ATE227128T1 - Niacin enthaltende tabletten und sätze mit verzögerter wirkstoffabgabe - Google Patents

Niacin enthaltende tabletten und sätze mit verzögerter wirkstoffabgabe

Info

Publication number
ATE227128T1
ATE227128T1 AT93401681T AT93401681T ATE227128T1 AT E227128 T1 ATE227128 T1 AT E227128T1 AT 93401681 T AT93401681 T AT 93401681T AT 93401681 T AT93401681 T AT 93401681T AT E227128 T1 ATE227128 T1 AT E227128T1
Authority
AT
Austria
Prior art keywords
sustained
release tablets
sets containing
containing niacin
niacin
Prior art date
Application number
AT93401681T
Other languages
English (en)
Inventor
Victoria A O'neill
Kenneth L Evenstad
Original Assignee
Kos Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25421462&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE227128(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Kos Pharma Inc filed Critical Kos Pharma Inc
Application granted granted Critical
Publication of ATE227128T1 publication Critical patent/ATE227128T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/455—Nicotinic acids, e.g. niacin; Derivatives thereof, e.g. esters, amides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
AT93401681T 1992-06-29 1993-06-29 Niacin enthaltende tabletten und sätze mit verzögerter wirkstoffabgabe ATE227128T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/905,785 US5268181A (en) 1989-04-13 1992-06-29 Method of using niacin to control nocturnal cholesterol synthesis

Publications (1)

Publication Number Publication Date
ATE227128T1 true ATE227128T1 (de) 2002-11-15

Family

ID=25421462

Family Applications (1)

Application Number Title Priority Date Filing Date
AT93401681T ATE227128T1 (de) 1992-06-29 1993-06-29 Niacin enthaltende tabletten und sätze mit verzögerter wirkstoffabgabe

Country Status (7)

Country Link
US (1) US5268181A (de)
EP (3) EP0577504B1 (de)
AT (1) ATE227128T1 (de)
DE (1) DE69332463T2 (de)
DK (1) DK0577504T3 (de)
ES (1) ES2186674T3 (de)
PT (1) PT577504E (de)

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US5721221A (en) * 1991-03-08 1998-02-24 Regents Of The University Of Minnesota Lowering blood cholesterol levels using water soluble cellulose ethers
DE4329794C2 (de) * 1993-09-03 1997-09-18 Gruenenthal Gmbh Tramadolsalz enthaltende Arzneimittel mit verzögerter Wirkstofffreisetzung
US6080428A (en) 1993-09-20 2000-06-27 Bova; David J. Nicotinic acid compositions for treating hyperlipidemia and related methods therefor
EP0643965B1 (de) * 1993-09-20 2013-05-08 Abbott Laboratories Nicotinsäure enthaltende Zusammensetzungen zur Behandlung der Hyperlipidämie
US6129930A (en) 1993-09-20 2000-10-10 Bova; David J. Methods and sustained release nicotinic acid compositions for treating hyperlipidemia at night
US20080045573A1 (en) * 1993-09-20 2008-02-21 Bova David J Methods and Sustained Release Nicotinic Acid Compositions for Treating Hyperlipidemia
US6406715B1 (en) * 1993-09-20 2002-06-18 Kos Pharmaceuticals, Inc. Intermediate release nicotinic acid compositions for treating hyperlipidemia having unique urinary metabolite profiles
US6746691B2 (en) * 1993-09-20 2004-06-08 Kos Pharmaceuticals, Inc. Intermediate release nicotinic acid compositions for treating hyperlipidemia having unique biopharmaceutical characteristics
US20060263428A1 (en) * 1993-09-20 2006-11-23 Eugenio Cefali Methods for treating hyperlipidemia with intermediate release nicotinic acid compositions having unique biopharmaceutical characteristics
US6818229B1 (en) 1993-09-20 2004-11-16 Kos Pharmaceuticals, Inc. Intermediate release nicotinic acid compositions for treating hyperlipidemia
US6676967B1 (en) * 1993-09-20 2004-01-13 Kos Pharmaceuticals, Inc. Methods for reducing flushing in individuals being treated with nicotinic acid for hyperlipidemia
EP0821587A4 (de) * 1995-04-19 1999-05-19 Lipoprotein Technologies Inc Mittel, kits und verfahren zur verabreichung von antilipämischen und gegen die blutplättchen-aggregation wirkenden arzneistoffen
ES2191706T3 (es) * 1995-06-07 2003-09-16 Pfizer Derivados de tetrahidro-isoquinolinil-6-il amida del acido bifenil-2-carboxilico, su preparacion y su uso como inhibidores de la proteina de transferencia de trigliceridos microsomal y/o secrecion de apolipoproteina b (apo b).
US7179486B1 (en) * 1997-04-01 2007-02-20 Nostrum Pharmaceuticals, Inc. Process for preparing sustained release tablets
PT1017390E (pt) * 1997-07-31 2007-07-24 Kos Life Sciences Inc Comprimido revestido que compreende ácido nicotínico ou um composto metabolizado a ácido nicotínico sob uma forma de libertação prolongada, e um revestimento que contém um inibidor da hmg-coa-redutase sob uma forma de libertação imediata.
US20010006644A1 (en) 1997-07-31 2001-07-05 David J. Bova Combinations of hmg-coa reductase inhibitors and nicotinic acid and methods for treating hyperlipidemia once a day at night
US6469035B1 (en) * 1997-07-31 2002-10-22 Eugenio A. Cefali Methods of pretreating hyperlipidemic individuals with a flush inhibiting agent prior to the start of single daily dose nicotinic acid therapy to reduce flushing provoked by nicotinic acid
AR030557A1 (es) * 2000-04-14 2003-08-27 Jagotec Ag Una tableta en multicapa de liberacion controlada y metodo de tratamiento
UA77660C2 (en) * 2000-10-03 2007-01-15 Compositions and methods for reducing plasma lipoprotein a level in human
US7052706B2 (en) * 2001-06-08 2006-05-30 Nostrum Pharmaceuticals, Inc. Control release formulation containing a hydrophobic material as the sustained release agent
AU2005305086A1 (en) * 2004-11-05 2006-05-18 Arena Pharmaceuticals, Inc. Compositions for treating flushing and lipid-associated disorders comprising niacin receptor partial agonists
WO2006048895A1 (en) * 2004-11-08 2006-05-11 Rubicon Research Pvt. Ltd. Aqueous pharmaceutical coating
FR2878748B1 (fr) * 2004-12-07 2007-03-09 Arrow Generiques Soc Par Actio Formule de comprimes permettant une liberation prolongee d'indapamide apres administration par voie orale et procede de preparation
AU2006214286A1 (en) * 2005-02-18 2006-08-24 Arena Pharmaceuticals, Inc. Methods and compositions for the treatment of lipid-associated disorders
US20070053930A1 (en) * 2005-09-07 2007-03-08 Bebaas, Inc. Combination therapy for treatment of high cholesterol
CA2569776A1 (en) * 2006-02-17 2007-08-17 Kos Life Sciences, Inc. Low flush niacin formulation
WO2008100249A1 (en) * 2007-02-13 2008-08-21 Kos Life Sciences, Inc. Low flush niacin formulation
EP2114151A4 (de) * 2007-03-01 2010-03-17 Concourse Health Sciences Llc Isomere von inositol-niacinat und anwendungen davon
AR065670A1 (es) 2007-03-09 2009-06-24 Indigene Pharmaceuticals Inc Combinacion de metformina r-(+) lipoato y agentes antihiperlipidemicos para el tratamiento de hiperglucemia diabetica y complicaciones diabeticas
KR100836960B1 (ko) * 2007-09-07 2008-06-10 주식회사 서울제약 새로운 나이아신 제어방출형 제제
EP2296709A4 (de) * 2008-06-02 2012-02-01 Reddys Lab Ltd Dr Niacinformulierungen mit modifizierter freisetzung
WO2010010579A1 (en) * 2008-07-19 2010-01-28 Lupin Limited Multiple unit dosage form of niacin
WO2013052117A1 (en) 2011-10-05 2013-04-11 Golini Jeffrey M Choline composition
US20140113939A1 (en) * 2012-10-22 2014-04-24 Abbott Laboratories Methods for treating hyperlipidemia with intermediate release nicotinic acid compositions having unique biopharmaceutical characteristics

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Also Published As

Publication number Publication date
EP0577504A1 (de) 1994-01-05
EP1688143A3 (de) 2009-11-11
EP1310253A1 (de) 2003-05-14
DE69332463T2 (de) 2003-07-10
DE69332463D1 (de) 2002-12-12
US5268181A (en) 1993-12-07
ES2186674T3 (es) 2003-05-16
EP0577504B1 (de) 2002-11-06
DK0577504T3 (da) 2003-03-17
EP1688143A2 (de) 2006-08-09
PT577504E (pt) 2003-03-31

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