ATE228375T1 - THIOMOLYBDAT VERBUNDEN MIT MINDESTENS EINEM KOHLENHYDRAT, UND SEINE VERWENDUNG ZUR VORBEUGUNG UND BEHANDLUNG VON ERKRANKUNGEN, DIE DURCH EINE ANORMALE VASKULARISIERUNG GEKENNZEICHNET SIND, WIE Z.B. KREBS, ßFEUCHTEß MAKULADEGENERATION, RHEUMATOIDE ARTHRITIS - Google Patents
THIOMOLYBDAT VERBUNDEN MIT MINDESTENS EINEM KOHLENHYDRAT, UND SEINE VERWENDUNG ZUR VORBEUGUNG UND BEHANDLUNG VON ERKRANKUNGEN, DIE DURCH EINE ANORMALE VASKULARISIERUNG GEKENNZEICHNET SIND, WIE Z.B. KREBS, ßFEUCHTEß MAKULADEGENERATION, RHEUMATOIDE ARTHRITISInfo
- Publication number
- ATE228375T1 ATE228375T1 AT99952903T AT99952903T ATE228375T1 AT E228375 T1 ATE228375 T1 AT E228375T1 AT 99952903 T AT99952903 T AT 99952903T AT 99952903 T AT99952903 T AT 99952903T AT E228375 T1 ATE228375 T1 AT E228375T1
- Authority
- AT
- Austria
- Prior art keywords
- prevention
- treatment
- cancer
- thiomolybdate
- carbohydrate
- Prior art date
Links
- 206010028980 Neoplasm Diseases 0.000 title abstract 3
- 201000010099 disease Diseases 0.000 title abstract 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title abstract 3
- 201000011510 cancer Diseases 0.000 title abstract 2
- 230000002265 prevention Effects 0.000 title abstract 2
- 230000002159 abnormal effect Effects 0.000 title 1
- 150000001720 carbohydrates Chemical class 0.000 title 1
- 208000002780 macular degeneration Diseases 0.000 title 1
- 206010039073 rheumatoid arthritis Diseases 0.000 title 1
- CXVCSRUYMINUSF-UHFFFAOYSA-N tetrathiomolybdate(2-) Chemical compound [S-][Mo]([S-])(=S)=S CXVCSRUYMINUSF-UHFFFAOYSA-N 0.000 title 1
- 239000003795 chemical substances by application Substances 0.000 abstract 2
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 abstract 1
- 238000002648 combination therapy Methods 0.000 abstract 1
- 229910052802 copper Inorganic materials 0.000 abstract 1
- 239000010949 copper Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
- 230000002792 vascular Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/28—Compounds containing heavy metals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/34—Copper; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/243—Platinum; Compounds thereof
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Inorganic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Heart & Thoracic Surgery (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Cardiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Compounds Of Unknown Constitution (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US9910398P | 1998-09-04 | 1998-09-04 | |
| US10175998P | 1998-09-25 | 1998-09-25 | |
| PCT/US1999/020374 WO2000013712A2 (en) | 1998-09-04 | 1999-09-03 | Methods and compositions for the prevention or treatment of cancer |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE228375T1 true ATE228375T1 (de) | 2002-12-15 |
Family
ID=26795562
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT99952903T ATE228375T1 (de) | 1998-09-04 | 1999-09-03 | THIOMOLYBDAT VERBUNDEN MIT MINDESTENS EINEM KOHLENHYDRAT, UND SEINE VERWENDUNG ZUR VORBEUGUNG UND BEHANDLUNG VON ERKRANKUNGEN, DIE DURCH EINE ANORMALE VASKULARISIERUNG GEKENNZEICHNET SIND, WIE Z.B. KREBS, ßFEUCHTEß MAKULADEGENERATION, RHEUMATOIDE ARTHRITIS |
Country Status (14)
| Country | Link |
|---|---|
| EP (1) | EP1107795B1 (de) |
| JP (1) | JP2002524426A (de) |
| KR (1) | KR100702279B1 (de) |
| CN (1) | CN100548383C (de) |
| AT (1) | ATE228375T1 (de) |
| AU (1) | AU773848B2 (de) |
| CA (1) | CA2341752A1 (de) |
| DE (1) | DE69904203T2 (de) |
| DK (1) | DK1107795T3 (de) |
| ES (1) | ES2188261T3 (de) |
| IL (1) | IL141550A0 (de) |
| NZ (1) | NZ510038A (de) |
| PT (1) | PT1107795E (de) |
| WO (1) | WO2000013712A2 (de) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6703050B1 (en) | 1998-09-04 | 2004-03-09 | The Regents Of The University Of Michigan | Methods and compositions for the prevention or treatment of cancer |
| US7592304B2 (en) | 1999-10-01 | 2009-09-22 | Dmi Life Sciences, Inc. | Metal-binding compounds and uses therefor |
| US7632803B2 (en) | 1999-10-01 | 2009-12-15 | Dmi Life Sciences, Inc. | Metal-binding compounds and uses therefor |
| US20070292533A1 (en) * | 2002-05-24 | 2007-12-20 | Regents Of The University Of Michigan | Copper lowering treatment of autoimmune diseases |
| EP1531827A4 (de) * | 2002-05-24 | 2009-07-08 | Univ Michigan | Kupfer-verringernde behandlung für entzündliche und fibrotische erkrankungen |
| US7189865B2 (en) * | 2002-07-23 | 2007-03-13 | Attenuon, Llc | Thiomolybdate analogues and uses thereof |
| EP1539131A4 (de) | 2002-07-23 | 2009-07-08 | Univ Michigan | Tetrapropylammoniumtetrathiomolybdat und verwandte verbindungen für anti-angiogene therapien |
| PL218366B1 (pl) * | 2003-05-27 | 2014-11-28 | Attenuon | Pochodna tiowolframianu i jej zastosowanie oraz kompozycja farmaceutyczna i jej zastosowanie |
| EP1721010A2 (de) * | 2004-02-24 | 2006-11-15 | Attenuon, LLC | Hemmung der superoxiddismutase durch tetrathiomolybdate: identifizierung neuen anti-angiogenisch- und antitumormittel |
| WO2007084818A2 (en) * | 2006-01-10 | 2007-07-26 | Pipex, Inc. | Pharmaceutical compositions and methods to achieve and maintain a targeted and stable copper status and prevent and treat copper-related central nervous system diseases |
| WO2009009622A2 (en) * | 2007-07-09 | 2009-01-15 | Pipex Pharmaceuticals, Inc. | Pharmaceutical compositions, including attm, and methods to achieve and maintain a targeted and stable copper status and prevent and treat copper-related central nervous system diseases |
| KR100972355B1 (ko) * | 2008-05-08 | 2010-07-26 | 고려전자주식회사 | 순간식 가스보일러의 온수공급라인용 써모밸브조립체 |
| GB201005394D0 (en) * | 2010-03-30 | 2010-05-12 | Magnus Intellectual Property Ltd | Therapy |
| US10478455B2 (en) | 2010-03-30 | 2019-11-19 | Ucl Business Ltd | Therapeutic use of tetrathiomolybdate |
| US20160220500A1 (en) * | 2014-11-14 | 2016-08-04 | Kent State University | Targeting Intracellular Copper Ions for Inhibiting Angiogenesis Using Nanoparticles of Ternary Inorganic Metal Sulfide M1M2S4 (M1, independently, is Mg, Ca, Mn, Fe, or Zn; M2 = Mo or W) Compounds to Treat Metastatic Cancer |
| CN108634322A (zh) * | 2018-05-16 | 2018-10-12 | 刘华 | 一种预防和调理癌症的方法 |
| CN119258070A (zh) * | 2018-06-01 | 2025-01-07 | 因赛特公司 | 治疗pi3k相关病症的给药方案 |
-
1999
- 1999-09-03 JP JP2000568518A patent/JP2002524426A/ja active Pending
- 1999-09-03 AT AT99952903T patent/ATE228375T1/de not_active IP Right Cessation
- 1999-09-03 AU AU64960/99A patent/AU773848B2/en not_active Ceased
- 1999-09-03 EP EP99952903A patent/EP1107795B1/de not_active Expired - Lifetime
- 1999-09-03 KR KR1020017002840A patent/KR100702279B1/ko not_active Expired - Fee Related
- 1999-09-03 CA CA002341752A patent/CA2341752A1/en not_active Abandoned
- 1999-09-03 CN CNB998117331A patent/CN100548383C/zh not_active Expired - Fee Related
- 1999-09-03 IL IL14155099A patent/IL141550A0/xx unknown
- 1999-09-03 ES ES99952903T patent/ES2188261T3/es not_active Expired - Lifetime
- 1999-09-03 NZ NZ510038A patent/NZ510038A/en not_active IP Right Cessation
- 1999-09-03 PT PT99952903T patent/PT1107795E/pt unknown
- 1999-09-03 DK DK99952903T patent/DK1107795T3/da active
- 1999-09-03 WO PCT/US1999/020374 patent/WO2000013712A2/en not_active Ceased
- 1999-09-03 DE DE69904203T patent/DE69904203T2/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| DE69904203D1 (de) | 2003-01-09 |
| WO2000013712A3 (en) | 2000-09-28 |
| WO2000013712A2 (en) | 2000-03-16 |
| AU773848B2 (en) | 2004-06-10 |
| EP1107795B1 (de) | 2002-11-27 |
| DE69904203T2 (de) | 2003-08-14 |
| IL141550A0 (en) | 2002-03-10 |
| CN1457261A (zh) | 2003-11-19 |
| DK1107795T3 (da) | 2003-03-24 |
| KR100702279B1 (ko) | 2007-04-02 |
| EP1107795A2 (de) | 2001-06-20 |
| CN100548383C (zh) | 2009-10-14 |
| KR20010082190A (ko) | 2001-08-29 |
| AU6496099A (en) | 2000-03-27 |
| PT1107795E (pt) | 2003-04-30 |
| NZ510038A (en) | 2003-10-31 |
| ES2188261T3 (es) | 2003-06-16 |
| CA2341752A1 (en) | 2000-03-16 |
| JP2002524426A (ja) | 2002-08-06 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE228375T1 (de) | THIOMOLYBDAT VERBUNDEN MIT MINDESTENS EINEM KOHLENHYDRAT, UND SEINE VERWENDUNG ZUR VORBEUGUNG UND BEHANDLUNG VON ERKRANKUNGEN, DIE DURCH EINE ANORMALE VASKULARISIERUNG GEKENNZEICHNET SIND, WIE Z.B. KREBS, ßFEUCHTEß MAKULADEGENERATION, RHEUMATOIDE ARTHRITIS | |
| HUT76970A (hu) | Készítmény az érrendszer specifikus koagulálásához | |
| WO2005000901A3 (en) | Cd20-specific antibodies and methods of employing same | |
| SI2269656T1 (sl) | Izbrana protitelesa, ki se veĹľejo na aminofosfolipide, in njihova uporaba v zdravljanju raka | |
| AU1520195A (en) | Use of anti-tnf antibodies as drugs in treating diseases involving elevated interleukin-6 serum levels | |
| WO2006029219A3 (en) | Human monoclonal anti-ctla4 antibodies in cancer treatment | |
| MX2007004551A (es) | Compuestos tiadiazol y metodos de uso. | |
| WO2001092581A3 (en) | Compositions and methods for the therapy and diagnosis of ovarian cancer | |
| BG110703A (en) | PHARMACEUTICAL COMPOSITION, INCLUDING HUMAN ANTIBODIES CONNECTING HUMAN TNF ALPHA AND HIS APPLICATION | |
| DE69902154D1 (de) | Eisen-dextran verbindung zur verwendung als komponente in einer therapeutischen zusammensetzung zur behandlung oder prophylaxe von eisenmangel, sowie verfahren zur herstellung der eisen-dextran verbindung und ihre anwendung zur herstellung einer parenteral anwendbaren therapeutischen zubereitung. | |
| DE58906239D1 (de) | Einrichtung zur Behandlung von Erkrankungen, insbesondere der Sehbahn. | |
| Sokal | Prognosis in chronic myeloid leukaemia: biology of the disease vs. treatment | |
| WO2001079164A3 (en) | N-substituted dithiocarbamates for the treatment of biological disorders | |
| WO2024178202A3 (en) | Anti-cd3 antibodies and methods for their use | |
| MX2023006777A (es) | Composiciones y métodos que comprenden antagonistas de proteína 2 relacionada con frizzled secretada (sfrp2). | |
| EP0281070A3 (de) | Pharmazeutische Zusammensetzung für die Krebsbehandlung | |
| WO2024191972A3 (en) | Anti-lipocalin-2 antibodies and uses thereof | |
| EP1401496A4 (de) | Zusammensetzungen und verfahren zur behandlung von hyperimmunreaktionen im auge | |
| WO2003013431A3 (en) | Compositions and methods for the therapy and diagnosis of breast cancer | |
| WO2003038130A3 (en) | Therapeutics and diagnostics for disorders of erythropoiesis | |
| ATE500269T1 (de) | Verbindungen mit wachstumshormon-freisetzenden eigenschaften | |
| ATE435284T1 (de) | Zusammensetzungen und verfahren zur therapie und diagnose von lungenkrebs | |
| WO2000012754A8 (en) | Method for identifying substances for the treatment of c-jun-mediated disorders | |
| WO2004013303A3 (en) | Modified annexin proteins and methods for treating vaso-occlusive sickle-cell disease | |
| WO2001098339A3 (en) | Compositions and methods for the therapy and diagnosis of breast cancer |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 1107795 Country of ref document: EP |
|
| REN | Ceased due to non-payment of the annual fee |