14 AU AU19171/95A patent/AU708868B2/en not_active Ceased
- 1995-02-14 EP EP03006708A patent/EP1323824A3/de not_active Withdrawn
- 1995-02-14 DK DK95911700T patent/DK0815115T3/da active
- 1995-02-14 AT AT95911700T patent/ATE241639T1/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| EP0815115B1 (de) | 2003-05-28 |
| DK0815115T3 (da) | 2003-09-15 |
| CA2210444C (en) | 2003-07-29 |
| WO1996025422A1 (en) | 1996-08-22 |
| EP1323824A2 (de) | 2003-07-02 |
| JP3774230B2 (ja) | 2006-05-10 |
| EP0815115A4 (de) | 1999-09-22 |
| DE69530944D1 (de) | 2003-07-03 |
| AU1917195A (en) | 1996-09-04 |
| AU708868B2 (en) | 1999-08-12 |
| EP1323824A3 (de) | 2004-01-21 |
| CA2210444A1 (en) | 1996-08-22 |
| JPH10509328A (ja) | 1998-09-14 |
| EP0815115A1 (de) | 1998-01-07 |
| KR19980702186A (ko) | 1998-07-15 |
| NZ282146A (en) | 1999-10-28 |
| DE69530944T2 (de) | 2004-03-11 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 0815115 Country of ref document: EP |
|
| REN | Ceased due to non-payment of the annual fee |