ATE210992T1 - Injizierbare zusammensetzungen zur vergrösserung von weichgewebe - Google Patents

Injizierbare zusammensetzungen zur vergrösserung von weichgewebe

Info

Publication number
ATE210992T1
ATE210992T1 AT94927397T AT94927397T ATE210992T1 AT E210992 T1 ATE210992 T1 AT E210992T1 AT 94927397 T AT94927397 T AT 94927397T AT 94927397 T AT94927397 T AT 94927397T AT E210992 T1 ATE210992 T1 AT E210992T1
Authority
AT
Austria
Prior art keywords
soft tissue
injectable compositions
tissue augmentation
injectable implant
enlarging
Prior art date
Application number
AT94927397T
Other languages
English (en)
Inventor
Ernst Janzen
Matthias Johannes Hoekstra
Richard P Dutrieux
Original Assignee
Datascope Investment Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Datascope Investment Corp filed Critical Datascope Investment Corp
Application granted granted Critical
Publication of ATE210992T1 publication Critical patent/ATE210992T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3683Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix subjected to a specific treatment prior to implantation, e.g. decellularising, demineralising, grinding, cellular disruption/non-collagenous protein removal, anti-calcification, crosslinking, supercritical fluid extraction, enzyme treatment
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/39Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14Macromolecular materials
    • A61L27/22Polypeptides or derivatives thereof, e.g. degradation products
    • A61L27/227Other specific proteins or polypeptides not covered by A61L27/222, A61L27/225 or A61L27/24
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14Macromolecular materials
    • A61L27/26Mixtures of macromolecular compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/36Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix
    • A61L27/3641Materials for grafts or prostheses or for coating grafts or prostheses containing ingredients of undetermined constitution or reaction products thereof, e.g. transplant tissue, natural bone, extracellular matrix characterised by the site of application in the body
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Botany (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Vascular Medicine (AREA)
  • Organic Chemistry (AREA)
  • Surgery (AREA)
  • Materials For Medical Uses (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Prostheses (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
AT94927397T 1993-09-07 1994-09-07 Injizierbare zusammensetzungen zur vergrösserung von weichgewebe ATE210992T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/116,517 US5523291A (en) 1993-09-07 1993-09-07 Injectable compositions for soft tissue augmentation
PCT/US1994/010223 WO1995007095A1 (en) 1993-09-07 1994-09-07 Injectable compositions for soft tissue augmentation

Publications (1)

Publication Number Publication Date
ATE210992T1 true ATE210992T1 (de) 2002-01-15

Family

ID=22367654

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94927397T ATE210992T1 (de) 1993-09-07 1994-09-07 Injizierbare zusammensetzungen zur vergrösserung von weichgewebe

Country Status (13)

Country Link
US (2) US5523291A (de)
EP (1) EP0717634B1 (de)
KR (1) KR100333088B1 (de)
CN (1) CN1142789C (de)
AT (1) ATE210992T1 (de)
AU (1) AU675879B2 (de)
BR (1) BR9407420A (de)
CA (1) CA2170754C (de)
DE (1) DE69429522T2 (de)
DK (1) DK0717634T3 (de)
ES (1) ES2169085T3 (de)
PT (1) PT717634E (de)
WO (1) WO1995007095A1 (de)

Families Citing this family (65)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5606019A (en) * 1987-10-29 1997-02-25 Protien Polymer Technologies, Inc. Synthetic protein as implantables
US7060287B1 (en) 1992-02-11 2006-06-13 Bioform Inc. Tissue augmentation material and method
US7968110B2 (en) * 1992-02-11 2011-06-28 Merz Aesthetics, Inc. Tissue augmentation material and method
US6537574B1 (en) 1992-02-11 2003-03-25 Bioform, Inc. Soft tissue augmentation material
US5676698A (en) * 1993-09-07 1997-10-14 Datascope Investment Corp. Soft tissue implant
US5523291A (en) * 1993-09-07 1996-06-04 Datascope Investment Corp. Injectable compositions for soft tissue augmentation
US6334872B1 (en) * 1994-02-18 2002-01-01 Organogenesis Inc. Method for treating diseased or damaged organs
US20020095218A1 (en) * 1996-03-12 2002-07-18 Carr Robert M. Tissue repair fabric
US5993844A (en) * 1997-05-08 1999-11-30 Organogenesis, Inc. Chemical treatment, without detergents or enzymes, of tissue to form an acellular, collagenous matrix
US6371992B1 (en) * 1997-12-19 2002-04-16 The Regents Of The University Of California Acellular matrix grafts: preparation and use
US6069129A (en) * 1998-03-13 2000-05-30 Mrs, Llc Elastin derived composition and method of using same
US6809075B1 (en) 2000-05-30 2004-10-26 Connective Tissue Imagineering Llc Elastin peptide analogs and uses of same incombination with skin enhancing agents
US6962904B1 (en) 1998-03-13 2005-11-08 Connective Tissue Imagineering Elastin peptide analogs and uses thereof
DE69940507D1 (de) * 1998-06-05 2009-04-16 Organogenesis Inc Biotechnisch erzeugte gefässprothese für die implantation
WO1999062427A1 (en) * 1998-06-05 1999-12-09 Organogenesis Inc. Bioengineered vascular graft support prostheses
JP4341049B2 (ja) * 1998-06-05 2009-10-07 オルガノジェネシス インク. 生物工学により作成したチューブ状移植片補綴
EP1082071B1 (de) * 1998-06-05 2009-03-04 Organogenesis Inc. Verfahren zur herstellung einer gefässprothese
GB2345638A (en) * 1998-09-11 2000-07-19 Tissue Science Lab Limited Injectable collagen compositions
US6777389B1 (en) 1998-11-19 2004-08-17 Connective Tissue Imagineering Llc Cosmetic or dermatological use of 7-hydroxylated steroids in combination with elastin derived peptides
US6572532B1 (en) * 1999-03-01 2003-06-03 Advanced Biomedical Devices Inc. Implant positioning system and method
US6866686B2 (en) * 2000-01-28 2005-03-15 Cryolife, Inc. Tissue graft
US6794362B1 (en) 2000-05-30 2004-09-21 Connective Tissue Imagineering Llc Asparagine containing elastin peptide analogs
MXPA03002414A (es) * 2000-09-18 2004-07-08 Organogenesis Inc Protesis con injerto de hoja plana tratada por bioingenieria y su uso.
KR100514582B1 (ko) * 2001-09-05 2005-09-13 한스바이오메드 주식회사 생체복원물질의 제조방법
US20030181371A1 (en) * 2001-12-28 2003-09-25 Angiotech Pharmaceuticals, Inc. Compositions and methods of using collajolie
US7064187B2 (en) 2002-11-26 2006-06-20 Crosscart, Inc. Substantially non-immunogenic injectable collagen
BR0317715A (pt) * 2002-12-27 2005-11-22 Angiotech Int Ag Composições e processos de uso de collajolie
US8137688B2 (en) * 2003-01-10 2012-03-20 The Cleveland Clinic Foundation Hydroxyphenyl cross-linked macromolecular network and applications thereof
US7465766B2 (en) * 2004-01-08 2008-12-16 The Cleveland Clinic Foundation Hydroxyphenyl cross-linked macromolecular network and applications thereof
US8138265B2 (en) * 2003-01-10 2012-03-20 The Cleveland Clinic Foundation Hydroxyphenyl cross-linked macromolecular network and applications thereof
FR2850282B1 (fr) * 2003-01-27 2007-04-06 Jerome Asius Implant injectable a base de ceramique pour le comblement de rides, depressions cutanees et cicatrices, et sa preparation
EP1516636A3 (de) * 2003-09-19 2005-08-03 Broockeville Corporation N.V. Verwendung eines härtbaren Elastomer-Precusors in einer medizinischen Behandlung
US7597660B2 (en) * 2003-09-19 2009-10-06 Broockeville Corporation B.V. Incontinence therapy
AU2004289287A1 (en) * 2003-11-10 2005-05-26 Angiotech International Ag Medical implants and fibrosis-inducing agents
US8124120B2 (en) * 2003-12-22 2012-02-28 Anika Therapeutics, Inc. Crosslinked hyaluronic acid compositions for tissue augmentation
US20050209695A1 (en) * 2004-03-15 2005-09-22 De Vries Jan A Vertebroplasty method
US20050228216A1 (en) * 2004-04-08 2005-10-13 Vries Jan A D Method for treating gastroesophageal reflux disease
CN1294994C (zh) * 2004-07-05 2007-01-17 暨南大学 可注射型胶原基软组织填充材料及其制备方法
US9788821B2 (en) * 2005-04-29 2017-10-17 Cook Biotech Incorporated Physically modified extracellular matrix materials and uses thereof
AU2006265601A1 (en) * 2005-06-30 2007-01-11 Anthrogenesis Corporation Repair of tympanic membrane using placenta derived collagen biofabric
US20070184087A1 (en) * 2006-02-06 2007-08-09 Bioform Medical, Inc. Polysaccharide compositions for use in tissue augmentation
WO2008021391A1 (en) * 2006-08-15 2008-02-21 Anthrogenesis Corporation Umbilical cord biomaterial for medical use
GB0618215D0 (en) * 2006-09-15 2006-10-25 Novathera Ltd Composite material
WO2008042441A1 (en) * 2006-10-03 2008-04-10 Anthrogenesis Corporation Use of umbilical cord biomaterial for ocular surgery
US8071135B2 (en) 2006-10-04 2011-12-06 Anthrogenesis Corporation Placental tissue compositions
AU2007318210B2 (en) 2006-10-06 2014-02-20 Celularity Inc. Native (telopeptide) placental collagen compositions
CA2669114C (en) 2006-11-13 2014-12-16 The University Of Sydney Use of tropoelastin for repair or restoration of tissue
US9056151B2 (en) * 2007-02-12 2015-06-16 Warsaw Orthopedic, Inc. Methods for collagen processing and products using processed collagen
US20080260794A1 (en) * 2007-02-12 2008-10-23 Lauritzen Nels J Collagen products and methods for producing collagen products
CA2684012A1 (en) * 2007-04-16 2008-10-23 Tissue Science Laboratories Plc Vascular implant
EP2178576A2 (de) * 2007-04-16 2010-04-28 Tissue Science Laboratories PLC Knochenimplantat
EP2182971B1 (de) * 2007-07-27 2013-12-18 Humacyte, Inc. Zusammensetzungen menschliches Kollagen und menschliches Elastin enthaltend und deren Anwendungen
US8080260B2 (en) * 2008-02-13 2011-12-20 The Cleveland Clinic Foundation Molecular enhancement of extracellular matrix and methods of use
KR100947553B1 (ko) * 2008-02-14 2010-03-12 주식회사 바이오랜드 생체조직 이식재 및 그의 제조 방법
EP2300042A4 (de) * 2008-04-30 2012-05-02 Cleveland Clinic Foundation Zusammensetzungen und verfahren zur behandlung von harninkontinenz
JP2011525140A (ja) * 2008-06-20 2011-09-15 クック・バイオテック・インコーポレイテッド 複合細胞外マトリックス材料およびそれらから形成される医療製品
WO2010053918A1 (en) * 2008-11-05 2010-05-14 Hancock Jaffe Laboratories, Inc. Composite containing collagen and elastin as a dermal expander and tissue filler
US20110020271A1 (en) * 2009-05-20 2011-01-27 Humacyte, Inc. Elastin for soft tissue augmentation
US8252022B2 (en) * 2009-07-13 2012-08-28 Vascular Solutions, Inc. Metal vascular aperture closure device
US8460691B2 (en) 2010-04-23 2013-06-11 Warsaw Orthopedic, Inc. Fenestrated wound repair scaffold
US8790699B2 (en) 2010-04-23 2014-07-29 Warsaw Orthpedic, Inc. Foam-formed collagen strand
US20130011451A1 (en) 2011-07-06 2013-01-10 Diversified Glogal Technologies, Llc Footbed with non-denatured collagen
EP3104865A4 (de) * 2014-02-11 2017-11-22 Anthrogenesis Corporation Mikro-organoide und verfahren zur herstellung und verwendung davon
US9993578B1 (en) * 2017-01-12 2018-06-12 Lorstan Pharmaceutical, LLC Silicone oil-in-water composition useful as an injectable filler and as a scaffold for collagen growth
CA3099139A1 (en) 2018-05-03 2019-11-07 Collplant Ltd. Dermal fillers and applications thereof

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4233360A (en) * 1975-10-22 1980-11-11 Collagen Corporation Non-antigenic collagen and articles of manufacture
US4488911A (en) * 1975-10-22 1984-12-18 Luck Edward E Non-antigenic collagen and articles of manufacture
CA1073360A (en) * 1975-10-22 1980-03-11 John R. Daniels Non-antigenic collagen and articles of manufacture
DE2705670C3 (de) * 1977-02-11 1983-11-17 Fa. Carl Freudenberg, 6940 Weinheim Verfahren zur Herstellung von wasserlöslichen Elastin-Hydrolysaten
CA1190855A (en) * 1980-09-03 1985-07-23 Rolf W. Pfirrmann Treatment of osteitis
US4378224A (en) * 1980-09-19 1983-03-29 Nimni Marcel E Coating for bioprosthetic device and method of making same
US4424208A (en) * 1982-01-11 1984-01-03 Collagen Corporation Collagen implant material and method for augmenting soft tissue
US4960423A (en) * 1982-11-17 1990-10-02 Smith Donald W Method of enhancing the attachment of endothelial cells on a matrix and vascular prosthesis with enhanced anti-thrombogenic characteristics
US4692552A (en) * 1983-05-09 1987-09-08 G. D. Searle & Co. Protease inhibitors
US4801299A (en) * 1983-06-10 1989-01-31 University Patents, Inc. Body implants of extracellular matrix and means and methods of making and using such implants
US4601896A (en) * 1984-03-21 1986-07-22 Mark Nugent Pharmaceutical capsule compositions and structures for gastric sensitive materials
US4837285A (en) * 1984-03-27 1989-06-06 Medimatrix Collagen matrix beads for soft tissue repair
US4642117A (en) * 1985-03-22 1987-02-10 Collagen Corporation Mechanically sheared collagen implant material and method
US4649147A (en) * 1985-07-08 1987-03-10 G. D. Searle & Co. Treating elastin degradation with 1-(alkenoyl)azacycloalkyl carboxylic acids and derivatives
US4803075A (en) * 1986-06-25 1989-02-07 Collagen Corporation Injectable implant composition having improved intrudability
GB8618374D0 (en) * 1986-07-28 1986-09-03 Hsc Res Dev Corp Biological vascular prostheses
GB8708009D0 (en) * 1987-04-03 1987-05-07 Clayton Found Res Injectable soft tissue augmentation materials
ES2060614T3 (es) * 1988-03-11 1994-12-01 Chemokol G B R Ing Buro Fur Ko Procedimiento para la fabricacion de membranas de colageno para hemostasis, tratamiento de heridas e implantes.
US5024841A (en) * 1988-06-30 1991-06-18 Collagen Corporation Collagen wound healing matrices and process for their production
US5110604A (en) * 1988-06-30 1992-05-05 Collagen Corporation Processes for producing collagen matrixes and methods of using same
US4950483A (en) * 1988-06-30 1990-08-21 Collagen Corporation Collagen wound healing matrices and process for their production
US5138030A (en) * 1989-10-10 1992-08-11 Pachence James M Process for extracting type I collagen form an avian source, and applications therefor
US5206028A (en) * 1991-02-11 1993-04-27 Li Shu Tung Dense collagen membrane matrices for medical uses
US5204382A (en) * 1992-02-28 1993-04-20 Collagen Corporation Injectable ceramic compositions and methods for their preparation and use
US5523291A (en) * 1993-09-07 1996-06-04 Datascope Investment Corp. Injectable compositions for soft tissue augmentation

Also Published As

Publication number Publication date
BR9407420A (pt) 1996-11-12
US5523291A (en) 1996-06-04
CA2170754C (en) 2006-07-11
CN1142789C (zh) 2004-03-24
DE69429522T2 (de) 2002-08-01
KR960704562A (ko) 1996-10-09
PT717634E (pt) 2002-06-28
US5705488A (en) 1998-01-06
ES2169085T3 (es) 2002-07-01
DK0717634T3 (da) 2002-04-15
EP0717634A4 (de) 1999-03-17
AU7685794A (en) 1995-03-27
DE69429522D1 (de) 2002-01-31
CN1133562A (zh) 1996-10-16
CA2170754A1 (en) 1995-03-16
EP0717634B1 (de) 2001-12-19
EP0717634A1 (de) 1996-06-26
WO1995007095A1 (en) 1995-03-16
JPH09502372A (ja) 1997-03-11
KR100333088B1 (ko) 2002-09-12
JP3596892B2 (ja) 2004-12-02
AU675879B2 (en) 1997-02-20

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