ATE209044T1 - Eine stabilisierte phenylalanin-ammonia-lyase - Google Patents

Eine stabilisierte phenylalanin-ammonia-lyase

Info

Publication number
ATE209044T1
ATE209044T1 AT94919559T AT94919559T ATE209044T1 AT E209044 T1 ATE209044 T1 AT E209044T1 AT 94919559 T AT94919559 T AT 94919559T AT 94919559 T AT94919559 T AT 94919559T AT E209044 T1 ATE209044 T1 AT E209044T1
Authority
AT
Austria
Prior art keywords
ammonia lyase
phenylalanine ammonia
pct
stabilized
sec
Prior art date
Application number
AT94919559T
Other languages
German (de)
English (en)
Inventor
Peter Eigtved
Ib Groth Clausen
Original Assignee
Novozymes As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novozymes As filed Critical Novozymes As
Application granted granted Critical
Publication of ATE209044T1 publication Critical patent/ATE209044T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Detergent Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Lubricants (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Medicinal Preparation (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT94919559T 1993-06-25 1994-06-09 Eine stabilisierte phenylalanin-ammonia-lyase ATE209044T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DK93755A DK75593D0 (enExample) 1993-06-25 1993-06-25
PCT/DK1994/000224 WO1995000171A1 (en) 1993-06-25 1994-06-09 A stabilised phenylalanine ammonia lyase

Publications (1)

Publication Number Publication Date
ATE209044T1 true ATE209044T1 (de) 2001-12-15

Family

ID=8097168

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94919559T ATE209044T1 (de) 1993-06-25 1994-06-09 Eine stabilisierte phenylalanin-ammonia-lyase

Country Status (10)

Country Link
US (1) US5753487A (enExample)
EP (1) EP0703788B1 (enExample)
AT (1) ATE209044T1 (enExample)
AU (1) AU7067594A (enExample)
CA (1) CA2165281A1 (enExample)
DE (1) DE69429167T2 (enExample)
DK (2) DK75593D0 (enExample)
ES (1) ES2168297T3 (enExample)
PT (1) PT703788E (enExample)
WO (1) WO1995000171A1 (enExample)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6051020A (en) 1994-02-09 2000-04-18 Boston Scientific Technology, Inc. Bifurcated endoluminal prosthesis
DE69633127T2 (de) 1995-09-29 2005-08-04 BioMarin Pharmaceutical, Inc., Novato Verwendung von heparinasen zur verminderung von entzündungsreaktionen
US5647368A (en) * 1996-02-28 1997-07-15 Xillix Technologies Corp. Imaging system for detecting diseased tissue using native fluorsecence in the gastrointestinal and respiratory tract
US6190883B1 (en) 1998-09-09 2001-02-20 Novo Nordisk A/S Method for the production of heterologous polypeptides in transformed yeast cells
US6368837B1 (en) 1999-08-06 2002-04-09 E. I. Du Pont Nemours And Company Bioproduction of para-hydroxycinnamic acid
US6521748B2 (en) * 1999-08-06 2003-02-18 E. I. Du Pont De Nemours And Company Polynucleotide encoding a mutant Rhodotorula glutinis tyrosine ammonia lyase polypeptide
EP1372703A2 (en) * 2001-02-16 2004-01-02 Ibex Technologies Matrix stabilized enzyme crystals and methods of use
US7553653B2 (en) * 2004-09-17 2009-06-30 Biomarin Pharmaceutical Inc. Variants and chemically-modified variants of phenylalanine ammonia-lyase
EP2886658A1 (en) 2005-03-10 2015-06-24 BASF Enzymes LLC Lyase enzymes, nucleic acids encoding them and methods for making and using them
US20070122344A1 (en) 2005-09-02 2007-05-31 University Of Rochester Medical Center Office Of Technology Transfer Intraoperative determination of nerve location
US7531341B1 (en) 2006-06-12 2009-05-12 Biomarin Pharmaceutical Inc. Compositions of prokaryotic phenylalanine ammonia-lyase and methods of using compositions thereof
US7534595B2 (en) 2006-06-12 2009-05-19 Biomarin Pharmaceutical Inc. Compositions of prokaryotic phenylalanine ammonia-lyase and methods of using compositions thereof
US20080161744A1 (en) 2006-09-07 2008-07-03 University Of Rochester Medical Center Pre-And Intra-Operative Localization of Penile Sentinel Nodes
US7560263B2 (en) * 2007-08-17 2009-07-14 Biomarin Pharmaceutical Inc. Compositions of prokaryotic phenylalanine ammonia-lyase and methods of treating cancer using compositions thereof
US8406860B2 (en) 2008-01-25 2013-03-26 Novadaq Technologies Inc. Method for evaluating blush in myocardial tissue
US10219742B2 (en) 2008-04-14 2019-03-05 Novadaq Technologies ULC Locating and analyzing perforator flaps for plastic and reconstructive surgery
EP3372250B1 (en) 2008-05-02 2019-12-25 Novadaq Technologies ULC Methods for production and use of substance-loaded erythrocytes for observation and treatment of microvascular hemodynamics
US9376659B2 (en) 2008-07-24 2016-06-28 Arch Personal Care Products, L.P. Personal care composition containing yeast/polyphenol ferment extract
WO2010014225A2 (en) 2008-07-30 2010-02-04 Biomarin Pharmaceutical Inc. Assays for detection of phenylalanine ammonia-lyase and antibodies to phenylalanine ammonia-lyase
US10492671B2 (en) 2009-05-08 2019-12-03 Novadaq Technologies ULC Near infra red fluorescence imaging for visualization of blood vessels during endoscopic harvest
SI3025728T1 (sl) 2010-02-04 2018-11-30 Biomarin Pharmaceutical Inc. Metoda za čiščenje prokariontskih fenilalanin amonij-liaznih variant
US8354262B2 (en) 2010-06-30 2013-01-15 Codexis, Inc. Chemically modified carbonic anhydrases useful in carbon capture systems
HK1209995A1 (en) 2012-06-21 2016-04-15 Novadaq Technologies Inc. Quantification and analysis of angiography and perfusion
MY193198A (en) 2013-04-18 2022-09-26 Codexis Inc Engineered phenylalanine ammonia lyase polypeptides
EP3201607B1 (en) 2014-09-29 2020-12-30 Novadaq Technologies ULC Imaging a target fluorophore in a biological material in the presence of autofluorescence
CA2963450A1 (en) 2014-10-09 2016-04-14 Novadaq Technologies Inc. Quantification of absolute blood flow in tissue using fluorescence-mediated photoplethysmography
CA3049922A1 (en) 2017-02-10 2018-08-16 Novadaq Technologies ULC Open-field handheld fluorescence imaging systems and methods
JP2020505942A (ja) 2017-02-13 2020-02-27 コデクシス， インコーポレイテッド フェニルアラニンアンモニアリアーゼポリペプチド

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH538003A (fr) * 1968-03-29 1973-01-31 Anvar Procédé pour l'obtention d'articles textiles porteurs d'enzymes
IT1096208B (it) * 1978-05-12 1985-08-26 Snam Progetti Composizione adatta alla riduzione del tenore di fenilalanina e metodo impiegante la stessa
FR2523445A1 (fr) * 1982-03-17 1983-09-23 Sanofi Sa Nouveaux conjugues associant, par liaison covalente, une enzyme et un anticorps, et associations medicamenteuses utilisant lesdits conjugues

Also Published As

Publication number Publication date
AU7067594A (en) 1995-01-17
DE69429167T2 (de) 2002-07-04
US5753487A (en) 1998-05-19
DK0703788T3 (da) 2002-05-21
EP0703788B1 (en) 2001-11-21
PT703788E (pt) 2002-05-31
DK75593D0 (enExample) 1993-06-25
CA2165281A1 (en) 1995-01-05
WO1995000171A1 (en) 1995-01-05
ES2168297T3 (es) 2002-06-16
EP0703788A1 (en) 1996-04-03
DE69429167D1 (de) 2002-01-03

Similar Documents

Publication Publication Date Title
DE69429167D1 (de) Eine stabilisierte phenylalanin-ammonia-lyase
DE69326250D1 (de) Neuropeptide y antagoniste
MY119820A (en) Guanidine mimics as factor xa inhibitors
NO971889L (no) Forbindelser og sammensetninger for levering av aktive midler
EP0528858A4 (en) Inhibitors of dipeptidyl-aminopeptidase type iv
DE69401204D1 (de) Gonadotropin enthaltende gefriergetrocknete troepfen
DE69830751D1 (de) Polyaromatische Verbindungen zur Behandlung von Herpes-Infektionen
MY118828A (en) Substituted amino compounds and their use as substances having an analgesic effect
DE69333016D1 (de) Rhamnogalacturonan acetylesterase (RGAE) von Aspergillus aculeatus
SI1028950T1 (en) 7-substituted quinazolin-2,4-diones useful as antibacterial agents
DK58291D0 (da) Krystalinsk stof og dets fremstilling
BR9913072A (pt) Sistemas de anel azacìclico, composição farmacêutica, e, processo para induzir a analgesia
DE69334146D1 (de) Peptide mit gdp-austauschfaktorartiger wirkung, dafür kodierende nukleinsäuresequenzen, ihre herstellung und verwendung
BR0111989A (pt) Peptìdeos, composições e processos para o tratamento de burkholderia cepacia
SE9101838D0 (sv) Novel peptides and their use
DE69808475D1 (de) Aminosäurederivate zur behandlung von schlaganfall
AU669149B2 (en) Expression signal-peptide-free staphylokinases
TR199701298T1 (xx) Tetralinler.
DK0651764T3 (da) Cytotoksisk T-lymfocytantigen som cysteinproteaseinhibitor
DE69333270D1 (de) Aminderivate von oxo- und hydroxy- substituierten kohlenwasserstoffen
ES2185154T3 (es) Metodo de uso de inhibidores de la ciclooxigenasa-2 en el tratamiento y prevencion de la demencia.
UA23046C2 (uk) Протимікробhий засіб
UA10504A (uk) N-(п-hітрофеhілсульфоhіл)біцикло[2.2.1]гепт-2-єhіл -еhдо-5-метиламіh, який має аhальгетичhу, протисудорожhу та траhквілізуючу дію
RU93055684A (ru) Соединения, ингибирующие вич-протеазу, способ их получения, фармацевтическая композиция, промежуточный продукт

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee