ATE236926T1 - Herstellung von immunglobulin - Google Patents
Herstellung von immunglobulinInfo
- Publication number
- ATE236926T1 ATE236926T1 AT96913551T AT96913551T ATE236926T1 AT E236926 T1 ATE236926 T1 AT E236926T1 AT 96913551 T AT96913551 T AT 96913551T AT 96913551 T AT96913551 T AT 96913551T AT E236926 T1 ATE236926 T1 AT E236926T1
- Authority
- AT
- Austria
- Prior art keywords
- treated
- pepsin
- immunoglobulin
- immunolobulin
- production
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 102000057297 Pepsin A Human genes 0.000 abstract 2
- 108090000284 Pepsin A Proteins 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 229940111202 pepsin Drugs 0.000 abstract 2
- 108060003951 Immunoglobulin Proteins 0.000 abstract 1
- 241000700605 Viruses Species 0.000 abstract 1
- 230000004913 activation Effects 0.000 abstract 1
- 239000008280 blood Substances 0.000 abstract 1
- 210000004369 blood Anatomy 0.000 abstract 1
- 238000000354 decomposition reaction Methods 0.000 abstract 1
- 102000018358 immunoglobulin Human genes 0.000 abstract 1
- 229940027941 immunoglobulin g Drugs 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/06—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies from serum
- C07K16/065—Purification, fragmentation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
- A61L2/0011—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using physical methods
- A61L2/0017—Filtration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
- A61L2/0082—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using chemical substances
- A61L2/0088—Liquid substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/02—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using physical phenomena
- A61L2/022—Filtration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/16—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using chemical substances
- A61L2/18—Liquid substances or solutions comprising solids or dissolved gases
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
- C12N7/04—Inactivation or attenuation; Producing viral sub-units
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
- C12N7/04—Inactivation or attenuation; Producing viral sub-units
- C12N7/06—Inactivation or attenuation by chemical treatment
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Genetics & Genomics (AREA)
- Epidemiology (AREA)
- Public Health (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Virology (AREA)
- General Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Engineering & Computer Science (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FI952196A FI952196A0 (fi) | 1995-05-08 | 1995-05-08 | Framstaellning av immunoglobulin |
PCT/FI1996/000254 WO1996035710A1 (en) | 1995-05-08 | 1996-05-07 | Preparation of immunoglobulin |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE236926T1 true ATE236926T1 (de) | 2003-04-15 |
Family
ID=8543365
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT96913551T ATE236926T1 (de) | 1995-05-08 | 1996-05-07 | Herstellung von immunglobulin |
Country Status (9)
Country | Link |
---|---|
US (3) | US20020128453A1 (de) |
EP (1) | EP0825998B1 (de) |
JP (1) | JPH11504644A (de) |
AT (1) | ATE236926T1 (de) |
AU (1) | AU700736B2 (de) |
DE (1) | DE69627319T2 (de) |
DK (1) | DK0825998T3 (de) |
FI (1) | FI952196A0 (de) |
WO (1) | WO1996035710A1 (de) |
Families Citing this family (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0957943B2 (de) | 1997-02-07 | 2008-11-26 | Stryker Corporation | Matrixlose osteogene vorrichtungen und implantate und verfahren zu deren verwendung |
US6124437A (en) * | 1997-03-19 | 2000-09-26 | Welfide Corporation | Immunoglobulin preparation and preparation process thereof |
GB9705810D0 (en) * | 1997-03-20 | 1997-05-07 | Common Services Agency | Intravenous immune globulin |
US7041641B2 (en) | 1997-03-20 | 2006-05-09 | Stryker Corporation | Osteogenic devices and methods of use thereof for repair of endochondral bone and osteochondral defects |
ES2160410T3 (es) | 1997-04-08 | 2001-11-01 | Baxter Ag | Preparados de complejos de protrombina inmunotolerantes. |
AT405608B (de) * | 1997-04-08 | 1999-10-25 | Immuno Ag | Verfahren zur inaktivierung von pathogenen, insbesondere von viren, in einem biologischen material |
AT406873B (de) * | 1998-02-25 | 2000-10-25 | Immuno Ag | Verfahren zur abreicherung von pathogenen aus proteinhaltigen lösungen |
JP5525118B2 (ja) | 2002-09-11 | 2014-06-18 | 中外製薬株式会社 | タンパク質精製方法 |
TWI391399B (zh) * | 2005-05-25 | 2013-04-01 | Hoffmann La Roche | 測定溶離多肽之鹽濃度之方法 |
US20070128693A1 (en) * | 2005-12-06 | 2007-06-07 | Advantek Serum Laboratories Limited3/F | Method for the inactivation and removal of dengue virus from biological samples |
JP4857323B2 (ja) * | 2008-10-17 | 2012-01-18 | 田辺三菱製薬株式会社 | 免疫グロブリン製剤 |
EP3275897A1 (de) | 2016-07-27 | 2018-01-31 | Biotest AG | Verfahren zur herstellung von immunoglobulinzusammensetzungen |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3966906A (en) * | 1961-10-11 | 1976-06-29 | Behringwerke Aktiengesellschaft | Disaggregated gamma globulin and process for preparing it |
JPS57206608A (en) * | 1981-05-29 | 1982-12-18 | Mochida Pharmaceut Co Ltd | Production of gamma-globulin for intravenous injection |
US4481189A (en) * | 1982-04-14 | 1984-11-06 | New York Blood Center Inc. | Process for preparing sterilized plasma and plasma derivatives |
US4591505A (en) * | 1982-04-14 | 1986-05-27 | New York Blood Center, Inc. | Process for inactivating hepatitis B virus |
US4540573A (en) * | 1983-07-14 | 1985-09-10 | New York Blood Center, Inc. | Undenatured virus-free biologically active protein derivatives |
US4613501A (en) * | 1984-12-21 | 1986-09-23 | New York Blood Center, Inc. | Inactivation of viruses in labile blood derivatives |
FR2582515B1 (fr) * | 1985-05-30 | 1988-11-04 | Merieux Inst | Procede de preparation de gamma-gobulines administrables par voie intraveineuse et gamma-globulines obtenues |
GB8628104D0 (en) * | 1986-11-25 | 1986-12-31 | Connaught Lab | Pasteurization of immunoglobin solutions |
US5118796A (en) * | 1987-12-09 | 1992-06-02 | Centocor, Incorporated | Efficient large-scale purification of immunoglobulins and derivatives |
CA2007545A1 (en) * | 1989-01-13 | 1990-07-13 | Yahiro Uemura | Production method for protein-containing composition |
JPH0778025B2 (ja) * | 1990-03-20 | 1995-08-23 | 日本赤十字社 | 免疫グロブリンgの製造方法 |
US5506127A (en) * | 1994-09-21 | 1996-04-09 | Proba; Zbigniew | Therapeutic grade thrombin produced by chromatography |
-
1995
- 1995-05-08 FI FI952196A patent/FI952196A0/fi not_active Application Discontinuation
-
1996
- 1996-05-07 JP JP8533805A patent/JPH11504644A/ja not_active Ceased
- 1996-05-07 EP EP96913551A patent/EP0825998B1/de not_active Expired - Lifetime
- 1996-05-07 WO PCT/FI1996/000254 patent/WO1996035710A1/en active IP Right Grant
- 1996-05-07 US US08/952,199 patent/US20020128453A1/en not_active Abandoned
- 1996-05-07 AU AU56500/96A patent/AU700736B2/en not_active Ceased
- 1996-05-07 AT AT96913551T patent/ATE236926T1/de not_active IP Right Cessation
- 1996-05-07 DE DE69627319T patent/DE69627319T2/de not_active Expired - Lifetime
- 1996-05-07 DK DK96913551T patent/DK0825998T3/da active
-
2003
- 2003-08-06 US US10/635,859 patent/US20040106780A1/en not_active Abandoned
-
2005
- 2005-09-20 US US11/231,358 patent/US20060177909A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
DE69627319D1 (de) | 2003-05-15 |
EP0825998B1 (de) | 2003-04-09 |
JPH11504644A (ja) | 1999-04-27 |
WO1996035710A1 (en) | 1996-11-14 |
AU700736B2 (en) | 1999-01-14 |
AU5650096A (en) | 1996-11-29 |
DK0825998T3 (da) | 2003-08-04 |
US20020128453A1 (en) | 2002-09-12 |
US20040106780A1 (en) | 2004-06-03 |
EP0825998A1 (de) | 1998-03-04 |
US20060177909A1 (en) | 2006-08-10 |
DE69627319T2 (de) | 2004-02-12 |
FI952196A0 (fi) | 1995-05-08 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |