ATE219675T1 - Pharmazeutische zubereitung zur behandlung sogenannter rastloser beine - Google Patents
Pharmazeutische zubereitung zur behandlung sogenannter rastloser beineInfo
- Publication number
- ATE219675T1 ATE219675T1 AT98902380T AT98902380T ATE219675T1 AT E219675 T1 ATE219675 T1 AT E219675T1 AT 98902380 T AT98902380 T AT 98902380T AT 98902380 T AT98902380 T AT 98902380T AT E219675 T1 ATE219675 T1 AT E219675T1
- Authority
- AT
- Austria
- Prior art keywords
- treatment
- restless legs
- quinine
- pharmaceutically acceptable
- group
- Prior art date
Links
- 208000005793 Restless legs syndrome Diseases 0.000 title abstract 4
- 239000000825 pharmaceutical preparation Substances 0.000 title 1
- LOUPRKONTZGTKE-WZBLMQSHSA-N Quinine Chemical compound C([C@H]([C@H](C1)C=C)C2)C[N@@]1[C@@H]2[C@H](O)C1=CC=NC2=CC=C(OC)C=C21 LOUPRKONTZGTKE-WZBLMQSHSA-N 0.000 abstract 6
- 150000001875 compounds Chemical class 0.000 abstract 4
- 235000001258 Cinchona calisaya Nutrition 0.000 abstract 3
- LOUPRKONTZGTKE-UHFFFAOYSA-N cinchonine Natural products C1C(C(C2)C=C)CCN2C1C(O)C1=CC=NC2=CC=C(OC)C=C21 LOUPRKONTZGTKE-UHFFFAOYSA-N 0.000 abstract 3
- 229910052739 hydrogen Inorganic materials 0.000 abstract 3
- 239000001257 hydrogen Substances 0.000 abstract 3
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 3
- 229960000948 quinine Drugs 0.000 abstract 3
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000004432 carbon atom Chemical group C* 0.000 abstract 2
- 125000005843 halogen group Chemical group 0.000 abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 239000000126 substance Substances 0.000 abstract 2
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 229910052801 chlorine Inorganic materials 0.000 abstract 1
- 239000000460 chlorine Substances 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 238000011287 therapeutic dose Methods 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/49—Cinchonan derivatives, e.g. quinine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE9700803A SE509618C2 (sv) | 1997-03-06 | 1997-03-06 | Farmaceutisk komposition för behandling av s k restless legs |
| PCT/SE1998/000199 WO1998039005A1 (en) | 1997-03-06 | 1998-02-03 | Pharmaceutical composition for the treatment of so-called restless legs |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE219675T1 true ATE219675T1 (de) | 2002-07-15 |
Family
ID=20406044
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT98902380T ATE219675T1 (de) | 1997-03-06 | 1998-02-03 | Pharmazeutische zubereitung zur behandlung sogenannter rastloser beine |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US6214837B1 (de) |
| EP (1) | EP1003517B1 (de) |
| AT (1) | ATE219675T1 (de) |
| AU (1) | AU5893398A (de) |
| DE (1) | DE69806248T2 (de) |
| SE (1) | SE509618C2 (de) |
| WO (1) | WO1998039005A1 (de) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2003262860A1 (en) | 2002-08-30 | 2004-03-19 | Kyowa Hakko Kogyo Co., Ltd. | Adenosine a2a receptor antagonists for treating restless legs syndrome or related disorders |
| SG146643A1 (en) | 2003-09-17 | 2008-10-30 | Xenoport Inc | Treating or preventing restless legs syndrome using prodrugs of gaba analogs |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3014911A (en) | 1958-09-29 | 1961-12-26 | Merck & Co Inc | Derivatives of dibenzo[a, e]cycloheptatriene |
| US4282233B1 (en) | 1980-06-19 | 2000-09-05 | Schering Corp | Antihistaminic 11-(4-piperidylidene)-5h-benzoÄ5,6Ü-cyclohepta-Ä1,2Ü-pyridines |
| US5759198A (en) * | 1995-12-05 | 1998-06-02 | Karell; Manuel L. | Method and apparatus for treating and preventing leg cramps and other muscle contractions and sleep disorders |
| US6100274A (en) * | 1999-07-07 | 2000-08-08 | Schering Corporation | 8-chloro-6,11-dihydro-11- ](4-piperidylidine)-5H-benzo[5,6]cyclohepta[1,2-bpyridine oral compositions |
-
1997
- 1997-03-06 SE SE9700803A patent/SE509618C2/sv not_active IP Right Cessation
-
1998
- 1998-02-03 AT AT98902380T patent/ATE219675T1/de active
- 1998-02-03 EP EP98902380A patent/EP1003517B1/de not_active Expired - Lifetime
- 1998-02-03 AU AU58933/98A patent/AU5893398A/en not_active Abandoned
- 1998-02-03 WO PCT/SE1998/000199 patent/WO1998039005A1/en not_active Ceased
- 1998-02-03 DE DE69806248T patent/DE69806248T2/de not_active Expired - Lifetime
- 1998-02-03 US US09/380,295 patent/US6214837B1/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| SE9700803D0 (sv) | 1997-03-06 |
| EP1003517A1 (de) | 2000-05-31 |
| WO1998039005A1 (en) | 1998-09-11 |
| SE9700803L (sv) | 1998-09-07 |
| DE69806248T2 (de) | 2002-11-07 |
| AU5893398A (en) | 1998-09-22 |
| DE69806248D1 (de) | 2002-08-01 |
| SE509618C2 (sv) | 1999-02-15 |
| EP1003517B1 (de) | 2002-06-26 |
| US6214837B1 (en) | 2001-04-10 |
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