ATE221385T1 - Zyklisches heptapeptid als entzündungshemmendes agens - Google Patents

Zyklisches heptapeptid als entzündungshemmendes agens

Info

Publication number
ATE221385T1
ATE221385T1 AT95911020T AT95911020T ATE221385T1 AT E221385 T1 ATE221385 T1 AT E221385T1 AT 95911020 T AT95911020 T AT 95911020T AT 95911020 T AT95911020 T AT 95911020T AT E221385 T1 ATE221385 T1 AT E221385T1
Authority
AT
Austria
Prior art keywords
cyclomarin
inflammatory agent
cyclic heptapeptide
isolated
bacterium
Prior art date
Application number
AT95911020T
Other languages
English (en)
Inventor
William H Fenical
Robert S Jacobs
Paul R Jensen
Original Assignee
Univ California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ California filed Critical Univ California
Application granted granted Critical
Publication of ATE221385T1 publication Critical patent/ATE221385T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64—Cyclic peptides containing only normal peptide links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Communicable Diseases (AREA)
  • Hematology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Obesity (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AT95911020T 1994-02-18 1995-02-16 Zyklisches heptapeptid als entzündungshemmendes agens ATE221385T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/198,859 US5444043A (en) 1994-02-18 1994-02-18 Cyclic heptapeptide anti-inflammatory agent
PCT/US1995/001970 WO1995022339A1 (en) 1994-02-18 1995-02-16 Cyclic heptapeptide anti-inflammatory agent

Publications (1)

Publication Number Publication Date
ATE221385T1 true ATE221385T1 (de) 2002-08-15

Family

ID=22735156

Family Applications (1)

Application Number Title Priority Date Filing Date
AT95911020T ATE221385T1 (de) 1994-02-18 1995-02-16 Zyklisches heptapeptid als entzündungshemmendes agens

Country Status (15)

Country Link
US (2) US5444043A (de)
EP (1) EP0744955B1 (de)
JP (1) JPH09509318A (de)
KR (1) KR100349485B1 (de)
AT (1) ATE221385T1 (de)
AU (1) AU696517B2 (de)
BR (1) BR9506866A (de)
CA (1) CA2181827A1 (de)
CZ (1) CZ231896A3 (de)
DE (1) DE69527610D1 (de)
FI (1) FI963194A (de)
HU (1) HU221122B1 (de)
NO (1) NO963418L (de)
NZ (1) NZ281823A (de)
WO (1) WO1995022339A1 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5444043A (en) * 1994-02-18 1995-08-22 The Regents Of The University Of California Cyclic heptapeptide anti-inflammatory agent
US5759995A (en) * 1996-09-05 1998-06-02 Phytera, Inc. Antiviral treatment
AU2002322720B2 (en) 2001-07-25 2008-11-13 Raptor Pharmaceutical Inc. Compositions and methods for modulating blood-brain barrier transport
WO2006116718A2 (en) 2005-04-28 2006-11-02 Proteus Biomedical, Inc. Pharma-informatics system
WO2006119174A1 (en) 2005-04-30 2006-11-09 Ocular Surface Center, P.A. Method for treating ocular demodex
JP2010503710A (ja) 2006-09-18 2010-02-04 ラプトール ファーマシューティカル インコーポレイテッド 受容体関連タンパク質（ｒａｐ）結合体の投与による肝障害の処置
US8128968B2 (en) 2007-08-29 2012-03-06 Tissuetech, Inc. Compositions and methods for treating Demodex infestations
ES2919563T3 (es) 2009-02-20 2022-07-27 Enhanx Biopharm Inc Sistema de administración de medicamentos a base de glutatión
EA024559B1 (ru) 2009-05-06 2016-09-30 Лаборэтори Скин Кэа, Инк. Композиции для нанесения на кератинизированную поверхность кожи млекопитающего и способ доставки
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates
US20230190950A1 (en) * 2017-01-06 2023-06-22 Cidara Therapeutics, Inc. Compositions and methods for the treatment of bacterial infections
WO2019126353A2 (en) * 2017-12-20 2019-06-27 Cidara Therapeutics, Inc. Compositions and methods for the treatment of bacterial infections
CN111647050B (zh) * 2020-05-13 2021-11-09 中国科学院南海海洋研究所 一种怡莱霉素f衍生物及其在制备抗结核分枝杆菌药物中的应用

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4331594A (en) * 1978-10-16 1982-05-25 Eli Lilly And Company A-21978 Antibiotics and process for their production
USRE32455E (en) * 1978-10-16 1987-07-07 Eli Lilly And Company A-21978 antibiotics and process for their production
CA1172980A (en) * 1979-04-02 1984-08-21 Kenji Takemoto Pentadecapeptide and process for the preparation thereof
US4950649A (en) * 1980-09-12 1990-08-21 University Of Illinois Didemnins and nordidemnins
US4342829A (en) * 1981-05-06 1982-08-03 Eli Lilly And Company Process for preparing narasin
US4384043A (en) * 1981-09-02 1983-05-17 American Cyanamid Company Process for producing the antibiotic nosiheptide
US4409210A (en) * 1982-01-15 1983-10-11 Bristol-Myers Company Antibiotic compound
US4677071A (en) * 1982-03-25 1987-06-30 American Cyanamid Company Antibiotic agents from S. coeruleorubidus, rubidus
US4608343A (en) * 1983-06-23 1986-08-26 American Cyanamid Company Biologically pure culture of Streptomyces majorciensis Labeda
US4582639A (en) * 1984-06-18 1986-04-15 Bristol-Myers Company Antitumor antibiotic compound
US4885243A (en) * 1984-10-09 1989-12-05 Eli Lilly And Company Process for producing A-21978C derivatives
US5006466A (en) * 1986-11-21 1991-04-09 Merck & Co., Inc. Fermentation analogs of virginiamycin M1
US5229362A (en) * 1986-12-15 1993-07-20 Eli Lilly And Company Antibiotic A10255 complex and factors, and process and production therefor
US5217952A (en) * 1988-02-02 1993-06-08 Fujisawa Pharmaceutical Co., Ltd. Peptides WS-9326a and WS-9326b, derivatives thereof and uses thereof
US4977083A (en) * 1988-04-11 1990-12-11 Eli Lilly And Company Processes for preparing A54145 compounds
US5028590A (en) * 1988-04-11 1991-07-02 Eli Lilly And Company Derivatives of A54145 cyclic peptides
US5138036A (en) * 1989-11-13 1992-08-11 Arizona Board Of Regents Acting On Behalf Of Arizona State University Isolation and structural elucidation of the cytostatic cyclodepsipeptide dolastatin 14
US5336757A (en) * 1992-02-07 1994-08-09 Harbor Branch Oceanographic Institution, Inc. Antibacterial peptide and methods of use
US5444043A (en) * 1994-02-18 1995-08-22 The Regents Of The University Of California Cyclic heptapeptide anti-inflammatory agent

Also Published As

Publication number Publication date
HU9602252D0 (en) 1996-10-28
HU221122B1 (en) 2002-08-28
HUT75832A (en) 1997-05-28
NO963418L (no) 1996-08-15
JPH09509318A (ja) 1997-09-22
CA2181827A1 (en) 1995-08-24
FI963194A (fi) 1996-09-23
AU1877395A (en) 1995-09-04
AU696517B2 (en) 1998-09-10
EP0744955A1 (de) 1996-12-04
CZ231896A3 (en) 1997-01-15
US5593960A (en) 1997-01-14
KR100349485B1 (ko) 2002-11-18
FI963194A0 (fi) 1996-08-15
EP0744955B1 (de) 2002-07-31
BR9506866A (pt) 1997-09-09
EP0744955A4 (de) 1998-12-16
WO1995022339A1 (en) 1995-08-24
NZ281823A (en) 1997-11-24
US5444043A (en) 1995-08-22
DE69527610D1 (de) 2002-09-05

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