ATE224447T1 - Kainat bindende, menschliche rezeptoren des zentralnervensystems (zns), von der eaa4 (excitatory amino acid) familie - Google Patents
Kainat bindende, menschliche rezeptoren des zentralnervensystems (zns), von der eaa4 (excitatory amino acid) familieInfo
- Publication number
- ATE224447T1 ATE224447T1 AT93304961T AT93304961T ATE224447T1 AT E224447 T1 ATE224447 T1 AT E224447T1 AT 93304961 T AT93304961 T AT 93304961T AT 93304961 T AT93304961 T AT 93304961T AT E224447 T1 ATE224447 T1 AT E224447T1
- Authority
- AT
- Austria
- Prior art keywords
- receptors
- family
- excitatory amino
- eaa4
- cns
- Prior art date
Links
- 230000002461 excitatory amino acid Effects 0.000 title abstract 4
- 239000003257 excitatory amino acid Substances 0.000 title abstract 4
- VLSMHEGGTFMBBZ-OOZYFLPDSA-M Kainate Chemical compound CC(=C)[C@H]1C[NH2+][C@H](C([O-])=O)[C@H]1CC([O-])=O VLSMHEGGTFMBBZ-OOZYFLPDSA-M 0.000 title abstract 2
- 210000003169 central nervous system Anatomy 0.000 title 2
- 102000005962 receptors Human genes 0.000 abstract 6
- 108020003175 receptors Proteins 0.000 abstract 6
- 239000012528 membrane Substances 0.000 abstract 2
- WHUUTDBJXJRKMK-VKHMYHEASA-N L-glutamic acid Chemical compound OC(=O)[C@@H](N)CCC(O)=O WHUUTDBJXJRKMK-VKHMYHEASA-N 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229930195712 glutamate Natural products 0.000 abstract 1
- 230000001404 mediated effect Effects 0.000 abstract 1
- 230000000638 stimulation Effects 0.000 abstract 1
- 230000005062 synaptic transmission Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70571—Receptors; Cell surface antigens; Cell surface determinants for neuromediators, e.g. serotonin receptor, dopamine receptor
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Neurology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Cell Biology (AREA)
- Engineering & Computer Science (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Treatment Of Liquids With Adsorbents In General (AREA)
- Magnetic Resonance Imaging Apparatus (AREA)
- Fluid-Damping Devices (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/903,456 US5574144A (en) | 1992-06-24 | 1992-06-24 | Kainate-binding, human CNS receptors of the EAA4 family |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE224447T1 true ATE224447T1 (de) | 2002-10-15 |
Family
ID=25417534
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT93304961T ATE224447T1 (de) | 1992-06-24 | 1993-06-24 | Kainat bindende, menschliche rezeptoren des zentralnervensystems (zns), von der eaa4 (excitatory amino acid) familie |
Country Status (10)
| Country | Link |
|---|---|
| US (3) | US5574144A (de) |
| EP (1) | EP0578409B1 (de) |
| JP (1) | JPH06189767A (de) |
| AT (1) | ATE224447T1 (de) |
| CA (1) | CA2099072A1 (de) |
| DE (1) | DE69332299T2 (de) |
| DK (1) | DK0578409T3 (de) |
| ES (1) | ES2183809T3 (de) |
| MX (1) | MX9303769A (de) |
| PT (1) | PT578409E (de) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE69434333T2 (de) * | 1993-12-23 | 2006-03-09 | Nps Allelix Corp., Mississauga | Methoden unter verwendung von eaa3 oder eaa4 rezeptoren |
| GB2316616A (en) * | 1996-09-02 | 1998-03-04 | Lilly Industries Ltd | Modulation of GluR5 receptors in the hippocampus to treat psychiatric disorders |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1991006648A1 (en) * | 1989-10-27 | 1991-05-16 | The Salk Institute For Biological Studies | Glutamate receptor compositions and methods |
| PT529994E (pt) * | 1991-08-26 | 2000-10-31 | Nps Allelix Corp | Receptor de ka-1 humano um receptor de cainato de elevada afinidade da familia eaa1 (aminoacido excitatorio) |
| DE69230872T2 (de) * | 1991-08-27 | 2000-10-26 | Allelix Biopharmaceuticals Inc., Mississauga | Menschlicher KA-2-Rezeptor, Rezeptor aus der EAA2-Familie (Excitatory Amino Acid) mit hoher Affinität für Kainat |
-
1992
- 1992-06-24 US US07/903,456 patent/US5574144A/en not_active Expired - Lifetime
-
1993
- 1993-06-23 CA CA002099072A patent/CA2099072A1/en not_active Abandoned
- 1993-06-23 MX MX9303769A patent/MX9303769A/es unknown
- 1993-06-24 DE DE69332299T patent/DE69332299T2/de not_active Expired - Fee Related
- 1993-06-24 AT AT93304961T patent/ATE224447T1/de not_active IP Right Cessation
- 1993-06-24 PT PT93304961T patent/PT578409E/pt unknown
- 1993-06-24 DK DK93304961T patent/DK0578409T3/da active
- 1993-06-24 JP JP5177327A patent/JPH06189767A/ja active Pending
- 1993-06-24 EP EP93304961A patent/EP0578409B1/de not_active Expired - Lifetime
- 1993-06-24 ES ES93304961T patent/ES2183809T3/es not_active Expired - Lifetime
-
1994
- 1994-05-25 US US08/249,241 patent/US6376200B1/en not_active Expired - Fee Related
-
2002
- 2002-04-22 US US10/126,617 patent/US20020168723A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| DE69332299T2 (de) | 2003-05-08 |
| CA2099072A1 (en) | 1993-12-25 |
| PT578409E (pt) | 2003-02-28 |
| US5574144A (en) | 1996-11-12 |
| JPH06189767A (ja) | 1994-07-12 |
| US6376200B1 (en) | 2002-04-23 |
| EP0578409A2 (de) | 1994-01-12 |
| US20020168723A1 (en) | 2002-11-14 |
| ES2183809T3 (es) | 2003-04-01 |
| EP0578409A3 (de) | 1994-11-23 |
| EP0578409B1 (de) | 2002-09-18 |
| DE69332299D1 (de) | 2002-10-24 |
| DK0578409T3 (da) | 2003-01-27 |
| MX9303769A (es) | 1994-05-31 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 0578409 Country of ref document: EP |
|
| EEFA | Change of the company name | ||
| EEIH | Change in the person of patent owner | ||
| REN | Ceased due to non-payment of the annual fee |